$$\rightleftharpoonup{xx}$$
$$\longleftharp{xx}$$,
$$\longrightharp{xx}$$,
Study participants
Elderly patients with DM who visited the Department of Medical Affairs of Tian Shui Wulin Street Community Health Service Center, Hangzhou, from January 2024 to February 2025 were enrolled in the study, totaling 167 cases (82 in the observation group and 85 in the control group). Inclusion criteria: Age ≥ 60 years; meeting the diagnostic criteria for T2DM11; presenting with at least one cardiovascular risk factor (hypertension, dyslipidemia, obesity, or family history of premature cardiovascular disease); being conscious, with basic communication skills, and able to operate multimedia platforms independently or with family assistance. Exclusion criteria: Type 1 DM or special types of DM; serious hepatic or renal impairment (ALT/AST > 3x the upper limit of normal, Cr > 177 µmol/L); psychiatric disorders or cognitive impairment preventing cooperation; ≥3 hospitalizations within the past 6 months or scheduled for surgical intervention. The study has been approved by the Ethics Committee of the hospital, and all the participants have signed the informed consent form.
Grouping method
A retrospective cohort analysis was conducted, dividing patients into two groups based on whether they received "multimedia platform-based home care." The observation group included patients who sought medical care after August 2024, voluntarily participated in the hospital's "Home Management Multimedia Platform for DM" project, and received standardized home care for 6 months The control group consisted of patients who sought medical attention from January to August 2024, received only routine outpatient follow-up (every 3 months), and did not use the multimedia platform. Patients admitted between January and August 2024 had completed their routine outpatient follow-up procedures before the official launch of the multimedia platform program in August 2024 and thus were not eligible for enrollment in the intervention group. The two patient groups showed no statistically significant differences in age, gender, disease duration, baseline blood glucose levels, or cardiovascular risk factors (P > 0.05), indicating comparable baseline characteristics (see Table 1).
Intervention
Routine outpatient follow-up: Outpatient visits were scheduled once every 3 months, including blood glucose testing, medication adjustments, and distribution of printed health manuals. No remote monitoring or video follow-ups were conducted.
Multimedia platform-based home care: A WeChat mini-program (APP) independently developed by the hospital was used (https://weixin.ngarihealth.com/weixin/wx/mp/wx87e933682e320dea/index.html?pageModule=secHomepage). The mini-program included multiple functional modules to support home-based diabetes management. The data monitoring module enabled automatic synchronization of fasting and 2 h postprandial blood glucose levels, as well as blood pressure measurements, from Bluetooth-enabled glucometers. Abnormal values (e.g., blood glucose >13.9 mmol/L or <3.9 mmol/L) triggered real-time alerts through application notifications and SMS messages to healthcare providers.
A medication management module provided individualized medication schedules, including drug names, dosages, and administration frequencies, with automated reminders delivered 15 min before dosing using voice and vibration alerts. A complication self-assessment module incorporated structured flowcharts to support screening for diabetic retinopathy, peripheral neuropathy, and foot ulcers, using images and short videos, along with monthly AI-assisted voice-guided assessments. An emergency contact module allowed patients to quickly connect with family members, community physicians, and specialist nurses, including access to one-touch video consultation.
Health education content was delivered twice weekly (Monday and Thursday) through the application, using brief text (≤300 words) combined with images or short videos (≤3 min). Content included practical topics such as dietary guidance (e.g., seasonal glycemic control recipes) and simple exercise demonstrations (e.g., seated lower-limb exercises). In addition, monthly live online sessions were conducted by endocrinologists and nutritionists.
For glycemic management, patients were instructed to upload blood glucose measurements twice daily (fasting and postprandial). Nursing staff reviewed the data and provided feedback within 48 h to adjust individualized glycemic targets (fasting 7.0–8.0 mmol/L; postprandial <10.0 mmol/L), with emphasis on safety in elderly patients. Pharmacists provided online consultations to evaluate potential drug interactions, particularly in patients receiving five or more medications.
