Andrew J. H. Smith MRC Centre for Regenerative Medicine University of Edinburgh Biography Publications Institution JoVE Articles Andrew J. H. Smith has not added a biography. If you are Andrew J. H. Smith and would like to personalize this page please email our Author Liaison for assistance. Publications Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells Stem Cell Reports. 06, 2018 | Pubmed ID: 29779895 A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1 Developmental Cell. 02, 2018 | Pubmed ID: 29290585 DNA Methylation of Intragenic CpG Islands Depends on Their Transcriptional Activity During Differentiation and Disease Proceedings of the National Academy of Sciences of the United States of America. 09, 2017 | Pubmed ID: 28827334 Intrinsic Factors and the Embryonic Environment Influence the Formation of Extragonadal Teratomas During Gestation BMC Developmental Biology. 2015 | Pubmed ID: 26453549 Hes1 Desynchronizes Differentiation of Pluripotent Cells by Modulating STAT3 Activity Stem Cells (Dayton, Ohio). Aug, 2013 | Pubmed ID: 23649667 Tcf15 Primes Pluripotent Cells for Differentiation Cell Reports. Feb, 2013 | Pubmed ID: 23395635 Transposon-mediated BAC Transgenesis in Human ES Cells Nucleic Acids Research. Oct, 2012 | Pubmed ID: 22753106 Genomically Humanized Mice: Technologies and Promises Nature Reviews. Genetics. Dec, 2011 | Pubmed ID: 22179716 Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells but is Dispensable for Medullary Sublineage Divergence PLoS Genetics. Nov, 2011 | Pubmed ID: 22072979 An Interspecies Analysis Reveals a Key Role for Unmethylated CpG Dinucleotides in Vertebrate Polycomb Complex Recruitment The EMBO Journal. 2011 | Pubmed ID: 22056776 Polycomb Eviction As a New Distant Enhancer Function Genes & Development. Aug, 2011 | Pubmed ID: 21828268 Dominant Role of the P110beta Isoform of PI3K over P110alpha in Energy Homeostasis Regulation by POMC and AgRP Neurons Cell Metabolism. Nov, 2009 | Pubmed ID: 19883613 Association Between Active Genes Occurs at Nuclear Speckles and is Modulated by Chromatin Environment The Journal of Cell Biology. Sep, 2008 | Pubmed ID: 18809724 The P110beta Isoform of Phosphoinositide 3-kinase Signals Downstream of G Protein-coupled Receptors and is Functionally Redundant with P110gamma Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18544649 Control of Axonal Growth and Regeneration of Sensory Neurons by the P110delta PI 3-kinase PloS One. Sep, 2007 | Pubmed ID: 17846664 Experimental Acute Pancreatitis in PAP/HIP Knock-out Mice Gut. Aug, 2007 | Pubmed ID: 17409121 Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence Cell. Jan, 2007 | Pubmed ID: 17218265 Loss of Atrx Affects Trophoblast Development and the Pattern of X-inactivation in Extraembryonic Tissues PLoS Genetics. Apr, 2006 | Pubmed ID: 16628246 Neurofascins Are Required to Establish Axonal Domains for Saltatory Conduction Neuron. Dec, 2005 | Pubmed ID: 16337912 Expression of Butyrophilin (Btn1a1) in Lactating Mammary Gland is Essential for the Regulated Secretion of Milk-lipid Droplets Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15226505 Essential Role for Proteinase-activated Receptor-2 in Arthritis The Journal of Clinical Investigation. Jan, 2003 | Pubmed ID: 12511586 Cre-loxP Chromosome Engineering of a Targeted Deletion in the Mouse Corresponding to the 3p21.3 Region of Homozygous Loss in Human Tumours Oncogene. Jul, 2002 | Pubmed ID: 12085230 Role of Beta-dystrobrevin in Nonmuscle Dystrophin-associated Protein Complex-like Complexes in Kidney and Liver Molecular and Cellular Biology. Nov, 2001 | Pubmed ID: 11585924 Multiomics Analyses of HNF4α Protein Domain Function During Human Pluripotent Stem Cell Differentiation IScience. | Pubmed ID: 31185456 Vi introduserer punktmutasjoner i menneskelige pluripotente stamceller ved hjelp av sømløs genomredigering Yu Wang1, Andrew J. H. Smith1, David C. Hay1 1MRC Centre for Regenerative Medicine, University of Edinburgh JoVE 61152 Genetics
Vi introduserer punktmutasjoner i menneskelige pluripotente stamceller ved hjelp av sømløs genomredigering Yu Wang1, Andrew J. H. Smith1, David C. Hay1 1MRC Centre for Regenerative Medicine, University of Edinburgh JoVE 61152 Genetics