Alain Filloux MRC Centre for Molecular Bacteriology and Infection, Division of Cell and Molecular Biology Imperial College London Biography Publications Institution JoVE Articles Alain Filloux has not added a biography. If you are Alain Filloux and would like to personalize this page please email our Author Liaison for assistance. Publications Microbiology. Editorial FEMS Microbiology Reviews. Mar, 2013 | Pubmed ID: 23362803 The HsiB1C1 (TssB-TssC) Complex of the Pseudomonas Aeruginosa Type VI Secretion System Forms a Bacteriophage Tail Sheathlike Structure The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23341461 The P110δ Isoform of the Kinase PI(3)K Controls the Subcellular Compartmentalization of TLR4 Signaling and Protects from Endotoxic Shock Nature Immunology. Nov, 2012 | Pubmed ID: 23023391 The Archetype Pseudomonas Aeruginosa Proteins TssB and TagJ Form a Novel Subcomplex in the Bacterial Type VI Secretion System Molecular Microbiology. Oct, 2012 | Pubmed ID: 22906320 Type II-dependent Secretion of a Pseudomonas Aeruginosa DING Protein Research in Microbiology. Jul, 2012 | Pubmed ID: 22835944 The Second Type VI Secretion System of Pseudomonas Aeruginosa Strain PAO1 is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22665491 On the Path to Uncover the Bacterial Type II Secretion System Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Apr, 2012 | Pubmed ID: 22411978 The Pseudomonas Aeruginosa Reference Strain PA14 Displays Increased Virulence Due to a Mutation in LadS PloS One. 2011 | Pubmed ID: 22216178 The Pseudomonas Aeruginosa Sensor RetS Switches Type III and Type VI Secretion Via C-di-GMP Signalling Environmental Microbiology. Dec, 2011 | Pubmed ID: 21955777 The Cyst-dividing Bacterium Ramlibacter Tataouinensis TTB310 Genome Reveals a Well-stocked Toolbox for Adaptation to a Desert Environment PloS One. 2011 | Pubmed ID: 21912644 Structure-function Analysis of HsiF, a Gp25-like Component of the Type VI Secretion System, in Pseudomonas Aeruginosa Microbiology (Reading, England). Dec, 2011 | Pubmed ID: 21873404 Protein Secretion Systems in Pseudomonas Aeruginosa: An Essay on Diversity, Evolution, and Function Frontiers in Microbiology. 2011 | Pubmed ID: 21811488 The Assembly Mode of the Pseudopilus: a Hallmark to Distinguish a Novel Secretion System Subtype The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21586577 Key Two-component Regulatory Systems That Control Biofilm Formation in Pseudomonas Aeruginosa Environmental Microbiology. Jul, 2011 | Pubmed ID: 21554516 Type VI Secretion System in Pseudomonas Aeruginosa: Secretion and Multimerization of VgrG Proteins The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21325275 Structural and Functional Characterization of Pseudomonas Aeruginosa CupB Chaperones PloS One. 2011 | Pubmed ID: 21304995 Two-component Regulatory Systems in Pseudomonas Aeruginosa: an Intricate Network Mediating Fimbrial and Efflux Pump Gene Expression Molecular Microbiology. Mar, 2011 | Pubmed ID: 21205015 The PprA-PprB Two-component System Activates CupE, the First Non-archetypal Pseudomonas Aeruginosa Chaperone-usher Pathway System Assembling Fimbriae Environmental Microbiology. Mar, 2011 | Pubmed ID: 21091863 Chemical Analysis of Cellular and Extracellular Carbohydrates of a Biofilm-forming Strain Pseudomonas Aeruginosa PA14 PloS One. 2010 | Pubmed ID: 21151973 Protein Secretion Systems in Pseudomonas Aeruginosa: A Wealth of Pathogenic Weapons International Journal of Medical Microbiology : IJMM. Dec, 2010 | Pubmed ID: 20947426 Distinct Oligomeric Forms of the Pseudomonas Aeruginosa RetS Sensor Domain Modulate Accessibility to the Ligand Binding Site Environmental Microbiology. Jun, 2010 | Pubmed ID: 20553556 Secretion Signal and Protein Targeting in Bacteria: a Biological Puzzle Journal