In-Hyun Park Yale Stem Cell Center, Department of Genetics Yale School of Medicine Biography Publications Institution JoVE Articles In-Hyun Park has not added a biography. If you are In-Hyun Park and would like to personalize this page please email our Author Liaison for assistance. Publications Mutant Induced Pluripotent Stem Cell Lines Recapitulate Aspects of TDP-43 Proteinopathies and Reveal Cell-specific Vulnerability Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22451909 Overcoming Reprogramming Resistance of Fanconi Anemia Cells Blood. Feb, 2012 | Pubmed ID: 22371882 Humanized Murine Model for HBV and HCV Using Human Induced Pluripotent Stem Cells Archives of Pharmacal Research. Feb, 2012 | Pubmed ID: 22370780 Human Induced Pluripotent Stem Cells and Neurodegenerative Disease: Prospects for Novel Therapies Current Opinion in Neurology. Apr, 2012 | Pubmed ID: 22357218 The Lesser Known Story of X Chromosome Reactivation: a Closer Look into the Reprogramming of the Inactive X Chromosome Cell Cycle (Georgetown, Tex.). Jan, 2012 | Pubmed ID: 22234239 Screening Ethnically Diverse Human Embryonic Stem Cells Identifies a Chromosome 20 Minimal Amplicon Conferring Growth Advantage Nature Biotechnology. Dec, 2011 | Pubmed ID: 22119741 Cell Cycle Adaptations of Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22084091 Research Highlights Regenerative Medicine. Nov, 2011 | Pubmed ID: 22050520 Neuronal Maturation Defect in Induced Pluripotent Stem Cells from Patients with Rett Syndrome Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21807996 Induced Pluripotent Stem Cell Models from X-linked Adrenoleukodystrophy Patients Annals of Neurology. Sep, 2011 | Pubmed ID: 21721033 Transplantation of Adult Mouse IPS Cell-derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice PloS One. 2011 | Pubmed ID: 21559507 Induced Pluripotent Stem Cells for Neural Tissue Engineering Biomaterials. Aug, 2011 | Pubmed ID: 21514663 Stage-specific Signaling Through TGFβ Family Members and WNT Regulates Patterning and Pancreatic Specification of Human Pluripotent Stem Cells Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21270052 Induced Pluripotent Stem Cells: a Novel Frontier in the Study of Human Primary Immunodeficiencies The Journal of Allergy and Clinical Immunology. Jun, 2011 | Pubmed ID: 21185069 Analysis of Differential Proteomes of Induced Pluripotent Stem Cells by Protein-based Reprogramming of Fibroblasts Journal of Proteome Research. Mar, 2011 | Pubmed ID: 21175196 Hematopoietic Differentiation of Induced Pluripotent Stem Cells from Patients with Mucopolysaccharidosis Type I (Hurler Syndrome) Blood. Jan, 2011 | Pubmed ID: 21037085 Human Pluripotent Stem Cells Produce Natural Killer Cells That Mediate Anti-HIV-1 Activity by Utilizing Diverse Cellular Mechanisms Journal of Virology. Jan, 2011 | Pubmed ID: 20962093 MicroRNA Profiling Reveals Two Distinct P53-related Human Pluripotent Stem Cell States Cell Stem Cell. Dec, 2010 | Pubmed ID: 21112562 Large Intergenic Non-coding RNA-RoR Modulates Reprogramming of Human Induced Pluripotent Stem Cells Nature Genetics. Dec, 2010 | Pubmed ID: 21057500 Five Classic Articles in Somatic Cell Reprogramming The Yale Journal of Biology and Medicine. Sep, 2010 | Pubmed ID: 20885901 Research Highlights Regenerative Medicine. Jul, 2010 | Pubmed ID: 20632853 Reprogramming of T Cells from Human Peripheral Blood Cell Stem Cell. Jul, 2010 | Pubmed ID: 20621044 Robust Enhancement of Neural Differentiation from Human ES and IPS Cells Regardless of Their Innate Difference in Differentiation Propensity Stem Cell Reviews. Jun, 2010 | Pubmed ID: 20376579 Telomere Elongation in Induced Pluripotent Stem Cells from Dyskeratosis Congenita Patients Nature. Mar, 2010 | Pubmed ID: 20164838 DYS-HAC-iPS Cells: the Combination of Gene and Cell Therapy to Treat Duchenne Muscular Dystrophy Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2010 | Pubmed ID: 20125163 Directed Differentiation