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Articles by Erika Atucha in JoVE
JoVE Neuroscience
कृंतक Stereotaxic और व्यवहार Neuroscience के लिए सर्जरी पशु कल्याण परिणाम सुधार
1Department of Neuroscience, Section Anatomy, University Medical Center Groningen, University of Groningen, 2Animal Welfare Office, University of Groningen
कृन्तकों पर Stereotaxic सर्जरी दवाओं या बिजली की उत्तेजना और जाग में रिकॉर्डिंग, जानवरों के बर्ताव के लक्षित प्रशासन के लिए अनुमति देता है. इस वीडियो प्रस्तुति में हम हाल ही में प्रक्रियात्मक शोधन यह लंबे समय से चली आ रही प्रक्रिया है कि सफलतापूर्वक जीवित रहने की दर में सुधार और कम वजन हानि शल्य चिकित्सा के बाद करने के लिए प्रदर्शन करेंगे.
Other articles by Erika Atucha on PubMed
Structure-activity Relationship of Etomidate Derivatives at the GABA(A) Receptor: Comparison with Binding to 11beta-hydroxylase
At the GABA(A) receptor, low concentrations of etomidate potentiate the inhibitory effect of GABA on specific binding of the closed channel ligand [(3)H]ethynylpropylbicycloorthobenzoate ([(3)H]EBOB). Here, we present SARs for etomidate and structurally related compounds inducing this effect. In the absence of GABA, similar SARs, but 14-20 times weaker potencies were observed. We discuss these SARs in comparison to the much higher potencies of these compounds as inhibitors of 11beta-hydroxylase.
