Donald J. Buchsbaum Radiation Oncology University of Alabama at Birmingham Biography Publications Institution JoVE Articles Donald J. Buchsbaum has not added a biography. If you are Donald J. Buchsbaum and would like to personalize this page please email our Author Liaison for assistance. Publications S100A4 Promotes Pancreatic Cancer Progression Through a Dual Signaling Pathway Mediated by Src and Focal Adhesion Kinase Scientific Reports. 2015 | Pubmed ID: 25677816 Ovarian Cancer Stem Cells: Can Targeted Therapy Lead to Improved Progression-free Survival? World Journal of Stem Cells. Sep, 2014 | Pubmed ID: 25258665 Combination Therapy with Anti-DR5 Antibody and Tamoxifen for Triple Negative Breast Cancer Cancer Biology & Therapy. Aug, 2014 | Pubmed ID: 25084100 Pazopanib Combined with Radiation: in Vivo Model of Interaction Cancer Biotherapy & Radiopharmaceuticals. Aug, 2014 | Pubmed ID: 24945464 Recurrent Read-through Fusion Transcripts in Breast Cancer Breast Cancer Research and Treatment. Jul, 2014 | Pubmed ID: 24929677 Inhibition of Wnt/β-catenin Pathway by Niclosamide: a Therapeutic Target for Ovarian Cancer Gynecologic Oncology. Jul, 2014 | Pubmed ID: 24736023 Multi-targeted Therapy of Cancer by Niclosamide: A New Application for an Old Drug Cancer Letters. Jul, 2014 | Pubmed ID: 24732808 Effect of Niclosamide on Basal-like Breast Cancers Molecular Cancer Therapeutics. Apr, 2014 | Pubmed ID: 24552774 Will Detection of MicroRNA Biomarkers in Blood Improve the Diagnosis and Survival of Patients with Pancreatic Cancer? JAMA. Jan 22-29, 2014 | Pubmed ID: 24449314 Monoclonal Antibody-based Immunotherapy of Ovarian Cancer: Targeting Ovarian Cancer Cells with the B7-H3-specific MAb 376.96 Gynecologic Oncology. Jan, 2014 | Pubmed ID: 24216048 Antagonistic Effects of Anti-EMMPRIN Antibody when Combined with Chemotherapy Against Hypovascular Pancreatic Cancers Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2014 | Pubmed ID: 23836505 The Wnt/β-catenin Pathway in Ovarian Cancer: a Review Gynecologic Oncology. Dec, 2013 | Pubmed ID: 24125749 Catalase Abrogates β-lapachone-induced PARP1 Hyperactivation-directed Programmed Necrosis in NQO1-positive Breast Cancers Molecular Cancer Therapeutics. Oct, 2013 | Pubmed ID: 23883585 Lung Resistance-related Protein (LRP) Expression in Malignant Ascitic Cells As a Prognostic Marker for Advanced Ovarian Serous Carcinoma Annals of Surgical Oncology. Sep, 2013 | Pubmed ID: 23525731 The C-terminal Region Mesd Peptide Mimics Full-length Mesd and Acts As an Inhibitor of Wnt/β-catenin Signaling in Cancer Cells PloS One. 2013 | Pubmed ID: 23469146 ST6Gal-I Protein Expression is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines Cancer Research. Apr, 2013 | Pubmed ID: 23358684 Chapter Seven--Cancer Treatment with Gene Therapy and Radiation Therapy Advances in Cancer Research. 2012 | Pubmed ID: 23021246 A Review of B7-H3 and B7-H4 Immune Molecules and Their Role in Ovarian Cancer Gynecologic Oncology. Nov, 2012 | Pubmed ID: 22910694 A Deimmunized Bispecific Ligand-directed Toxin That Shows an Impressive Anti-pancreatic Cancer Effect in a Systemic Nude Mouse Orthotopic Model Pancreas. Jul, 2012 | Pubmed ID: 22258068 Progress in Cancer Therapy Cancer Biotherapy & Radiopharmaceuticals. Feb, 2012 | Pubmed ID: 22233333 The Impact of Novel Retinoids in Combination with Platinum Chemotherapy