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Journal / Developmental Biology / Protokol for differensiering av humane inducerte…
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Developmental Biology

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JoVE Journal Developmental Biology
Protokol for differensiering av humane inducerte pluripotente stamceller i blandede kulturer av neuroner og glia for test av neurotoxicitet
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Protokol for differensiering av humane inducerte pluripotente stamceller i blandede kulturer av neuroner og glia for test av neurotoxicitet

Article DOI: 10.3791/55702-v • 09:02 min • June 9th, 2017
June 9th, 2017 •
1, 1, 1, 1
1Directorate F - Health, Consumers and Reference Materials, Joint Research Centre

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Menneskeinducerte pluripotente stamceller (hiPSCs) anses som et kraftig verktøy for stoff- og kjemisk screening og for utvikling av nye in vitro- modeller for toksisitetstesting, inkludert nevrotoksisitet. Her beskrives en detaljert protokoll for differensiering av hiPSCs i nevroner og glia.

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Utviklingsbiologi utgave 124 humant indusert pluripotente stamceller differensiering nevroner glia nevrotoksisitet Nrf2-pathway aktivering
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