Bruce L. Levine Center for Cellular Immunotherapies, Perelman School of Medicine University of Pennsylvania Biography Publications Institution JoVE Articles Bruce L. Levine has not added a biography. If you are Bruce L. Levine and would like to personalize this page please email our Author Liaison for assistance. Publications B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Re-expansion in a Patient with Myeloma Following Salvage Programmed Cell Death Protein 1 Inhibitor-based Combination Therapy British Journal of Haematology. Mar, 2021 | Pubmed ID: 33713436 CCR5-edited CD4 T Cells Augment HIV-specific Immunity to Enable Post Rebound Control of HIV Replication The Journal of Clinical Investigation. Feb, 2021 | Pubmed ID: 33571163 Author Correction: Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy of Chronic Lymphocytic Leukemia Nature Medicine. Feb, 2021 | Pubmed ID: 33547459 The Coronavirus Pandemic: A Pitfall or a Fast Track for Validating Cell Therapy Products? Stem Cells and Development. 02, 2021 | Pubmed ID: 33307968 Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals Molecular Therapy : the Journal of the American Society of Gene Therapy. 02, 2021 | Pubmed ID: 33186691 Diagnostic Biomarkers to Differentiate Sepsis from Cytokine Release Syndrome in Critically Ill Children Blood Advances. 10, 2020 | Pubmed ID: 33095872 Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer Molecular Therapy : the Journal of the American Society of Gene Therapy. 11, 2020 | Pubmed ID: 32730744 Emerging Trends in COVID-19 Treatment: Learning from Inflammatory Conditions Associated with Cellular Therapies Cytotherapy. 09, 2020 | Pubmed ID: 32565132 International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy Statement on Extracellular Vesicles from Mesenchymal Stromal Cells and Other Cells: Considerations for Potential Therapeutic Agents to Suppress Coronavirus Disease-19 Cytotherapy. 09, 2020 | Pubmed ID: 32425691 Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 09, 2020 | Pubmed ID: 32298202 Accelerating the Development of Innovative Cellular Therapy Products for the Treatment of Cancer Cytotherapy. 05, 2020 | Pubmed ID: 32199724 CRISPR-engineered T Cells in Patients with Refractory Cancer Science (New York, N.Y.). 02, 2020 | Pubmed ID: 32029687 The Long Road to the First FDA-approved Gene Therapy: Chimeric Antigen Receptor T Cells Targeting CD19 Cytotherapy. 02, 2020 | Pubmed ID: 32014447 CAR T-cell Product Performance in Haematological Malignancies Before and After Marketing Authorisation The Lancet. Oncology. 02, 2020 | Pubmed ID: 32007196 CD19-targeting CAR T Cell Immunotherapy Outcomes Correlate with Genomic Modification by Vector Integration The Journal of Clinical Investigation. 02, 2020 | Pubmed ID: 31845905 Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 02, 2020 | Pubmed ID: 31815579 Approaches of T Cell Activation and Differentiation for CAR-T Cell Therapies Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 31707678 T-cell Phenotypes Associated with Effective CAR T-cell Therapy in Postinduction Vs Relapsed Multiple Myeloma Blood Advances. 10, 2019 | Pubmed ID: 31575532 CAR T Cell Viability Release Testing and Clinical Outcomes: is There a Lower Limit? Blood. 11, 2019 | Pubmed ID: 31554634 A Multiscale Simulation Framework for the Manufacturing Facility and Supply Chain of Autologous Cell Therapies Cytotherapy. 10, 2019 | Pubmed ID: 31445816 Phase I Study of Lentiviral-Transduced Chimeric Antigen Receptor-Modified T Cells Recognizing Mesothelin in Advanced Solid Cancers Molecular Therapy : the Journal of the American Society of Gene Therapy. 11, 2019 | Pubmed ID: 31420241 B Cell Maturation Antigen-specific CAR T Cells Are Clinically Active in Multiple Myeloma The Journal of Clinical Investigation. 03, 2019 | Pubmed ID: 30896447 Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells CPT: Pharmacometrics & Systems Pharmacology. 