on Ovarian Cancer Stem Cells Gynecologic Oncology. Apr, 2012 | Pubmed ID: 22155260 The Use of Retinoids in Ovarian Cancer: a Review of the Literature International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Feb, 2012 | Pubmed ID: 22146768 Basal-like Breast Cancer Stem Cells Are Sensitive to Anti-DR5 Mediated Cytotoxicity Breast Cancer Research and Treatment. Jun, 2012 | Pubmed ID: 21915634 Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin PloS One. 2011 | Pubmed ID: 21935467 Relationship Between Galectin-3 Expression and TRAIL Sensitivity in Breast Cancer Expert Review of Anticancer Therapy. Aug, 2011 | Pubmed ID: 21916572 기저 같은 유방암에 안티-DR5 및 화학 요법의 효과 Breast Cancer Research and Treatment. Sep, 2011 | Pubmed ID: 21901385 Cisplatin 및 방사선 함께 TRA-8 작은 세포 폐 암 치료 Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011 | Pubmed ID: 21722984 Thrombospondin-1 Opens the Paracellular Pathway in Pulmonary Microvascular Endothelia Through EGFR/ErbB2 Activation American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2011 | Pubmed ID: 21531776 결합된 Cetuximab Irinotecan Orthotopic 췌 장 종양 Xenografts에 의해 동적 대비 향상 된 자기 공명 영상에서의 초기 치료 평가 Molecular Imaging. Jun, 2011 | Pubmed ID: 21496446 Mechanisms of Drug Sensitization to TRA-8, an Agonistic Death Receptor 5 Antibody, Involve Modulation of the Intrinsic Apoptotic Pathway in Human Breast Cancer Cells Molecular Cancer Research : MCR. Apr, 2011 | Pubmed ID: 21357440 Combined Modality Therapy with TRAIL or Agonistic Death Receptor Antibodies Cancer Biology & Therapy. Mar, 2011 | Pubmed ID: 21263219 Anti-tumor Activity of an Anti-DR5 Monoclonal Antibody, TRA-8, in Combination with Taxane/platinum-based Chemotherapy in an Ovarian Cancer Model Gynecologic Oncology. Apr, 2011 | Pubmed ID: 21211830 DCE MRI 유 방 종양 Xenografts 안티-DR5 치료에 따라 초기 혈관 반응 감지 Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2011 | Pubmed ID: 20383593 KISS1 Over-expression Suppresses Metastasis of Pancreatic Adenocarcinoma in a Xenograft Mouse Model Clinical & Experimental Metastasis. Dec, 2010 | Pubmed ID: 20844932 Overcoming TRAIL Resistance in Ovarian Carcinoma Gynecologic Oncology. Oct, 2010 | Pubmed ID: 20638107 A New Drug Delivery Method of Bispecific Ligand-directed Toxins, Which Reduces Toxicity and Promotes Efficacy in a Model of Orthotopic Pancreatic Cancer Pancreas. Aug, 2010 | Pubmed ID: 20182395 Monoclonal Antibodies in the Treatment of Pancreatic Cancer Immunotherapy. Mar, 2009 | Pubmed ID: 20046965 Experimental Cancer Therapy Using Restoration of NAD+ -linked 15-hydroxyprostaglandin Dehydrogenase Expression Molecular Cancer Therapeutics. Nov, 2009 | Pubmed ID: 19887544 Effect of TRA-8 Anti-death Receptor 5 Antibody in Combination with Chemotherapy in an Ex Vivo Human Ovarian Cancer Model International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Jul, 2009 | Pubmed ID: 19574765 Anti-EMMPRIN Monoclonal Antibody As a Novel Agent for Therapy of Head and Neck Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009 | Pubmed ID: 19509148 Polyethylene Glycosylated Curcumin Conjugate Inhibits Pancreatic Cancer Cell Growth Through Inactivation of Jab1 Molecular Pharmacology. Jul, 2009 | Pubmed ID: 19395473 Preclinical Studies and Clinical Utilization of Monoclonal Antibodies in Epithelial Ovarian Cancer Gynecologic Oncology. Jun, 2009 | Pubmed ID: 19232697 In Vivo Efficacy of Marimastat and Chemoradiation in Head and Neck Cancer Xenografts ORL; Journal for Oto-rhino-laryngology and Its Related Specialties. 