Christophe Vanpouille Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development National Institutes of Health Biography Publications Institution JoVE Articles Christophe Vanpouille has not added a biography. If you are Christophe Vanpouille and would like to personalize this page please email our Author Liaison for assistance. Publications Human Cytomegalovirus-infected Cells Release Extracellular Vesicles That Carry Viral Surface Proteins Virology. 11, 2018 | Pubmed ID: 30165311 Histoculture and Infection with HIV of Functional Human Lymphoid Tissue on Gelfoam Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29572804 Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire AIDS Research and Human Retroviruses. Nov, 2017 | Pubmed ID: 29140108 Virtual Screening of Acyclovir Derivatives As Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside ProTides Journal of Medicinal Chemistry. Sep, 2017 | Pubmed ID: 28829913 Dual-targeted Anti-TB/anti-HIV Heterodimers Antiviral Research. Sep, 2017 | Pubmed ID: 28743447 A Common Anti-cytomegalovirus Drug, Ganciclovir, Inhibits HIV-1 Replication in Human Tissues Ex Vivo AIDS (London, England). 07, 2017 | Pubmed ID: 28657962 Vaginal Inhibits HIV-1 Replication in Human Tissues Frontiers in Microbiology. 2017 | Pubmed ID: 28579980 Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue Scientific Reports. May, 2017 | Pubmed ID: 28490736 HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection Journal of Acquired Immune Deficiency Syndromes (1999). 01, 2017 | Pubmed ID: 27548440 Monocytes but Not Lymphocytes Carrying HIV-1 on Their Surface Transmit Infection to Human Tissue Ex Vivo Journal of Virology. Nov, 2016 | Pubmed ID: 27558419 Standardization of a Cytometric P24-capture Bead-assay for the Detection of Main HIV-1 Subtypes Journal of Virological Methods. Apr, 2016 | Pubmed ID: 26808359 Distinct Cytokine/chemokine Network in Semen and Blood Characterize Different Stages of HIV Infection AIDS (London, England). Jan, 2016 | Pubmed ID: 26558730 Genital Cytomegalovirus Replication Predicts Syphilis Acquisition Among HIV-1 Infected Men Who Have Sex with Men PloS One. 2015 | Pubmed ID: 26061824 Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jun, 2015 | Pubmed ID: 25740794 A New Antiviral: Chimeric 3TC-AZT Phosphonate Efficiently Inhibits HIV-1 in Human Tissues Ex Vivo Antiviral Research. Sep, 2014 | Pubmed ID: 25010891 Histocultures (tissue Explants) in Human Retrovirology Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24158827 Design, Synthesis and Biological Evaluation of Phosphorodiamidate Prodrugs of Antiviral and Anticancer Nucleosides European Journal of Medicinal Chemistry. 2013 | Pubmed ID: 24177359 A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity PLoS Pathogens. 2013 | Pubmed ID: 23935482 Interleukin-7 Facilitates HIV-1 Transmission to Cervico-vaginal Tissue Ex Vivo PLoS Pathogens. Feb, 2013 | Pubmed ID: 23408885 HIV-1 Imposes Rigidity on Blood and Semen Cytokine Networks American Journal of Reproductive Immunology (New York, N.Y. : 1989). Dec, 2012 | Pubmed ID: 23006048 Microbicides: Still a Long Road to Success Trends in Microbiology. Aug, 2012 | Pubmed ID: 22705107 Exploiting the Anti-HIV-1 Activity of Acyclovir: Suppression of Primary and Drug-resistant HIV Isolates and Potentiation of the Activity by Ribavirin Antimicrobial Agents and Chemotherapy. May, 2012 | Pubmed ID: 22314523 Semen of HIV-1-infected Individuals: Local Shedding of Herpesviruses and Reprogrammed Cytokine Network The Journal of Infectious Diseases. Jan, 2012 | Pubmed ID: 22107749 Topical Tenofovir, a Microbicide Effective Against HIV, Inhibits Herpes Simplex Virus-2 Replication Cell Host & Microbe. Oct, 2011 | Pubmed ID: 22018238 Cervico-vaginal Tissue Ex Vivo As a Model to Study Early Events in HIV-1 Infection American Journal of Reproductive Immunology (New York, N.Y. : 1989). Mar, 2011 | Pubmed ID: 21223429 Contrasting Roles for TLR Ligands in HIV-1 Pathogenesis PloS One. Sep, 2010 | Pubmed ID: 20862220 HIV-1 Sexual Transmission: Early Events of HIV-1 Infection of Human Cervico-vaginal Tissue in an Optimized Ex Vivo Model Mucosal Immunology. May, 2010 | Pubmed ID: 20147895 A New Class of Dual-targeted Antivirals: Monophosphorylated Acyclovir Prodrug Derivatives Suppress Both Human Immunodeficiency Virus Type 1 and Herpes Simplex Virus Type 2 The Journal of Infectious Diseases. Feb, 2010 | Pubmed ID: 20085496 War and Peace Between Microbes: HIV-1 Interactions with Coinfecting Viruses Cell Host & Microbe. Nov, 2009 | Pubmed ID: 19917495 Acyclovir: a New Use for an Old Drug Current Opinion in Infectious Diseases. Dec, 2009 | Pubmed ID: 19726982 A Missed Point in Deciphering the Viral Synergy Between Herpes Simplex Virus and HIV The Lancet. Infectious Diseases. Sep, 2009 | Pubmed ID: 19695487 The Application of Phosphoramidate Protide Technology to Acyclovir Confers Anti-HIV Inhibition Journal of Medicinal Chemistry. Sep, 2009 | Pubmed ID: 19645484 Mechanisms Associated with HIV-1 Resistance to Acyclovir by the V75I Mutation in Reverse Transcriptase The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19509419 Coinfecting Viruses As Determinants of HIV Disease Current HIV/AIDS Reports. Feb, 2009 | Pubmed ID: 19149991 A Highly Sensitive and Dynamic Immunofluorescent Cytometric Bead Assay for the Detection of HIV-1 P24 Journal of Virological Methods. Apr, 2009 | Pubmed ID: 19100289 Acyclovir is Activated into a HIV-1 Reverse Transcriptase Inhibitor in Herpesvirus-infected Human Tissues Cell Host & Microbe. Sep, 2008 | Pubmed ID: 18779052 Interactions Between Human Immunodeficiency Virus Type 1 and Vaccinia Virus in Human Lymphoid Tissue Ex Vivo Journal of Virology. Nov, 2007 | Pubmed ID: 17804502 Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture Andrea Introini1,2, Christophe Vanpouille2, Wendy Fitzgerald2, Kristina Broliden1, Leonid Margolis2 1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health JoVE 57013 Immunology and Infection
Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture Andrea Introini1,2, Christophe Vanpouille2, Wendy Fitzgerald2, Kristina Broliden1, Leonid Margolis2 1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health JoVE 57013 Immunology and Infection
