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Immunology and Infection

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JoVE Journal Immunology and Infection
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
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A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

Article DOI: 10.3791/65044-v • 09:12 min • February 3rd, 2023
February 3rd, 2023 •
1,2, 2, 2, 2, 1,2
1School of Medicine, South China University of Technology, 2Provincial Key Laboratory of Research in Structure Birth Defect Disease and Department of Pediatric Surgery, Guangzhou Women and Children’s Medical Center

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Summary
Automatic Translation

We established a mouse model of chronic liver fibrosis, which provides a suitable animal model for the virus-induced liver fibrosis mechanistic study of biliary atresia (BA) and a platform for future BA treatments.

Tags

Mouse Model Chronic Liver Fibrosis Biliary Atresia Pathology Antibody Therapy Neonatal Mice Intraperitoneal Injection Gr1-positive Cells Rhesus Rotavirus Saline Appearance Weight Survival Syringe Needle
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