Hsuan Yu Chen Orthopaedic department NTUH Biography Publications Institution JoVE Articles Hsuan Yu ChenDoctor spine specialty Publications Childhood Acute Lymphoblastic Leukemia Mercaptopurine Intolerance is Associated with NUDT15 Variants Pediatric Research. Mar, 2020 | Pubmed ID: 32221476 Landscape of Mitochondria Genome and Clinical Outcomes in Stage 1 Lung Adenocarcinoma Cancers. Mar, 2020 | Pubmed ID: 32210009 TP53 Alterations in Relapsed Childhood Acute Lymphoblastic Leukemia Cancer Science. Jan, 2020 | Pubmed ID: 31729120 Impact of Cervical Sagittal Parameters and Spinal Cord Morphology in Cervical Spondylotic Myelopathy Status Post Spinous Process-splitting Laminoplasty European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. Dec, 2019 | Pubmed ID: 31834484 Results of Using Robotic-assisted Navigational System in Pedicle Screw Placement PloS One. Month, 2019 | Pubmed ID: 31425528 Characteristics of an Alternative Antibacterial Biomaterial for Mouthwash in the Absence of Alcohol Journal of Dental Sciences. Jun, 2019 | Pubmed ID: 31210893 Cranial Irradiation for Patients with Epidermal Growth Factor Receptor (EGFR) Mutant Lung Cancer Who Have Brain Metastases in the Era of a New Generation of EGFR Inhibitors The Oncologist. 12, 2019 | Pubmed ID: 31127020 Tumor Mutation Burden and Recurrent Tumors in Hereditary Lung Cancer Cancer Medicine. 05, 2019 | Pubmed ID: 30941903 Risk Factors Associated With Altered Circulating Micro RNA -125b And Their Influences on Uremic Vascular Calcification Among Patients With End-Stage Renal Disease Journal of the American Heart Association. 01, 2019 | Pubmed ID: 30646802 EGFR-Mutant SCLC Exhibits Heterogeneous Phenotypes and Resistance to Common Antineoplastic Drugs Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. 03, 2019 | Pubmed ID: 30521971 The Treatment of Chronic Radial Head Dislocation in Monteggia Fracture Without Annular Ligament Reconstruction International Orthopaedics. 09, 2018 | Pubmed ID: 29713746 EGFR Mutation, Smoking, and Gender in Advanced Lung Adenocarcinoma Oncotarget. Nov, 2017 | Pubmed ID: 29228697 FAM198B is Associated with Prolonged Survival and Inhibits Metastasis in Lung Adenocarcinoma Via Blockage of ERK-Mediated MMP-1 Expression Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2017 | Pubmed ID: 29217529 Differences in the Frequency of Alzheimer's Disease-associated Genomic Variations in Populations of Different Races Geriatrics & Gerontology International. Nov, 2017 | Pubmed ID: 28675603 Circulating MicroRNA-125b Predicts the Presence and Progression of Uremic Vascular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. 07, 2017 | Pubmed ID: 28522697 Cancer Cells Increase Endothelial Cell Tube Formation and Survival by Activating the PI3K/Akt Signalling Pathway Journal of Experimental & Clinical Cancer Research : CR. 02, 2017 | Pubmed ID: 28173828 Crosstalk Between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis Developmental Cell. 02, 2017 | Pubmed ID: 28171750 Turning Diversity Toward Precision Journal of the National Cancer Institute. Jan, 2017 | Pubmed ID: 28104780 Daxx Inhibits Hypoxia-induced Lung Cancer Cell Metastasis by Suppressing the HIF-1α/HDAC1/Slug Axis Nature Communications. 12, 2016 | Pubmed ID: 28004751 Variant and Medication Adherence in Predicting Response to Lithium Maintenance Treatment in Bipolar I Disorder BJPsych Open. Sep, 2016 | Pubmed ID: 27703793 Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death Through Interaction with Katanin Journal of Medicinal Chemistry. Sep, 2016 | Pubmed ID: 27536893 Implementation and Quality Control of Lung Cancer EGFR Genetic Testing by MALDI-TOF Mass Spectrometry in Taiwan Clinical Practice Scientific Reports. 