Antonis K. Hatzopoulos

Publications

• Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension
  Hypertension. Feb, 2016  |   Pubmed ID: 26693821
• Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis
  Circulation Research. Oct, 2015  |   Pubmed ID: 26338900
• Endothelial Cells Contribute to Generation of Adult Ventricular Myocytes During Cardiac Homeostasis
  Cell Reports. Jul, 2014  |   Pubmed ID: 25001281
• Endothelial Progenitor Cells Augment Collateralization and Hemodynamic Rescue in a Model of Chronic Cerebral Ischemia
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2014  |   Pubmed ID: 24780900
• Gremlin 2 Promotes Differentiation of Embryonic Stem Cells to Atrial Fate by Activation of the JNK Signaling Pathway
  Stem Cells (Dayton, Ohio). Jul, 2014  |   Pubmed ID: 24648383
• SDF-1 Fused to a Fractalkine Stalk and a GPI Anchor Enables Functional Neovascularization
  Stem Cells (Dayton, Ohio). Sep, 2013  |   Pubmed ID: 23744498
• Functional Modeling in Zebrafish Demonstrates That the Atrial-fibrillation-associated Gene GREM2 Regulates Cardiac Laterality, Cardiomyocyte Differentiation and Atrial Rhythm
  Disease Models & Mechanisms. Mar, 2013  |   Pubmed ID: 23223679
• Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: the TIME Randomized Trial
  JAMA : the Journal of the American Medical Association. Dec, 2012  |   Pubmed ID: 23129008
• Egr-1 Induces DARPP-32 Expression in Striatal Medium Spiny Neurons Via a Conserved Intragenic Element
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2012  |   Pubmed ID: 22593050
• Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure: The FOCUS-CCTRN Trial
  JAMA : the Journal of the American Medical Association. Mar, 2012  |   Pubmed ID: 22447880
• Continuous Antagonism by Dkk1 Counter Activates Canonical Wnt Signaling and Promotes Cardiomyocyte Differentiation of Embryonic Stem Cells
  Stem Cells and Development. Jan, 2012  |   Pubmed ID: 21861760
• Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis
  Recent Patents on Regenerative Medicine. Sep, 2011  |   Pubmed ID: 22787575
• Combinatorial Polymer Electrospun Matrices Promote Physiologically-relevant Cardiomyogenic Stem Cell Differentiation
  PloS One. 2011  |   Pubmed ID: 22216144
• Discovering Small Molecules That Promote Cardiomyocyte Generation by Modulating Wnt Signaling
  Chemistry & Biology. Dec, 2011  |   Pubmed ID: 22195568
• Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: the LateTIME Randomized Trial
  JAMA : the Journal of the American Medical Association. Nov, 2011  |   Pubmed ID: 22084195
• Programmatic Change: Lung Disease Research in the Era of Induced Pluripotency
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2011  |   Pubmed ID: 21984571
• Tfap2a and Foxd3 Regulate Early Steps in the Development of the Neural Crest Progenitor Population
  Developmental Biology. Dec, 2011  |   Pubmed ID: 21963426
• The Feelgood Mutation in Zebrafish Dysregulates COPII-dependent Secretion of Select Extracellular Matrix Proteins in Skeletal Morphogenesis
  Disease Models & Mechanisms. Nov, 2011  |   Pubmed ID: 21729877
• Preconditioned Endothelial Progenitor Cells Reduce Formation of Melanoma Metastases Through SPARC-driven Cell-cell Interactions and Endocytosis
  Cancer Research. Jul, 2011  |   Pubmed ID: 21616936
• Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation
  Circulation Research. Jul, 2011  |   Pubmed ID: 21597012
• Experimental Myocardial Infarction Triggers Canonical Wnt Signaling and Endothelial-to-mesenchymal Transition
  Disease Models & Mechanisms. Jul, 2011  |   Pubmed ID: 21324930
• Neuregulin-1β Regulation of Embryonic Endothelial Progenitor Cell Survival
  American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2011  |   Pubmed ID: 21239627
• Role of Guanylate Binding Protein-1 in Vascular Defects Associated with Chronic Inflammatory Diseases
  Journal of Cellular and Molecular Medicine. Jul, 2011  |   Pubmed ID: 20716116
• Time is Like a Clock in My Heart: Implications for Stem Cell Delivery After Myocardial Infarction
  Cardiology. 2010  |   Pubmed ID: 21042016
• LateTIME: a Phase-II, Randomized, Double-blinded, Placebo-controlled, Pilot Trial Evaluating the Safety and Effect of Administration of Bone Marrow Mononuclear Cells 2 to 3 Weeks After Acute Myocardial Infarction
  Texas Heart Institute Journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 2010  |   Pubmed ID: 20844613
• Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells for Patients with Chronic Ischemic Heart Disease and Left Ventricular Dysfunction (First Mononuclear Cells Injected in the US [FOCUS]): Rationale and Design
  American Heart Journal. Aug, 2010  |   Pubmed ID: 20691824
• Thymosin Beta4: a Key Factor for Protective Effects of EEPCs in Acute and Chronic Ischemia
  Annals of the New York Academy of Sciences. Apr, 2010  |   Pubmed ID: 20536456
• Adriamycin Nephropathy: a Failure of Endothelial Progenitor Cell-induced Repair
