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Bioengineering

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JoVE Journal Bioengineering
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Spontaneous Formation and Rearrangement of Artificial Lipid Nanotube Networks as a Bottom-Up Model for Endoplasmic Reticulum

Article DOI: 10.3791/58923-v • 07:49 min • January 22nd, 2019
January 22nd, 2019 •
1, 1, 1, 1, 1, 1, 1,2,3
1Centre for Molecular Medicine Norway, Faculty of Medicine, University of Oslo, 2Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Oslo, 3Department of Chemistry and Chemical Engineering, Chalmers University of Technology

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Summary
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Solid-supported, protein-free, double phospholipid bilayer membranes (DLBM) can be transformed into complex and dynamic lipid nanotube networks and can serve as 2D bottom-up models of the endoplasmic reticulum.

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Spontaneous Formation Rearrangement Artificial Lipid Nanotube Networks Bottom-up Model Endoplasmic Reticulum ER Organization Solid-supported Protein-free Membrane System Complex Lipid Nanotubes Hydrophilics Organic Compound Energy Protein Purification Protein Extraction Solid Substrate Phospholipids ER Model Inverted Pear-shaped Flask Lipids Chloroform Rotary Evaporator Air Pressure
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