Christiane Bruns Department of General, Visceral, Cancer and Transplantation Surgery University Hospital Cologne Biography Publications Institution JoVE Articles Christiane Bruns has not added a biography. If you are Christiane Bruns and would like to personalize this page please email our Author Liaison for assistance. Publications Targeted Therapy for Adrenocortical Carcinoma: A Genomic-Based Search for Available and Emerging Options Cancers. May, 2022 | Pubmed ID: 35681700 Resistance Mechanisms of the Metastatic Tumor Microenvironment to Anti-Angiogenic Therapy Frontiers in Oncology. 2022 | Pubmed ID: 35664794 Influence of Patient Sex on Outcomes After Pancreatic Surgery: Multicentre Study The British Journal of Surgery. May, 2022 | Pubmed ID: 35574811 Adrenal Surgery in the Era of Multidisciplinary Endocrine Tumor Boards Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. May, 2022 | Pubmed ID: 35533674 Fructose-1,6-bisphosphatase 1 (FBP1) is an Independent Biomarker Associated with a Favorable Prognosis in Esophageal Adenocarcinoma Journal of Cancer Research and Clinical Oncology. Apr, 2022 | Pubmed ID: 35477823 [Synopsis-S3 Guidelines Pancreatic Cancer] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. 05, 2022 | Pubmed ID: 35471458 Long-Term Outcome After Histopathological Complete Response with and Without Nodal Metastases Following Multimodal Treatment of Esophageal Cancer Annals of Surgical Oncology. Apr, 2022 | Pubmed ID: 35403919 International Tumor Budding Consensus Conference Criteria Determine the Prognosis of Oesophageal Adenocarcinoma with Poor Response to Neoadjuvant Treatment Pathology, Research and Practice. Apr, 2022 | Pubmed ID: 35316631 Anaplastic Thyroid Cancer: Genome-based Search for New Targeted Therapy Options Endocrine Connections. Apr, 2022 | Pubmed ID: 35275096 Expression of Neighbor of Punc E11 (NOPE) in Early Stage Esophageal Adenocarcinoma is Associated with Reduced Survival Scientific Reports. 03, 2022 | Pubmed ID: 35246597 Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures As Correlates of Impaired Cancer Immunosurveillance Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 04, 2022 | Pubmed ID: 35191474 Definitions and Treatment of Oligometastatic Oesophagogastric Cancer According to Multidisciplinary Tumour Boards in Europe European Journal of Cancer (Oxford, England : 1990). 03, 2022 | Pubmed ID: 35134666 T-cells of Invasive Candidiasis Patients Show Patterns of T-cell-exhaustion Suggesting Checkpoint Blockade As Treatment Option The Journal of Infection. 02, 2022 | Pubmed ID: 34921845 Gender Benefit in Laparoscopic Surgical Performance Using a 3D-display System: Data from a Randomized Cross-over Trial Surgical Endoscopy. Jun, 2022 | Pubmed ID: 34750707 Short-term Outcome of Ivor Lewis Esophagectomy Following Neoadjuvant Chemoradiation Versus Perioperative Chemotherapy in Patients with Locally Advanced Adenocarcinoma of the Esophagus and Gastroesophageal Junction: a Propensity Score-matched Analysis Journal of Cancer Research and Clinical Oncology. May, 2022 | Pubmed ID: 34223965 [Multimodal Treatment of Esophageal Cancer] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Dec, 2021 | Pubmed ID: 34842948 Comparison of Outcomes Between Neoadjuvant Chemoradiotherapy and Neoadjuvant Chemotherapy in Patients with Locally Advanced Esophageal Cancer: A Network Meta-analysis EClinicalMedicine. Dec, 2021 | Pubmed ID: 34805809 IL-17B/RB Activation in Pancreatic Stellate Cells Promotes Pancreatic Cancer Metabolism and Growth Cancers. Oct, 2021 | Pubmed ID: 34771503 Different Prevalence of Alarm, Dyspeptic and Reflux Symptoms in Patients with Cardia and Non-cardia Gastric Cancer Journal of Gastrointestinal and Liver Diseases : JGLD. 12, 2021 | Pubmed ID: 34752588 A Novel Hybrid Stent with Endoscopic Vacuum Therapy for Treating Leaks of the Upper Gastrointestinal Tract Visceral Medicine. Oct, 2021 | Pubmed ID: 34722723 Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis Frontiers in Endocrinology. 