Beilei Lei Multidisciplinary Neuroprotection Laboratories, Department of Anesthesiology Duke University Biography Publications Institution JoVE Articles Beilei Lei has not added a biography. If you are Beilei Lei and would like to personalize this page please email our Author Liaison for assistance. Publications Stimulation of α1a Adrenergic Receptors Induces Cellular Proliferation or Antiproliferative Hypertrophy Dependent Solely on Agonist Concentration PloS One. 2013 | Pubmed ID: 23991110 Tumor Necrosis Factor α Antagonism Improves Neurological Recovery in Murine Intracerebral Hemorrhage Journal of Neuroinflammation. 2013 | Pubmed ID: 23962089 Interaction Between Sex and Apolipoprotein E Genetic Background in a Murine Model of Intracerebral Hemorrhage Translational Stroke Research. Mar, 2012 | Pubmed ID: 23935764 Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage Anesthesiology. Dec, 2012 | Pubmed ID: 23143806 Activity-based Near-infrared Fluorescent Probe for LMP7: a Chemical Proteomics Tool for the Immunoproteasome in Living Cells Chembiochem : a European Journal of Chemical Biology. Sep, 2012 | Pubmed ID: 22807337 Fundamental Reaction Pathway and Free Energy Profile for Inhibition of Proteasome by Epoxomicin Journal of the American Chemical Society. Jun, 2012 | Pubmed ID: 22697787 TT-301 Inhibits Microglial Activation and Improves Outcome After Central Nervous System Injury in Adult Mice Anesthesiology. Jun, 2012 | Pubmed ID: 22487803 Statins Improve Outcome in Murine Models of Intracranial Hemorrhage and Traumatic Brain Injury: A Translational Approach Journal of Neurotrauma. Jan, 2012 | Pubmed ID: 22233347 The ApoE-mimetic Peptide, COG1410, Improves Functional Recovery in a Murine Model of Intracerebral Hemorrhage Neurocritical Care. Apr, 2012 | Pubmed ID: 21989844 A Bright Approach to the Immunoproteasome: Development of LMP2/β1i-specific Imaging Probes Bioorganic & Medicinal Chemistry. Jan, 2012 | Pubmed ID: 21741845 In Silico Prediction of Deleterious Single Amino Acid Polymorphisms from Amino Acid Sequence Journal of Computational Chemistry. May, 2011 | Pubmed ID: 21425278 Structural Requirements of Isoquinolones As Novel Selective C-Jun N-terminal Kinase 1 Inhibitors: 2D and 3D QSAR Analyses Chemical Biology & Drug Design. Apr, 2011 | Pubmed ID: 21276204 Structure-based Quantitative Structure-activity Relationship Studies of Checkpoint Kinase 1 Inhibitors Journal of Computational Chemistry. Nov, 2010 | Pubmed ID: 20839304 Molecular Basis of the Selectivity of the Immunoproteasome Catalytic Subunit LMP2-specific Inhibitor Revealed by Molecular Modeling and Dynamics Simulations The Journal of Physical Chemistry. B. Sep, 2010 | Pubmed ID: 20812720 Global and Local Prediction of Protein Folding Rates Based on Sequence Autocorrelation Information Journal of Theoretical Biology. Jun, 2010 | Pubmed ID: 20362588 Molecular Modeling Studies of Rho Kinase Inhibitors Using Molecular Docking and 3D-QSAR Analysis European Journal of Medicinal Chemistry. Jul, 2010 | Pubmed ID: 20347188 A New Strategy to Improve the Predictive Ability of the Local Lazy Regression and Its Application to the QSAR Study of Melanin-concentrating Hormone Receptor 1 Antagonists Journal of Computational Chemistry. Apr, 2010 | Pubmed ID: 19670228 Rational Prediction of the Herbicidal Activities of Novel Protoporphyrinogen Oxidase Inhibitors by Quantitative Structure-activity Relationship Model Based on Docking-guided Active Conformation Journal of Agricultural and Food Chemistry. Oct, 2009 | Pubmed ID: 19780536 Lipid Rafts Constrain Basal Alpha(1A)-adrenergic Receptor Signaling by Maintaining Receptor in an Inactive Conformation Cellular Signalling. Oct, 2009 | Pubmed ID: 19520158 Global, Local and Novel Consensus Quantitative