05, 2019 | Pubmed ID: 30848084 Chimeric Antigen Receptor-T Cell Therapy Manufacturing: Modelling the Effect of Offshore Production on Aggregate Cost of Goods Cytotherapy. 02, 2019 | Pubmed ID: 30770285 Powered and Controlled T-cell Production Nature Biomedical Engineering. 03, 2018 | Pubmed ID: 31015722 CAR T Cell Therapy of Non-hematopoietic Malignancies: Detours on the Road to Clinical Success Frontiers in Immunology. 2018 | Pubmed ID: 30559740 Induction of Resistance to Chimeric Antigen Receptor T Cell Therapy by Transduction of a Single Leukemic B Cell Nature Medicine. 10, 2018 | Pubmed ID: 30275568 Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 12, 2018 | Pubmed ID: 30190371 Reducing Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells Cancer Immunology Research. 09, 2018 | Pubmed ID: 30030295 Nonviral RNA Chimeric Antigen Receptor-modified T Cells in Patients with Hodgkin Lymphoma Blood. 09, 2018 | Pubmed ID: 29925499 Disruption of TET2 Promotes the Therapeutic Efficacy of CD19-targeted T Cells Nature. 06, 2018 | Pubmed ID: 29849141 Determinants of Response and Resistance to CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy of Chronic Lymphocytic Leukemia Nature Medicine. 05, 2018 | Pubmed ID: 29713085 Anti-CD19 CAR T Cells with High-dose Melphalan and Autologous Stem Cell Transplantation for Refractory Multiple Myeloma JCI Insight. 04, 2018 | Pubmed ID: 29669947 Personalized Cancer Vaccine Effectively Mobilizes Antitumor T Cell Immunity in Ovarian Cancer Science Translational Medicine. 04, 2018 | Pubmed ID: 29643231 Activity of Mesothelin-Specific Chimeric Antigen Receptor T Cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial Gastroenterology. 07, 2018 | Pubmed ID: 29567081 Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia The New England Journal of Medicine. 02, 2018 | Pubmed ID: 29385370 Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology Patients Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018 | Pubmed ID: 29203150 Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas The New England Journal of Medicine. 12, 2017 | Pubmed ID: 29226764 Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer Cancer Immunology Research. 12, 2017 | Pubmed ID: 29109077 Exploring Synthetic Immunity: From Boutique to Global Human Vaccines & Immunotherapeutics. 10, 2017 | Pubmed ID: 28945504 Cellular Kinetics of CTL019 in Relapsed/refractory B-cell Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia Blood. 11, 2017 | Pubmed ID: 28935694 Considerations in T Cell Therapy Product Development for B Cell Leukemia and Lymphoma Immunotherapy Current Hematologic Malignancy Reports. 08, 2017 | Pubmed ID: 28762038 A Single Dose of Peripherally Infused EGFRvIII-directed CAR T Cells Mediates Antigen Loss and Induces Adaptive Resistance in Patients with Recurrent Glioblastoma Science Translational Medicine. 07, 2017 | Pubmed ID: 28724573 Monocyte Lineage-derived IL-6 Does Not Affect Chimeric Antigen Receptor T-cell Function Cytotherapy. 07, 2017 | Pubmed ID: 28506444 Global Manufacturing of CAR T Cell Therapy Molecular Therapy. Methods & Clinical Development. Mar, 2017 | Pubmed ID: 28344995 Showcasing Clinical Development and Production of Cellular Therapies Molecular Therapy : the Journal of the American Society of Gene Therapy. 04, 2017 | Pubmed ID: 28341560 PD-1 Blockade Modulates Chimeric Antigen Receptor (CAR)-modified T Cells: Refueling the CAR Blood. 02, 2017 | Pubmed ID: 28031179 Optimization of CGMP Purification and Expansion of Umbilical Cord Blood-derived T-regulatory Cells in Support of First-in-human Clinical Trials Cytotherapy. 02, 2017 | Pubmed ID: 27887864 Engineered T Cells: the Promise and Challenges of Cancer Immunotherapy Nature Reviews. Cancer. 08, 2016 | Pubmed ID: 27550819 MiR-146b Antagomir-treated Human Tregs Acquire Increased GVHD Inhibitory Potency Blood. 