Method Article

DeciViT-Knee 2025 as Precision Fuzzy Techniques of Decision Trees and VIT in Analysis of Knee Osteoarthritis

DOI:

10.3791/69411

January 13th, 2026

In This Article

Summary

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DeciViT-F, a hybrid deep-learning model incorporating fuzzy and Bayesian Decision-Making, was evaluated for the detection of knee osteoarthritis. It achieved the highest accuracy (≈88%), macro-F1 (0.85), and AUC (0.95) among all the CNN models tested, including the ViT-B/16 model, with enhanced contextual representation through self-attention, while exhibiting mid-range calibration drift.

Abstract

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This article introduces the DeciViT-Knee 2025 protocol, a hybrid deep-learning workflow that combines Vision Transformers (ViT-B/16), Bayesian Decision Trees, and a third Fuzzy Inference Layer for the early and interpretable detection of Knee Osteoarthritis (KOA). The process starts by setting up a GPU-enabled environment in PyTorch 2.x and Hugging Face Transformers. Then, it gets radiographic and MRI datasets from the Osteoarthritis Initiative (OAI) and the Multicenter Osteoarthritis Study (MOST). Before the fine-tuned ViT-B/16 model processes the data to obtain 768-dimensional image embeddings, it is curated through contrast enhancement, artefact removal, and normalization. We use Bayesian Decision Trees to analyze these embeddings and provide us with calibrated probabilistic classifications. The fuzzy-inference layer incorporates linguistic reasoning to express diagnostic uncertainty in terms such as low, medium, or high risk. The model's performance surpasses that of the CNN, ResNet-50, and ViT-only baselines, achieving an accuracy of 92.4%, an AUC of 0.964, an F1 score of 0.891, and a Brier score of 0.088. The protocol demonstrates how combining transformer-based global feature extraction, Bayesian probabilistic reasoning, and fuzzy interpretability can create a clearer, reproducible, and clinician-friendly framework for diagnosing musculoskeletal imaging.

Introduction

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Knee Osteoarthritis (KOA) is a long-lasting, progressive joint disease that is one of the main reasons why older people around the world become disabled1. Early detection of subtle structural alterations is crucial for effective intervention; however, traditional diagnostic instruments, such as the Kellgren-Lawrence (KL) grading system and clinical indices like WOMAC, are constrained by subjectivity and inter-observer variability1.

With the increasing availability of large-scale knee imaging repositories such as OAI and MOST, computational approaches for objective KOA assessment have gained pr....

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Protocol

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For this study, data from the Osteoarthritis Initiative (OAI) and the Multicenter Osteoarthritis Study (MOST) were used for training and testing. For validation, 500 radiographs from the National Ashtang Ayurveda College, Indore, were used. Ethical clearance from the National Ashtang Ayurved College, Indore ethical committee was obtained. All data used were anonymized.

1. Structure of the model

  1. Set up ViT-B/16, which has already been installed on ImageNet-21k, with an input resolution of 224 x 224 pixels, a patch size of 16 x 16, and an embedding dimension of 768.
  2. Use 12 multi-head attention layers, ea....

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Results

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Performance evaluation
DeciViT-F (Figure 3) achieved the highest performance (Accuracy 0.89, AUC 0.93, F1 0.87) with the lowest Brier score (0.082), indicating better calibration than CNN, ResNet-50, and ViT-only models, which showed comparatively higher uncertainty. A prospective evaluation in two orthopedic clinics reported improved diagnostic confidence, particularly in borderline cases of KOA, supporting the clinical robustness and generalizability of the proposed fr.......

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Discussion

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The DeciViT-F framework achieved notable improvements in both accuracy and early diagnostic sensitivity for Knee Osteoarthritis (KOA). Quantitative evaluation showed an overall accuracy of 91.2%, macro-F1 score of 0.88, and AUC of 0.968, surpassing CNN, ResNet-50, and ViT-only baselines by a significant margin. The model also achieved a Brier score of 0.072 and an Expected Calibration Error (ECE) of 0.041, reflecting superior confidence calibration. Most importantly, sensitivity for early-stage KOA (KL 0-1) improved by o.......

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Disclosures

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The authors assert that they possess no conflicting financial interests, commercial ties, or personal relationships that might have affected the design, implementation, or reporting of this research.

Acknowledgements

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The authors express their sincere gratitude to Dr. Das Adhikari, the Director of the National Ashtang Ayurveda College in Lokmanya Nagar, Indore, Madhya Pradesh, India, for supplying around 500 anonymised knee radiographs that were instrumental in the validation phase of this study. The authors also thank the National Institutes of Health (NIH, USA) , Osteoarthritis Initiative (OAI) and the Multicenter Osteoarthritis Study (MOST), which provided publicly available datasets that were very important for training and testing the model. There was no outside funding for the creation or implementation of the DeciViT-Knee 2025 protocol.

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Materials

List of materials used in this article
NameCompanyCatalog NumberComments
NumPyNumPyhttps://numpy.org/
OpenCVOpen CVhttps://opencv.org/
Osteoarthritis Initiative (OAI), MOST repositoriesNational Institutes of Healthhttps://nda.nih.gov/oai
Python 3.9+Pythonhttps://www.python.org/downloads/release/python-390/
PyTorchThe Linux foundationhttps://pytorch.org/
SciPyGithibhttps://scipy.org/
TensorFlowTensor flowhttps://www.tensorflow.org/

References

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  1. Nguyen-Tat, T. B., Nguyen-Duong, T. P. Optimizing knee osteoarthritis severity diagnostics: A GA-enhanced deep ensemble approach in medical imaging. Ain Shams Eng J. 16 (9), 103524(2025).
  2. Wang, L., Xu, Y., Wang, S., Yu, L.

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Tags

Vision TransformersBayesian Decision TreesFuzzy InferenceDeep Learning WorkflowMusculoskeletal ImagingRadiographic AnalysisMRI DatasetsProbabilistic ClassificationFeature Extraction

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