Arun Srivastava Department of Pediatrics, Division of Cellular and Molecular Therapy University of Florida Biography Publications Institution JoVE Articles Arun Srivastava has not added a biography. If you are Arun Srivastava and would like to personalize this page please email our Author Liaison for assistance. Publications Role of Molecular Genetics in Hemophilia: from Diagnosis to Therapy Seminars in Thrombosis and Hemostasis. Feb, 2012 | Pubmed ID: 22314605 A Simplified Immune Suppression Scheme Leads to Persistent Micro-dystrophin Expression in Duchenne Muscular Dystrophy Dogs Human Gene Therapy. Feb, 2012 | Pubmed ID: 21967249 Giant Primary Intraosseous Calvarial Hemangioma of the Occipital Bone Neurology India. Sep-Oct, 2011 | Pubmed ID: 22019676 Innate Immune Responses to AAV Vectors Frontiers in Microbiology. 2011 | Pubmed ID: 21954398 Size Distribution and Source Apportionment of Polycyclic Aromatic Hydrocarbons (PAHs) in Aerosol Particle Samples from the Atmospheric Environment of Delhi, India The Science of the Total Environment. Oct, 2011 | Pubmed ID: 21889785 Primary Melanocytic Tumors of the Central Nervous System: a Neuroradiological and Clinicopathological Study of Five Cases and Brief Review of Literature Neurology India. May-Jun, 2011 | Pubmed ID: 21743173 A Clinicopathological and Neuroradiological Study of Paediatric Meningioma from a Single Centre Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Aug, 2011 | Pubmed ID: 21719288 Cellular Fusion for Gene Delivery to SCA1 Affected Purkinje Neurons Molecular and Cellular Neurosciences. May, 2011 | Pubmed ID: 21420496 Activation of the NF-kappaB Pathway by Adeno-associated Virus (AAV) Vectors and Its Implications in Immune Response and Gene Therapy Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21321191 Cytomorphology of Giant Cell Glioblastoma: Report of a Case and Brief Review of Literature Diagnostic Cytopathology. Feb, 2011 | Pubmed ID: 21319330 A Simple Method to Increase the Transduction Efficiency of Single-stranded Adeno-associated Virus Vectors in Vitro and in Vivo Human Gene Therapy. May, 2011 | Pubmed ID: 21219084 Recombinant Adeno-associated Virus-mediated Gene Transfer for the Potential Therapy of Adenosine Deaminase-deficient Severe Combined Immune Deficiency Human Gene Therapy. Aug, 2011 | Pubmed ID: 21142972 Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2011 | Pubmed ID: 21045809 A Clinicopathological, Immunohistochemical and Neuroradiological Study of Eight Patients with Central Neurocytoma Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Mar, 2011 | Pubmed ID: 20869874 Association of Matrix Metalloproteinase-1 Gene Polymorphism with Glioblastoma Multiforme in a Northern Indian Population Journal of Neuro-oncology. May, 2011 | Pubmed ID: 20706772 Spinal Epidural Lipomatosis: An Unusual Cause of Relapsing and Remitting Paraparesis Journal of Pediatric Neurosciences. Jul, 2010 | Pubmed ID: 21559166 Squash Cytology of Subependymal Giant Cell Astrocytoma: Report of Four Cases with Brief Review of Literature Diagnostic Cytopathology. Nov, 2010 | Pubmed ID: 21080451 Common Primary Fibroblastic Growth Factor Receptor-related Craniosynostosis Syndromes: A Pictorial Review Journal of Pediatric Neurosciences. Jan, 2010 | Pubmed ID: 21042516 Sacrococcygeal Teratoma Journal of Pediatric Neurosciences. Jan, 2010 | Pubmed ID: 21042504 Os Odontoideum with "free-floating" Atlantal Arch Causing C1-2 Anterolisthesis and Retrolisthesis with Cervicomedullary Compression Indian Journal of Orthopaedics. Oct, 2010 | Pubmed ID: 20924483 High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2010 | Pubmed ID: 20736929 An Animal Model of PDH Deficiency Using AAV8-siRNA Vector-mediated Knockdown of Pyruvate Dehydrogenase E1α Molecular Genetics and Metabolism. Oct-Nov, 2010 | Pubmed ID: 20685142 Human Hepatocyte Growth Factor Receptor is a Cellular Coreceptor for Adeno-associated Virus Serotype 3 Human Gene Therapy. Dec, 2010 | Pubmed ID: 20545554 High-efficiency Transduction of