2021 | Pubmed ID: 34630336 Tumor Microenvironment of Esophageal Cancer Cancers. Sep, 2021 | Pubmed ID: 34572905 [Impact of COVID-19 in Visceral Surgery] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. 10, 2021 | Pubmed ID: 34559260 Palliation of Malignant Dysphagia with a Segmented Self-expanding Metal Stent: A STROBE-compliant Article Medicine. Aug, 2021 | Pubmed ID: 34449494 Occurrence of High Microsatellite-Instability/Mismatch Repair Deficiency in Nearly 2,000 Human Adenocarcinomas of the Gastrointestinal Tract, Pancreas, and Bile Ducts: A Study From a Large German Comprehensive Cancer Center Frontiers in Oncology. 2021 | Pubmed ID: 34367937 Neoadjuvant Therapy for Resectable Pancreatic Cancer: A New Standard of Care. Pooled Data From 3 Randomized Controlled Trials Annals of Surgery. 11, 2021 | Pubmed ID: 34334656 Characteristics of Early-Onset Vs Late-Onset Colorectal Cancer: A Review JAMA Surgery. 09, 2021 | Pubmed ID: 34190968 CD86 Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses Cancer Immunology Research. 09, 2021 | Pubmed ID: 34155067 Cancer-specific Immune Evasion and Substantial Heterogeneity Within Cancer Types Provide Evidence for Personalized Immunotherapy NPJ Precision Oncology. Jun, 2021 | Pubmed ID: 34135436 Endoscopic Vacuum Therapy Versus Stent Treatment of Esophageal Anastomotic Leaks (ESOLEAK): Study Protocol for a Prospective Randomized Phase 2 Trial Trials. Jun, 2021 | Pubmed ID: 34078426 Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma Via ROS Detoxification Cancers. May, 2021 | Pubmed ID: 34065695 Sex-specific Prognostic Effect of CD66b-positive Tumor-infiltrating Neutrophils (TANs) in Gastric and Esophageal Adenocarcinoma Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 11, 2021 | Pubmed ID: 34009535 Optimized PD-L1 Scoring of Gastric Cancer Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 09, 2021 | Pubmed ID: 33954872 Technique of Open and Minimally Invasive Intrathoracic Reconstruction Following Esophagectomy-an Expert Consensus Based on a Modified Delphi Process Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus. Nov, 2021 | Pubmed ID: 33846718 Quiescin Sulfhydryl Oxidase 1 Promotes Sorafenib-induced Ferroptosis in Hepatocellular Carcinoma by Driving EGFR Endosomal Trafficking and Inhibiting NRF2 Activation Redox Biology. 05, 2021 | Pubmed ID: 33770521 [Robotics in Visceral Surgery] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Feb, 2021 | Pubmed ID: 33566135 Value of Spectral Detector CT for Pretherapeutic, Locoregional Assessment of Esophageal Cancer European Journal of Radiology. Jan, 2021 | Pubmed ID: 33302024 Microwave Ablation Enhances Tumor-specific Immune Response in Patients with Hepatocellular Carcinoma Cancer Immunology, Immunotherapy : CII. Apr, 2021 | Pubmed ID: 33006650 Tumor Budding Assessed According to the Criteria of the International Tumor Budding Consensus Conference Determines Prognosis in Resected Esophageal Adenocarcinoma Virchows Archiv : an International Journal of Pathology. Mar, 2021 | Pubmed ID: 32761393 The Effect of Postoperative Complications After Minimally Invasive Esophagectomy on Long-term Survival: An International Multicenter Cohort Study Annals of Surgery. 