Florian W. R. Vondran Department of General, Visceral and Transplant Surgery Hannover Medical School Biography Publications Institution JoVE Articles Florian W. R. Vondran has not added a biography. If you are Florian W. R. Vondran and would like to personalize this page please email our Author Liaison for assistance. Publications A Ribavirin-induced ORF2 Single-nucleotide Variant Produces Defective Hepatitis E Virus Particles with Immune Decoy Function Proceedings of the National Academy of Sciences of the United States of America. Aug, 2022 | Pubmed ID: 35969792 Identification of Structurally Re-engineered Rocaglates As Inhibitors Against Hepatitis E Virus Replication Antiviral Research. 08, 2022 | Pubmed ID: 35728703 Hypothermic Oxygenated Perfusion for Transplantation of a Pediatric Extended Right Lobe: Report of the First Case Transplantation. 06, 2022 | Pubmed ID: 35616916 Corrigendum To: 'Hepatocyte-specific Suppression of MicroRNA-221-3p Mitigates Liver Fibrosis' [J Hepatol (2019) 722-734] Journal of Hepatology. Jul, 2022 | Pubmed ID: 35397938 Corrigendum to 'Therapeutic HNF4A MRNA Attenuates Liver Fibrosis in a Preclinical Model' [J Hepatol (2021) 1420-1433] Journal of Hepatology. Jul, 2022 | Pubmed ID: 35397937 The Purinergic P2Y14 Receptor Links Hepatocyte Death to Hepatic Stellate Cell Activation and Fibrogenesis in the Liver Science Translational Medicine. 04, 2022 | Pubmed ID: 35385339 Impact of Perioperative Blood Transfusions on Postoperative Renal Function and Survival After Resection of Colorectal Liver Metastases World Journal of Surgical Oncology. Mar, 2022 | Pubmed ID: 35354485 Liver Transplantation After Organ Donation Due to Hydrogen Sulfide Intoxication: Report of the First Case Transplantation. 04, 2022 | Pubmed ID: 35333851 Cold Ischemia Time and Graft Fibrosis Are Associated with Autoantibodies After Pediatric Liver Transplantation: A Retrospective Cohort Study of the European Reference Network Children (Basel, Switzerland). Feb, 2022 | Pubmed ID: 35204995 Antibiotic-Resistant Bacteria Colonizing the Bile Duct Are Associated with Increased Morbidity and Mortality After Resection of Extrahepatic Cholangiocarcinoma Surgical Infections. Apr, 2022 | Pubmed ID: 35172114 Improved Alpharetrovirus-based Gag.MS2 Particles for Efficient and Transient Delivery of CRISPR-Cas9 into Target Cells Molecular Therapy. Nucleic Acids. Mar, 2022 | Pubmed ID: 35141043 Surgical Procedures in Patients Awaiting Liver Transplantation: Complications and Impact on the Liver Function Journal of Clinical and Experimental Hepatology. Jan-Feb, 2022 | Pubmed ID: 35068787 Outcome and Safety of a Surveillance Biopsy Guided Personalized Immunosuppression Program After Liver Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 02, 2022 | Pubmed ID: 34455702 Characterization of RNA Sensing Pathways in Hepatoma Cell Lines and Primary Human Hepatocytes Cells. 11, 2021 | Pubmed ID: 34831243 Proposal of a New Definition of "Very Early" Intrahepatic Cholangiocarcinoma-A Retrospective Single-Center Analysis Journal of Clinical Medicine. Sep, 2021 | Pubmed ID: 34575181 Therapeutic HNF4A MRNA Attenuates Liver Fibrosis in a Preclinical Model Journal of Hepatology. 12, 2021 | Pubmed ID: 34453962 BH3-only Protein Expression Determines Hepatocellular Carcinoma Response to Sorafenib-based Treatment Cell Death & Disease. 07, 2021 | Pubmed ID: 34312366 Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity Cells. 06, 2021 | Pubmed ID: 34209751 Liver-first Strategy for a Combined Lung and Liver Transplant in Patients with Cystic Fibrosis European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. 10, 2021 | Pubmed ID: 33956976 Direct Conversion of Porcine Primary Fibroblasts into Hepatocyte-like Cells Scientific Reports. 