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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
JoVE Journal
Medicine
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JoVE Journal Medicine
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
DOI:

09:12 min

March 27, 2018

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Chapters

  • 00:04Title
  • 00:49Hibernation Surgery
  • 03:30Off Pump Coronary Artery Bypass
  • 06:53Results: Representative Cardiac Magnetic Resonance Imaging (MRI) and Wall Thickening Measurement
  • 07:49Conclusion

Summary

Automatic Translation

This protocol presents a surgical large animal model of chronic, single vessel ischemia that results in regional abnormalities but does not create infarct, known as hibernating myocardium. Following establishment of chronic ischemia, animals are treated with off-pump LIMA-LAD coronary artery bypass graft surgery to revascularize the ischemic tissue.

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