James A. Thomson Regenerative Biology Morgridge Institute for Research Biography Publications Institution JoVE Articles James A. Thomson has not added a biography. If you are James A. Thomson and would like to personalize this page please email our Author Liaison for assistance. Publications Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2012 | Pubmed ID: 22213079 Thermal Stability of FGF Protein is a Determinant Factor in Regulating Self-Renewal, Differentiation and Reprogramming in Human Pluripotent Stem Cells Stem Cells (Dayton, Ohio). Dec, 2011 | Pubmed ID: 22213113 Proteomics and Pluripotency Critical Reviews in Biochemistry and Molecular Biology. Dec, 2011 | Pubmed ID: 21999516 Proteomic and Phosphoproteomic Comparison of Human ES and IPS Cells Nature Methods. 2011 | Pubmed ID: 21983960 High Purity Human-induced Pluripotent Stem Cell-derived Cardiomyocytes: Electrophysiological Properties of Action Potentials and Ionic Currents American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2011 | Pubmed ID: 21890694 Dynamic Chromatin States in Human ES Cells Reveal Potential Regulatory Sequences and Genes Involved in Pluripotency Cell Research. Oct, 2011 | Pubmed ID: 21876557 Human Lymphoblastoid B-cell Lines Reprogrammed to EBV-free Induced Pluripotent Stem Cells Blood. Aug, 2011 | Pubmed ID: 21708888 Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment Stem Cells (Dayton, Ohio). