Journal
/
Cancer Research
/
Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations

Glioblastoma Relapse Post-Resection Model for Therapeutic Hydrogel Investigations

DOI:
10.3791/65026-v

•

04:46 min

•

February 24, 2023

•

, , , , , ,
1Department of Immunology, Key Laboratory of Human Functional Genomics of Jiangsu Province, Gusu School,Nanjing Medical University, 2Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine,Nanjing Medical University

Chapters

  • 00:04Introduction
  • 00:43Construction of Orthotopic Intracranial GBM model
  • 02:35Construction of the GBM Relapse Post‐Resection Model
  • 03:33Results: Tumor Resection and Recurrence in the Intracranial and Post‐Resection GBM Model
  • 04:17Conclusion

Summary

Automatic Translation

Automatic Translation

The present protocol establishes a glioblastoma (GBM) relapse post-resection model using microscopy to investigate the therapeutic effect of an injectable, bioresponsive hydrogel in vivo.

Tags

Keywords: GlioblastomaRelapsePost-resectionModelTherapeutic HydrogelTumor RecurrenceGBM Recurrence ModelLocal TreatmentAnimal PreparationStereotactic ApparatusTumor Cell SuspensionMicrosyringeBioluminescent ImagingOrthotopic Intracranial GBM Model

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/65026?article_type=v

Coculture Assays to Study Macrophage and Microglia Stimulation of Glioblastoma Invasion
check_url/65026?article_type=v

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
check_url/65026?article_type=v

Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts
check_url/65026?article_type=v

Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion
check_url/65026?article_type=v

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
check_url/65026?article_type=v

Enhanced Viability for Ex vivo 3D Hydrogel Cultures of Patient-Derived Xenografts in a Perfused Microfluidic Platform
check_url/65026?article_type=v

A 3D Spheroid Model for Glioblastoma
check_url/65026?article_type=v

Co-culture of Glioblastoma Stem-like Cells on Patterned Neurons to Study Migration and Cellular Interactions
check_url/65026?article_type=v

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
check_url/65026?article_type=v

Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma

Read Article