Craig E. Wheelock

Publications

• Aspirin-triggered Lipoxin Inhibits Atherosclerosis Progression in ApoE(-/-) Mice
  British Journal of Pharmacology. Jan, 2017  |   Pubmed ID: 28071789
• New Insights into the Effects of Onion Consumption on Lipid Mediators Using a Diet-induced Model of Hypercholesterolemia
  Redox Biology. Dec, 2016  |   Pubmed ID: 28006722
• Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2016  |   Pubmed ID: 27481843
• Dietary Nitrate Improves Age-related Hypertension and Metabolic Abnormalities in Rats Via Modulation of Angiotensin II Receptor Signaling and Inhibition of Superoxide Generation
  Free Radical Biology & Medicine. Oct, 2016  |   Pubmed ID: 27474450
• Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension
  Journal of the American Heart Association. Jul, 2016  |   Pubmed ID: 27431647
• Arginase Inhibition Improves Microvascular Endothelial Function in Patients With Type 2 Diabetes Mellitus
  The Journal of Clinical Endocrinology and Metabolism. Nov, 2016  |   Pubmed ID: 27399350
• Peritoneal Dialysis Impairs Nitric Oxide Homeostasis and May Predispose Infants with Low Systolic Blood Pressure to Cerebral Ischemia
  Nitric Oxide : Biology and Chemistry. Aug, 2016  |   Pubmed ID: 27234508
• Linoleic Acid-derived Lipid Mediators Increase in a Female-dominated Subphenotype of COPD
  The European Respiratory Journal. Jun, 2016  |   Pubmed ID: 26965288
• Metabolite Profiling and Stable Isotope Tracing in Sorted Subpopulations of Mammalian Cells
  Analytical Chemistry. Mar, 2016  |   Pubmed ID: 26855138
• Activated Prostaglandin D2 Receptors on Macrophages Enhance Neutrophil Recruitment into the Lung
  The Journal of Allergy and Clinical Immunology. Mar, 2016  |   Pubmed ID: 26792210
• Lipid Mediator Profile in Vernix Caseosa Reflects Skin Barrier Development
  Scientific Reports. Nov, 2015  |   Pubmed ID: 26521946
• Peri-ovulatory Endocrine Regulation of the Prostanoid Pathways in the Bovine Uterus at Early Dioestrus
  Reproduction, Fertility, and Development. Oct, 2015  |   Pubmed ID: 26462544
• Circulating Levels of Sphingosine-1-phosphate Are Elevated in Severe, but Not Mild Psoriasis and Are Unresponsive to Anti-TNF-α Treatment
  Scientific Reports. Jul, 2015  |   Pubmed ID: 26174087
• Urinary Excretion of Lipid Mediators in Response to Repeated Eucapnic Voluntary Hyperpnea in Asthmatic Subjects
  Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2015  |   Pubmed ID: 26112240
• Effects of Long-term Dietary Nitrate Supplementation in Mice
  Redox Biology. Aug, 2015  |   Pubmed ID: 26068891
• Hexosylceramides As Intrathecal Markers of Worsening Disability in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2015  |   Pubmed ID: 25480867
• LC-MS Metabolomics of Psoriasis Patients Reveals Disease Severity-dependent Increases in Circulating Amino Acids That Are Ameliorated by Anti-TNFα Treatment
  Journal of Proteome Research. Jan, 2015  |   Pubmed ID: 25361234
• The Effect of Omega-3 Fatty Acids on Bronchial Hyperresponsiveness, Sputum Eosinophilia, and Mast Cell Mediators in Asthma
  Chest. Feb, 2015  |   Pubmed ID: 25321659
• High-dose Simvastatin Exhibits Enhanced Lipid-lowering Effects Relative to Simvastatin/ezetimibe Combination Therapy
  Circulation. Cardiovascular Genetics. Dec, 2014  |   Pubmed ID: 25516625
• Network Analysis in the Investigation of Chronic Respiratory Diseases. From Basics to Application