09, 2016 | Pubmed ID: 27485827 Novel Gene and Cellular Therapy Approaches for Treating HIV Discovery Medicine. 04, 2016 | Pubmed ID: 27232514 Identification of Predictive Biomarkers for Cytokine Release Syndrome After Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia Cancer Discovery. 06, 2016 | Pubmed ID: 27076371 Chimeric Antigen Receptor T-Cell Therapy for the Community Oncologist The Oncologist. 05, 2016 | Pubmed ID: 27009942 Infusion of CD3/CD28 Costimulated Umbilical Cord Blood T Cells at the Time of Single Umbilical Cord Blood Transplantation May Enhance Engraftment American Journal of Hematology. May, 2016 | Pubmed ID: 26858124 Smart CARS: Optimized Development of a Chimeric Antigen Receptor (CAR) T Cell Targeting Epidermal Growth Factor Receptor Variant III (EGFRvIII) for Glioblastoma Annals of Translational Medicine. Jan, 2016 | Pubmed ID: 26855949 Ibrutinib Enhances Chimeric Antigen Receptor T-cell Engraftment and Efficacy in Leukemia Blood. Mar, 2016 | Pubmed ID: 26813675 Phase I Study of Multi-gene Cell Therapy in Patients with Peripheral Artery Disease Vascular Medicine (London, England). Feb, 2016 | Pubmed ID: 26584888 Umbilical Cord Blood-derived T Regulatory Cells to Prevent GVHD: Kinetics, Toxicity Profile, and Clinical Effect Blood. Feb, 2016 | Pubmed ID: 26563133 T Cell Engineering As Therapy for Cancer and HIV: Our Synthetic Future Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Oct, 2015 | Pubmed ID: 26416683 Chimeric Antigen Receptor T Cells Against CD19 for Multiple Myeloma The New England Journal of Medicine. Sep, 2015 | Pubmed ID: 26352815 Chimeric Antigen Receptor T Cells Persist and Induce Sustained Remissions in Relapsed Refractory Chronic Lymphocytic Leukemia Science Translational Medicine. Sep, 2015 | Pubmed ID: 26333935 NY-ESO-1-specific TCR-engineered T Cells Mediate Sustained Antigen-specific Antitumor Effects in Myeloma Nature Medicine. Aug, 2015 | Pubmed ID: 26193344 High-Dose Sirolimus and Immune-Selective Pentostatin Plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-versus-Tumor Responses Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2015 | Pubmed ID: 26071480 The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2015 | Pubmed ID: 25712684 Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia The New England Journal of Medicine. Oct, 2014 | Pubmed ID: 25317870 Engineered T Cells for Cancer Therapy Cancer Immunology, Immunotherapy : CII. Sep, 2014 | Pubmed ID: 24943274 Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV The New England Journal of Medicine. Mar, 2014 | Pubmed ID: 24597865 Mesothelin-specific Chimeric Antigen Receptor MRNA-engineered T Cells Induce Anti-tumor Activity in Solid Malignancies Cancer Immunology Research. Feb, 2014 | Pubmed ID: 24579088 Combination Immunotherapy After ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-primed and Costimulated Autologous T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2014 | Pubmed ID: 24520093 Adoptive Immunotherapy for Cancer or Viruses Annual Review of Immunology. 2014 | Pubmed ID: 24423116 T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans Cancer Immunology Research. Jul, 2013 | Pubmed ID: 24777247 T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans Cancer Immunology Research. Jul, 2013 | Pubmed ID: 24432303 Identification of a Titin-derived HLA-A1-presented Peptide As a Cross-reactive Target for Engineered MAGE A3-directed T Cells Science Translational Medicine. Aug, 2013 | Pubmed ID: 23926201 A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: from Bench to Bedside Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2013 | Pubmed ID: 23838316 Cardiovascular Toxicity and Titin Cross-reactivity of Affinity-enhanced T Cells in Myeloma and Melanoma Blood. Aug, 2013 | Pubmed ID: 23770775 Pilot Study of Prophylactic Ex Vivo Costimulated Donor Leukocyte Infusion After Reduced-intensity Conditioned Allogeneic Stem Cell