Henri G.D. Leuvenink Surgical Research Laboratory, Department of Surgery University of Groningen, University Medical Center Groningen Biography Publications Institution JoVE Articles Henri G.D. Leuvenink has not added a biography. If you are Henri G.D. Leuvenink and would like to personalize this page please email our Author Liaison for assistance. Publications Novel Organ Preservation Methods: Not Only Cool but Supercool! Transplantation. Apr, 2015 | Pubmed ID: 25827321 Hydrogen Sulfide in Renal Physiology, Disease and Transplantation--the Smell of Renal Protection Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Apr, 2015 | Pubmed ID: 25656225 Hydrogen Sulfide: Physiological Properties and Therapeutic Potential in Ischaemia British Journal of Pharmacology. Mar, 2015 | Pubmed ID: 25091411 Sodium Thiosulfate Attenuates Angiotensin II-induced Hypertension, Proteinuria and Renal Damage Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Nov, 2014 | Pubmed ID: 25459997 Hypoxia and Complement-and-Coagulation Pathways in the Deceased Organ Donor As the Major Target for Intervention to Improve Renal Allograft Outcome Transplantation. Nov, 2014 | Pubmed ID: 25427168 Criteria for Viability Assessment of Discarded Human Donor Livers During Ex Vivo Normothermic Machine Perfusion PloS One. 2014 | Pubmed ID: 25369327 Prednisolone Has a Positive Effect on the Kidney but Not on the Liver of Brain Dead Rats: a Potencial Role in Complement Activation Journal of Translational Medicine. 2014 | Pubmed ID: 24884924 Reply: To PMID 24355874 Journal of the American College of Surgeons. May, 2014 | Pubmed ID: 24745572 α-Melanocyte Stimulating Hormone Treatment in Pigs Does Not Improve Early Graft Function in Kidney Transplants from Brain Dead Donors PloS One. 2014 | Pubmed ID: 24728087 Histopathologic and Molecular Evaluation of the Organ Procurement and Transplantation Network Selection Criteria for Intestinal Graft Donation The Journal of Surgical Research. Jun, 2014 | Pubmed ID: 24655665 Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated After Circulatory Death PloS One. 2014 | Pubmed ID: 24551114 Early Angiopoietin-2 Levels After Onset Predict the Advent of Severe Pancreatitis, Multiple Organ Failure, and Infectious Complications in Patients with Acute Pancreatitis Journal of the American College of Surgeons. Jan, 2014 | Pubmed ID: 24355874 Erythropoietin-mediated Protection in Kidney Transplantation: Nonerythropoietic EPO Derivatives Improve Function Without Increasing Risk of Cardiovascular Events Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2014 | Pubmed ID: 23964738 Renoprotective Capacities of Non-erythropoietic EPO Derivative, ARA290, Following Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 24225194 Gaseous Hydrogen Sulfide Protects Against Myocardial Ischemia-reperfusion Injury in Mice Partially Independent from Hypometabolism PloS One. 2013 | Pubmed ID: 23675473 A Human Model of Intra-abdominal Hypertension: Even Slightly Elevated Pressures Lead to Increased Acute Systemic Inflammation and Signs of Acute Kidney Injury Critical Care (London, England). 2013 | Pubmed ID: 23566574 Nonesterified Fatty Acids and Development of Graft Failure in Renal Transplant Recipients Transplantation. Jun, 2013 | Pubmed ID: 23524974 Cystathionine γ-lyase Protects Against Renal Ischemia/reperfusion by Modulating Oxidative Stress Journal of the American Society of Nephrology : JASN. Apr, 2013 | Pubmed ID: 23449534 Are Brain and Heart Tissue Prone to the Development of Thiamine Deficiency? Alcohol (Fayetteville, N.Y.). May, 2013 | Pubmed ID: 23357554 Brain Death Induces Renal Expression of Heme Oxygenase-1 and Heat Shock Protein 70 Journal of Translational Medicine. 2013 | Pubmed ID: 23356498 SLC22A2 is Associated with Tubular Creatinine Secretion and Bias of Estimated GFR in Renal Transplantation Physiological Genomics. Mar, 2013 | Pubmed ID: 23341218 ARA290, a Non-erythropoietic EPO Derivative, Attenuates Renal Ischemia/reperfusion Injury Journal of Translational Medicine. 2013 | Pubmed ID: 23302512 UMOD As a Susceptibility Gene for End-stage Renal Disease BMC Medical Genetics. 