  American Journal of Respiratory and Critical Care Medicine. Nov, 2014  |   Pubmed ID: 25254605
• Cord Blood Mesenchymal Stem Cells Suppress DC-T Cell Proliferation Via Prostaglandin B2
  Stem Cells and Development. Jul, 2014  |   Pubmed ID: 24649980
• Dietary Nitrate Reduces Resting Metabolic Rate: a Randomized, Crossover Study in Humans
  The American Journal of Clinical Nutrition. Apr, 2014  |   Pubmed ID: 24500154
• Effects of Selective COX-2 Inhibition on Allergen-induced Bronchoconstriction and Airway Inflammation in Asthma
  The Journal of Allergy and Clinical Immunology. Aug, 2014  |   Pubmed ID: 24461582
• Lipid Mediator Profiles Differ Between Lung Compartments in Asthmatic and Healthy Humans
  The European Respiratory Journal. Feb, 2014  |   Pubmed ID: 24036245
• Trials and Tribulations of 'omics Data Analysis: Assessing Quality of SIMCA-based Multivariate Models Using Examples from Pulmonary Medicine
  Molecular BioSystems. Nov, 2013  |   Pubmed ID: 23999822
• Dendritic Cell Reprogramming by Endogenously Produced Lactic Acid
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2013  |   Pubmed ID: 23956421
• Quantification of Lipid Mediator Metabolites in Human Urine from Asthma Patients by Electrospray Ionization Mass Spectrometry: Controlling Matrix Effects
  Analytical Chemistry. Aug, 2013  |   Pubmed ID: 23863083
• Quantitative Metabolic Profiling of Lipid Mediators
  Molecular Nutrition & Food Research. Aug, 2013  |   Pubmed ID: 23828856
• Lipid Mediator Serum Profiles in Asthmatics Significantly Shift Following Dietary Supplementation with Omega-3 Fatty Acids
  Molecular Nutrition & Food Research. Aug, 2013  |   Pubmed ID: 23824870
• Application of 'omics Technologies to Biomarker Discovery in Inflammatory Lung Diseases
  The European Respiratory Journal. Sep, 2013  |   Pubmed ID: 23397306
• Lipid Mediator Metabolic Profiling Demonstrates Differences in Eicosanoid Patterns in Two Phenotypically Distinct Mast Cell Populations
  Journal of Lipid Research. Jan, 2013  |   Pubmed ID: 23034214
• Application of Metabolomics Approaches to the Study of Respiratory Diseases
  Bioanalysis. Sep, 2012  |   Pubmed ID: 23046268
• Building Multivariate Systems Biology Models
  Analytical Chemistry. Aug, 2012  |   Pubmed ID: 22856472
• Network Analysis Identifies a Putative Role for the PPAR and Type 1 Interferon Pathways in Glucocorticoid Actions in Asthmatics
  BMC Medical Genomics. Jun, 2012  |   Pubmed ID: 22713245
• Allergic Asthmatics Show Divergent Lipid Mediator Profiles from Healthy Controls Both at Baseline and Following Birch Pollen Provocation
  PloS One. 2012  |   Pubmed ID: 22438998
• Asthmatics Exhibit Altered Oxylipin Profiles Compared to Healthy Individuals After Subway Air Exposure
  PloS One. 2011  |   Pubmed ID: 21897859
• Lipid Mediator Profiling in Pulmonary Disease
  Current Pharmaceutical Biotechnology. Jul, 2011  |   Pubmed ID: 21466458
• 12- and 15-lipoxygenases in Human Carotid Atherosclerotic Lesions: Associations with Cerebrovascular Symptoms
  Atherosclerosis. Apr, 2011  |   Pubmed ID: 21316676
• Phylogenetic Analysis of Lipid Mediator GPCRs
  Genome Informatics. International Conference on Genome Informatics. 2010  |   Pubmed ID: 22081594
• Exosomes from Human Macrophages and Dendritic Cells Contain Enzymes for Leukotriene Biosynthesis and Promote Granulocyte Migration
  The Journal of Allergy and Clinical Immunology. Nov, 2010  |   Pubmed ID: 20728205
