J. Steven Alexander

Publications

• Three-dimensional Printing of Bioactive Hernia Meshes: In vitro Proof of Principle
  Surgery. Oct, 2016  |   Pubmed ID: 27726915
• Hydrogen Sulfide Metabolism Regulates Endothelial Solute Barrier Function
  Redox Biology. Oct, 2016  |   Pubmed ID: 27552214
• From Trash to Treasure: The Untapped Potential of Endothelial Microparticles in Neurovascular Diseases
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Aug, 2016  |   Pubmed ID: 27531185
• Sulforaphane Induces Neurovascular Protection Against a Systemic Inflammatory Challenge Via Both Nrf2-dependent and Independent Pathways
  Vascular Pharmacology. Oct, 2016  |   Pubmed ID: 27401964
• Substitution with Alternative Anti-TNFα Therapy (SAVANT)-Outcomes of a Crohn's Disease Cohort Undergoing Substitution Therapy with Certolizumab
  Inflammatory Bowel Diseases. Jun, 2016  |   Pubmed ID: 27104819
• 1,25(OH)2D3 Induces Placental Vascular Smooth Muscle Cell Relaxation by Phosphorylation of Myosin Phosphatase Target Subunit 1Ser507: Potential Beneficial Effects of Vitamin D on Placental Vasculature in Humans
  Biology of Reproduction. May, 2016  |   Pubmed ID: 27075619
• "Microglial Nodules" and "newly Forming Lesions" May Be a Janus Face of Early MS Lesions; Implications from Virus-induced Demyelination, the Inside-Out Model
  BMC Neurology. Oct, 2015  |   Pubmed ID: 26499989
• Evidence for Nontraditional Lymphatics in the Choroid
  Investigative Ophthalmology & Visual Science. Feb, 2015  |   Pubmed ID: 26241180
• Dual Signals Underlying Diabetic Lymphatic Barrier Dysregulation
  Cardiovascular Research. Jul, 2015  |   Pubmed ID: 25994173
• Distinct Kinetics of Viral Replication, T Cell Infiltration, and Fibrosis in Three Phases of Myocarditis Following Theiler's Virus Infection
  Cellular Immunology. Nov-Dec, 2014  |   Pubmed ID: 25460083
• Preface of the Special Issue - "Africa"
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2014  |   Pubmed ID: 25236675
• Bioinformatics Multivariate Analysis Determined a Set of Phase-specific Biomarker Candidates in a Novel Mouse Model for Viral Myocarditis
  Circulation. Cardiovascular Genetics. Aug, 2014  |   Pubmed ID: 25031303
• Photothermolysis of Lymphatic Endothelial Cells by Gold Nanoshell-mediated Hyperthermia
  Journal of Nanoscience and Nanotechnology. Jul, 2014  |   Pubmed ID: 24758030
• Improved Wound Healing of Postischemic Cutaneous Flaps with the Use of Bone Marrow-derived Stem Cells
  The Laryngoscope. Mar, 2014  |   Pubmed ID: 23818296
• Role of Chymase in Preeclampsia
  Current Vascular Pharmacology. Sep, 2013  |   Pubmed ID: 24063379
• VEGF-A Isoform Modulation in an Preclinical TNBS Model of Ulcerative Colitis: Protective Effects of a VEGF164b Therapy
  Journal of Translational Medicine. Sep, 2013  |   Pubmed ID: 24020796
• A Recombinant Inhibitory Isoform of Vascular Endothelial Growth Factor164/165 Aggravates Ischemic Brain Damage in a Mouse Model of Focal Cerebral Ischemia
  The American Journal of Pathology. Sep, 2013  |   Pubmed ID: 23906811
• Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-mediated Transport of HDL
  Cell Metabolism. May, 2013  |   Pubmed ID: 23663736
• Does Pelvic Mesh Treated with Phosphorylcholine Improve Outcomes? An Early Experience
  European Journal of Obstetrics, Gynecology, and Reproductive Biology. Apr, 2013  |   Pubmed ID: 23280282
• Acute Carbonyl Stress Induces Occludin Glycation and Brain Microvascular Endothelial Barrier Dysfunction: Role for Glutathione-dependent Metabolism of Methylglyoxal
  Free Radical Biology & Medicine. Jan, 2013  |   Pubmed ID: 23108103
• Enhancing the Adhesion of Hematopoietic Precursor Cell Integrins with Hydrogen Peroxide Increases Recruitment Within Murine Gut
  Cell Transplantation. 2013  |   Pubmed ID: 22889470
• Immunopathological Patterns from EAE and Theiler's Virus Infection: Is Multiple Sclerosis a Homogenous 1-stage or Heterogenous 2-stage Disease?