08, 2016 | Pubmed ID: 27480787 Higher Frequency but Random Distribution of EGFR Mutation Subtypes in Familial Lung Cancer Patients Oncotarget. Aug, 2016 | Pubmed ID: 27449093 Molecular Gene Signature and Prognosis of Non-small Cell Lung Cancer Oncotarget. Aug, 2016 | Pubmed ID: 27437769 Oncogenic MiR-137 Contributes to Cisplatin Resistance Via Repressing CASP3 in Lung Adenocarcinoma American Journal of Cancer Research. Month, 2016 | Pubmed ID: 27429846 The Emergence of T790M Mutation in EGFR-mutant Lung Adenocarcinoma Patients Having a History of Acquired Resistance to EGFR-TKI: Focus on Rebiopsy Timing and Long-term Existence of T790M Oncotarget. Jul, 2016 | Pubmed ID: 27384480 SPANXA Suppresses EMT by Inhibiting C-JUN/SNAI2 Signaling in Lung Adenocarcinoma Oncotarget. Jul, 2016 | Pubmed ID: 27323831 JAG1 Is Associated with Poor Survival Through Inducing Metastasis in Lung Cancer PloS One. Month, 2016 | Pubmed ID: 26930648 Predilection of Contralateral Upper Lung Metastasis in Upper Lobe Lung Adenocarcinoma Patients Journal of Thoracic Disease. Jan, 2016 | Pubmed ID: 26904216 EPIANNO: EPIgenomics ANNOtation Tool PloS One. Month, 2016 | Pubmed ID: 26859295 EGFR-activating Mutations, DNA Copy Number Abundance of ErbB Family, and Prognosis in Lung Adenocarcinoma Oncotarget. Feb, 2016 | Pubmed ID: 26824984 Postoperative Showering for Clean and Clean-contaminated Wounds: A Prospective, Randomized Controlled Trial Annals of Surgery. May, 2016 | Pubmed ID: 26655923 EGFR Mutation and Lobar Location of Lung Adenocarcinoma Carcinogenesis. Feb, 2016 | Pubmed ID: 26645716 A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in T(12;21)-Positive Acute Lymphoblastic Leukemia PloS One. Month, 2015 | Pubmed ID: 26580398 Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression Scientific Reports. Sep, 2015 | Pubmed ID: 26399191 Apoptosis Pathway Signature for Prediction of Treatment Response and Clinical Outcome in Childhood High Risk B-Precursor Acute Lymphoblastic Leukemia American Journal of Cancer Research. Month, 2015 | Pubmed ID: 26175952 R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2015 | Pubmed ID: 26056182 Pathway-based Gene Signatures Predicting Clinical Outcome of Lung Adenocarcinoma Scientific Reports. Jun, 2015 | Pubmed ID: 26042604 HOXA5 Inhibits Metastasis Via Regulating Cytoskeletal Remodelling and Associates with Prolonged Survival in Non-small-cell Lung Carcinoma PloS One. Month, 2015 | Pubmed ID: 25875824 IL-8 Confers Resistance to EGFR Inhibitors by Inducing Stem Cell Properties in Lung Cancer Oncotarget. Apr, 2015 | Pubmed ID: 25871388 Large-scale Determination of Absolute Phosphorylation Stoichiometries in Human Cells by Motif-targeting Quantitative Proteomics Nature Communications. Mar, 2015 | Pubmed ID: 25814448 Identification of Five Driver Gene Mutations in Patients with Treatment-naïve Lung Adenocarcinoma in Taiwan PloS One. Month, 2015 | Pubmed ID: 25789627 Heparin Co-factor II Enhances Cell Motility and Promotes Metastasis in Non-small Cell Lung Cancer The Journal of Pathology. Jan, 2015 | Pubmed ID: 25130770 Use of Temperature and Humidity Sensors to Determine Moisture Content of Oolong Tea Sensors (Basel, Switzerland). Aug, 2014 | Pubmed ID: 25153142 Bcl-2-like Protein 11 Deletion Polymorphism Predicts Survival in Advanced Non-small-cell Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Sep, 2014 | Pubmed ID: 25057939 Prior EGFR Tyrosine-kinase Inhibitor Therapy Did Not