2012 | Pubmed ID: 22947327 Beneficial Effects of Gaseous Hydrogen Sulfide in Hepatic Ischemia/reperfusion Injury Transplant International : Official Journal of the European Society for Organ Transplantation. Aug, 2012 | Pubmed ID: 22716165 CUBN As a Novel Locus for End-stage Renal Disease: Insights from Renal Transplantation PloS One. 2012 | Pubmed ID: 22574174 L'effet De La Recirculation Normothermique Avant Conservation Par Le Froid Sur Les Blessures Post-transplantation De Reins De Donneurs Ischémie Endommagés Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2012 | Pubmed ID: 22077364 Perfusion Machine Versus Cold Storage Pour La Préservation Des Reins De Donneurs Critères élargis Après La Mort Cérébrale Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2011 | Pubmed ID: 21332580 Préservation De L'intestin Grêle Pour Une Transplantation Intestinale: Un Examen Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2011 | Pubmed ID: 21083772 Quelle Est L'importance De La Durée De La Période De Mort Cérébrale Pour Le Résultat De La Transplantation Rénale? Transplant International : Official Journal of the European Society for Organ Transplantation. Jan, 2011 | Pubmed ID: 20819191 Perfusion Machine Versus Cold Storage Pour La Préservation Des Reins Donnés Après Un Arrêt Cardiaque: Une étude Multicentrique, Randomisée, Contrôlée Annals of Surgery. Nov, 2010 | Pubmed ID: 21037431 La Valeur Des Biomarqueurs Machine De Perfusion Perfusat Pour Prédire Des Résultats De Greffes De Reins Transplantation. Nov, 2010 | Pubmed ID: 20861807 Réduction D'ischémie-réoxygénation Des Blessures Dans L'intestin De Rat Après Conservation Luminal Une Solution Sur Mesure Transplantation. Sep, 2010 | Pubmed ID: 20689496 L'héparine Facteur De Croissance épidermique Dans Les Reliure Rénale Ischémie / Reperfusion The Journal of Pathology. Jun, 2010 | Pubmed ID: 20225242 Prétraitement Des Donateurs Avec L'érythropoïétine Carbamylée Dans Un Modèle De Mort Cérébrale Réduit L'inflammation Plus Efficacement Que L'érythropoïétine Tout En Préservant La Fonction Rénale Critical Care Medicine. Apr, 2010 | Pubmed ID: 20124889 Severe Thiamine Deficiency Complicated by Weight Loss Protects Against Renal Ischaemia-reperfusion Injury in Rats NDT Plus. Apr, 2009 | Pubmed ID: 25949326 L'influence De L'âge Du Donneur Décédé Et Du Vieux-pour-âge Répartition Sur Les Résultats De Greffes De Reins Transplantation. Aug, 2009 | Pubmed ID: 19696638 De La Perméabilité Intestinale Chez Le Rat Cerveau Décédés Morts Transplantation. Aug, 2009 | Pubmed ID: 19667953 Hydrogen Sulfide-induced Hypometabolism Prevents Renal Ischemia/reperfusion Injury Journal of the American Society of Nephrology : JASN. Sep, 2009 | Pubmed ID: 19628669 The Goddess of the Waters Kidney International. Apr, 2009 | Pubmed ID: 19337215 Perfusion Machine Ou Cold Storage Dans Provenant De Donneurs Décédés Transplantation De Rein The New England Journal of Medicine. Jan, 2009 | Pubmed ID: 19118301 Détérioration De La Fonction Musculaire Des Cellules Endothéliales Et Lisse Dans Les Reins DCD Après Cold Storage Statique Dans IGL-1 Ou UW The Journal of Surgical Research. Apr, 2009 | Pubmed ID: 18701116 Mort Cérébrale Induit Une Inflammation Dans L'intestin Des Donateurs Transplantation. Jul, 2008 | Pubmed ID: 18622292 Les événements Précoces De Don D'un Rein: Progression De L'activation Endothéliale, Le Stress Oxydatif Et Des Blessures Tubulaire Après La Mort Cérébrale American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. May, 2008 | Pubmed ID: 18318776 Préservation Statique Entreposage à Froid Des Reins Endommagés Ischémie. Une Comparaison Entre IGL-1 Et La Solution UW Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2008 | Pubmed ID: 18225993 Amélioration De La Fonction Du Greffon Rénal Après Préservation L'aide D'un Nouveau Dispositif De Perfusion Hypothermique Machine Annals of Surgery. Dec, 2007 | Pubmed ID: 18043100 Le Modèle Apparition Progressive Mort Cérébrale: Un Modèle Pertinent D'étudier Le Don D'organes Et De Ses Conséquences Sur Le Résultat Après La Transplantation Laboratory Animals. Jul, 2007 | Pubmed ID: 17640464 Perspectives En Matière De Préservation D'organes Transplantation. May, 2007 | Pubmed ID: 17519776 Tissue Thiamine Deficiency As Potential Cause of Delayed Graft Function After Kidney Transplantation: Thiamine Supplementation of Kidney Donors May Improve Transplantation Outcome Medical Hypotheses. 