of Hematopoietic Precursors and Functional Osteoclasts from Human ES and IPS Cells Blood. Apr, 2010 | Pubmed ID: 20065292 Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells Hepatology (Baltimore, Md.). Jan, 2010 | Pubmed ID: 19877180 A Robust Approach to Identifying Tissue-specific Gene Expression Regulatory Variants Using Personalized Human Induced Pluripotent Stem Cells PLoS Genetics. Nov, 2009 | Pubmed ID: 19911041 Differential Methylation of Tissue- and Cancer-specific CpG Island Shores Distinguishes Human Induced Pluripotent Stem Cells, Embryonic Stem Cells and Fibroblasts Nature Genetics. Dec, 2009 | Pubmed ID: 19881528 Live Cell Imaging Distinguishes Bona Fide Human IPS Cells from Partially Reprogrammed Cells Nature Biotechnology. Nov, 2009 | Pubmed ID: 19826408 Hematopoietic Development from Human Induced Pluripotent Stem Cells Annals of the New York Academy of Sciences. Sep, 2009 | Pubmed ID: 19796250 Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells Circulation. Oct, 2009 | Pubmed ID: 19786631 A Role for Lin28 in Primordial Germ-cell Development and Germ-cell Malignancy Nature. Aug, 2009 | Pubmed ID: 19578360 Gene Targeting of a Disease-related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells Cell Stem Cell. Jul, 2009 | Pubmed ID: 19540188 Down's Syndrome Suppression of Tumour Growth and the Role of the Calcineurin Inhibitor DSCR1 Nature. Jun, 2009 | Pubmed ID: 19458618 Targeted Bisulfite Sequencing Reveals Changes in DNA Methylation Associated with Nuclear Reprogramming Nature Biotechnology. Apr, 2009 | Pubmed ID: 19330000 Targeted and Genome-scale Strategies Reveal Gene-body Methylation Signatures in Human Cells Nature Biotechnology. Apr, 2009 | Pubmed ID: 19329998 Generation of Induced Pluripotent Stem Cells from Human Blood Blood. May, 2009 | Pubmed ID: 19299331 Human IPS Cell Derivation/reprogramming Current Protocols in Stem Cell Biology. Jan, 2009 | Pubmed ID: 19170021 Regulatory Networks Define Phenotypic Classes of Human Stem Cell Lines Nature. Sep, 2008 | Pubmed ID: 18724358 Disease-specific Induced Pluripotent Stem Cells Cell. Sep, 2008 | Pubmed ID: 18691744 Generation of Human-induced Pluripotent Stem Cells Nature Protocols. 2008 | Pubmed ID: 18600223 Reprogramming of Human Somatic Cells to Pluripotency with Defined Factors Nature. Jan, 2008 | Pubmed ID: 18157115 Debugging Cellular Reprogramming Nature Cell Biology. Aug, 2007 | Pubmed ID: 17671453 In Vitro Generation of Germ Cells from Murine Embryonic Stem Cells Nature Protocols. 2006 | Pubmed ID: 17487192 A Nuclear Transport Signal in Mammalian Target of Rapamycin is Critical for Its Cytoplasmic Signaling to S6 Kinase 1 The Journal of Biological Chemistry. Mar, 2006 | Pubmed ID: 16407298 Mammalian Target of Rapamycin (mTOR) Signaling is Required for a Late-stage Fusion Process During Skeletal Myotube Maturation The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 16043480 Skeletal Myocyte Hypertrophy Requires MTOR Kinase Activity and S6K1 Experimental Cell Research. Sep, 2005 | Pubmed ID: 15963500 IGF-II Transcription in Skeletal Myogenesis is Controlled by MTOR and Nutrients The Journal of Cell Biology. Dec, 2003 | Pubmed ID: 14662739 PLD1 Regulates MTOR Signaling and Mediates Cdc42 Activation of S6K1 Current Biology : CB. Dec, 2003 | Pubmed ID: 14653992 Regulation of Ribosomal S6 Kinase 2 by Mammalian Target of Rapamycin The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12087098 Omprogrammering Menneskelige Somatiske celler i Utførte pluripotent stamceller (iPSCs) Bruke retrovirale Vector med GFP Kun-Yong Kim1, Eriona Hysolli1, In-Hyun Park1 1Yale Stem Cell Center, Department of Genetics, Yale School of Medicine JoVE 3804 Biology
Omprogrammering Menneskelige Somatiske celler i Utførte pluripotent stamceller (iPSCs) Bruke retrovirale Vector med GFP Kun-Yong Kim1, Eriona Hysolli1, In-Hyun Park1 1Yale Stem Cell Center, Department of Genetics, Yale School of Medicine JoVE 3804 Biology