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22633747
• Angiopoietins As Promising Biomarkers and Potential Therapeutic Targets in Brain Injury
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22633746
• Introduction: Brain Injury
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2013  |   Pubmed ID: 22503573
• Emerging Roles of Endothelial Cells in Multiple Sclerosis Pathophysiology and Therapy
  Neurological Research. Oct, 2012  |   Pubmed ID: 22828184
• Plasma Ubiquitin-proteasome System Profile in Patients with Multiple Sclerosis: Correlation with Clinical Features, Neuroimaging, and Treatment with Interferon-beta-1b
  Neurological Research. Jul, 2012  |   Pubmed ID: 22709658
• Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
  International Journal of Cell Biology. 2012  |   Pubmed ID: 22505936
• Rapamycin Inhibits Lymphatic Endothelial Cell Tube Formation by Downregulating Vascular Endothelial Growth Factor Receptor 3 Protein Expression
  Neoplasia (New York, N.Y.). Mar, 2012  |   Pubmed ID: 22496622
• Interferon-beta-1b Protects Against Multiple Sclerosis-induced Endothelial Cells Apoptosis
  Frontiers in Bioscience (Elite Edition). Jan, 2012  |   Pubmed ID: 22201961
• Gliovascular and Cytokine Interactions Modulate Brain Endothelial Barrier in Vitro
  Journal of Neuroinflammation. Nov, 2011  |   Pubmed ID: 22112345
• Synergistic Effect of Resveratrol and Quercetin Released from Drug-eluting Polymer Coatings for Endovascular Devices
  Journal of Biomedical Materials Research. Part B, Applied Biomaterials. Nov, 2011  |   Pubmed ID: 21948767
• Cryptotanshinone Inhibits Lymphatic Endothelial Cell Tube Formation by Suppressing VEGFR-3/ERK and Small GTPase Pathways
  Cancer Prevention Research (Philadelphia, Pa.). Dec, 2011  |   Pubmed ID: 21881029
• Analysis of Endothelial Barrier Function in Vitro
  Methods in Molecular Biology (Clifton, N.J.). 2011  |   Pubmed ID: 21874457
• Complement in Neurobiology
  Frontiers in Bioscience (Landmark Edition). Jun, 2011  |   Pubmed ID: 21622213
• The Effects of High Dose Interferon-β1a on Plasma Microparticles: Correlation with MRI Parameters
  Journal of Neuroinflammation. May, 2011  |   Pubmed ID: 21554694
• Role of the Endothelium in Inflammatory Bowel Diseases
  World Journal of Gastroenterology. Feb, 2011  |   Pubmed ID: 21350707
• Selectin-mediated Recruitment of Bone Marrow Stromal Cells in the Postischemic Cerebral Microvasculature
  Stroke; a Journal of Cerebral Circulation. Mar, 2011  |   Pubmed ID: 21257828
• Multiple Sclerosis and Cerebral Endothelial Dysfunction: Mechanisms
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Feb, 2011  |   Pubmed ID: 20663648
• Murine RVEGF164b, an Inhibitory VEGF Reduces VEGF-A-dependent Endothelial Proliferation and Barrier Dysfunction
  Microcirculation (New York, N.Y. : 1994). Oct, 2010  |   Pubmed ID: 21040119
• Emerging Roles of Lymphatics in Inflammatory Bowel Disease
  Annals of the New York Academy of Sciences. Oct, 2010  |   Pubmed ID: 20961310
• VEGF₁₆₄ Differentially Regulates Neutrophil and T Cell Adhesion Through ItgaL- and ItgaM-dependent Mechanisms
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2010  |   Pubmed ID: 20884890