2007 | Pubmed ID: 17379423 Détermination D'une Pression De Perfusion Adéquate Pour Perfusion Continue Navire Machine Double Hypothermique Du Foie De Rat Transplant International : Official Journal of the European Society for Organ Transplantation. Apr, 2007 | Pubmed ID: 17326775 Non-coeur Le Don D'organes Battement: Perspectives Et Avenir Aperçu Transplant International : Official Journal of the European Society for Organ Transplantation. Jul, 2007 | Pubmed ID: 17263786 Expression Spatio-temporelle De L'hème Oxygénase-1 Détecté Par Bioluminescence in Vivo Après Une Ischémie Hépatique Chez La Souris HO-1/Luc Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2006 | Pubmed ID: 17058249 Hémodilution Isovolémique Aiguë Déclencheurs Pro-inflammatoire Et Procoagulant Activation Endothéliale Dans Les Organes Vitaux: Rôle De L'agrégation érythrocytaire Microcirculation (New York, N.Y. : 1994). Jul-Aug, 2006 | Pubmed ID: 16815825 Les Doses D'érythropoïétine Ou Cytoprotecteurs érythropoïétine Carbamylée Ont Nettement Différentes Activités Procoagulantes Et Vasoactif Proceedings of the National Academy of Sciences of the United States of America. Apr, 2006 | Pubmed ID: 16585502 Hepatic Expression of ABC Transporters G5 and G8 Does Not Correlate with Biliary Cholesterol Secretion in Liver Transplant Patients Hepatology (Baltimore, Md.). Nov, 2005 | Pubmed ID: 16250035 Oxygénation Pendant La Préservation De Foie De Rat En Hypothermie: Une étude in Vitro Trancher Pour Démontrer Les Effets Bénéfiques Ou Toxiques Oxygénation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2005 | Pubmed ID: 16237692 Expression of Heme Oxygenase-1 in Human Livers Before Transplantation Correlates with Graft Injury and Function After Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2005 | Pubmed ID: 15996234 Rapid Increase of Bile Salt Secretion is Associated with Bile Duct Injury After Human Liver Transplantation Journal of Hepatology. Dec, 2004 | Pubmed ID: 15582136 Distinct Changements Transcriptionnels Dans Les Reins Des Donneurs Lors De L'induction De Mort Cérébrale Chez Le Rat: Le Point Dans Les Processus De La Mort Cérébrale American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2004 | Pubmed ID: 15575899 Effet De La Mort Cérébrale Sur L'expression Génique Et D'activation Dans Les Tissus Des Reins De Donneurs De L'homme Transplantation. Oct, 2004 | Pubmed ID: 15480162 Délavage Sang Initiale Au Cours Organ Procurement Détermine Lésions Hépatiques Et Fonction Après La Préservation Et La Reperfusion American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2004 | Pubmed ID: 15476484 Effet De L'Université Du Wisconsin-Orgue De Conservation Solution Sur Haemorheology Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2004 | Pubmed ID: 15146313 Préservation Machine Hypothermique Dans La Transplantation Hépatique Revisited: Concepts Et Critères Dans Le Nouveau Millénaire Annals of Biomedical Engineering. Apr, 2004 | Pubmed ID: 15117035 Effet De La Mort Cérébrale Et La Non-coeur-coups De Rein De Donneur Sur La Fonction Rénale Et Des Blessures: Une évaluation Dans Le Rein De Rat Isolé Perfusé Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation. Dec, 2003 | Pubmed ID: 15859914 Macrophage Overgrowth Affects Neighboring Nonovergrown Encapsulated Islets The Journal of Surgical Research. Dec, 2003 | Pubmed ID: 14697289 Effective Removal of Alginate-poly-L-lysine Microcapsules from Pancreatic Islets by Use of Trypsin-EDTA Journal of Biomedical Materials Research. Part A. Nov, 2003 | Pubmed ID: 14566813 Relation Entre La Durée De La Mort Cérébrale Et Hémodynamique (in) Stabilité Sur La Dysfonction Progressive Et Activation Immunologique Accrue Des Reins De Donneurs Kidney International. Nov, 2003 | Pubmed ID: 14531823 Hyperaggregating Effet Des Composants Hydroxyéthylamidon, Et L'Université De Wisconsin Solution Sur Des Globules Rouges Humains: Un Risque De Perfusion Du Greffon Avec Facultés Affaiblies Au Organ Procurement? Transplantation. Jul, 2003 | Pubmed ID: 12865783 Ex Situ Normothermique machine perfusion de foies de donneurs Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine
Ex Situ Normothermique machine perfusion de foies de donneurs Negin Karimian1,2, Alix P.M. Matton1,2, Andrie C. Westerkamp1,2, Laura C. Burlage1,2, Sanna op den Dries1,2, Henri G.D. Leuvenink2, Ton Lisman1,2, Korkut Uygun3, James F. Markmann4, Robert J. Porte1,2 1Section of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, 2Surgical Research Laboratory, Department of Surgery, University of Groningen, University Medical Center Groningen, 3Center of Engineering in Medicine/Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Burns Hospital, 4Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 52688 Medicine