Jacques Lapointe

Publications

• Interference Between Surgical Magnetic Drapes and Pacemakers: an Observational Study Comparing Commercially Available Devices and a New Magnetically Isolated Drape
  Biomedical Engineering Online. 2016  |   Pubmed ID: 27430339
• Cyclic Peptides Identified by Phage Display Are Competitive Inhibitors of the TRNA-dependent Amidotransferase of Helicobacter Pylori
  Peptides. May, 2016  |   Pubmed ID: 26976271
• Correction: TRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-Sulfamoyl-Adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications
  PloS One. 2015  |   Pubmed ID: 26039673
• TRNAGlu Increases the Affinity of Glutamyl-tRNA Synthetase for Its Inhibitor Glutamyl-sulfamoyl-adenosine, an Analogue of the Aminoacylation Reaction Intermediate Glutamyl-AMP: Mechanistic and Evolutionary Implications
  PloS One. 2015  |   Pubmed ID: 25860020
• Magnetic Interference of Cardiac Pacemakers from a Surgical Magnetic Drape
  Anesthesia and Analgesia. Mar, 2013  |   Pubmed ID: 23400981
• The 16p13.3 (PDPK1) Genomic Gain in Prostate Cancer: A Potential Role in Disease Progression
  Translational Oncology. Dec, 2012  |   Pubmed ID: 23401739
• PTEN Genomic Deletion Predicts Prostate Cancer Recurrence and is Associated with Low AR Expression and Transcriptional Activity
  BMC Cancer. 2012  |   Pubmed ID: 23171135
• Natural Insertion of the Bro-1 β-lactamase Gene into the GatCAB Operon Affects Moraxella Catarrhalis Aspartyl-tRNA(Asn) Amidotransferase Activity
  Microbiology (Reading, England). Sep, 2012  |   Pubmed ID: 22745266
• The Asparagine-transamidosome from Helicobacter Pylori: a Dual-kinetic Mode in Non-discriminating Aspartyl-tRNA Synthetase Safeguards the Genetic Code
  Nucleic Acids Research. Jun, 2012  |   Pubmed ID: 22362756
• Gln-tRNAGln Synthesis in a Dynamic Transamidosome from Helicobacter Pylori, Where GluRS2 Hydrolyzes Excess Glu-tRNAGln
  Nucleic Acids Research. Nov, 2011  |   Pubmed ID: 21813455
• A Tri-marker Proliferation Index Predicts Biochemical Recurrence After Surgery for Prostate Cancer
  PloS One. 2011  |   Pubmed ID: 21629784
• Inhibition of Helicobacter Pylori Aminoacyl-tRNA Amidotransferase by Chloramphenicol Analogs
  Bioorganic & Medicinal Chemistry. Nov, 2010  |   Pubmed ID: 20943400
• A C-truncated Glutamyl-tRNA Synthetase Specific for TRNA(Glu) is Stimulated by Its Free Complementary Distal Domain: Mechanistic and Evolutionary Implications
  Biochemistry. Jun, 2009  |   Pubmed ID: 19496540
• Peculiar Inhibition of Human Mitochondrial Aspartyl-tRNA Synthetase by Adenylate Analogs
  Biochimie. May, 2009  |   Pubmed ID: 19254750
• Identification of Candidate Prostate Cancer Genes Through Comparative Expression-profiling of Seminal Vesicle
  The Prostate. Aug, 2008  |   Pubmed ID: 18500686
• Inhibition of Helicobacter Pylori Aminoacyl-tRNA Amidotransferase by Puromycin Analogues
  Journal of the American Chemical Society. Mar, 2008  |   Pubmed ID: 18293984
• HCAP-D3 Expression Marks a Prostate Cancer Subtype with Favorable Clinical Behavior and Androgen Signaling Signature
  The American Journal of Surgical Pathology. Feb, 2008  |   Pubmed ID: 18223322
• Mechanism of a GatCAB Amidotransferase: Aspartyl-tRNA Synthetase Increases Its Affinity for Asp-tRNA(Asn) and Novel Aminoacyl-tRNA Analogues Are Competitive Inhibitors
  Biochemistry. Nov, 2007  |   Pubmed ID: 17929881
• Genomic Profiling Reveals Alternative Genetic Pathways of Prostate Tumorigenesis
  Cancer Research. Sep, 2007  |   Pubmed ID: 17875689
• E. Coli Glutamyl-tRNA Synthetase is Inhibited by Anticodon Stem-loop Domains and a Minihelix