Influence the Efficacy of Subsequent Pemetrexed Plus Platinum in Advanced Chemonaïve Patients with EGFR-mutant Lung Adenocarcinoma OncoTargets and Therapy. Month, 2014 | Pubmed ID: 24920920 MicroRNA-133a Suppresses Multiple Oncogenic Membrane Receptors and Cell Invasion in Non-small Cell Lung Carcinoma PloS One. Month, 2014 | Pubmed ID: 24816813 Cancer-associated Fibroblasts Regulate the Plasticity of Lung Cancer Stemness Via Paracrine Signalling Nature Communications. Mar, 2014 | Pubmed ID: 24668028 Inhibition of MiR-146a Prevents Enterovirus-induced Death by Restoring the Production of Type I Interferon Nature Communications. Month, 2014 | Pubmed ID: 24561744 Acute Thoracic Empyema: Clinical Characteristics and Outcome Analysis of Video-assisted Thoracoscopic Surgery Journal of the Formosan Medical Association = Taiwan Yi Zhi. Apr, 2014 | Pubmed ID: 24512757 MicroRNA-135b Promotes Lung Cancer Metastasis by Regulating Multiple Targets in the Hippo Pathway and LZTS1 Nature Communications. Month, 2013 | Pubmed ID: 23695671 The Motor Protein KIF14 Inhibits Tumor Growth and Cancer Metastasis in Lung Adenocarcinoma PloS One. Month, 2013 | Pubmed ID: 23626713 Genome-wide Analysis of Three-way Interplay Among Gene Expression, Cancer Cell Invasion and Anti-cancer Compound Sensitivity BMC Medicine. Apr, 2013 | Pubmed ID: 23590835 Reduction of the Domino Effect in Osteoporotic Vertebral Compression Fractures Through Short-segment Fixation with Intravertebral Expandable Pillars Compared to Percutaneous Kyphoplasty: a Case Control Study BMC Musculoskeletal Disorders. Mar, 2013 | Pubmed ID: 23452614 Absence of Biallelic TCRγ Deletion Predicts Induction Failure and Poorer Outcomes in Childhood T-cell Acute Lymphoblastic Leukemia Pediatric Blood & Cancer. Jun, 2012 | Pubmed ID: 22180181 Single-walled Carbon Nanotubes Induce Airway Hyperreactivity and Parenchymal Injury in Mice American Journal of Respiratory Cell and Molecular Biology. Feb, 2012 | Pubmed ID: 21960547 Admissions to Intensive Care Unit of HIV-infected Patients in the Era of Highly Active Antiretroviral Therapy: Etiology and Prognostic Factors Critical Care (London, England). Aug, 2011 | Pubmed ID: 21871086 Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-specific Antibodies and EGFR TKIs Response Prediction PloS One. Month, 2011 | Pubmed ID: 21858063 Clustered Genomic Alterations in Chromosome 7p Dictate Outcomes and Targeted Treatment Responses of Lung Adenocarcinoma with EGFR-activating Mutations Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2011 | Pubmed ID: 21810691 The Ability of LCRMP-1 to Promote Cancer Invasion by Enhancing Filopodia Formation is Antagonized by CRMP-1 The Journal of Clinical Investigation. Aug, 2011 | Pubmed ID: 21747164 IKZF1 Deletions Predict a Poor Prognosis in Children with B-cell Progenitor Acute Lymphoblastic Leukemia: a Multicenter Analysis in Taiwan Cancer Science. Oct, 2011 | Pubmed ID: 21740479 MicroRNA Expression Aberration As Potential Peripheral Blood Biomarkers for Schizophrenia PloS One. Month, 2011 | Pubmed ID: 21738743 Antitumor Agents 283. Further Elaboration of Desmosdumotin C Analogs As Potent Antitumor Agents: Activation of Spindle Assembly Checkpoint As Possible Mode of Action Bioorganic & Medicinal Chemistry. Mar, 2011 | Pubmed ID: 21296579 Enterovirus-induced MiR-141 Contributes to Shutoff of Host Protein Translation by Targeting the Translation Initiation Factor EIF4E Cell Host & Microbe. Jan, 2011 | Pubmed ID: 21238947 Multiplex Reverse Transcription-polymerase Chain Reaction As Diagnostic Molecular Screening of 4 Common Fusion Chimeric Genes in Taiwanese Children with Acute Lymphoblastic Leukemia Journal of Pediatric Hematology/oncology. Nov, 2010 | Pubmed ID: 20930648 Expression and Prognostic Significance of the Apoptotic Genes BCL2L13, Livin, and CASP8AP2 in Childhood Acute Lymphoblastic Leukemia Leukemia Research. Jan, 2010 | Pubmed ID: 20109966 Tumor Size Matters Differently in Pulmonary Adenocarcinoma and Squamous Cell Carcinoma Lung Cancer (Amsterdam, Netherlands). Mar, 2010 | Pubmed ID: 19473720 Phenanthrene-based Tylophorine-1 (PBT-1) Inhibits Lung Cancer Cell Growth Through the Akt and NF-kappaB Pathways Journal of Medicinal Chemistry. Apr, 2009 | Pubmed ID: 19284764 MicroRNA-18a Prevents Estrogen Receptor-alpha Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells Gastroenterology. Feb, 2009 | Pubmed ID: 19027010 Bone Marrow Angiogenesis Magnetic Resonance Imaging in Patients with Acute Myeloid Leukemia: Peak Enhancement Ratio is an Independent Predictor for Overall Survival Blood. Apr, 2009 | Pubmed ID: 18988863 Intra-abdominal Adhesion Formation Induces Anti-oxidative Injury, Enhances Cell Proliferation, and Prevents Complement-mediated Lysis Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. May-Jun, 2008 | Pubmed ID: 18471257 MicroRNA Signature Predicts Survival and Relapse in Lung Cancer Cancer Cell. Jan, 2008 | Pubmed ID: 18167339 TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer American Journal of Respiratory and Critical Care Medicine. Apr, 2008 | Pubmed ID: 18096709 Unique MicroRNA Signature and Clinical Outcome of Cancers DNA and Cell Biology. May, 2007 | Pubmed ID: 17504024 A Five-gene Signature and Clinical Outcome in Non-small-cell Lung Cancer The New England Journal of Medicine. Jan, 2007 | Pubmed ID: 17202451 Topology-based Cancer Classification and Related Pathway Mining Using Microarray Data Nucleic Acids Research. Month, 2006 | Pubmed ID: 16914437 CRSD: a Comprehensive Web Server for Composite Regulatory Signature Discovery Nucleic Acids Research. Jul, 2006 | Pubmed ID: 16845073 A New Tumor Suppressor DnaJ-like Heat Shock Protein, HLJ1, and Survival of Patients with Non-small-cell Lung Carcinoma Journal of the National Cancer Institute. Jun, 2006 | Pubmed ID: 16788156 Gene Expression Profiles in Hypoxic Preconditioning Using CDNA Microarray Analysis: Altered Expression of an Angiogenic Factor, Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 Shock (Augusta, Ga.). Aug, 2005 | Pubmed ID: 16044082 Arsenic Suppresses Gene Expression in Promyelocytic Leukemia Cells Partly Through Sp1 Oxidation Blood. Jul, 2005 | Pubmed ID: 15761015 A Spine Robotic-Assisted Navigation System for Pedicle Screw Placement Hsuan-Yu Chen1,2,3, Xiu-Yun Xiao4, Chih-Wei Chen1,4, Hao-Kai Chou1,4, Chen-Yu Sung4, Feng Huei Lin1, Po-Quang Chen2, Tze-hong Wong2 1Institute of Biomedical Engineering, National Taiwan University, 2Department of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Branch, 3Department of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Biomedical Park Branch, 4Point Robotics MedTech Inc. JoVE 60924 Bioengineering
A Spine Robotic-Assisted Navigation System for Pedicle Screw Placement Hsuan-Yu Chen1,2,3, Xiu-Yun Xiao4, Chih-Wei Chen1,4, Hao-Kai Chou1,4, Chen-Yu Sung4, Feng Huei Lin1, Po-Quang Chen2, Tze-hong Wong2 1Institute of Biomedical Engineering, National Taiwan University, 2Department of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Branch, 3Department of Orthopedic Surgery, National Taiwan University Hospital, Hsin-Chu Biomedical Park Branch, 4Point Robotics MedTech Inc. JoVE 60924 Bioengineering