Structure-activity Relationship Studies of 4-(Phenylaminomethylene) Isoquinoline-1, 3 (2H, 4H)-diones As Potent Inhibitors of the Cyclin-dependent Kinase 4 Analytica Chimica Acta. Jun, 2009 | Pubmed ID: 19463556 Specific Interaction of 4'-O-(a-l-Cladinosyl) Daunorubicin with Human Serum Albumin: The Binding Site II on HSA Molecular Using Spectroscopy and Modeling Journal of Photochemistry and Photobiology. B, Biology. Jun, 2009 | Pubmed ID: 19345112 Novel Approaches for Retention Time Prediction of Oligonucleotides in Ion-pair Reversed-phase High-performance Liquid Chromatography Journal of Chromatography. A. May, 2009 | Pubmed ID: 19324364 Molecular Modeling Studies of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors Using QSAR and Docking Journal of Molecular Graphics & Modelling. Jan, 2009 | Pubmed ID: 19081278 A Novel Method for Protein-ligand Binding Affinity Prediction and the Related Descriptors Exploration Journal of Computational Chemistry. Apr, 2009 | Pubmed ID: 18785151 Study of the Interaction of Aglycon of Daunorubicin with Human Serum Albumin by Spectroscopy and Modeling Macromolecular Bioscience. Dec, 2008 | Pubmed ID: 18785686 Interaction of Anthracycline Disaccharide with Human Serum Albumin: Investigation by Fluorescence Spectroscopic Technique and Modeling Studies Journal of Pharmaceutical and Biomedical Analysis. Nov, 2008 | Pubmed ID: 18722067 Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) of Thiazolone Derivatives As Hepatitis C Virus NS5B Polymerase Allosteric Inhibitors Journal of Computer-aided Molecular Design. Oct, 2008 | Pubmed ID: 18716715 A Concise Approach to 1,11-didechloro-6-methyl-4'-O-demethyl Rebeccamycin and Its Binding to Human Serum Albumin: Fluorescence Spectroscopy and Molecular Modeling Method Bioorganic & Medicinal Chemistry. Aug, 2008 | Pubmed ID: 18653350 QSAR Study of Malonyl-CoA Decarboxylase Inhibitors Using GA-MLR and a New Strategy of Consensus Modeling Journal of Computational Chemistry. Dec, 2008 | Pubmed ID: 18484640 The Alpha1a-adrenergic Receptor Occupies Membrane Rafts with Its G Protein Effectors but Internalizes Via Clathrin-coated Pits The Journal of Biological Chemistry. Feb, 2008 | Pubmed ID: 18048357 Novel Human Alpha1a-adrenoceptor Single Nucleotide Polymorphisms Alter Receptor Pharmacology and Biological Function Naunyn-Schmiedeberg's Archives of Pharmacology. Mar, 2005 | Pubmed ID: 15900517 Cellular Trafficking of Human Alpha1a-adrenergic Receptors is Continuous and Primarily Agonist-independent Molecular Pharmacology. Oct, 2004 | Pubmed ID: 15258254 Changes in MRNA Expression Induced by Sustained Noradrenaline Stimulation Are Different for Alpha1-adrenoceptor Subtypes in HEK293 Cells Clinical and Experimental Pharmacology & Physiology. Dec, 2002 | Pubmed ID: 12390296 Intrastriatal Injection of Autologous Blood or Clostridial Collagenase as Murine Models of Intracerebral Hemorrhage Beilei Lei1, Huaxin Sheng1, Haichen Wang2, Christopher D. Lascola3, David S. Warner1,4, Daniel T. Laskowitz1,2,4, Michael L. James1,2 1Multidisciplinary Neuroprotection Laboratories, Department of Anesthesiology, Duke University, 2Department of Neurology, Duke University, 3Department of Radiology, Duke University, 4Department of Neurobiology, Duke University JoVE 51439 Medicine
Intrastriatal Injection of Autologous Blood or Clostridial Collagenase as Murine Models of Intracerebral Hemorrhage Beilei Lei1, Huaxin Sheng1, Haichen Wang2, Christopher D. Lascola3, David S. Warner1,4, Daniel T. Laskowitz1,2,4, Michael L. James1,2 1Multidisciplinary Neuroprotection Laboratories, Department of Anesthesiology, Duke University, 2Department of Neurology, Duke University, 3Department of Radiology, Duke University, 4Department of Neurobiology, Duke University JoVE 51439 Medicine