04, 2021 | Pubmed ID: 33927320 Initial HCV Infection of Adult Hepatocytes Triggers a Temporally Structured Transcriptional Program Containing Diverse Pro- and Anti-viral Elements Journal of Virology. Mar, 2021 | Pubmed ID: 33658347 Distinct Immune Imprints of Post-Liver Transplantation Hepatitis C Persist Despite Viral Clearance Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 06, 2021 | Pubmed ID: 33641215 Diaphragmatic Hernia Following Pediatric Liver Transplantation: An Underappreciated Complication Prone to Recur European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Fur Kinderchirurgie. Oct, 2021 | Pubmed ID: 33186999 Surgical Complications in Pediatric Kidney Transplantation-Incidence, Risk Factors, and Effects on Graft Survival: A Retrospective Single-center Study Pediatric Transplantation. 03, 2021 | Pubmed ID: 33053269 MicroRNA-125b-5p Regulates Hepatocyte Proliferation During the Termination Phase of Liver Regeneration Hepatology Communications. Dec, 2020 | Pubmed ID: 33305155 Liver-expressed and Limit Hepatitis C Virus Cross-species Transmission to Mice Science Advances. Nov, 2020 | Pubmed ID: 33148654 Longitudinal Imaging and Femtosecond Laser Manipulation of the Liver: How to Generate and Trace Single-cell-resolved Micro-damage in Vivo PloS One. 2020 | Pubmed ID: 33057345 Preoperative Leukocytosis and the Resection Severity Index Are Independent Risk Factors for Survival in Patients with Intrahepatic Cholangiocarcinoma Langenbeck's Archives of Surgery. Nov, 2020 | Pubmed ID: 32815017 Abdominal Surgery in Patients with Ventricular Assist Devices: a Single-Center Report ASAIO Journal (American Society for Artificial Internal Organs : 1992). 08, 2020 | Pubmed ID: 32740349 Therapeutic Plasma Exchange in Acute on Chronic Liver Failure Journal of Clinical Apheresis. Aug, 2020 | Pubmed ID: 32583446 The ATGL Lipase Cooperates with ABHD5 to Mobilize Lipids for Hepatitis C Virus Assembly PLoS Pathogens. 06, 2020 | Pubmed ID: 32542055 Hepatitis B Virus DNA is a Substrate for the CGAS/STING Pathway but is Not Sensed in Infected Hepatocytes Viruses. 05, 2020 | Pubmed ID: 32485908 The Importance of MHC Class II in Allogeneic Bone Marrow Transplantation and Chimerism-based Solid Organ Tolerance in a Rat Model PloS One. 2020 | Pubmed ID: 32442182 C19orf66 is an Interferon-induced Inhibitor of HCV Replication That Restricts Formation of the Viral Replication Organelle Journal of Hepatology. Apr, 2020 | Pubmed ID: 32294532 Long-term Functional Maintenance of Exteriorized Portal Venous Catheters in a Porcine Animal Model The Journal of Surgical Research. Mar, 2020 | Pubmed ID: 32163793 Efficient Acute and Chronic Infection of Stem Cell-derived Hepatocytes by Hepatitis C Virus Gut. Feb, 2020 | Pubmed ID: 32114504 Extended Hepatic Metastasectomy for Renal Cell Carcinoma-new Aspects in Times of Targeted Therapy: a Single-center Experience over Three Decades Langenbeck's Archives of Surgery. Feb, 2020 | Pubmed ID: 31938833 Robust Hepatitis E Virus Infection and Transcriptional Response in Human Hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31896581 A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection Antimicrobial Agents and Chemotherapy. 12, 2019 | Pubmed ID: 31658963 Recipient Natural Killer Cells Alter the Course of Rejection of Allogeneic Heart Grafts in Rats PloS One. 2019 | Pubmed ID: 31437165 Alloresponses of Mixed Lymphocyte Hepatocyte Culture to Immunosuppressive Drugs As an In-Vitro Model of Hepatocyte Transplantation Annals of Transplantation. Aug, 2019 | Pubmed ID: 31406101 Response to "Critical Appraisal of the Modified Ante Situm Liver Resection-is the Original Method the Better Choice?" Langenbeck's Archives of Surgery. 08, 2019 | Pubmed ID: 31256253 Identification of Keratin 23 As a Hepatitis C Virus-Induced Host Factor in the Human Liver Cells. 06, 2019 | Pubmed ID: 31216713 Silencing of HLA Class I on Primary Human Hepatocytes As a Novel Strategy for Reduction in Alloreactivity Journal of Cellular and Molecular Medicine. 08, 2019 | Pubmed ID: 31180181 Hepatocyte-specific Suppression of MicroRNA-221-3p Mitigates Liver Fibrosis Journal of Hepatology. 