David A. Hood Muscle Health Research Center, School of Kinesiology and Health Science York University Biography Publications Institution JoVE Articles David A. Hood has not added a biography. If you are David A. Hood and would like to personalize this page please email our Author Liaison for assistance. Publications P53 Regulates Skeletal Muscle Mitophagy and Mitochondrial Quality Control Following Denervation-induced Muscle Disuse The Journal of Biological Chemistry. Dec, 2021 | Pubmed ID: 34958797 Human Cardiac Ischemia-reperfusion Injury: Blunted Stress Response with Age Journal of Cardiac Surgery. Oct, 2021 | Pubmed ID: 34250631 Effect of Rapamycin on Mitochondria and Lysosomes in Fibroblasts from Patients with MtDNA Mutations American Journal of Physiology. Cell Physiology. 07, 2021 | Pubmed ID: 34106788 Mitochondrial Bioenergetics and Turnover During Chronic Muscle Disuse International Journal of Molecular Sciences. May, 2021 | Pubmed ID: 34068411 Examining Interindividual Differences in Select Muscle and Whole-body Adaptations to Continuous Endurance Training Experimental Physiology. Nov, 2021 | Pubmed ID: 33998072 Manifestations of Age on Autophagy, Mitophagy and Lysosomes in Skeletal Muscle Cells. 04, 2021 | Pubmed ID: 33946883 Exercise Is Muscle Mitochondrial Medicine Exercise and Sport Sciences Reviews. 04, 2021 | Pubmed ID: 33720909 Exercise and Mitochondrial Health The Journal of Physiology. 02, 2021 | Pubmed ID: 31674658 Molecular Basis for the Therapeutic Effects of Exercise on Mitochondrial Defects Frontiers in Physiology. 2020 | Pubmed ID: 33584337 Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults Cells. 12, 2020 | Pubmed ID: 33276460 The Intersection of Exercise and Aging on Mitochondrial Protein Quality Control Experimental Gerontology. 03, 2020 | Pubmed ID: 31911185 Looking Beyond PGC-1α: Emerging Regulators of Exercise-induced Skeletal Muscle Mitochondrial Biogenesis and Their Activation by Dietary Compounds Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Jan, 2020 | Pubmed ID: 31158323 Mitochondrial Breakdown in Skeletal Muscle and the Emerging Role of the Lysosomes Archives of Biochemistry and Biophysics. 01, 2019 | Pubmed ID: 30439362 Regulation of Autophagic and Mitophagic Flux During Chronic Contractile Activity-induced Muscle Adaptations Pflugers Archiv : European Journal of Physiology. 03, 2019 | Pubmed ID: 30368578 Maintenance of Skeletal Muscle Mitochondria in Health, Exercise, and Aging Annual Review of Physiology. 02, 2019 | Pubmed ID: 30216742 The Role of P53 in Determining Mitochondrial Adaptations to Endurance Training in Skeletal Muscle Scientific Reports. 10, 2018 | Pubmed ID: 30279494 Contractile Activity Attenuates Autophagy Suppression and Reverses Mitochondrial Defects in Skeletal Muscle Cells Autophagy. 2018 | Pubmed ID: 30078345 Effect of Tim23 Knockdown in Vivo on Mitochondrial Protein Import and Retrograde Signaling to the UPR in Muscle American Journal of Physiology. Cell Physiology. 10, 2018 | Pubmed ID: 29949403 Parkin is Required for Exercise-induced Mitophagy in Muscle: Impact of Aging American Journal of Physiology. Endocrinology and Metabolism. 09, 2018 | Pubmed ID: 29812989 Autophagy and Mitophagy Flux in Young and Aged Skeletal Muscle Following Chronic Contractile Activity The Journal of Physiology. 08, 2018 | Pubmed ID: 29781176 Role of Parkin and Endurance Training on Mitochondrial Turnover in Skeletal Muscle Skeletal Muscle. 