• Analysis of in Vitro Transfection by Sonoporation Using Cationic and Neutral Microbubbles
  Ultrasound in Medicine & Biology. Nov, 2010  |   Pubmed ID: 20800945
• Elevated Plasma Chymotrypsin-like Protease (chymase) Activity in Women with Preeclampsia
  Hypertension in Pregnancy. 2010  |   Pubmed ID: 20670150
• Induction of Neuro-protective/regenerative Genes in Stem Cells Infiltrating Post-ischemic Brain Tissue
  Experimental & Translational Stroke Medicine. May, 2010  |   Pubmed ID: 20509949
• Alemtuzumab and Multiple Sclerosis: Therapeutic Application
  Expert Opinion on Biological Therapy. Mar, 2010  |   Pubmed ID: 20095876
• Editorial: Lymphatic Vessel Functions in Health and Disease
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Sep, 2010  |   Pubmed ID: 20005084
• Angiopoietin-2 in Experimental Colitis
  Inflammatory Bowel Diseases. Jun, 2010  |   Pubmed ID: 19902545
• Potential Roles of Cell-derived Microparticles in Ischemic Brain Disease
  Neurological Research. Oct, 2009  |   Pubmed ID: 19723448
• Chymotrypsin-like Protease (chymase) Mediates Endothelial Activation by Factors Derived from Preeclamptic Placentas
  Reproductive Sciences (Thousand Oaks, Calif.). Sep, 2009  |   Pubmed ID: 19494363
• Placenta-derived Chymotrypsin-like Protease (CLP) Disturbs Endothelial Junctional Structure in Preeclampsia
  Reproductive Sciences (Thousand Oaks, Calif.). May, 2009  |   Pubmed ID: 19126871
• Isotope Tracing Enhancement of Chemiluminescence Assays for Nitric Oxide Research
  Biological Chemistry. Feb, 2009  |   Pubmed ID: 19040352
• Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Glutamate/MK-801: Significance in Ischemic Stroke Injury
  Journal of Molecular Neuroscience : MN. Jun, 2009  |   Pubmed ID: 18843451
• Evidence of Platelet Activation in Multiple Sclerosis
  Journal of Neuroinflammation. Jun, 2008  |   Pubmed ID: 18588683
• NeuroAIDS: Characteristics and Diagnosis of the Neurological Complications of AIDS
  Molecular Diagnosis & Therapy. 2008  |   Pubmed ID: 18288880
• Combination Therapy with Interferon Beta-1a and Doxycycline in Multiple Sclerosis: an Open-label Trial
  Archives of Neurology. Feb, 2008  |   Pubmed ID: 18071030
• Clinical and Neuroimaging Correlates of Antiphospholipid Antibodies in Multiple Sclerosis: a Preliminary Study
  BMC Neurology. Oct, 2007  |   Pubmed ID: 17945023
• Proteomic Analysis of Human Cerebral Endothelial Cells Activated by Multiple Sclerosis Serum and IFNbeta-1b
  Journal of Molecular Neuroscience : MN. 2007  |   Pubmed ID: 17873362
• Inflammatory Cytokines Induce MAdCAM-1 in Murine Hepatic Endothelial Cells and Mediate Alpha-4 Beta-7 Integrin Dependent Lymphocyte Endothelial Adhesion in Vitro
  BMC Physiology. Sep, 2007  |   Pubmed ID: 17868448
• HIV Antiretroviral Drug Combination Induces Endothelial Mitochondrial Dysfunction and Reactive Oxygen Species Production, but Not Apoptosis
  Toxicology and Applied Pharmacology. Oct, 2007  |   Pubmed ID: 17669453
• Platelet-associated NAD(P)H Oxidase Contributes to the Thrombogenic Phenotype Induced by Hypercholesterolemia
  Free Radical Biology & Medicine. Jul, 2007  |   Pubmed ID: 17561090
• Evolving Therapies for Multiple Sclerosis
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531859