• Advances in Eicosanoid Research, Novel Therapeutic Implications
  Biochemical and Biophysical Research Communications. May, 2010  |   Pubmed ID: 20494126
• The Use of Network Analyses for Elucidating Mechanisms in Cardiovascular Disease
  Molecular BioSystems. Feb, 2010  |   Pubmed ID: 20094647
• VarDB: a Database of Antigenic Variant Sequences--current Status and Future Prospects
  Acta Tropica. Jun, 2010  |   Pubmed ID: 19539588
• Tools for Investigating Mechanisms of Antigenic Variation: New Extensions to VarDB
  Genome Informatics. International Conference on Genome Informatics. Oct, 2009  |   Pubmed ID: 20180261
• Bioinformatics Strategies for the Analysis of Lipids
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19784609
• HPLC/MS/MS-based Approaches for Detection and Quantification of Eicosanoids
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19763475
• Systems Biology Approaches and Pathway Tools for Investigating Cardiovascular Disease
  Molecular BioSystems. Jun, 2009  |   Pubmed ID: 19462016
• GeneRegionScan: a Bioconductor Package for Probe-level Analysis of Specific, Small Regions of the Genome
  Bioinformatics (Oxford, England). Aug, 2009  |   Pubmed ID: 19398447
• Comparison of Benzil and Trifluoromethyl Ketone (TFK)-mediated Carboxylesterase Inhibition Using Classical and 3D-quantitative Structure-activity Relationship Analysis
  Bioorganic & Medicinal Chemistry. Jan, 2009  |   Pubmed ID: 19062296
• Tissue Distribution, Isozyme Abundance and Sensitivity to Chlorpyrifos-oxon of Carboxylesterases in the Earthworm Lumbricus Terrestris
  Environmental Pollution (Barking, Essex : 1987). Jan, 2009  |   Pubmed ID: 18775596
• From Genome to Proteome: Integration and Proteome Completion - 8th Siena Meeting
  IDrugs : the Investigational Drugs Journal. Nov, 2008  |   Pubmed ID: 18988122
• VarDB: a Pathogen-specific Sequence Database of Protein Families Involved in Antigenic Variation
  Bioinformatics (Oxford, England). Nov, 2008  |   Pubmed ID: 18776192
• Applications of Carboxylesterase Activity in Environmental Monitoring and Toxicity Identification Evaluations (TIEs)
  Reviews of Environmental Contamination and Toxicology. 2008  |   Pubmed ID: 18418956
• Development of Metabolically Stable Inhibitors of Mammalian Microsomal Epoxide Hydrolase
  Chemical Research in Toxicology. Apr, 2008  |   Pubmed ID: 18363382
• Effects of Pyridine Exposure Upon Structural Lipid Metabolism in Swiss Webster Mice
  Chemical Research in Toxicology. Mar, 2008  |   Pubmed ID: 18251509
• Influence of Sulfur Oxidation State and Steric Bulk Upon Trifluoromethyl Ketone (TFK) Binding Kinetics to Carboxylesterases and Fatty Acid Amide Hydrolase (FAAH)
  Bioorganic & Medicinal Chemistry. Feb, 2008  |   Pubmed ID: 18023188
• Clofibrate-induced Changes in the Liver, Heart, Brain and White Adipose Lipid Metabolome of Swiss-Webster Mice
  Metabolomics : Official Journal of the Metabolomic Society. Jun, 2007  |   Pubmed ID: 19079556
• Identification of Endocrine Disruptor Biodegradation by Integration of Structure-activity Relationship with Pathway Analysis
  Environmental Science & Technology. Dec, 2007  |   Pubmed ID: 18186328
• PfEMP1-DBL1alpha Amino Acid Motifs in Severe Disease States of Plasmodium Falciparum Malaria
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007  |   Pubmed ID: 17895392
• Diverse Roles of 2-arachidonoylglycerol in Invasion of Prostate Carcinoma Cells: Location, Hydrolysis and 12-lipoxygenase Metabolism
