Alfredo Nicosia Department of Molecular Medicine and Medical Biotechnology University of Naples Federico II Biography Publications Institution JoVE Articles Alfredo Nicosia has not added a biography. If you are Alfredo Nicosia and would like to personalize this page please email our Author Liaison for assistance. Publications Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Oncolytic Virus Cancers. Nov, 2020 | Pubmed ID: 33213060 Optimising T Cell (re)boosting Strategies for Adenoviral and Modified Vaccinia Ankara Vaccine Regimens in Humans NPJ Vaccines. 2020 | Pubmed ID: 33083029 Isolation of Two Novel Human Anti-CTLA-4 MAbs with Intriguing Biological Properties on Tumor and NK Cells Cancers. Aug, 2020 | Pubmed ID: 32781690 A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability Cancer Research. Sep, 2020 | Pubmed ID: 32690723 MHC Class II Invariant Chain-adjuvanted Viral Vectored Vaccines Enhances T Cell Responses in Humans Science Translational Medicine. Jun, 2020 | Pubmed ID: 32554708 Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries BioMed Research International. 2019 | Pubmed ID: 31976323 Novel Human Anti-PD-L1 MAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling Scientific Reports. 09, 2019 | Pubmed ID: 31511565 Adenoviral Vaccine Targeting Multiple Neoantigens As Strategy to Eradicate Large Tumors Combined with Checkpoint Blockade Nature Communications. 06, 2019 | Pubmed ID: 31217437 Longitudinal Transcriptomic and Genetic Landscape of Radiotherapy Response in Canine Melanoma Veterinary and Comparative Oncology. Sep, 2019 | Pubmed ID: 30805995 Novel Genetically-modified Chimpanzee Adenovirus and MVA-vectored Respiratory Syncytial Virus Vaccine Safely Boosts Humoral and Cellular Immunity in Healthy Older Adults The Journal of Infection. 05, 2019 | Pubmed ID: 30742894 Antigen-specific CD8 T Cells in Cell Cycle Circulate in the Blood After Vaccination Scandinavian Journal of Immunology. Feb, 2019 | Pubmed ID: 30488973 A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection Frontiers in Immunology. 2018 | Pubmed ID: 30713538 Massive Parallel Screening of Phage Libraries for the Generation of Repertoires of Human Immunomodulatory Monoclonal Antibodies MAbs. 10, 2018 | Pubmed ID: 29995563 Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome JAMA Oncology. 08, 2018 | Pubmed ID: 29710228 Assessment of Novel Vaccination Regimens Using Viral Vectored Liver Stage Malaria Vaccines Encoding ME-TRAP Scientific Reports. 02, 2018 | Pubmed ID: 29467399 Incidence and Risk Factors for Hepatitis C Virus Infection Among Illicit Drug Users in Italy Journal of Urban Health : Bulletin of the New York Academy of Medicine. 02, 2018 | Pubmed ID: 29204843 Chimpanzee Adenoviral Vectors As Vaccines - Challenges to Move the Technology into the Fast Lane Expert Review of Vaccines. 12, 2017 | Pubmed ID: 29047309 Human Vaccination Against Plasmodium Vivax Duffy-binding Protein Induces Strain-transcending Antibodies JCI Insight. Jun, 2017 | Pubmed ID: 28614791 Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication EBioMedicine. Apr, 2017 | Pubmed ID: 28302457 Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb/Mar, 2017 | Pubmed ID: 28166180 Chimpanzee Adenovirus Vector Ebola Vaccine The New England Journal of Medicine. 03, 2017 | Pubmed ID: 25426834 Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV During Chronic Infection Vaccines. Aug, 2016 | Pubmed ID: 27490575 Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2016 | Pubmed ID: 27109630 Novel Human Anti-claudin 1 MAbs Inhibit Hepatitis C Virus Infection and May Synergize with Anti-SRB1 MAb The Journal of General Virology. Jan, 2016 | Pubmed ID: 26519290 Chronic Hepatitis C Viral Infection Subverts Vaccine-induced T-cell Immunity in Humans Hepatology (Baltimore, Md.). May, 2016 | Pubmed ID: 26474390 Targeting a Host-cell Entry Factor Barricades Antiviral-resistant HCV Variants from On-therapy Breakthrough in Human-liver Mice Gut. 12, 2016 | Pubmed ID: 26306759 A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA The New England Journal of Medicine. Apr, 2016 | Pubmed ID: 25629663 Persistent HCV Replication Despite Priming of Functional CD8+ T Cells by Combined Therapy with a Vaccine and Direct Acting Antiviral Hepatology (Baltimore, Md.). Oct, 2015 | Pubmed ID: 26513111 Cholesterol Conjugation Potentiates the Antiviral Activity of an HIV Immunoadhesin Journal of Peptide Science : an Official Publication of the European Peptide Society. Sep, 2015 | Pubmed ID: 26292842 Chimpanzee Adenovirus- and MVA-vectored Respiratory Syncytial Virus Vaccine is Safe and Immunogenic in Adults Science Translational Medicine. Aug, 2015 | Pubmed ID: 26268313 Prime-boost Vaccination with Chimpanzee Adenovirus and Modified Vaccinia Ankara Encoding TRAP Provides Partial Protection Against Plasmodium Falciparum Infection in Kenyan Adults Science Translational Medicine. May, 2015 | Pubmed ID: 25947165 Anti-CD81 but Not Anti-SR-BI Blocks Plasmodium Falciparum Liver Infection in a Humanized Mouse Model The Journal of Antimicrobial Chemotherapy. 