2009 | Pubmed ID: 18931526 5 결합 된 Anti-death 수용 체 항 체 및 보급이 중 자기 공명 화상 진 찰에 의해 Orthotopic 췌 장 종양 Xenografts에 Gemcitabine 초기 치료 평가 Cancer Research. Oct, 2008 | Pubmed ID: 18922909 Molecular Chemotherapy of Pancreatic Cancer Using Novel Mutant Bacterial Cytosine Deaminase Gene Molecular Cancer Therapeutics. Sep, 2008 | Pubmed ID: 18790765 Molecular Targeted Therapies for Pancreatic Cancer American Journal of Surgery. Sep, 2008 | Pubmed ID: 18718222 Combination of Treatment with Death Receptor 5-specific Antibody with Therapeutic HPV DNA Vaccination Generates Enhanced Therapeutic Anti-tumor Effects Vaccine. Aug, 2008 | Pubmed ID: 18598733 Enhancement of Glioma Radiotherapy and Chemotherapy Response with Targeted Antibody Therapy Against Death Receptor 5 International Journal of Radiation Oncology, Biology, Physics. Jun, 2008 | Pubmed ID: 18474311 인간의 대 장 암 Xenografts TRA-8 Anti-death 수용 체 5 항 체 혼자 또는 함께 CPT 11의 치료 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2008 | Pubmed ID: 18381960 Anti-tumor Activity of the TRA-8 Anti-DR5 Antibody in Combination with Cisplatin in an Ex Vivo Human Cervical Cancer Model Gynecologic Oncology. Mar, 2008 | Pubmed ID: 18177927 TRA 8 안티-DR5 단일 클론 항 체 및 Gemcitabine Apoptosis 유도 및 Radiologically 유효한 Orthotopic 췌 장 종양 성장을 억제 Molecular Cancer Therapeutics. Dec, 2007 | Pubmed ID: 18089714 EGFR Genomic Gain and Aberrant Pathway Signaling in Pancreatic Cancer Patients The Journal of Surgical Research. Nov, 2007 | Pubmed ID: 17950068 Brief Overview of Preclinical and Clinical Studies in the Development of Intraperitoneal Radioimmunotherapy for Ovarian Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2007 | Pubmed ID: 17875801 죽음 5 수용 체 항 체와 CPT 11 안티 TRA 8 조합 치료는 췌장암의 Orthotopic 모델에서 종양 회귀를 유도합니다 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2007 | Pubmed ID: 17875786 TRAIL-receptor Antibodies As a Potential Cancer Treatment Future Oncology (London, England). Aug, 2007 | Pubmed ID: 17661715 Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Its Therapeutic Potential in Breast and Gynecologic Cancers Gynecologic Oncology. Sep, 2007 | Pubmed ID: 17602728 ErbB3 Expression and Dimerization with EGFR Influence Pancreatic Cancer Cell Sensitivity to Erlotinib Cancer Biology & Therapy. Apr, 2007 | Pubmed ID: 17457047 Pancreatic Cancer Epidermal Growth Factor Receptor (EGFR) Intron 1 Polymorphism Influences Postoperative Patient Survival and in Vitro Erlotinib Response Annals of Surgical Oncology. Jul, 2007 | Pubmed ID: 17453292 Epidermal Growth Factor Receptor (EGFR) is Highly Conserved in Pancreatic Cancer Surgery. Apr, 2007 | Pubmed ID: 17383523 고해상도 단일 광자 방출 단층 촬영을 계산 하 고 X-선 단층 촬영 영상에서 유 방 종양 Xenografts 99 M T C 표시 된 안티-DR5 항 체의 계산 Molecular Cancer Therapeutics. Mar, 2007 | Pubmed ID: 17363481 Efficacy of Anti-death Receptor 5 (DR5) Antibody (TRA-8) Against Primary Human Ovarian Carcinoma Using a Novel Ex Vivo Tissue Slice Model Gynecologic Oncology. May, 2007 | Pubmed ID: 17303227 Oncolytic HSV-1 for the Treatment of Brain Tumours Herpes : the Journal of the IHMF. Nov, 2006 | Pubmed ID: 17147910 Treatment with Gemcitabine and TRA-8 Anti-death Receptor-5 MAb Reduces Pancreatic Adenocarcinoma Cell Viability in Vitro and Growth in Vivo Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Nov, 2006 | Pubmed ID: 17114015 Pretargeted Radioimmunotherapy International Journal of Radiation Oncology, Biology, Physics. 