Ingeborg Friehs Department of Cardiac Surgery, Boston Children’s Hospital Harvard Medical School Biography Publications Institution JoVE Articles Ingeborg Friehs has not added a biography. If you are Ingeborg Friehs and would like to personalize this page please email our Author Liaison for assistance. Publications Case Report: Active Clinical Manifestation of Endocardial Fibroelastosis in Adolescence in a Patient with Mitral and Aortic Obstruction-histologic Presence of Endothelial-to-mesenchymal Transformation Frontiers in Cardiovascular Medicine. 2022 | Pubmed ID: 36531727 Endothelial-to-Mesenchymal Transition As Underlying Mechanism for the Formation of Double-Chambered Right Ventricle Pediatric Cardiology. Jun, 2022 | Pubmed ID: 35084525 Mechanical Strain Triggers Endothelial-to-mesenchymal Transition of the Endocardium in the Immature Heart Pediatric Research. Sep, 2022 | Pubmed ID: 34837068 Human Endothelial Colony-forming Cells Provide Trophic Support for Pluripotent Stem Cell-derived Cardiomyocytes Via Distinctively High Expression of Neuregulin-1 Angiogenesis. Jan, 2021 | Pubmed ID: 33454888 Autogenous Mitochondria Transplantation for Treatment of Right Heart Failure The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020 | Pubmed ID: 32919774 Flow Disturbances and the Development of Endocardial Fibroelastosis The Journal of Thoracic and Cardiovascular Surgery. Feb, 2020 | Pubmed ID: 31668539 Flow Disturbances and Progression of Endocardial Fibroelastosis - a Case Report Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Sep - Oct, 2019 | Pubmed ID: 31150840 Alloreactivity and Allorecognition of Syngeneic and Allogeneic Mitochondria Mitochondrion. 05, 2019 | Pubmed ID: 29588218 A Growth-Accommodating Implant for Paediatric Applications Nature Biomedical Engineering. 2017 | Pubmed ID: 29900036 Treating a 20 Mm Hg Gradient Alleviates Myocardial Hypertrophy in Experimental Aortic Coarctation The Journal of Surgical Research. Oct, 2017 | Pubmed ID: 28985849 Vascular Endothelial Growth Factor Prevents Endothelial-to-Mesenchymal Transition In Hypertrophy The Annals of Thoracic Surgery. Sep, 2017 | Pubmed ID: 28483153 Myocardial Rescue with Autologous Mitochondrial Transplantation in a Porcine Model of Ischemia/reperfusion The Journal of Thoracic and Cardiovascular Surgery. 04, 2017 | Pubmed ID: 27938904 Pilomotor Function is Impaired in Patients with Parkinson's Disease: A Study of the Adrenergic Axon-reflex Response and Autonomic Functions Parkinsonism & Related Disorders. Oct, 2016 | Pubmed ID: 27569843 Development of a Vascularized Heterotopic Neonatal Rat Heart Transplantation Model European Surgical Research. Europaische Chirurgische Forschung. Recherches Chirurgicales Europeennes. 2016 | Pubmed ID: 27544776 Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection PloS One. 2016 | Pubmed ID: 27500955 A Light-reflecting Balloon Catheter for Atraumatic Tissue Defect Repair Science Translational Medicine. Sep, 2015 | Pubmed ID: 26400910 Distention of the Immature Left Ventricle Triggers Development of Endocardial Fibroelastosis: An Animal Model of Endocardial Fibroelastosis Introducing Morphopathological Features of Evolving Fetal Hypoplastic Left Heart Syndrome BioMed Research International. 2015 | Pubmed ID: 26064914 Endocardial Fibroelastosis is Caused by Aberrant Endothelial to Mesenchymal Transition Circulation Research. Feb, 2015 | Pubmed ID: 25587097 Pressure Overload Induces IL-18 and IL-18R Expression, but Markedly Suppresses IL-18BP Expression in a Rabbit Model. IL-18 Potentiates TNF-α-induced Cardiomyocyte Death Journal of Molecular and Cellular Cardiology. Oct, 2014 | Pubmed ID: 25108227 A Blood-resistant Surgical Glue for Minimally Invasive Repair of Vessels and Heart Defects Science Translational Medicine. Jan, 2014 | Pubmed ID: 24401941 Pressione Sovraccarico Ipertrofia Del Cuore in Via Di Sviluppo Rivela L'attivazione Di Percorsi Divergenti Di Gene E Proteina Nel Miocardio Ventricolare Destra E Sinistro American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2013 | Pubmed ID: 23262132 A Highly Tunable Biocompatible and Multifunctional Biodegradable Elastomer Advanced Materials (Deerfield Beach, Fla.). Feb, 2013 | Pubmed ID: 23239051 An Animal Model of Endocardial Fibroelastosis The Journal of Surgical Research. Jun, 2013 | Pubmed ID: 22938709 