03, 2018 | Pubmed ID: 29549884 Effect of Contractile Activity on PGC-1α Transcription in Young and Aged Skeletal Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). 06, 2018 | Pubmed ID: 29543139 A Systematic Review of P53 Regulation of Oxidative Stress in Skeletal Muscle Redox Report : Communications in Free Radical Research. Dec, 2018 | Pubmed ID: 29298131 Exercise Induces TFEB Expression and Activity in Skeletal Muscle in a PGC-1α-dependent Manner American Journal of Physiology. Cell Physiology. Jan, 2018 | Pubmed ID: 29046293 Regulation of the Autophagy System During Chronic Contractile Activity-induced Muscle Adaptations Physiological Reports. Jul, 2017 | Pubmed ID: 28720712 Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle Oxidative Medicine and Cellular Longevity. 2017 | Pubmed ID: 28656072 The Unfolded Protein Response in Relation to Mitochondrial Biogenesis in Skeletal Muscle Cells American Journal of Physiology. Cell Physiology. May, 2017 | Pubmed ID: 28274921 The Analysis of Knee Joint Loading During Drop Landing from Different Heights and Under Different Instruction Sets in Healthy Males Sports Medicine - Open. Dec, 2017 | Pubmed ID: 28101732 Function of Specialized Regulatory Proteins and Signaling Pathways in Exercise-induced Muscle Mitochondrial Biogenesis Integrative Medicine Research. Sep, 2016 | Pubmed ID: 28462117 The Role of Nrf2 in Skeletal Muscle Contractile and Mitochondrial Function Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2016 | Pubmed ID: 27471236 Unravelling the Mechanisms Regulating Muscle Mitochondrial Biogenesis The Biochemical Journal. 08, 2016 | Pubmed ID: 27470593 Chronology of UPR Activation in Skeletal Muscle Adaptations to Chronic Contractile Activity American Journal of Physiology. Cell Physiology. Jun, 2016 | Pubmed ID: 27122157 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 The Regulation of Autophagy During Exercise in Skeletal Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2016 | Pubmed ID: 26679612 Exercise and the Regulation of Mitochondrial Turnover Progress in Molecular Biology and Translational Science. 2015 | Pubmed ID: 26477912 The Regulation of Mitochondrial Transcription Factor A (Tfam) Expression During Skeletal Muscle Cell Differentiation Bioscience Reports. May, 2015 | Pubmed ID: 26182383 Effect of Denervation on the Regulation of Mitochondrial Transcription Factor A Expression in Skeletal Muscle American Journal of Physiology. Cell Physiology. Aug, 2015 | Pubmed ID: 26063705 Mitochondria, Muscle Health, and Exercise with Advancing Age Physiology (Bethesda, Md.). May, 2015 | Pubmed ID: 25933821 PGC-1α Modulates Denervation-induced Mitophagy in Skeletal Muscle Skeletal Muscle. 2015 | Pubmed ID: 25834726 Role of PGC-1α During Acute Exercise-induced Autophagy and Mitophagy in Skeletal Muscle American Journal of Physiology. Cell Physiology. May, 2015 | Pubmed ID: 25673772 Effect of P53 on Mitochondrial Morphology, Import, and Assembly in Skeletal Muscle American Journal of Physiology. Cell Physiology. Feb, 2015 | Pubmed ID: 25472962 Recent Advances in Mitochondrial Turnover During Chronic Muscle Disuse Integrative Medicine Research. Dec, 2014 | Pubmed ID: 28664093 Cytoskeletal Regulation of Mitochondrial Movements in Myoblasts Cytoskeleton (Hoboken, N.J.). Oct, 2014 | Pubmed ID: 25147078 Multiple Signaling Pathways Regulate Contractile Activity-mediated PGC-1α Gene Expression and Activity in Skeletal Muscle Cells Physiological Reports. May, 2014 | Pubmed ID: 24843073 Oxidative Stress-induced Mitochondrial Fragmentation