2015 | Pubmed ID: 25656410 Antigen Expression Determines Adenoviral Vaccine Potency Independent of IFN and STING Signaling The Journal of Clinical Investigation. Mar, 2015 | Pubmed ID: 25642773 Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-naive Individuals The Journal of Infectious Diseases. Apr, 2015 | Pubmed ID: 25336730 A Human Vaccine Strategy Based on Chimpanzee Adenoviral and MVA Vectors That Primes, Boosts, and Sustains Functional HCV-specific T Cell Memory Science Translational Medicine. Nov, 2014 | Pubmed ID: 25378645 Dramatic Potentiation of the Antiviral Activity of HIV Antibodies by Cholesterol Conjugation The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25342747 Chimpanzee Adenovirus Vaccine Generates Acute and Durable Protective Immunity Against Ebolavirus Challenge Nature Medicine. Oct, 2014 | Pubmed ID: 25194571 Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2014 | Pubmed ID: 25156127 Role of Hypervariable Region 1 for the Interplay of Hepatitis C Virus with Entry Factors and Lipoproteins Journal of Virology. Nov, 2014 | Pubmed ID: 25142595 T-cell Immunity and Hepatitis C Virus Reinfection After Cure of Chronic Hepatitis C with an Interferon-free Antiviral Regimen in a Chimpanzee Hepatology (Baltimore, Md.). Nov, 2014 | Pubmed ID: 24975498 Enhanced Vaccine-induced CD8+ T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class Ii Invariant Chain PloS One. 2014 | Pubmed ID: 24945248 Production and Characterization of High-titer Serum-free Cell Culture Grown Hepatitis C Virus Particles of Genotype 1-6 Virology. Jun, 2014 | Pubmed ID: 24928051 Adenovirus Type 4 and 7 Vaccination or Adenovirus Type 4 Respiratory Infection Elicits Minimal Cross-reactive Antibody Responses to Nonhuman Adenovirus Vaccine Vectors Clinical and Vaccine Immunology : CVI. May, 2014 | Pubmed ID: 24623627 Combined Adenovirus Vector and Hepatitis C Virus Envelope Protein Prime-boost Regimen Elicits T Cell and Neutralizing Antibody Immune Responses Journal of Virology. May, 2014 | Pubmed ID: 24599994 Fusion of HCV Nonstructural Antigen to MHC Class II-associated Invariant Chain Enhances T-cell Responses Induced by Vectored Vaccines in Nonhuman Primates Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2014 | Pubmed ID: 24476798 Hypervariable Region 1 Deletion and Required Adaptive Envelope Mutations Confer Decreased Dependency on Scavenger Receptor Class B Type I and Low-density Lipoprotein Receptor for Hepatitis C Virus Journal of Virology. Feb, 2014 | Pubmed ID: 24257605 Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1 Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2014 | Pubmed ID: 24166483 Protective CD8+ T-cell Immunity to Human Malaria Induced by Chimpanzee Adenovirus-MVA Immunisation Nature Communications. 2013 | Pubmed ID: 24284865 Vaccination to Conserved Influenza Antigens in Mice Using a Novel Simian Adenovirus Vector, PanAd3, Derived from the Bonobo Pan Paniscus PloS One. 2013 | Pubmed ID: 23536756 Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-specific CD8+ T Cells Following Human-, Simian-, and Chimpanzee-derived Recombinant Adenoviral Vector Immunization Journal of Immunology (Baltimore, Md. : 1950). Mar, 2013 | Pubmed ID: 23390298 ChAd63-MVA-vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2012 | Pubmed ID: 23089736 Hepatitis C Virus-multispecific T-cell Responses Without Viremia or Seroconversion Among Egyptian Health Care Workers at High Risk of Infection Clinical and Vaccine Immunology : CVI. May, 2012 | Pubmed ID: 22441392 一种基于DNA/Ki67的流式细胞术测定法，用于接种疫苗的小鼠抗原特异性CD8 T细胞的细胞周期分析 Sonia Simonetti*1,2, Ambra Natalini*1,2, Giovanna Peruzzi3, Alfredo Nicosia4, Antonella Folgori5, Stefania Capone5, Angela Santoni2,6, Francesca Di Rosa1 1Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR), 2Department of Molecular Medicine, University of Rome “Sapienza”, 3Center for Life Nano Science, Istituto Italiano di Tecnologia, 4Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 5Reithera Srl, 6IRCCS, Neuromed JoVE 61867 Immunology and Infection
一种基于DNA/Ki67的流式细胞术测定法，用于接种疫苗的小鼠抗原特异性CD8 T细胞的细胞周期分析 Sonia Simonetti*1,2, Ambra Natalini*1,2, Giovanna Peruzzi3, Alfredo Nicosia4, Antonella Folgori5, Stefania Capone5, Angela Santoni2,6, Francesca Di Rosa1 1Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR), 2Department of Molecular Medicine, University of Rome “Sapienza”, 3Center for Life Nano Science, Istituto Italiano di Tecnologia, 4Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 5Reithera Srl, 6IRCCS, Neuromed JoVE 61867 Immunology and Infection