04, 2019 | Pubmed ID: 30582979 Use of Rotational Thromboelastometry in Liver Transplantation Is Associated With Reduced Transfusion Requirements Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. 04, 2019 | Pubmed ID: 30295585 T5 Exonuclease Hydrolysis of Hepatitis B Virus Replicative Intermediates Allows Reliable Quantification and Fast Drug Efficacy Testing of Covalently Closed Circular DNA by PCR Journal of Virology. Sep, 2018 | Pubmed ID: 30232183 Relevant Prognostic Factors Influencing Outcome of Patients After Surgical Resection of Distal Cholangiocarcinoma BMC Surgery. Aug, 2018 | Pubmed ID: 30103720 Interferon-beta Expression and Type I Interferon Receptor Signaling of Hepatocytes Prevent Hepatic Necrosis and Virus Dissemination in Coxsackievirus B3-infected Mice PLoS Pathogens. 08, 2018 | Pubmed ID: 30075026 Preoperative Recipient Parameters Allow Early Estimation of Postoperative Outcome and Intraoperative Transfusion Requirements in Liver Transplantation Progress in Transplantation (Aliso Viejo, Calif.). 06, 2018 | Pubmed ID: 29558874 Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes Gastroenterology. 06, 2018 | Pubmed ID: 29535029 Hepatitis D Virus Replication is Sensed by MDA5 and Induces IFN-β/λ Responses in Hepatocytes Journal of Hepatology. Jul, 2018 | Pubmed ID: 29524530 Modified Ante Situm Liver Resection Without Use of Cold Perfusion nor Veno-venous Bypass for Treatment of Hepatic Lesions Infiltrating the Hepatocaval Confluence Langenbeck's Archives of Surgery. May, 2018 | Pubmed ID: 29470630 Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an Infection Model Via NTCP-dependent Uptake of Enveloped Virus Particles Journal of Virology. Feb, 2018 | Pubmed ID: 29437961 Hepatitis E Virus Replication and Interferon Responses in Human Placental Cells Hepatology Communications. 02, 2018 | Pubmed ID: 29404525 Hepatocyte-induced CD4 T Cell Alloresponse is Associated with Major Histocompatibility Complex Class II Up-regulation on Hepatocytes and Suppressible by Regulatory T Cells Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 03, 2018 | Pubmed ID: 29365365 Myeloid Dendritic Cells Repress Human Cytomegalovirus Gene Expression and Spread by Releasing Interferon-Unrelated Soluble Antiviral Factors Journal of Virology. 01, 2018 | Pubmed ID: 29046460 Early Tracheostomy Reduces Time of Mechanical Ventilation in Respiratory High-Risk Patients After Liver Transplant Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. 10, 2018 | Pubmed ID: 29025380 Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy After Pre-operative Chemotherapy ANZ Journal of Surgery. Apr, 2018 | Pubmed ID: 28419692 Pentagalloylglucose, a Highly Bioavailable Polyphenolic Compound Present in Cortex Moutan, Efficiently Blocks Hepatitis C Virus Entry Antiviral Research. 11, 2017 | Pubmed ID: 28923507 Maturation of Secreted HCV Particles by Incorporation of Secreted ApoE Protects from Antibodies by Enhancing Infectivity Journal of Hepatology. Sep, 2017 | Pubmed ID: 28438690 Scavenger Receptor Class B Member 1 (SCARB1) Variants Modulate Hepatitis C Virus Replication Cycle and Viral Load Journal of Hepatology. 08, 2017 | Pubmed ID: 28363797 Sodium Taurocholate Cotransporting Polypeptide is the Limiting Host Factor of Hepatitis B Virus Infection in Macaque and Pig Hepatocytes Hepatology (Baltimore, Md.). 09, 2017 | Pubmed ID: 28195359 Tuning a Cellular Lipid Kinase Activity Adapts Hepatitis C Virus to Replication in Cell Culture Nature Microbiology. 12, 2016 | Pubmed ID: 27991882 Inactivation of HCV and HIV by Microwave: a Novel Approach for Prevention of Virus Transmission Among People Who Inject Drugs Scientific Reports. 11, 2016 | Pubmed ID: 27857152 Monitoring of Liver Function in a 73-year Old Patient Undergoing 'Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy': Case Report Applying the Novel Liver Maximum Function Capacity Test Patient Safety in Surgery. 2016 | Pubmed ID: 27293483 ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production PLoS Pathogens. 