  International Journal of Cancer. Sep, 2007  |   Pubmed ID: 17443494
• Analysis of Mammalian Carboxylesterase Inhibition by Trifluoromethylketone-containing Compounds
  Molecular Pharmacology. Mar, 2007  |   Pubmed ID: 17167034
• Use of Carboxylesterase Activity to Remove Pyrethroid-associated Toxicity to Ceriodaphnia Dubia and Hyalella Azteca in Toxicity Identification Evaluations
  Environmental Toxicology and Chemistry. Apr, 2006  |   Pubmed ID: 16629136
• Structural Studies of a Potent Insect Maturation Inhibitor Bound to the Juvenile Hormone Esterase of Manduca Sexta
  Biochemistry. Apr, 2006  |   Pubmed ID: 16566578
• High-throughput Screening of Ecdysone Agonists Using a Reporter Gene Assay Followed by 3-D QSAR Analysis of the Molting Hormonal Activity
  Bioorganic & Medicinal Chemistry. Feb, 2006  |   Pubmed ID: 16249087
• Evaluation of Alpha-cyano Ethers As Fluorescent Substrates for Assay of Cytochrome P450 Enzyme Activity
  Analytical Biochemistry. Sep, 2005  |   Pubmed ID: 16083846
• Individual Variability in Esterase Activity and CYP1A Levels in Chinook Salmon (Oncorhynchus Tshawytscha) Exposed to Esfenvalerate and Chlorpyrifos
  Aquatic Toxicology (Amsterdam, Netherlands). Aug, 2005  |   Pubmed ID: 16011852
• Influence of Container Adsorption Upon Observed Pyrethroid Toxicity to Ceriodaphnia Dubia and Hyalella Azteca
  Aquatic Toxicology (Amsterdam, Netherlands). Aug, 2005  |   Pubmed ID: 15951033
• A New Class of Inhibitors of 2-arachidonoylglycerol Hydrolysis and Invasion of Prostate Cancer Cells
  Biochemical and Biophysical Research Communications. Jul, 2005  |   Pubmed ID: 15919052
• Development of Toxicity Identification Evaluation Procedures for Pyrethroid Detection Using Esterase Activity
  Environmental Toxicology and Chemistry. Nov, 2004  |   Pubmed ID: 15559286
• Investigation of the Role of a Second Conserved Serine in Carboxylesterases Via Site-directed Mutagenesis
  Archives of Biochemistry and Biophysics. Oct, 2004  |   Pubmed ID: 15369824
• Identification, Expression, and Purification of a Pyrethroid-hydrolyzing Carboxylesterase from Mouse Liver Microsomes
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15123619
• Pyrethroid Tolerance in Culex Pipiens Pipiens Var Molestus from Marin County, California
  Pest Management Science. Apr, 2004  |   Pubmed ID: 15119598
• Use of Classical and 3-D QSAR to Examine the Hydration State of Juvenile Hormone Esterase Inhibitors
  Bioorganic & Medicinal Chemistry. Nov, 2003  |   Pubmed ID: 14604674
• Juvenile Hormone (JH) Esterase: Why Are You So JH Specific?
  Insect Biochemistry and Molecular Biology. Dec, 2003  |   Pubmed ID: 14599498
• Evaluation of Alpha-cyanoesters As Fluorescent Substrates for Examining Interindividual Variation in General and Pyrethroid-selective Esterases in Human Liver Microsomes
  Analytical Biochemistry. Apr, 2003  |   Pubmed ID: 12689831
• Joint Acute Toxicity of Esfenvalerate and Diazinon to Larval Fathead Minnows (Pimephales Promelas)
  Environmental Toxicology and Chemistry. Feb, 2003  |   Pubmed ID: 12558165
• Use of Ab Initio Calculations to Predict the Biological Potency of Carboxylesterase Inhibitors
  Journal of Medicinal Chemistry. Dec, 2002  |   Pubmed ID: 12459025
• Structural Refinement of Inhibitors of Urea-based Soluble Epoxide Hydrolases
  Biochemical Pharmacology. May, 2002  |   Pubmed ID: 12007563