• Cell-derived Microparticles and Exosomes in Neuroinflammatory Disorders
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531844
• The Destructive Alliance: Interactions of Leukocytes, Cerebral Endothelial Cells, and the Immune Cascade in Pathogenesis of Multiple Sclerosis
  International Review of Neurobiology. 2007  |   Pubmed ID: 17531835
• CD40-CD40 Ligand Mediates the Recruitment of Leukocytes and Platelets in the Inflamed Murine Colon
  Gastroenterology. Mar, 2007  |   Pubmed ID: 17324402
• Multiple Sclerosis As a Vascular Disease
  Neurological Research. Apr, 2006  |   Pubmed ID: 16687046
• Expression of Lymphatic Vascular Endothelial Hyaluronan Receptor-1 (LYVE-1) in the Human Placenta
  Lymphatic Research and Biology. 2006  |   Pubmed ID: 16569201
• Insulin Prevents Oxidant-induced Endothelial Cell Barrier Dysfunction Via Nitric Oxide-dependent Pathway
  Surgery. Jan, 2006  |   Pubmed ID: 16364721
• VEGF-A Stimulation of Leukocyte Adhesion to Colonic Microvascular Endothelium: Implications for Inflammatory Bowel Disease
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2006  |   Pubmed ID: 16293653
• Apolipoprotein A-IV Attenuates Oxidant-induced Apoptosis in Mitotic Competent, Undifferentiated Cells by Modulating Intracellular Glutathione Redox Balance
  American Journal of Physiology. Cell Physiology. Jan, 2006  |   Pubmed ID: 16120654
• Effects of Peroxynitrite and Superoxide Radicals on Endothelial Monolayer Permeability: Potential Role of Peroxynitrite in Preeclampsia
  Journal of the Society for Gynecologic Investigation. Dec, 2005  |   Pubmed ID: 16325748
• The Role of Alpha-4 Integrin in the Aetiology of Multiple Sclerosis: Current Knowledge and Therapeutic Implications
  CNS Drugs. 2005  |   Pubmed ID: 16268663
• Reversal of Experimental Colitis Disease Activity in Mice Following Administration of an Adenoviral IL-10 Vector
  Journal of Inflammation (London, England). Oct, 2005  |   Pubmed ID: 16259632
• DSS-induced Colitis is Exacerbated in STAT-6 Knockout Mice
  Inflammatory Bowel Diseases. Oct, 2005  |   Pubmed ID: 16189417
• Troglitazone, a PPAR-gamma Activator Prevents Endothelial Cell Adhesion Molecule Expression and Lymphocyte Adhesion Mediated by TNF-alpha
  BMC Physiology. Feb, 2005  |   Pubmed ID: 15694007
• Near-infrared Spectroscopy: a Tool to Monitor Cerebral Hemodynamic and Metabolic Changes After Cardiac Arrest in Rats
  Resuscitation. Nov, 2004  |   Pubmed ID: 15531074
• Mmp 9 欠乏コラゲナーゼ誘起脳内出血および脳損傷変異マウスで強化されます。
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Oct, 2004  |   Pubmed ID: 15529013
• Cerebral Cortical Aquaporin-4 Expression in Brain Edema Following Cardiac Arrest in Rats
  Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Oct, 2004  |   Pubmed ID: 15466140
• HIV-associated Dementia, Alzheimer's Disease, Multiple Sclerosis, and Schizophrenia: Gene Expression Review
  Journal of the Neurological Sciences. Sep, 2004  |   Pubmed ID: 15450765
• Pathogenesis of Brain and Spinal Cord Atrophy in Multiple Sclerosis
  Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. Jul, 2004  |   Pubmed ID: 15228754
• Effect of Ifenprodil, a Polyamine Site NMDA Receptor Antagonist, on Brain Edema Formation Following Asphyxial Cardiac Arrest in Rats