Inibitori Endogeni Dell'angiogenesi Impediscono Adattivo Crescita Capillare Nella Ipertrofia Di Sovraccarico Di Pressione Ventricolare Sinistra The Annals of Thoracic Surgery. Nov, 2012 | Pubmed ID: 22795062 Up-regulation of Soluble Vascular Endothelial Growth Factor Receptor-1 Prevents Angiogenesis in Hypertrophied Myocardium Cardiovascular Research. Feb, 2011 | Pubmed ID: 20935166 Electron Transport Chain Dysfunction in Neonatal Pressure-overload Hypertrophy Precedes Cardiomyocyte Apoptosis Independent of Oxidative Stress The Journal of Thoracic and Cardiovascular Surgery. Jun, 2010 | Pubmed ID: 20038480 Sviluppo Di Disfunzione Diastolica Ventricolare Sinistra Con Conservazione Della Frazione Di Eiezione Durante La Progressione Dell'ipertrofia Ventricolare Destra Infantile Circulation. Heart Failure. Nov, 2009 | Pubmed ID: 19919985 Del Miocita Apoptosi Si Verifica Precocemente Durante Lo Sviluppo Di Pressione-sovraccarico Ipertrofia Nel Miocardio Infantile The Journal of Thoracic and Cardiovascular Surgery. Jun, 2009 | Pubmed ID: 19464448 Proteasome Inhibition in Hypertrophied Myocardium American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008 | Pubmed ID: 18708439 Inhibition of Glycogen Synthase Kinase-3beta Improves Tolerance to Ischemia in Hypertrophied Hearts The Annals of Thoracic Surgery. Jul, 2007 | Pubmed ID: 17588398 Age-dependent Expression of VEGF Isoforms and Receptors in the Rabbit Anterior Cruciate Ligament Biochimica Et Biophysica Acta. Jul, 2007 | Pubmed ID: 17459591 Dopamina Induce Postischemic Cardiomyocyte Apoptosis in Vivo: Un Effetto Migliorata Da Propofol The Annals of Thoracic Surgery. Dec, 2006 | Pubmed ID: 17126134 Vascular Endothelial Growth Factor Prevents Apoptosis and Preserves Contractile Function in Hypertrophied Infant Heart Circulation. Jul, 2006 | Pubmed ID: 16820588 Conduzione Cardiaca Attraverso Il Tessuto Ingegnerizzato The American Journal of Pathology. Jul, 2006 | Pubmed ID: 16816362 Vascular Endothelial Growth Factor Delays Onset of Failure in Pressure-overload Hypertrophy Through Matrix Metalloproteinase Activation and Angiogenesis Basic Research in Cardiology. May, 2006 | Pubmed ID: 16369727 Ciclosporina A, Ma Non FK-506 Protegge Dall'apoptosi Indotta Da Dopamina Nel Cuore Stordito The Annals of Thoracic Surgery. May, 2005 | Pubmed ID: 15854943 Impaired Insulin-signaling in Hypertrophied Hearts Contributes to Ischemic Injury Biochemical and Biophysical Research Communications. May, 2005 | Pubmed ID: 15845351 Promuovere L'angiogenesi Protegge Cuori Gravemente Ipertrofici Da Lesione Ischemica The Annals of Thoracic Surgery. Jun, 2004 | Pubmed ID: 15172254 Postnatale Aumento Di Espressione Del Trasportatore Di Glucosio Insulino-sensibili è Associata Con Una Migliore Recupero Della Funzione Miocardica Postischemic The Journal of Thoracic and Cardiovascular Surgery. Jul, 2003 | Pubmed ID: 12878964 Valutazione Non Invasiva Seriale Della Meccanica Del Miocardio in Pressione Sovraccarico Ipertrofia Del Miocardio Di Coniglio Herz. Feb, 2003 | Pubmed ID: 12616321 Increased Susceptibility of Hypertrophied Hearts to Ischemic Injury The Annals of Thoracic Surgery. Feb, 2003 | Pubmed ID: 12607712 Improving Results of the Modified Fontan Operation in Patients with Heterotaxy Syndrome The Annals of Thoracic Surgery. Dec, 2002 | Pubmed ID: 12643382 Trattamento Della Dopamina Di Disfunzione Contrattile Postischemic Induce Rapidamente Signaling Pro-apoptotic Calcio-dipendente Circulation. Sep, 2002 | Pubmed ID: 12354748 Effetti Protettivi Della Chinasi Di Proteina C Durante L'ischemia Del Miocardio Richiedono L'attivazione Di Fosfatidil-inositolo Specifiche Fosfolipasi C The Annals of Thoracic Surgery. Apr, 2002 | Pubmed ID: 11998814 Outcome After Reconstruction of Discontinuous Pulmonary Arteries The Journal of Thoracic and Cardiovascular Surgery. Feb, 2002 | Pubmed ID: 11828283 A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition (Video) | JoVE Gregor Gierlinger1, Lavinia Rech1, Sitaram M. Emani1, Pedro J. del Nido1, Ingeborg Friehs1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 65426 Medicine
A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition (Video) | JoVE Gregor Gierlinger1, Lavinia Rech1, Sitaram M. Emani1, Pedro J. del Nido1, Ingeborg Friehs1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 65426 Medicine