12, 2021 | Pubmed ID: 31972650 GATA Binding Protein 6 (GATA6) is Co-amplified with PIK3CA in Patients with Esophageal Adenocarcinoma and is Linked to Neoadjuvant Therapy Journal of Cancer Research and Clinical Oncology. Dec, 2020 | Pubmed ID: 33300112 Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies Frontiers in Oncology. 2020 | Pubmed ID: 33194749 Interferon-Induced Protein With Multiple Tetratricopeptide Repeats 3 Is Associated With Response to Chemotherapy and Recurrence but Not With Survival Pancreas. Nov/Dec, 2020 | Pubmed ID: 33122518 Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma Journal of Immunology Research. 2020 | Pubmed ID: 33029538 3D Versus 4K Display System - Influence of "State-of-the-art"-Display Technique on Surgical Performance (IDOSP-study) in Minimally Invasive Surgery: A Randomized Cross-over Trial Annals of Surgery. 11, 2020 | Pubmed ID: 32833763 Inflammatory IFIT3 Renders Chemotherapy Resistance by Regulating Post-translational Modification of VDAC2 in Pancreatic Cancer Theranostics. 2020 | Pubmed ID: 32641986 Y Chromosome Loss is a Frequent Event in Barrett's Adenocarcinoma and Associated with Poor Outcome Cancers. Jun, 2020 | Pubmed ID: 32629877 Amplification of KRAS and Its Heterogeneity in Non-Asian Gastric Adenocarcinomas BMC Cancer. Jun, 2020 | Pubmed ID: 32571252 Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer Cells. 06, 2020 | Pubmed ID: 32560537 [Molecular Predictors for the Course of Disease and Individualized Therapy in Pancreatic Cancer] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Aug, 2020 | Pubmed ID: 32405728 Pelvic Exenteration Surgery in Patients with Locally Advanced Castration-naïve and Castration-resistant, Symptomatic Prostate Cancer BJU International. 09, 2020 | Pubmed ID: 32320130 Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer JNCI Cancer Spectrum. Feb, 2020 | Pubmed ID: 32296755 Cell Type-specific Transcriptomics of Esophageal Adenocarcinoma As a Scalable Alternative for Single Cell Transcriptomics Molecular Oncology. 06, 2020 | Pubmed ID: 32255255 Gastric Cancer in Autoimmune Gastritis: A Case-control Study from the German Centers of the StaR Project on Gastric Cancer Research United European Gastroenterology Journal. 03, 2020 | Pubmed ID: 32213076 [Neoadjuvant Chemoradiotherapy or Chemotherapy for Locally Advanced Esophageal Cancer?] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. May, 2020 | Pubmed ID: 32140748 [Bile Duct Surgery] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jan, 2020 | Pubmed ID: 31960111 Immune Profile and Immunosurveillance in Treatment-naive and Neoadjuvantly Treated Esophageal Adenocarcinoma Cancer Immunology, Immunotherapy : CII. Apr, 2020 | Pubmed ID: 31960110 PIK3CA and KRAS Amplification In Esophageal Adenocarcinoma and Their Impact on the Inflammatory Tumor Microenvironment and Prognosis Translational Oncology. Feb, 2020 | Pubmed ID: 31865178 Tumor Biology and Multidisciplinary Strategies of Oligometastasis in Gastrointestinal Cancers Seminars in Cancer Biology. 02, 2020 | Pubmed ID: 31445220 Anastomotic Techniques and Associated Morbidity in Total Minimally Invasive Transthoracic Esophagectomy: Results From the EsoBenchmark Database Annals of Surgery. 11, 2019 | Pubmed ID: 31634181 Upregulation of MiR-17-92 Cluster is Associated with Progression and Lymph Node Metastasis in Oesophageal Adenocarcinoma Scientific Reports. 