of Bacteriology. Aug, 2010 | Pubmed ID: 20525826 A Variety of Bacterial Pili Involved in Horizontal Gene Transfer Journal of Bacteriology. Jul, 2010 | Pubmed ID: 20418394 Regulatory RNAs and the HptB/RetS Signalling Pathways Fine-tune Pseudomonas Aeruginosa Pathogenesis Molecular Microbiology. Jun, 2010 | Pubmed ID: 20398205 High-level Antibiotic Resistance in Pseudomonas Aeruginosa Biofilm: the NdvB Gene is Involved in the Production of Highly Glycerol-phosphorylated Beta-(1->3)-glucans, Which Bind Aminoglycosides Glycobiology. Jul, 2010 | Pubmed ID: 20348539 The Pseudomonas Aeruginosa Patatin-like Protein PlpD is the Archetype of a Novel Type V Secretion System Environmental Microbiology. Jun, 2010 | Pubmed ID: 20192961 The C-terminal Amphipathic Alpha-helix of Pseudomonas Aeruginosa PelC Outer Membrane Protein is Required for Its Function Biochimie. Jan, 2010 | Pubmed ID: 19853003 Structure of the Pseudomonas Aeruginosa XcpT Pseudopilin, a Major Component of the Type II Secretion System Journal of Structural Biology. Jan, 2010 | Pubmed ID: 19747550 The XcpV/GspI Pseudopilin Has a Central Role in the Assembly of a Quaternary Complex Within the T2SS Pseudopilus The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19828448 HxcQ Liposecretin is Self-piloted to the Outer Membrane by Its N-terminal Lipid Anchor The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19815547 Caenorhabditis Elegans Semi-automated Liquid Screen Reveals a Specialized Role for the Chemotaxis Gene CheB2 in Pseudomonas Aeruginosa Virulence PLoS Pathogens. Aug, 2009 | Pubmed ID: 19662168 Expression of Pseudomonas Aeruginosa CupD Fimbrial Genes is Antagonistically Controlled by RcsB and the EAL-containing PvrR Response Regulators PloS One. 2009 | Pubmed ID: 19547710 The Type VI Secretion System: a Tubular Story The EMBO Journal. Feb, 2009 | Pubmed ID: 19225443 Direct Interaction Between Sensor Kinase Proteins Mediates Acute and Chronic Disease Phenotypes in a Bacterial Pathogen Genes & Development. Jan, 2009 | Pubmed ID: 19171785 Organization and PprB-dependent Control of the Pseudomonas Aeruginosa Tad Locus, Involved in Flp Pilus Biology Journal of Bacteriology. Mar, 2009 | Pubmed ID: 19151143 Identification of Biofilm-associated Cluster (bac) in Pseudomonas Aeruginosa Involved in Biofilm Formation and Virulence PloS One. 2008 | Pubmed ID: 19065261 The 'P-usher', a Novel Protein Transporter Involved in Fimbrial Assembly and TpsA Secretion The EMBO Journal. Oct, 2008 | Pubmed ID: 18833195 The Bacterial Type VI Secretion Machine: Yet Another Player for Protein Transport Across Membranes Microbiology (Reading, England). Jun, 2008 | Pubmed ID: 18524912 Emergence of Secretion-defective Sublines of Pseudomonas Aeruginosa PAO1 Resulting from Spontaneous Mutations in the Vfr Global Regulatory Gene Applied and Environmental Microbiology. Mar, 2008 | Pubmed ID: 18203852 PelC is a Pseudomonas Aeruginosa Outer Membrane Lipoprotein of the OMA Family of Proteins Involved in Exopolysaccharide Transport Biochimie. Aug, 2007 | Pubmed ID: 17524545 Interaction Domains in the Pseudomonas Aeruginosa Type II Secretory Apparatus Component XcpS (GspF) Microbiology (Reading, England). May, 2007 | Pubmed ID: 17464073 XphA/XqhA, a Novel GspCD Subunit for Type II Secretion in Pseudomonas Aeruginosa Journal of Bacteriology. May, 2007 | Pubmed ID: 17351035 Expression Level of Heterologous Tat Genes is Crucial for in Vivo Reconstitution of a Functional Tat Translocase in Escherichia Coli Biochimie. May, 2007 | Pubmed ID: 17336443 Cross Talk Between Type III Secretion and Flagellar Assembly Systems in Pseudomonas Aeruginosa Journal of Bacteriology. Apr, 2007 | Pubmed ID: 17307856 Assembly of Fimbrial Structures in Pseudomonas Aeruginosa: Functionality and Specificity of Chaperone-usher Machineries