2006 | Pubmed ID: 16979441 TRAIL Receptor-targeted Therapy Future Oncology (London, England). Aug, 2006 | Pubmed ID: 16922616 Multiple Gene Expression Analyses in Paraffin-embedded Tissues by TaqMan Low-density Array: Application to Hedgehog and Wnt Pathway Analysis in Ovarian Endometrioid Adenocarcinoma The Journal of Molecular Diagnostics : JMD. Feb, 2006 | Pubmed ID: 16436637 Gene Delivery and Gene Therapy of Prostate Cancer Expert Opinion on Drug Delivery. Jan, 2006 | Pubmed ID: 16370939 Anti-tumor Activity of TRA-8 Anti-death Receptor 5 (DR5) Monoclonal Antibody in Combination with Chemotherapy and Radiation Therapy in a Cervical Cancer Model Gynecologic Oncology. Apr, 2006 | Pubmed ID: 16271751 Antitumor Efficacy of Capecitabine and Celecoxib in Irradiated and Lead-shielded, Contralateral Human BxPC-3 Pancreatic Cancer Xenografts: Clinical Implications of Abscopal Effects Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2005 | Pubmed ID: 16361565 Intraperitoneal Pretarget Radioimmunotherapy CC49 퓨전 단백질으로 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2005 | Pubmed ID: 16299250 Intraperitoneal Radioimmunotherapy with a Humanized Anti-TAG-72 (CC49) Antibody with a Deleted CH2 Region Cancer Biotherapy & Radiopharmaceuticals. Oct, 2005 | Pubmed ID: 16248766 작은 열 충격 단백질 알파 B Crystallin는 Caspase 3의 활성화를 억제 하는 트레일 유도 Apoptosis의 비 발한 억제제 The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15653686 Radiotargeted 유전자 치료입니다 Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2005 | Pubmed ID: 15653667 Mechanisms of Resistance to Erbitux (anti-epidermal Growth Factor Receptor) Combination Therapy in Pancreatic Adenocarcinoma Cells Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Dec, 2004 | Pubmed ID: 15585383 Adenovirus-mediated FLT1-targeted Proapoptotic Gene Therapy of Human Prostate Cancer Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2004 | Pubmed ID: 15564138 Site-specifically Traced Drug Release and Biodistribution of a Paclitaxel-antibody Conjugate Toward Improvement of the Linker Structure Bioconjugate Chemistry. Nov-Dec, 2004 | Pubmed ID: 15546192 진 식 영상 방사선된 펩 티 드와 함께입니다 Annals of Nuclear Medicine. Jun, 2004 | Pubmed ID: 15359919 Anti-EGFR-mediated Radiosensitization As a Result of Augmented EGFR Expression International Journal of Radiation Oncology, Biology, Physics. 2004 | Pubmed ID: 15142629 Adenoviral Vector-mediated Augmentation of Epidermal Growth Factor Receptor (EGFr) Enhances the Radiosensitization Properties of Anti-EGFr Treatment in Prostate Cancer Cells International Journal of Radiation Oncology, Biology, Physics. Mar, 2004 | Pubmed ID: 14967455 Imaging and Therapy of Tumors Induced to Express Somatostatin Receptor by Gene Transfer Using Radiolabeled Peptides and Single Chain Antibody Constructs Seminars in Nuclear Medicine. Jan, 2004 | Pubmed ID: 14735457 Antitumor Efficacy of TRA-8 Anti-DR5 Monoclonal Antibody Alone or in Combination with Chemotherapy And/or Radiation Therapy in a Human Breast Cancer Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2003 | Pubmed ID: 14506165 Differential Responses by Pancreatic Carcinoma Cell Lines to Prolonged Exposure to Erbitux (IMC-C225) Anti-EGFR Antibody The Journal