Alvaro Rada-Iglesias Center for Molecular Medicine Cologne (CMMC) University of Cologne Biography Publications Institution JoVE Articles Alvaro Rada-Iglesias has not added a biography. If you are Alvaro Rada-Iglesias and would like to personalize this page please email our Author Liaison for assistance. Publications PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function During Pluripotent Stem Cell Differentiation Cell Stem Cell. May, 2017 | Pubmed ID: 28285903 Imputation of Orofacial Clefting Data Identifies Novel Risk Loci and Sheds Light on the Genetic Background of Cleft Lip ± Cleft Palate and Cleft Palate Only Human Molecular Genetics. Feb, 2017 | Pubmed ID: 28087736 GARLIC: a Bioinformatic Toolkit for Aetiologically Connecting Diseases and Cell Type-specific Regulatory Maps Human Molecular Genetics. Feb, 2017 | Pubmed ID: 28007912 Epigenomics-Based Identification of Major Cell Identity Regulators Within Heterogeneous Cell Populations Cell Reports. Dec, 2016 | Pubmed ID: 27974217 Foxd3 Promotes Exit from Naive Pluripotency Through Enhancer Decommissioning and Inhibits Germline Specification Cell Stem Cell. Jan, 2016 | Pubmed ID: 26748758 Genetic Variation Within Transcriptional Regulatory Elements and Its Implications for Human Disease Biological Chemistry. Dec, 2014 | Pubmed ID: 25205712 Human Genetic Variation Within Neural Crest Enhancers: Molecular and Phenotypic Implications Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 2013 | Pubmed ID: 23650634 Pioneering Barren Land: Mitotic Bookmarking by Transcription Factors Developmental Cell. Feb, 2013 | Pubmed ID: 23449470 Epigenomic Annotation of Enhancers Predicts Transcriptional Regulators of Human Neural Crest Cell Stem Cell. Nov, 2012 | Pubmed ID: 22981823 The Homeodomain-leucine Zipper (HD-Zip) Class I Transcription Factors ATHB7 and ATHB12 Modulate Abscisic Acid Signalling by Regulating Protein Phosphatase 2C and Abscisic Acid Receptor Gene Activities Plant Molecular Biology. Nov, 2012 | Pubmed ID: 22968620 Epigenomics of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells: Insights into Pluripotency and Implications for Disease Genome Medicine. Jun, 2011 | Pubmed ID: 21658297 Sequence-specific Regulator Prdm14 Safeguards Mouse ESCs from Entering Extraembryonic Endoderm Fates Nature Structural & Molecular Biology. Feb, 2011 | Pubmed ID: 21183938 A Unique Chromatin Signature Uncovers Early Developmental Enhancers in Humans Nature. Feb, 2011 | Pubmed ID: 21160473 Integrative Epigenomic and Genomic Analysis of Malignant Pheochromocytoma Experimental & Molecular Medicine. Jul, 2010 | Pubmed ID: 20534969 CHD7 Cooperates with PBAF to Control Multipotent Neural Crest Formation Nature. Feb, 2010 | Pubmed ID: 20130577 Two Polypyrimidine Tracts in the Nitric Oxide Synthase 2 Gene: Similar Regulatory Sequences with Different Properties Molecular Biology Reports. Apr, 2010 | Pubmed ID: 19669598 Nucleosomes Are Well Positioned in Exons and Carry Characteristic Histone Modifications Genome Research. Oct, 2009 | Pubmed ID: 19687145 Identification of Candidate Regulatory SNPs by Combination of Transcription-factor-binding Site Prediction, SNP Genotyping and HaploChIP Nucleic Acids Research. Jul, 2009 | Pubmed ID: 19451166 Histone H3 Lysine 27 Trimethylation in Adult Differentiated Colon Associated to Cancer DNA Hypermethylation Epigenetics. Feb, 2009 | Pubmed ID: 19276669 Histone Acetylation and Methylation at Sites Initiating Divergent Polycistronic Transcription in Trypanosoma Cruzi The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18400752 Whole-genome Maps of USF1 and USF2 Binding and Histone H3 Acetylation Reveal New Aspects of Promoter Structure and Candidate Genes for Common Human Disorders Genome Research. Mar, 2008 | Pubmed ID: 18230803 Monte Carlo Feature Selection for Supervised Classification Bioinformatics (Oxford, England). Jan, 2008 | Pubmed ID: 18048398 Identification and Analysis of Functional Elements in 1% of the Human Genome by the ENCODE Pilot Project Nature. Jun, 2007 | Pubmed ID: 17571346 Butyrate Mediates Decrease of Histone Acetylation Centered on Transcription Start Sites and Down-regulation of Associated Genes Genome Research. Jun, 2007 | Pubmed ID: 17567991 In Vitro Analysis of DNA-protein Interactions by Proximity Ligation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17360610 The Promoter of Inducible Nitric Oxide Synthase Implicated in Glaucoma Based on Genetic Analysis and Nuclear Factor Binding Molecular Vision. Nov, 2005 | Pubmed ID: 16288199 Binding Sites for Metabolic Disease Related Transcription Factors Inferred at Base Pair Resolution by Chromatin Immunoprecipitation and Genomic Microarrays Human Molecular Genetics. Nov, 2005 | Pubmed ID: 16221759 Some Microsatellites May Act As Novel Polymorphic Cis-regulatory Elements Through Transcription Factor Binding Gene. Oct, 2004 | Pubmed ID: 15474298 Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples Rizwan Rehimi1, Michaela Bartusel1, Francesca Solinas2, Janine Altmüller2, Alvaro Rada-Iglesias1,3 1Center for Molecular Medicine Cologne (CMMC), University of Cologne, 2Cologne Center for Genomics (CCG), University of Cologne, 3Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), Research Center and Systems Biology of Ageing Cologne, University of Cologne JoVE 56186 Genetics
Chromatin Immunoprecipitation (ChIP) Protocol for Low-abundance Embryonic Samples Rizwan Rehimi1, Michaela Bartusel1, Francesca Solinas2, Janine Altmüller2, Alvaro Rada-Iglesias1,3 1Center for Molecular Medicine Cologne (CMMC), University of Cologne, 2Cologne Center for Genomics (CCG), University of Cologne, 3Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), Research Center and Systems Biology of Ageing Cologne, University of Cologne JoVE 56186 Genetics