Dietary management followed a structured “3 + 3” model, consisting of three main meals with controlled portions of staples and three low-glycemic snacks. A visual “blood glucose control plate” model (vegetables: protein: staples = 2:1:1) was provided weekly. The intervention was conducted over a 6-month period in both groups.
Resource requirements for the intervention
The implementation of the multimedia platform intervention required one full-time project manager, two specialized diabetes nurses, one part-time clinical pharmacist, one part-time endocrinologist, and one part-time nutritionist. The WeChat mini-program was developed and maintained by the hospital's information technology department, with a one-time development cost of approximately 15,000 USD and an annual maintenance cost of 2,000 USD.
Data source
The data were retrospectively extracted from the hospital electronic medical record system (HIS), multimedia platform backend database, and follow-up records.
Intervention adherence metrics
Pre-specified platform usage indicators were used to assess adherence to the multimedia platform intervention, with standardized definitions as follows: 1. Monthly platform login frequency: The total number of successful patient logins to the WeChat mini-program per calendar month during the 6-month intervention period, reported as the mean value across the full 6-month intervention. 2. Valid blood glucose upload rate: The percentage of valid blood glucose readings uploaded by patients relative to the total required readings during the intervention period. Per the intervention protocol, patients were required to upload 2 valid readings per day (1 fasting, 1 2 h postprandial), totaling 360 readings over the 6-month intervention. Valid readings were defined as values within the physiological measurement range of the study's standardized Bluetooth glucometer, with clear fasting/postprandial time labeling, excluding duplicate or invalid test results. 3. Video follow-up participation rate: The percentage of planned online video-based interactions attended by patients during the intervention period, including the monthly live expert Q&A sessions (6 total sessions over 6 months) and scheduled video follow-up consultations with the diabetes care team.
Outcome measures
Blood glucose and lipid parameters, including HbA1c, FPG, 2hPG, TC, TG, LDL-C, and HDL-C, were recorded before the intervention and at 3 and 6 months. Cardiovascular complications (e.g., heart failure, angina pectoris) occurring during the intervention were statistically documented. All cardiovascular events were adjudicated independently by two board-certified cardiologists unaware of group assignments. Discrepancies in event classification were resolved by consensus with a third senior cardiologist. Patient frailty status before and after intervention was recorded using the Fried frailty phenotype12: 1. Unintentional weight loss: ≥4.5 kg (or ≥5% of body weight) loss in the previous 12 months; 2. Exhaustion: self-reported positive response to either of two items from the Center for Epidemiologic Studies Depression Scale (CES-D); 3. Weakness: decreased grip strength, stratified by gender and body mass index (BMI) per the original phenotype thresholds; 4. Slowness: decreased walking speed over a 4 m walk, stratified by sex and height per the original phenotype thresholds; 5. Low physical activity: sex-specific low weekly energy expenditure, defined as <383 kcal/week for men and <270 kcal/week for women. Meeting ≥3 of the 5 criteria was defined as "frailty"; meeting 1–2 criteria was defined as "pre-frailty"; and meeting 0 criteria was defined as "non-frailty." At 6 months, patients completed the Summary of Diabetes Self-Care Activities Scale (SDSCA)13, which assesses five domains: blood glucose testing, diet, exercise, medications, and foot care. Higher scores indicate better self-management ability. Concurrently, patients were required to complete the Short Form 36 Health Survey (SF-36)14. There are eight dimensions: Physical Functioning (PF), Role-Physical (RP), Bodily Pain (BP), General Health (GH), Vitality (VT), Social Functioning (SF), Role-Emotional (RE), Mental Health (MH); higher scores indicate a better quality of life.
Statistical analysis
Enumeration data were recorded as [n (%)] and compared using the chi-square test. Measurement data were first assessed for distribution (Shapiro-Wilk test); normally distributed data were recorded as (x̄ ± s) and compared using independent samples t-tests (between groups) and paired t-tests (within groups); non-normally distributed data were recorded as [M (P25, P75)] and compared using the Mann-Whitney U tests (between groups) and Wilcoxon tests (within groups). The comparison at multiple time points was conducted using the repeated strategy analysis of variance and the Bonferroni intra-group test. P < 0.05 was considered statistically significant.