  The American Journal of Pathology. Apr, 2010  |   Pubmed ID: 20167859
• Stem Cell Therapy: Pieces of the Puzzle
  Journal of Cardiovascular Translational Research. Feb, 2010  |   Pubmed ID: 20119487
• NF KappaB Activation in Embryonic Endothelial Progenitor Cells Enhances Neovascularization Via PSGL-1 Mediated Recruitment: Novel Role for LL37
  Stem Cells (Dayton, Ohio). Feb, 2010  |   Pubmed ID: 20014279
• The FunGenES Database: a Genomics Resource for Mouse Embryonic Stem Cell Differentiation
  PloS One. 2009  |   Pubmed ID: 19727443
• Rationale and Design for TIME: A Phase II, Randomized, Double-blind, Placebo-controlled Pilot Trial Evaluating the Safety and Effect of Timing of Administration of Bone Marrow Mononuclear Cells After Acute Myocardial Infarction
  American Heart Journal. Sep, 2009  |   Pubmed ID: 19699857
• Stem Cell Therapy for Cardiac Repair: Benefits and Barriers
  Expert Reviews in Molecular Medicine. 2009  |   Pubmed ID: 19586557
• Cardiac Repair and Regeneration: the Rubik's Cube of Cell Therapy for Heart Disease
  Disease Models & Mechanisms. Jul-Aug, 2009  |   Pubmed ID: 19553696
• T17b Murine Embryonal Endothelial Progenitor Cells Can Be Induced Towards Both Proliferation and Differentiation in a Fibrin Matrix
  Journal of Cellular and Molecular Medicine. May, 2009  |   Pubmed ID: 19538255
• Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells
  PloS One. 2008  |   Pubmed ID: 18682835
• Egr-1 Regulates Expression of the Glial Scar Component Phosphacan in Astrocytes After Experimental Stroke
  The American Journal of Pathology. Jul, 2008  |   Pubmed ID: 18556777
• Thymosin Beta4 is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell-mediated Cardioprotection
  Circulation. Apr, 2008  |   Pubmed ID: 18427126
• B-Raf-mediated Signaling Pathway Regulates T Cell Development
  European Journal of Immunology. Feb, 2008  |   Pubmed ID: 18228248
• Adenosine Receptor-mediated Adhesion of Endothelial Progenitors to Cardiac Microvascular Endothelial Cells
  Circulation Research. Feb, 2008  |   Pubmed ID: 18032734
• Rafs Constitute a Nodal Point in the Regulation of Embryonic Endothelial Progenitor Cell Growth and Differentiation
  Journal of Cellular and Molecular Medicine. Nov-Dec, 2007  |   Pubmed ID: 18205709
• Biologic Properties of Endothelial Progenitor Cells and Their Potential for Cell Therapy
  Progress in Cardiovascular Diseases. May-Jun, 2007  |   Pubmed ID: 17498522
• Platelet-induced Differentiation of Endothelial Progenitor Cells
  Seminars in Thrombosis and Hemostasis. Mar, 2007  |   Pubmed ID: 17340461
• Hypoxia-mediated Activation of Dll4-Notch-Hey2 Signaling in Endothelial Progenitor Cells and Adoption of Arterial Cell Fate
  Experimental Cell Research. Jan, 2007  |   Pubmed ID: 17045587
• The Mother Superior Mutation Ablates Foxd3 Activity in Neural Crest Progenitor Cells and Depletes Neural Crest Derivatives in Zebrafish
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2006  |   Pubmed ID: 17013879
• Expression of the Protein Related to Dan and Cerberus Gene--prdc--During Eye, Pharyngeal Arch, Somite, and Swim Bladder Development in Zebrafish
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2006  |   Pubmed ID: 16921498
• Coordinated Changes of Histone Modifications and HDAC Mobilization Regulate the Induction of MHC Class II Genes by Trichostatin A
  Nucleic Acids Research. 2006  |   Pubmed ID: 16452299
• Adherent Platelets Recruit and Induce Differentiation of Murine Embryonic Endothelial Progenitor Cells to Mature Endothelial Cells in Vitro
  Circulation Research. Feb, 2006  |   Pubmed ID: 16373597
• Retroinfusion of Embryonic Endothelial Progenitor Cells Attenuates Ischemia-reperfusion Injury in Pigs: Role of Phosphatidylinositol 3-kinase/AKT Kinase
  Circulation. Aug, 2005  |   Pubmed ID: 16159802
• Embryonic Endothelial Progenitor Cells Expressing a Broad Range of Proangiogenic and Remodeling Factors Enhance Vascularization and Tissue Recovery in Acute and Chronic Ischemia
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2005  |   Pubmed ID: 16009705
• Cytoplasmic Thioredoxin Reductase is Essential for Embryogenesis but Dispensable for Cardiac Development
  Molecular and Cellular Biology. Mar, 2005  |   Pubmed ID: 15713651
• Essential Role for Mitochondrial Thioredoxin Reductase in Hematopoiesis, Heart Development, and Heart Function
  Molecular and Cellular Biology. Nov, 2004  |   Pubmed ID: 15485910
• Embryonic Endothelial Progenitor Cells Armed with a Suicide Gene Target Hypoxic Lung Metastases After Intravenous Delivery
  Cancer Cell. May, 2004  |   Pubmed ID: 15144955
• Multistep Nature of Microvascular Recruitment of Ex Vivo-expanded Embryonic Endothelial Progenitor Cells During Tumor Angiogenesis
  The Journal of Experimental Medicine. Jun, 2003  |   Pubmed ID: 12810693
• Participation of Bone Marrow-derived Cells in Long-term Repair Processes After Experimental Stroke
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2003  |   Pubmed ID: 12796719