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A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities

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Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application

JoVE Journal
Biochemistry

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JoVE Journal Biochemistry

An Open-Source Framework for Mass Calculation of Antibody-Based Therapeutic Molecules

Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application

A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities

DOI:

10.3791/65298-v

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01:35 min

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June 16, 2023

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Thomas Harkins², Li Cao, Kshitij Khatri³

¹GlaxoSmithKline, ²Merck, ³Moderna

Tags

Keywords: Open-source Framework Mass Calculation Antibody-based Therapeutics Monoclonal Antibodies Bispecific Antibodies Antibody-drug Conjugates Mass Spectrometry Protein Mass Biopharmaceutical Development Elemental Mass Modification List MapScale User-friendly Interface Adaptable Framework Proprietary Information Identity Verification Structural Integrity

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