04, 2016 | Pubmed ID: 27124600 Immunological Aspects of Liver Cell Transplantation World Journal of Transplantation. Mar, 2016 | Pubmed ID: 27011904 Prediction of Survival and Tumor Recurrence in Patients Undergoing Surgery for Pancreatic Neuroendocrine Neoplasms Journal of Surgical Oncology. Feb, 2016 | Pubmed ID: 26709239 Flunarizine Prevents Hepatitis C Virus Membrane Fusion in a Genotype-dependent Manner by Targeting the Potential Fusion Peptide Within E1 Hepatology (Baltimore, Md.). Jan, 2016 | Pubmed ID: 26248546 Modulation of HCV Reinfection After Orthotopic Liver Transplantation by Fibroblast Growth Factor-2 and Other Non-interferon Mediators Gut. 06, 2016 | Pubmed ID: 25800783 Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses PloS One. 2015 | Pubmed ID: 26226615 Interferon-inducible Cholesterol-25-hydroxylase Restricts Hepatitis C Virus Replication Through Blockage of Membranous Web Formation Hepatology (Baltimore, Md.). Sep, 2015 | Pubmed ID: 25999047 Risk Factors for Short- and Long-term Mortality in Liver Transplant Recipients with MELD Score ≥30 Annals of Transplantation. Jan, 2015 | Pubmed ID: 25630462 Species-specific Regulation of Fibrinogen Synthesis with Implications for Porcine Hepatocyte Xenotransplantation Xenotransplantation. Sep-Oct, 2014 | Pubmed ID: 25175927 Explanted Diseased Livers - a Possible Source of Metabolic Competent Primary Human Hepatocytes PloS One. 2014 | Pubmed ID: 24999631 Helicobacter Hepaticus Induces an Inflammatory Response in Primary Human Hepatocytes PloS One. 2014 | Pubmed ID: 24932686 Pre-transplant Immune State Defined by Serum Markers and Alloreactivity Predicts Acute Rejection After Living Donor Kidney Transplantation Clinical Transplantation. Sep, 2014 | Pubmed ID: 24931031 Inhibition of Autophagic Flux by Salinomycin Results in Anti-cancer Effect in Hepatocellular Carcinoma Cells PloS One. 2014 | Pubmed ID: 24816744 The Clinically Approved Drugs Amiodarone, Dronedarone and Verapamil Inhibit Filovirus Cell Entry The Journal of Antimicrobial Chemotherapy. Aug, 2014 | Pubmed ID: 24710028 An Extended ΔCT-method Facilitating Normalisation with Multiple Reference Genes Suited for Quantitative RT-PCR Analyses of Human Hepatocyte-like Cells PloS One. 2014 | Pubmed ID: 24658132 Exchange of Cytosolic Content Between T Cells and Tumor Cells Activates CD4 T Cells and Impedes Cancer Growth PloS One. 2013 | Pubmed ID: 24205259 Autophagy Inhibition Due to Thymidine Analogues As Novel Mechanism Leading to Hepatocyte Dysfunction and Lipid Accumulation AIDS (London, England). Oct, 2012 | Pubmed ID: 22914580 Decreased Frequency of Peripheral CD4(+) CD161(+) Th(17) -precursor Cells in Kidney Transplant Recipients on Long-term Therapy with Belatacept Transplant International : Official Journal of the European Society for Organ Transplantation. Apr, 2012 | Pubmed ID: 22348376 Incidence and Outcome of Abdominal Surgical Interventions Following Lung Transplantation--a Single Center Experience Langenbeck's Archives of Surgery. Dec, 2011 | Pubmed ID: 21400068 Association of High Anti-donor Alloreactivity and Low Frequency of FoxP3-expressing Cells Prior to Kidney Transplantation with Acute Graft Rejection Clinical Transplantation. Nov-Dec, 2011 | Pubmed ID: 21070367 无静脉-静脉旁路术的猪肝移植作为扩展标准供体模型 Oliver Beetz*1, Felix Oldhafer*1, Clara A. Weigle1, Sebastian Cammann1, Daphne DeTemple1, Lion Sieg2, Hendrik Eismann2, Thomas Palmaers2, Florian W. R. Vondran1 1Department of General, Visceral and Transplant Surgery, Hannover Medical School, 2Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School JoVE 64152 Medicine
无静脉-静脉旁路术的猪肝移植作为扩展标准供体模型 Oliver Beetz*1, Felix Oldhafer*1, Clara A. Weigle1, Sebastian Cammann1, Daphne DeTemple1, Lion Sieg2, Hendrik Eismann2, Thomas Palmaers2, Florian W. R. Vondran1 1Department of General, Visceral and Transplant Surgery, Hannover Medical School, 2Department of Anaesthesiology and Intensive Care Medicine, Hannover Medical School JoVE 64152 Medicine