08, 2019 | Pubmed ID: 31431687 Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer Cancers. Jun, 2019 | Pubmed ID: 31234517 [Sarcoma-Established and New Aspects and Challenges in Multimodal Management] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jun, 2019 | Pubmed ID: 31187213 Evaluation of Mechanical Properties of Segmented Esophageal Self-Expandable Metal Stents: Innovative Test Methods Are Needed Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. Sep, 2019 | Pubmed ID: 31161950 Corrigendum to "Targeting Cancer Stem Cells and Their Niche: Perspectives for Future Therapeutic Targets and Strategies" [Semin. Cancer Biol. (2018) (August) Pii: S1044-579X(18)30045-2, 139-155] Seminars in Cancer Biology. Aug, 2019 | Pubmed ID: 30850316 HER2/neu (ERBB2) Expression and Gene Amplification Correlates with Better Survival in Esophageal Adenocarcinoma BMC Cancer. Jan, 2019 | Pubmed ID: 30621632 An Experimental Model of Breast Cancer Cells: Informative Protocol for Culture Anticancer Research. Nov, 2018 | Pubmed ID: 30396943 [Primary Hepatobiliary Malignancy] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Nov, 2018 | Pubmed ID: 30377728 Somatic Alterations in Circulating Cell-free DNA of Oesophageal Carcinoma Patients During Primary Staging Are Indicative for Post-surgical Tumour Recurrence Scientific Reports. 10, 2018 | Pubmed ID: 30297788 FA01.02: THE EFFECT OF POSTOPERATIVE COMPLICATIONS AFTER MIE ON LONG-TERM SURVIVAL: A RETROSPECTIVE, MULTI-CENTER COHORT STUDY Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus. Sep, 2018 | Pubmed ID: 30219910 Targeting Cancer Stem Cells and Their Niche: Perspectives for Future Therapeutic Targets and Strategies Seminars in Cancer Biology. 12, 2018 | Pubmed ID: 30081228 [Role of Visceral Surgery in Oligometastization] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jul, 2018 | Pubmed ID: 29978326 Web-Based Immersive Patient Simulator As a Curricular Tool for Objective Structured Clinical Examination Preparation in Surgery: Development and Evaluation JMIR Serious Games. Jul, 2018 | Pubmed ID: 29973333 Update on Transumbilical Single-Incision Laparoscopic Assisted Appendectomy (TULAA) - Which Children Benefit and What Are the Complications? Klinische Padiatrie. Jul, 2018 | Pubmed ID: 29544230 [Oncological Surgery of the Stomach and Esophagus] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. 12, 2017 | Pubmed ID: 29177914 Defining Benchmarks for Transthoracic Esophagectomy: A Multicenter Analysis of Total Minimally Invasive Esophagectomy in Low Risk Patients Annals of Surgery. 11, 2017 | Pubmed ID: 28796646 [Range of Variation of Pancreaticojejunostomy in Pancreatic Head Resection] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jan, 2017 | Pubmed ID: 28054106 [Different Techniques for Pancreatic Anastomosis] Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen. Jan, 2017 | Pubmed ID: 27975123 食道腺癌オルガノイドの継代培養と凍結保存:単一細胞消化の長所と短所 Ningbo Fan*1, Lisa Raatz*1, Seung-Hun Chon1, Alexander Quaas2, Christiane Bruns1, Yue Zhao1 1Department of General, Visceral, Cancer and Transplantation Surgery, University Hospital Cologne, 2Institute of Pathology, University Hospital Cologne JoVE 63281 Cancer Research
食道腺癌オルガノイドの継代培養と凍結保存:単一細胞消化の長所と短所 Ningbo Fan*1, Lisa Raatz*1, Seung-Hun Chon1, Alexander Quaas2, Christiane Bruns1, Yue Zhao1 1Department of General, Visceral, Cancer and Transplantation Surgery, University Hospital Cologne, 2Institute of Pathology, University Hospital Cologne JoVE 63281 Cancer Research