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Journal / Medicine / Etablering af en enhed til søvnmangel hos mus
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JoVE Journal Medicine
Etablering af en enhed til søvnmangel hos mus
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Etablering af en enhed til søvnmangel hos mus

Article DOI: 10.3791/65157-v • 05:05 min • September 22nd, 2023
September 22nd, 2023 •
*1, *1, *2, *2, *2, 1,2
1Department of Cardiology, The First Affiliated Hospital of Bengbu Medical College, 2Department of Cardiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
* These authors contributed equally

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Denne protokol skitserer en metode til opsætning af en omkostningseffektiv vippeplatformbaseret enhed, der anvendes til at fremkalde søvnmangel hos mus. Denne enhed har vist sig at være effektiv til at forårsage forstyrrelser i elektroencefalogram (EEG) -dokumenterede søvnmønstre samt fremkalde metaboliske og molekylære ændringer forbundet med søvnmangel.

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Enhed til søvnmangel hos mus døgnrytmeforstyrrelse søvnmangelmetoder modaliteter til inducering af søvnmangel automatiseret Rocker Platform-baseret enhed justerbare tidsintervaller minimal stressrespons virkninger af søvnmangel på sundhed patogenese af flere sygdomme
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