and Movement in Skeletal Muscle Myoblasts American Journal of Physiology. Cell Physiology. Jun, 2014 | Pubmed ID: 24740540 P53 is Necessary for the Adaptive Changes in Cellular Milieu Subsequent to an Acute Bout of Endurance Exercise American Journal of Physiology. Cell Physiology. Feb, 2014 | Pubmed ID: 24284795 Altered Mitochondrial Morphology and Defective Protein Import Reveal Novel Roles for Bax And/or Bak in Skeletal Muscle American Journal of Physiology. Cell Physiology. Sep, 2013 | Pubmed ID: 23784543 Acute Exercise Induces Tumour Suppressor Protein P53 Translocation to the Mitochondria and Promotes a P53-Tfam-mitochondrial DNA Complex in Skeletal Muscle The Journal of Physiology. Jul, 2013 | Pubmed ID: 23690562 Expression of Mitochondrial Fission and Fusion Regulatory Proteins in Skeletal Muscle During Chronic Use and Disuse Muscle & Nerve. Dec, 2013 | Pubmed ID: 23494933 Endurance Training Ameliorates the Metabolic and Performance Characteristics of Circadian Clock Mutant Mice Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2013 | Pubmed ID: 23429867 Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23329826 The Effects of Chronic Muscle Use and Disuse on Cardiolipin Metabolism Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2013 | Pubmed ID: 23221956 Adaptive Plasticity of Autophagic Proteins to Denervation in Aging Skeletal Muscle American Journal of Physiology. Cell Physiology. Mar, 2013 | Pubmed ID: 23220115 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 MRNA Stability As a Function of Striated Muscle Oxidative Capacity American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2012 | Pubmed ID: 22718808 Denervation-induced Mitochondrial Dysfunction and Autophagy in Skeletal Muscle of Apoptosis-deficient Animals American Journal of Physiology. Cell Physiology. Aug, 2012 | Pubmed ID: 22673615 Mitochondrial Dysregulation in the Pathogenesis of Diabetes: Potential for Mitochondrial Biogenesis-mediated Interventions Experimental Diabetes Research. 2012 | Pubmed ID: 22203837 Plasticity of TOM Complex Assembly in Skeletal Muscle Mitochondria in Response to Chronic Contractile Activity Mitochondrion. Mar, 2012 | Pubmed ID: 22142511 The Role of SirT1 in Muscle Mitochondrial Turnover Mitochondrion. Jan, 2012 | Pubmed ID: 21406254 Mechanisms of Exercise-induced Mitochondrial Biogenesis in Skeletal Muscle: Implications for Health and Disease Comprehensive Physiology. Jul, 2011 | Pubmed ID: 23733637 Role of P53 Within the Regulatory Network Controlling Muscle Mitochondrial Biogenesis Exercise and Sport Sciences Reviews. Oct, 2011 | Pubmed ID: 21799424 Contractile Activity-induced Gene Expression in Fast- and Slow-twitch Muscle Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Apr, 2011 | Pubmed ID: 21609285 The Importance of PGC-1α in Contractile Activity-induced Mitochondrial Adaptations American Journal of Physiology. Endocrinology and Metabolism. Feb, 2011 | Pubmed ID: 21081705 Effect of Denervation-induced Muscle Disuse on Mitochondrial Protein Import American Journal of Physiology. Cell Physiology. Jan, 2011 | Pubmed ID: 20943961 Regulation of PPARγ Coactivator-1α Function and Expression in Muscle: Effect of Exercise PPAR Research. 