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A Catheter-Related Candida albicans Infection Model in Mouse
A Catheter-Related <em>Candida albicans</em> Infection Model in Mouse
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
A Catheter-Related Candida albicans Infection Model in Mouse

A Catheter-Related Candida albicans Infection Model in Mouse

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03:24 min

March 22, 2024

DOI:

03:24 min
March 22, 2024

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Summary

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We establish a mouse model of C.albicans-associated catheter-related infection (CRI), in which biofilm forms on the catheter, and the interaction between C.albicans and host correlates well with the clinical CRI. This model helps screen therapies for C.albicans biofilm-associated CRI, laying a foundation for clinical transformation.

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