  RNA Biology. Jul, 2007  |   Pubmed ID: 17671438
• Inhibition by L-aspartol Adenylate of a Nondiscriminating Aspartyl-tRNA Synthetase Reveals Differences Between the Interactions of Its Active Site with TRNA(Asp) and TRNA(Asn)
  Journal of Enzyme Inhibition and Medicinal Chemistry. Feb, 2007  |   Pubmed ID: 17373551
• A Variant TMPRSS2 Isoform and ERG Fusion Product in Prostate Cancer with Implications for Molecular Diagnosis
  Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Apr, 2007  |   Pubmed ID: 17334351
• Synthesis of Beta-ketophosphonate Analogs of Glutamyl and Glutaminyl Adenylate, and Selective Inhibition of the Corresponding Bacterial Aminoacyl-tRNA Synthetases
  Bioorganic & Medicinal Chemistry. Jan, 2007  |   Pubmed ID: 17049867
• Structural Bases of Transfer RNA-dependent Amino Acid Recognition and Activation by Glutamyl-tRNA Synthetase
  Structure (London, England : 1993). Dec, 2006  |   Pubmed ID: 17161369
• Application of Genomic Technologies to Human Prostate Cancer
  Omics : a Journal of Integrative Biology. 2006  |   Pubmed ID: 17069507
• Two Residues in the Anticodon Recognition Domain of the Aspartyl-tRNA Synthetase from Pseudomonas Aeruginosa Are Individually Implicated in the Recognition of TRNAAsn
  Journal of Bacteriology. Jan, 2006  |   Pubmed ID: 16352843
• The Retinoic Acid Synthesis Gene ALDH1a2 is a Candidate Tumor Suppressor in Prostate Cancer
  Cancer Research. Sep, 2005  |   Pubmed ID: 16166285
• Glu-Q-tRNA(Asp) Synthetase Coded by the YadB Gene, a New Paralog of Aminoacyl-tRNA Synthetase That Glutamylates TRNA(Asp) Anticodon
  Biochimie. Sep-Oct, 2005  |   Pubmed ID: 16164993
• Glutamylsulfamoyladenosine and Pyroglutamylsulfamoyladenosine Are Competitive Inhibitors of E. Coli Glutamyl-tRNA Synthetase
  Journal of Enzyme Inhibition and Medicinal Chemistry. Feb, 2005  |   Pubmed ID: 15895686
• Synthesis and Aminoacyl-tRNA Synthetase Inhibitory Activity of Aspartyl Adenylate Analogs
  Bioorganic & Medicinal Chemistry. Jan, 2005  |   Pubmed ID: 15582453
• Genome-wide Characterization of Gene Expression Variations and DNA Copy Number Changes in Prostate Cancer Cell Lines
  The Prostate. May, 2005  |   Pubmed ID: 15486987
• Crystal Structure of Chloramphenicol Acetyltransferase B2 Encoded by the Multiresistance Transposon Tn2424
  Proteins. Dec, 2004  |   Pubmed ID: 15390264
• A Minimalist Glutamyl-tRNA Synthetase Dedicated to Aminoacylation of the TRNAAsp QUC Anticodon
  Nucleic Acids Research. 2004  |   Pubmed ID: 15150343
• An Aminoacyl-tRNA Synthetase-like Protein Encoded by the Escherichia Coli YadB Gene Glutamylates Specifically TRNAAsp
  Proceedings of the National Academy of Sciences of the United States of America. May, 2004  |   Pubmed ID: 15096594
• The Escherichia Coli YadB Gene Product Reveals a Novel Aminoacyl-tRNA Synthetase Like Activity
  Journal of Molecular Biology. Mar, 2004  |   Pubmed ID: 15003446
• The Zinc-binding Site of a Class I Aminoacyl-tRNA Synthetase is a SWIM Domain That Modulates Amino Acid Binding Via the TRNA Acceptor Arm
  European Journal of Biochemistry / FEBS. Feb, 2004  |   Pubmed ID: 14764088
• Direct Glutaminyl-tRNA Biosynthesis and Indirect Asparaginyl-tRNA Biosynthesis in Pseudomonas Aeruginosa PAO1
  Journal of Bacteriology. Feb, 2004  |   Pubmed ID: 14729703
• Gene Expression Profiling Identifies Clinically Relevant Subtypes of Prostate Cancer
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004  |   Pubmed ID: 14711987
• ATP Binding by Glutamyl-tRNA Synthetase is Switched to the Productive Mode by TRNA Binding
  The EMBO Journal. Feb, 2003  |   Pubmed ID: 12554668