2010 | Pubmed ID: 20847946 Effect of Chronic Contractile Activity on MRNA Stability in Skeletal Muscle American Journal of Physiology. Cell Physiology. Jul, 2010 | Pubmed ID: 20375275 Biogenesis of the Mitochondrial Tom40 Channel in Skeletal Muscle from Aged Animals and Its Adaptability to Chronic Contractile Activity American Journal of Physiology. Cell Physiology. Jun, 2010 | Pubmed ID: 20107041 Effect of Age on the Processing and Import of Matrix-destined Mitochondrial Proteins in Skeletal Muscle The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2010 | Pubmed ID: 20045872 Mitochondrial Dysfunction is Associated with a Pro-apoptotic Cellular Environment in Senescent Cardiac Muscle Mechanisms of Ageing and Development. Feb, 2010 | Pubmed ID: 20036683 Transcriptional and Post-transcriptional Regulation of Mitochondrial Biogenesis in Skeletal Muscle: Effects of Exercise and Aging Biochimica Et Biophysica Acta. Mar, 2010 | Pubmed ID: 19682549 Molecular Basis for an Attenuated Mitochondrial Adaptive Plasticity in Aged Skeletal Muscle Aging. Sep, 2009 | Pubmed ID: 20157569 Relationship Between Sirt1 Expression and Mitochondrial Proteins During Conditions of Chronic Muscle Use and Disuse Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2009 | Pubmed ID: 19797682 Specific Attenuation of Protein Kinase Phosphorylation in Muscle with a High Mitochondrial Content American Journal of Physiology. Endocrinology and Metabolism. Sep, 2009 | Pubmed ID: 19549794 Mechanisms of Exercise-induced Mitochondrial Biogenesis in Skeletal Muscle Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Jun, 2009 | Pubmed ID: 19448716 Diminished Contraction-induced Intracellular Signaling Towards Mitochondrial Biogenesis in Aged Skeletal Muscle Aging Cell. Aug, 2009 | Pubmed ID: 19416128 Age-associated Mitochondrial Dysfunction in Skeletal Muscle: Contributing Factors and Suggestions for Long-term Interventions IUBMB Life. Mar, 2009 | Pubmed ID: 19243006 Role of P53 in Mitochondrial Biogenesis and Apoptosis in Skeletal Muscle Physiological Genomics. Mar, 2009 | Pubmed ID: 19106183 Denervation-induced Oxidative Stress and Autophagy Signaling in Muscle Autophagy. Feb, 2009 | Pubmed ID: 19098460 Interactions Between ROS and AMP Kinase Activity in the Regulation of PGC-1alpha Transcription in Skeletal Muscle Cells American Journal of Physiology. Cell Physiology. Jan, 2009 | Pubmed ID: 19005163 AMP-activated Protein Kinase-regulated Activation of the PGC-1alpha Promoter in Skeletal Muscle Cells PloS One. 2008 | Pubmed ID: 18974883 Kinase-specific Responsiveness to Incremental Contractile Activity in Skeletal Muscle with Low and High Mitochondrial Content American Journal of Physiology. Endocrinology and Metabolism. Jul, 2008 | Pubmed ID: 18492778 Effect of Prior Chronic Contractile Activity on Mitochondrial Function and Apoptotic Protein Expression in Denervated Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2008 | Pubmed ID: 18450984 Mitochondrial Function and Apoptotic Susceptibility in Aging Skeletal Muscle Aging Cell. Jan, 2008 | Pubmed ID: 18028258 Thyroid Hormone (T3) Rapidly Activates P38 and AMPK in Skeletal Muscle in Vivo Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2008 | Pubmed ID: 17962579 The Effect of Training on the Expression of Mitochondrial Biogenesis- and Apoptosis-related Proteins in Skeletal Muscle of Patients with MtDNA Defects American Journal of Physiology. Endocrinology and Metabolism. Sep, 2007 | Pubmed ID: 17551003 Effect of Denervation on Mitochondrially Mediated Apoptosis in Skeletal Muscle Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2007 | Pubmed ID: 17122379 Effect of Chronic Contractile Activity on SS and IMF Mitochondrial Apoptotic Susceptibility in Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. Mar, 2007 | Pubmed ID: 17106065 Skeletal Muscle Stem Cells: a Symposium Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. Dec, 2006 | Pubmed ID: 17213898 Control of Gene Expression and Mitochondrial Biogenesis in the Muscular Adaptation to Endurance Exercise Essays in Biochemistry. 