Fibroblasts and Mesenchymal Stem Cells by Tyrosine-mutant AAV2 Vectors for Their Potential Use in Cellular Therapy Human Gene Therapy. Nov, 2010 | Pubmed ID: 20507237 Adeno-associated Virus Serotype 6 Capsid Tyrosine-to-phenylalanine Mutations Improve Gene Transfer to Skeletal Muscle Human Gene Therapy. Oct, 2010 | Pubmed ID: 20497037 Enhanced Long-term Transduction and Multilineage Engraftment of Human Hematopoietic Stem Cells Transduced with Tyrosine-modified Recombinant Adeno-associated Virus Serotype 2 Human Gene Therapy. Sep, 2010 | Pubmed ID: 20486772 Two Decades of Clinical Gene Therapy--success is Finally Mounting Discovery Medicine. Feb, 2010 | Pubmed ID: 20193635 Optimized Adeno-associated Virus (AAV)-protein Phosphatase-5 Helper Viruses for Efficient Liver Transduction by Single-stranded AAV Vectors: Therapeutic Expression of Factor IX at Reduced Vector Doses Human Gene Therapy. Mar, 2010 | Pubmed ID: 19788390 AAV3-mediated Transfer and Expression of the Pyruvate Dehydrogenase E1 Alpha Subunit Gene Causes Metabolic Remodeling and Apoptosis of Human Liver Cancer Cells Molecular Genetics and Metabolism. Nov, 2009 | Pubmed ID: 19586787 Calpeptin Increases the Activity of Upstream Stimulatory Factor and Induces High Level Globin Gene Expression in Erythroid Cells The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19491096 High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2009 | Pubmed ID: 19066593 SEM-EDX Analysis of Various Sizes Aerosols in Delhi India Environmental Monitoring and Assessment. Mar, 2009 | Pubmed ID: 18386148 Tyrosine-phosphorylation of AAV2 Vectors and Its Consequences on Viral Intracellular Trafficking and Transgene Expression Virology. Nov, 2008 | Pubmed ID: 18834608 Pilomatricoma Mimicking Small Round Cell Tumor on Fine Needle Aspiration Cytology: a Case Report Acta Cytologica. Sep-Oct, 2008 | Pubmed ID: 18833830 Working Group Report: the Roles of Glycans in Hemostasis, Inflammation and Vascular Biology Glycobiology. Oct, 2008 | Pubmed ID: 18621991 Next Generation of Adeno-associated Virus 2 Vectors: Point Mutations in Tyrosines Lead to High-efficiency Transduction at Lower Doses Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18511559 Adeno-associated Virus-mediated Gene Transfer Journal of Cellular Biochemistry. Sep, 2008 | Pubmed ID: 18500727 Optimization of Recombinant Adeno-associated Viral Vectors for Human Beta-globin Gene Transfer and Transgene Expression Human Gene Therapy. Apr, 2008 | Pubmed ID: 18399730 Recombinant Self-complementary Adeno-associated Virus Serotype Vector-mediated Hematopoietic Stem Cell Transduction and Lineage-restricted, Long-term Transgene Expression in a Murine Serial Bone Marrow Transplantation Model Human Gene Therapy. Apr, 2008 | Pubmed ID: 18370591 Stable Integration of Recombinant Adeno-associated Virus Vector Genomes After Transduction of Murine Hematopoietic Stem Cells Human Gene Therapy. Mar, 2008 | Pubmed ID: 18303957 A Combined Therapeutic Approach for Pyruvate Dehydrogenase Deficiency Using Self-complementary Adeno-associated Virus Serotype-specific Vectors and Dichloroacetate Molecular Genetics and Metabolism. Apr, 2008 | Pubmed ID: 18206410 Single-polarity Recombinant Adeno-associated Virus 2 Vector-mediated Transgene Expression in Vitro and in Vivo: Mechanism of Transduction Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2008 | Pubmed ID: 18087261 Particle Size Distribution of Aerosols and Associated Heavy Metals in Kitchen Environments Environmental Monitoring and Assessment. Jul, 2008 | Pubmed ID: 17963046 Pyruvate Dehydrogenase Complex Deficiency Caused by Ubiquitination and Proteasome-mediated Degradation of the E1 Subunit The Journal of Biological Chemistry. Jan, 2008 | Pubmed ID: 17923481 A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2007 | Pubmed ID: 17440440 Down-regulation of Expression of Rat Pyruvate Dehydrogenase E1alpha Gene by Self-complementary Adeno-associated Virus-mediated Small Interfering RNA Delivery Mitochondrion. Jul, 2007 | Pubmed