of Surgical Research. May, 2003 | Pubmed ID: 12850474 Three-dimensional Dose Model for the Comparison of 177Lu-HuCC49DeltaCH2 and 177Lu-HuCC49 Radioimunotherapy in Mice Bearing Intraperitoneal Xenografts Cancer Biotherapy & Radiopharmaceuticals. Apr, 2003 | Pubmed ID: 12804050 Synthesis and Biological Evaluation of Paclitaxel-C225 Conjugate As a Model for Targeted Drug Delivery Bioconjugate Chemistry. Mar-Apr, 2003 | Pubmed ID: 12643740 Invited Commentary: Targeting of 125I-labeled B Lymphocyte Stimulator Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Mar, 2003 | Pubmed ID: 12621011 An Adenovirus Encoding Proapoptotic Bax Synergistically Radiosensitizes Malignant Glioma International Journal of Radiation Oncology, Biology, Physics. Mar, 2003 | Pubmed ID: 12605984 Induction of Thymidine Phosphorylase in Both Irradiated and Shielded, Contralateral Human U87MG Glioma Xenografts: Implications for a Dual Modality Treatment Using Capecitabine and Irradiation Molecular Cancer Therapeutics. Oct, 2002 | Pubmed ID: 12481438 Treatment of Pancreatic Cancer Xenografts with Erbitux (IMC-C225) Anti-EGFR Antibody, Gemcitabine, and Radiation International Journal of Radiation Oncology, Biology, Physics. Nov, 2002 | Pubmed ID: 12419447 Adenovirus-mediated Transfer of BAX Driven by the Vascular Endothelial Growth Factor Promoter Induces Apoptosis in Lung Cancer Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2002 | Pubmed ID: 12161185 감마 카메라 듀얼 이미징 Somatostatin 수용 체와 티 미 딘 키 니 아와 쥐에 Bicistronic 아 데 노 바이러스와 유전자 이동 후 Radiology. May, 2002 | Pubmed ID: 11997547 Synthesis of the First Diethylenetriaminepentahydroxamic Acid (DTPH) Bifunctional Chelating Agent Bioconjugate Chemistry. Mar-Apr, 2002 | Pubmed ID: 11906271 De Novo Synthesis of a New Diethylenetriaminepentaacetic Acid (DTPA) Bifunctional Chelating Agent Bioconjugate Chemistry. Mar-Apr, 2002 | Pubmed ID: 11906270 Rationales, Evidence, and Design Considerations for Fractionated Radioimmunotherapy Cancer. Feb, 2002 | Pubmed ID: 11877764 [(90) Y]와 함께 방사선 치료를 대상으로-생쥐 인간 Nonsmall 세포 폐 종양 Xenografts 베어링에서 SMT 487 인간의 Somatostatin 수용 체의 하위 2 Adenoviral 벡터를 표현 하는 유도 Cancer. Feb, 2002 | Pubmed ID: 11877760 Model Prediction of Treatment Planning for Dose-fractionated Radioimmunotherapy Cancer. Feb, 2002 | Pubmed ID: 11877755 Intratumoral 5-fluorouracil Produced by Cytosine Deaminase/5-fluorocytosine Gene Therapy is Effective for Experimental Human Glioblastomas Cancer Research. Feb, 2002 | Pubmed ID: 11830532 Quantitation of Cytosine Deaminase MRNA by Real-time Reverse Transcription Polymerase Chain Reaction: a Sensitive Method for Assessing 5-fluorocytosine Toxicity in Vitro Analytical Biochemistry. Feb, 2002 | Pubmed ID: 11814289 동소 이식 췌장 암 마우스 모델의 동적 대비 강화 된 자기 공명 영상 Hyunki Kim1, Sharon Samuel1, John W. Totenhagen1, Marie Warren1, Jeffrey C. Sellers2, Donald J. Buchsbaum3 1Radiology, University of Alabama at Birmingham, 2Comprehensive Cancer Center, University of Alabama at Birmingham, 3Radiation Oncology, University of Alabama at Birmingham Medicine
동소 이식 췌장 암 마우스 모델의 동적 대비 강화 된 자기 공명 영상 Hyunki Kim1, Sharon Samuel1, John W. Totenhagen1, Marie Warren1, Jeffrey C. Sellers2, Donald J. Buchsbaum3 1Radiology, University of Alabama at Birmingham, 2Comprehensive Cancer Center, University of Alabama at Birmingham, 3Radiation Oncology, University of Alabama at Birmingham Medicine