Journal of Bacteriology. May, 2007 | Pubmed ID: 17293418 Export of the Pseudopilin XcpT of the Pseudomonas Aeruginosa Type II Secretion System Via the Signal Recognition Particle-Sec Pathway Journal of Bacteriology. Mar, 2007 | Pubmed ID: 17172336 [Two Sensors to Control Bacterial Life Style: the Choice Between Chronic or Acute Infection] Médecine Sciences : M/S. Oct, 2006 | Pubmed ID: 17026928 FppA, a Novel Pseudomonas Aeruginosa Prepilin Peptidase Involved in Assembly of Type IVb Pili Journal of Bacteriology. Jul, 2006 | Pubmed ID: 16788194 Pyoverdine-mediated Iron Uptake in Pseudomonas Aeruginosa: the Tat System is Required for PvdN but Not for FpvA Transport Journal of Bacteriology. May, 2006 | Pubmed ID: 16621825 Multiple Sensors Control Reciprocal Expression of Pseudomonas Aeruginosa Regulatory RNA and Virulence Genes Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16373506 Subcomplexes from the Xcp Secretion System of Pseudomonas Aeruginosa FEMS Microbiology Letters. Nov, 2005 | Pubmed ID: 16168578 XcpX Controls Biogenesis of the Pseudomonas Aeruginosa XcpT-containing Pseudopilus The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 16012171 Role of XcpP in the Functionality of the Pseudomonas Aeruginosa Secreton Research in Microbiology. Sep, 2005 | Pubmed ID: 15936176 Quorum Sensing Negatively Controls Type III Secretion Regulon Expression in Pseudomonas Aeruginosa PAO1 Journal of Bacteriology. Jun, 2005 | Pubmed ID: 15901720 The Pel Genes of the Pseudomonas Aeruginosa PAK Strain Are Involved at Early and Late Stages of Biofilm Formation Microbiology (Reading, England). Mar, 2005 | Pubmed ID: 15758243 A Novel Two-component System Controls the Expression of Pseudomonas Aeruginosa Fimbrial Cup Genes Molecular Microbiology. Jan, 2005 | Pubmed ID: 15659157 The Underlying Mechanisms of Type II Protein Secretion Biochimica Et Biophysica Acta. Nov, 2004 | Pubmed ID: 15546665 A Novel Extracellular Phospholipase C of Pseudomonas Aeruginosa is Required for Phospholipid Chemotaxis Molecular Microbiology. Aug, 2004 | Pubmed ID: 15306013 Biofilm Formation in Pseudomonas Aeruginosa: Fimbrial Cup Gene Clusters Are Controlled by the Transcriptional Regulator MvaT Journal of Bacteriology. May, 2004 | Pubmed ID: 15090530 [Biofilm: Set-up and Organization of a Bacterial Community] Médecine Sciences : M/S. Jan, 2003 | Pubmed ID: 12836195 Type II Protein Secretion in Pseudomonas Aeruginosa: the Pseudopilus is a Multifibrillar and Adhesive Structure Journal of Bacteriology. May, 2003 | Pubmed ID: 12700254 Virulence Factors of the Human Opportunistic Pathogen Serratia Marcescens Identified by in Vivo Screening The EMBO Journal. Apr, 2003 | Pubmed ID: 12660152 Type III Secretion-mediated Killing of Endothelial Cells by Pseudomonas Aeruginosa Microbial Pathogenesis. Oct, 2002 | Pubmed ID: 12385743 Identification of XcpP Domains That Confer Functionality and Specificity to the Pseudomonas Aeruginosa Type II Secretion Apparatus Molecular Microbiology. Jun, 2002 | Pubmed ID: 12067351 A Novel Type II Secretion System in Pseudomonas Aeruginosa Molecular Microbiology. Jan, 2002 | Pubmed ID: 11985723 In Vivo Dissection of the Tat Translocation Pathway in Escherichia Coli Journal of Molecular Biology. Mar, 2002 | Pubmed ID: 11922668 A Visual Assay to Monitor T6SS-mediated Bacterial Competition Abderrahman Hachani1, Nadine S. Lossi1, Alain Filloux1 1MRC Centre for Molecular Bacteriology and Infection, Division of Cell and Molecular Biology, Imperial College London JoVE 50103 Immunology and Infection
A Visual Assay to Monitor T6SS-mediated Bacterial Competition Abderrahman Hachani1, Nadine S. Lossi1, Alain Filloux1 1MRC Centre for Molecular Bacteriology and Infection, Division of Cell and Molecular Biology, Imperial College London JoVE 50103 Immunology and Infection