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Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets
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Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets

Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets

DOI:
10.3791/64413-v

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07:41 min

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September 13, 2022

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, , , , ,
1Department of Physiology,College of Medicine University of Tennessee Health Science Center

Chapters

  • 00:05Introduction
  • 01:13Experiment Group: Cecal Ligation and Perforation (CLP)
  • 02:35Transdermal GFR Device Setup
  • 03:49FITC-Sinistrin Preparation, Injection, and Transdermal GFR Recording
  • 04:43GFR Measurement
  • 05:47Results: Analysis of GFR Using Transdermal GFR Device
  • 07:02Conclusion

Summary

Automatic Translation

Automatic Translation

Glomerular filtration rate (GFR) is the ideal marker for assessing kidney function. However, the standard measurement method using inulin injection with serial blood and urine analysis is impractical. This article delineates a practical method to measure GFR transdermally in piglets.

Tags

Keywords: Transdermal GFR MeasurementKidney FunctionSwine ModelXenotransplantationPigletsCecal LigationTracheostomyVessel CannulationReal-time AssessmentNon-invasive

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