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En reproducerbar bruskpåvirkningsmodel til generering af posttraumatisk slidgigt hos kaninen
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En reproducerbar bruskpåvirkningsmodel til generering af posttraumatisk slidgigt hos kaninen

Article DOI: 10.3791/64450-v • 08:42 min • November 21st, 2023
November 21st, 2023 •
*1,2,3, *3,4,6, 1, 1,3, 1,3, 2,3, 1,2,3, 5, 2,3,6, 1,3
1Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 2Department of Orthopaedic Surgery, Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, 4School of Mechanical Engineering, Purdue University, 5Large Animal Resource Center, Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering, Indiana University-Purdue University Indianapolis
* These authors contributed equally

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Den åbne mediale femoral kondyle påvirkningsmodel hos kaniner er pålidelig til undersøgelse af posttraumatisk slidgigt (PTOA) og nye terapeutiske strategier til at afbøde PTOA progression. Denne protokol genererer en isoleret bruskdefekt af den bageste mediale lårbenskondyl hos kaniner ved anvendelse af et vognbaseret faldtårn med et slaghoved.

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