2006 | Pubmed ID: 17144877 Coordination of Metabolic Plasticity in Skeletal Muscle The Journal of Experimental Biology. Jun, 2006 | Pubmed ID: 16731803 How is Mitochondrial Biogenesis Affected in Mitochondrial Disease? Medicine and Science in Sports and Exercise. Dec, 2005 | Pubmed ID: 16331136 Mechanisms of Mitochondrial Disease and the Role of Exercise: a Symposium Medicine and Science in Sports and Exercise. Dec, 2005 | Pubmed ID: 16331133 Application of Animal Models: Chronic Electrical Stimulation-induced Contractile Activity Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquee. Oct, 2005 | Pubmed ID: 16293907 Differential Susceptibility of Subsarcolemmal and Intermyofibrillar Mitochondria to Apoptotic Stimuli American Journal of Physiology. Cell Physiology. Oct, 2005 | Pubmed ID: 15901602 Regulation of Egr-1, SRF, and Sp1 MRNA Expression in Contracting Skeletal Muscle Cells Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2004 | Pubmed ID: 15310743 Mitochondrial Assembly: Protein Import The Proceedings of the Nutrition Society. May, 2004 | Pubmed ID: 15294046 Role of UCP3 in State 4 Respiration During Contractile Activity-induced Mitochondrial Biogenesis Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2004 | Pubmed ID: 15145919 Calcium-regulated Changes in Mitochondrial Phenotype in Skeletal Muscle Cells American Journal of Physiology. Cell Physiology. May, 2004 | Pubmed ID: 15075204 Tissue-specific Regulation of Cytochrome C Oxidase Subunit Expression by Thyroid Hormone American Journal of Physiology. Endocrinology and Metabolism. Jun, 2004 | Pubmed ID: 14970006 Compensatory Responses of Protein Import and Transcription Factor Expression in Mitochondrial DNA Defects American Journal of Physiology. Cell Physiology. Apr, 2004 | Pubmed ID: 14656719 Regulation of Mitochondrial Biogenesis in Muscle by Endurance Exercise Sports Medicine (Auckland, N.Z.). 2003 | Pubmed ID: 12959619 PPARgamma Coactivator-1alpha Expression During Thyroid Hormone- and Contractile Activity-induced Mitochondrial Adaptations American Journal of Physiology. Cell Physiology. Jun, 2003 | Pubmed ID: 12734114 Mitochondrial Biogenesis and the Role of the Protein Import Pathway Medicine and Science in Sports and Exercise. Jan, 2003 | Pubmed ID: 12544641 Plasticity of Skeletal Muscle Mitochondria in Response to Contractile Activity Experimental Physiology. Jan, 2003 | Pubmed ID: 12525859 Functional Consequences of Thyroid Hormone-induced Changes in the Mitochondrial Protein Import Pathway American Journal of Physiology. Endocrinology and Metabolism. Jan, 2003 | Pubmed ID: 12388124 Apoptosis in Heart and Skeletal Muscle Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquee. Aug, 2002 | Pubmed ID: 12442352 Измерение способности митохондрий скелетных мышц импортировать белок Ashley N. Oliveira1, Brandon J. Richards1, David A. Hood1 1Muscle Health Research Center, School of Kinesiology and Health Science, York University JoVE 63055 Biochemistry
Измерение способности митохондрий скелетных мышц импортировать белок Ashley N. Oliveira1, Brandon J. Richards1, David A. Hood1 1Muscle Health Research Center, School of Kinesiology and Health Science, York University JoVE 63055 Biochemistry