Transplantation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Jul, 2013 | Pubmed ID: 23635453 Innovation and Opportunity for Chimeric Antigen Receptor Targeted T cells Cytotherapy. Sep, 2013 | Pubmed ID: 23562306 Chimeric Antigen Receptor-modified T Cells for Acute Lymphoid Leukemia The New England Journal of Medicine. Apr, 2013 | Pubmed ID: 23527958 Autologous Lysate-pulsed Dendritic Cell Vaccination Followed by Adoptive Transfer of Vaccine-primed Ex Vivo Co-stimulated T Cells in Recurrent Ovarian Cancer Oncoimmunology. Jan, 2013 | Pubmed ID: 23482679 Phase 2 Clinical Trial of Rapamycin-resistant Donor CD4+ Th2/Th1 (T-Rapa) Cells After Low-intensity Allogeneic Hematopoietic Cell Transplantation Blood. Apr, 2013 | Pubmed ID: 23426943 Efficient Clinical Scale Gene Modification Via Zinc Finger Nuclease-targeted Disruption of the HIV Co-receptor CCR5 Human Gene Therapy. Mar, 2013 | Pubmed ID: 23360514 Antiviral Effects of Autologous CD4 T Cells Genetically Modified with a Conditionally Replicating Lentiviral Vector Expressing Long Antisense to HIV Blood. Feb, 2013 | Pubmed ID: 23264589 Convergence of Gene and Cell Therapy Regenerative Medicine. Nov, 2012 | Pubmed ID: 23210811 Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 12, 2012 | Pubmed ID: 23092876 Decade-long Safety and Function of Retroviral-modified Chimeric Antigen Receptor T Cells Science Translational Medicine. May, 2012 | Pubmed ID: 22553251 Costimulated Tumor-infiltrating Lymphocytes Are a Feasible and Safe Alternative Donor Cell Therapy for Relapse After Allogeneic Stem Cell Transplantation Blood. Mar, 2012 | Pubmed ID: 22289893 Phase I/II Randomized Trial of Dendritic Cell Vaccination with or Without Cyclophosphamide for Consolidation Therapy of Advanced Ovarian Cancer in First or Second Remission Cancer Immunology, Immunotherapy : CII. May, 2012 | Pubmed ID: 22021066 The PDL1-PD1 Axis Converts Human TH1 Cells into Regulatory T Cells Science Translational Medicine. Nov, 2011 | Pubmed ID: 22133721 Optimizing Parameters for Clinical-scale Production of High IL-12 Secreting Dendritic Cells Pulsed with Oxidized Whole Tumor Cell Lysate Journal of Translational Medicine. Nov, 2011 | Pubmed ID: 22082029 Phase I Trial of Adoptive Cell Transfer with Mixed-profile Type-I/type-II Allogeneic T Cells for Metastatic Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2011 | Pubmed ID: 21948234 T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia Science Translational Medicine. Aug, 2011 | Pubmed ID: 21832238 Chimeric Antigen Receptor-modified T Cells in Chronic Lymphoid Leukemia The New England Journal of Medicine. Aug, 2011 | Pubmed ID: 21830940 Engineered Artificial Antigen Presenting Cells Facilitate Direct and Efficient Expansion of Tumor Infiltrating Lymphocytes Journal of Translational Medicine. Aug, 2011 | Pubmed ID: 21827675 Massive Ex Vivo Expansion of Human Natural Regulatory T Cells (T(regs)) with Minimal Loss of in Vivo Functional Activity Science Translational Medicine. May, 2011 | Pubmed ID: 21593401 Combination Immunotherapy Using Adoptive T-cell Transfer and Tumor Antigen Vaccination on the Basis of HTERT and Survivin After ASCT for Myeloma Blood. Jan, 2011 | Pubmed ID: 21030558 Infusion of Ex Vivo Expanded T Regulatory Cells in Adults Transplanted with Umbilical Cord Blood: Safety Profile and Detection Kinetics Blood. Jan, 2011 | Pubmed ID: 20952687 Transfer of Influenza Vaccine-primed Costimulated Autologous T Cells After Stem Cell Transplantation for Multiple Myeloma Leads to Reconstitution of Influenza Immunity: Results of a Randomized Clinical Trial Blood. Jan, 2011 | Pubmed ID: 20864577 Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor Cancer Research. Nov, 2010 | Pubmed ID: 20926399 Program Death-1 Signaling and Regulatory T Cells Collaborate to Resist the Function of Adoptively Transferred Cytotoxic T Lymphocytes in Advanced Acute Myeloid Leukemia Blood. Oct, 2010 | Pubmed ID: 20570856 Rapamycin Generates Anti-apoptotic Human Th1/Tc1 Cells Via Autophagy for Induction of Xenogeneic GVHD Autophagy. May, 2010 | Pubmed ID: 20404486 4-1BB and CD28 Signaling Plays a Synergistic Role in Redirecting Umbilical Cord Blood T Cells Against B-cell Malignancies Human Gene Therapy. Jan, 2010 | Pubmed ID: 19719389 Efficient Clinical-scale Enrichment of Lymphocytes for Use in Adoptive Immunotherapy Using a Modified Counterflow Centrifugal Elutriation Program Cytotherapy. 