Here, we analyze the impact of a nursing intervention of case management (CM) combined with cognitive-behavioral therapy (CBT) on anxiety and depression and quality of life in postoperative non-small cell lung cancer (NSCLC) patients.
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Research Article
Here, we analyze the impact of a nursing intervention of case management (CM) combined with cognitive-behavioral therapy (CBT) on anxiety and depression and quality of life in postoperative non-small cell lung cancer (NSCLC) patients.
Non-small cell lung cancer (NSCLC) is characterized by high morbidity and lethality, causing a great physical and psychological burden on patients. Therefore, effective treatment of NSCLC patients is very important.
This study analyzes the impact of a nursing intervention of case management combined with cognitive-behavioral therapy on anxiety and depression and quality of life in postoperative NSCLC patients. A single-center, non-randomized controlled study in which 80 NSCLC patients from the Hospital were enrolled from May 2023 to January 2024, and were categorized into case management (CM) and cognitive-behavioral therapy (CBT) groups depending on treatment modalities, with case management care in both groups, and cognitive-behavioral therapy care added to the CM combined with CBT (CC) group.
The Hamilton anxiety scale (HAMA), Hamilton depression scale (HAMD), self-perception burden scale (SPBS), life qualities (QLQ-C30), neurotransmitter levels, and clinical effectiveness were primarily assessed in both groups post-treatment. Secondary outcomes included pain level (VAS score), nursing satisfaction, adverse events, and complications.
After treatment, the indicators of both groups were significantly different from those of the pre-treatment. Post-treatment, the CC group demonstrated significantly lower scores than the CM group in HAMA (10.18 ± 2.10 vs. 16.04 ± 3.89), HAMD (11.94 ± 2.91 vs. 16.81 ± 3.19), and SPBS (25.52 ± 3.17 vs. 33.50 ± 5.61) (all P < 0.05). Conversely, the CC group showed significantly higher QLQ-C30 scores and levels of 5-hydroxytryptamine (5-HT) and brain-derived neurotrophic factor (BDNF). The nursing intervention of case management combined with cognitive behavioral therapy has a good improvement effect on the anxiety and depression status of NSCLC patients. It can improve the quality of life, which is worth promoting and using in the clinic.
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, named for the larger, cytoplasm-rich cells under the microscope, and accounts for about 85% of all lung cancer cases. It encompasses various histologic subtypes such as squamous carcinoma, adenocarcinoma, large cell carcinoma, squamous adenocarcinoma, and sarcomatoid carcinoma1,2. The etiology of its development is complex. Smoking is a key risk factor. Long-term smoking contributes to the abnormal proliferation of bronchial mucosal epithelial cells. Up to 85% of lung cancer deaths can be attributed to smoking, and the risk of lung canc....
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The study was performed in compliance with the Declaration of Helsinki and the hospital's ethical guidelines and was endorsed by the hospital's ethical committees (Ethics approval number: 2023003).
Study design:
This study was a single-center, non-randomized controlled study designed to systematically assess and integrate relevant outcomes, aiming to analyze the efficacy of the combination of CMN and CBT in the treatment of patients with NSCLC, and to further assess its impact on patients' anxiety and depression and quality of life. The study was evaluated by multidimensional measurement tools, before and after treatmen....
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Basic information
In this study, 80 patients with NSCLC from May 2023 to January 2024 were categorized into the CM group (n = 40) and CC group (n = 40) depending on different interventions. The baseline demographic and baseline characteristics in the two groups are displayed in Table 1, and these characteristics were not significantly different between the groups (P > 0.05). Therefore, both groups were comparable at the pre-treatment level, and the confo.......
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NSCLC, as the most common type of lung cancer, accounts for about 80% of all lung cancer patients. NSCLC covers a wide range of pathological types, such as squamous, adenocarcinoma, and large-cell carcinoma, and there are significant differences in biological behavior, treatment response, and prognosis among different types35. The clinical presentation of NSCLC patients varies depending on the stage of the disease. In the early stage, patients may have no obvious symptoms or only mild cough, sputu.......
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The authors declare that they have no financial conflicts of interest.
The authors acknowledge the funding support from;
1. 2025 Henan Provincial Science and Technology Research Project: Mechanistic Study on the Suppression of Malignant Behaviors in Lung Cancer by the Novel Immune Checkpoint Molecule TIPE2 and Development of Protein-Based Therapeutics(Grant No. 252102310130).
2. 2024 Henan Provincial Science and Technology Research Project: Pathogenic Mechanisms and Applications of the Immune Negative Regulator TIPE2 in Lung Cancer(Grant No. 242102310240).
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| Name | Company | Catalog Number | Comments |
|---|---|---|---|
| Human 5-HT ELISA assay kit | Shanghai COIBO Bio-Technology Co Ltd. | CB10030-Hu | |
| Human BDNF ELISA assay kit | Shanghai COIBO Bio-Technology Co Ltd. | CB12019-Hu |
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