ID: 17392036 Self-complementary Recombinant Adeno-associated Viral Vectors: Packaging Capacity and the Role of Rep Proteins in Vector Purity Human Gene Therapy. Feb, 2007 | Pubmed ID: 17328683 Size Distribution and Source Identification of Total Suspended Particulate Matter and Associated Heavy Metals in the Urban Atmosphere of Delhi Chemosphere. Jun, 2007 | Pubmed ID: 17275883 Seasonal Trends in Coarse and Fine Particle Sources in Delhi by the Chemical Mass Balance Receptor Model Journal of Hazardous Materials. Jun, 2007 | Pubmed ID: 17110024 Adeno-associated Virus-mediated Gene Transfer in Hematopoietic Stem/ Progenitor Cells As a Therapeutic Tool Current Gene Therapy. Dec, 2006 | Pubmed ID: 17168699 Role of Integrin Cross-regulation in Parvovirus B19 Targeting Human Gene Therapy. Sep, 2006 | Pubmed ID: 16972759 FK506-binding Protein 52 is Essential to Uterine Reproductive Physiology Controlled by the Progesterone Receptor A Isoform Molecular Endocrinology (Baltimore, Md.). Nov, 2006 | Pubmed ID: 16873445 Role of Cellular FKBP52 Protein in Intracellular Trafficking of Recombinant Adeno-associated Virus 2 Vectors Virology. Sep, 2006 | Pubmed ID: 16828834 Evaluation of Primitive Murine Hematopoietic Stem and Progenitor Cell Transduction in Vitro and in Vivo by Recombinant Adeno-associated Virus Vector Serotypes 1 Through 5 Human Gene Therapy. Mar, 2006 | Pubmed ID: 16544981 A Study to Characterize the Influence of Outdoor SPM and Associated Metals on Indoor Environment in Delhi Journal of Environmental Science & Engineering. Jul, 2005 | Pubmed ID: 16841462 Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors: Problems and Solutions Human Gene Therapy. Jul, 2005 | Pubmed ID: 16000061 Impaired Nuclear Transport and Uncoating Limit Recombinant Adeno-associated Virus 2 Vector-mediated Transduction of Primary Murine Hematopoietic Cells Human Gene Therapy. Dec, 2004 | Pubmed ID: 15684697 Self-complementary Adeno-associated Virus 2 (AAV)-T Cell Protein Tyrosine Phosphatase Vectors As Helper Viruses to Improve Transduction Efficiency of Conventional Single-stranded AAV Vectors in Vitro and in Vivo Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2004 | Pubmed ID: 15509512 Gene Delivery to Human and Murine Primitive Hematopoietic Stem and Progenitor Cells by AAV2 Vectors Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14970598 Heat-shock Treatment-mediated Increase in Transduction by Recombinant Adeno-associated Virus 2 Vectors is Independent of the Cellular Heat-shock Protein 90 The Journal of Biological Chemistry. Mar, 2004 | Pubmed ID: 14711833 Alpha5beta1 Integrin As a Cellular Coreceptor for Human Parvovirus B19: Requirement of Functional Activation of Beta1 Integrin for Viral Entry Blood. Dec, 2003 | Pubmed ID: 12907437 Adeno-associated Virus Type 2-mediated Gene Transfer: Role of Cellular T-cell Protein Tyrosine Phosphatase in Transgene Expression in Established Cell Lines in Vitro and Transgenic Mice in Vivo Journal of Virology. Feb, 2003 | Pubmed ID: 12552015 Recombinant Human Parvovirus B19 Vectors Pathologie-biologie. Jun, 2002 | Pubmed ID: 12116848 Obstacles to Human Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus 2 Vectors Journal of Cellular Biochemistry. Supplement. 2002 | Pubmed ID: 12046848 Высокоэффективные трансдукция клеток рака печени с помощью рекомбинантной адено-ассоциированные вирус серотипа 3 Вектора Chen Ling1, Yuan Lu1, Binbin Cheng1, Katherine E. McGoogan1, Samantha W.Y. Gee1, Wenqin Ma1, Baozheng Li1, George V. Aslanidi1, Arun Srivastava1 1Department of Pediatrics, Division of Cellular and Molecular Therapy, University of Florida JoVE 2538 Medicine
Высокоэффективные трансдукция клеток рака печени с помощью рекомбинантной адено-ассоциированные вирус серотипа 3 Вектора Chen Ling1, Yuan Lu1, Binbin Cheng1, Katherine E. McGoogan1, Samantha W.Y. Gee1, Wenqin Ma1, Baozheng Li1, George V. Aslanidi1, Arun Srivastava1 1Department of Pediatrics, Division of Cellular and Molecular Therapy, University of Florida JoVE 2538 Medicine