2009 | Pubmed ID: 19903104 Depletion of Endogenous Tumor-associated Regulatory T Cells Improves the Efficacy of Adoptive Cytotoxic T-cell Immunotherapy in Murine Acute Myeloid Leukemia Blood. Oct, 2009 | Pubmed ID: 19724059 Rapid Immune Recovery and Graft-versus-host Disease-like Engraftment Syndrome Following Adoptive Transfer of Costimulated Autologous T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009 | Pubmed ID: 19509133 Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2009 | Pubmed ID: 19259065 Adoptive Immunotherapy: Good Habits Instilled at Youth Have Long-term Benefits Immunologic Research. 2008 | Pubmed ID: 18949448 CD28 Costimulation is Essential for Human T Regulatory Expansion and Function Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18684977 A More Precise HIV Integration Assay Designed to Detect Small Differences Finds Lower Levels of Integrated DNA in HAART Treated Patients Virology. Sep, 2008 | Pubmed ID: 18649912 T Lymphocyte Engineering Ex Vivo for Cancer and Infectious Disease Expert Opinion on Biological Therapy. Apr, 2008 | Pubmed ID: 18352851 Identification and in Vitro Expansion of Functional Antigen-specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection Journal of Virology. May, 2008 | Pubmed ID: 18337568 Sleeping Beauty Transposon-mediated Engineering of Human Primary T Cells for Therapy of CD19+ Lymphoid Malignancies Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2008 | Pubmed ID: 18227839 Umbilical Cord Blood Xenografts in Immunodeficient Mice Reveal That T Cells Enhance Hematopoietic Engraftment Beyond Overcoming Immune Barriers by Stimulating Stem Cell Differentiation Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Oct, 2007 | Pubmed ID: 17889349 CD28-mediated Regulation of Multiple Myeloma Cell Proliferation and Survival Blood. Jun, 2007 | Pubmed ID: 17311991 Targeting HER-2/neu in Early Breast Cancer Development Using Dendritic Cells with Staged Interleukin-12 Burst Secretion Cancer Research. Feb, 2007 | Pubmed ID: 17293384 Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17090675 Stable Gene Transfer and Expression in Human Primary T Cells by the Sleeping Beauty Transposon System Blood. Jan, 2006 | Pubmed ID: 16189271 Adoptive Transfer of Costimulated T Cells Induces Lymphocytosis in Patients with Relapsed/refractory Non-Hodgkin Lymphoma Following CD34+-selected Hematopoietic Cell Transplantation Blood. Sep, 2003 | Pubmed ID: 12763934 TRANCE- and CD40 Ligand-matured Dendritic Cells Reveal MHC Class I-restricted T Cells Specific for Autologous Tumor in Late-stage Ovarian Cancer Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2003 | Pubmed ID: 12684428 Adoptive Transfer of Costimulated CD4+ T Cells Induces Expansion of Peripheral T Cells and Decreased CCR5 Expression in HIV Infection Nature Medicine. Jan, 2002 | Pubmed ID: 11786906 İnsan CRISPR-Engineered CAR-T Hücrelerinin Üretimi Sangya Agarwal*1,2, Nils Wellhausen*1,2, Bruce L. Levine1,2, Carl H. June1,2 1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, 2Parker Institute for Cancer Immunotherapy, University of Pennsylvania JoVE 62299 Immunology and Infection
İnsan CRISPR-Engineered CAR-T Hücrelerinin Üretimi Sangya Agarwal*1,2, Nils Wellhausen*1,2, Bruce L. Levine1,2, Carl H. June1,2 1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, 2Parker Institute for Cancer Immunotherapy, University of Pennsylvania JoVE 62299 Immunology and Infection