  Resuscitation. May, 2004  |   Pubmed ID: 15135198
• ヒトサイトメガロ ウイルス単球の分化と移行戦略としての普及と永続性を誘導します。
  Journal of Virology. May, 2004  |   Pubmed ID: 15078925
• CYP450 Dietary Inhibitors Attenuate TNF-alpha-stimulated Endothelial Molecule Expression and Leukocyte Adhesion
  American Journal of Physiology. Cell Physiology. Apr, 2004  |   Pubmed ID: 15001427
• Stereotactic Radiosurgery Using the Leksell Gamma Knife: Current Trends and Future Directives
  Frontiers in Bioscience : a Journal and Virtual Library. Jan, 2004  |   Pubmed ID: 14766419
• Role of Prostaglandins in Maintaining Gastric Mucus-cell Permeability Against Acid Exposure
  The Journal of Laboratory and Clinical Medicine. Jan, 2004  |   Pubmed ID: 14749685
• Increased Disease Activity in ENOS-deficient Mice in Experimental Colitis
  Free Radical Biology & Medicine. Dec, 2003  |   Pubmed ID: 14680690
• Blood-brain Barrier Disruption in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2003  |   Pubmed ID: 14664465
• Tight Junction Peptide Antagonists Enhance Neutrophil Trans-endothelial Chemotaxis
  Life Sciences. Aug, 2003  |   Pubmed ID: 12875904
• Gamma Knife Irradiation Increases Cerebral Endothelial Expression of Intercellular Adhesion Molecule 1 and E-selectin
  Neurosurgery. Jul, 2003  |   Pubmed ID: 12823884
• Serum from Patients with Multiple Sclerosis Downregulates Occludin and VE-cadherin Expression in Cultured Endothelial Cells
  Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2003  |   Pubmed ID: 12814168
• Randomized, Placebo-controlled, Double Blind, Crossover Design Trial of the Efficacy and Safety of Zestra for Women in Women with and Without Female Sexual Arousal Disorder
  Journal of Sex & Marital Therapy. 2003  |   Pubmed ID: 12735087
• The 3-hydroxy-3-methylglutaryl-CoA Reductase Inhibitor Pravastatin Reduces Disease Activity and Inflammation in Dextran-sulfate Induced Colitis
  The Journal of Pharmacology and Experimental Therapeutics. Apr, 2003  |   Pubmed ID: 12649355
• Transfection of IL-10 Expression Vectors into Endothelial Cultures Attenuates Alpha4beta7-dependent Lymphocyte Adhesion Mediated by MAdCAM-1
  BMC Gastroenterology. Feb, 2003  |   Pubmed ID: 12625840
• Is the Gastric Epithelial Barrier Regulated by Cadherin Recruitment?
  European Journal of Gastroenterology & Hepatology. Dec, 2002  |   Pubmed ID: 12468947
• Devic Disease: Clinical Course, Pathophysiology, and Management
  Pathophysiology : the Official Journal of the International Society for Pathophysiology. Oct, 2002  |   Pubmed ID: 12385963
• Identification of an Occludin Cell Adhesion Recognition Sequence
  Inflammation. Aug, 2002  |   Pubmed ID: 12184633
• Extravascular Transport of Fluorescently Labeled Albumins in the Rat Mesentery
  Microcirculation (New York, N.Y. : 1994). Jul, 2002  |   Pubmed ID: 12080415
• Endothelial Junctional Protein Redistribution and Increased Monolayer Permeability in Human Umbilical Vein Endothelial Cells Isolated During Preeclampsia
  American Journal of Obstetrics and Gynecology. Feb, 2002  |   Pubmed ID: 11854638
• Mild Hypothermia Induced Before Cardiac Arrest Reduces Brain Edema Formation in Rats
  Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. Feb, 2002  |   Pubmed ID: 11825833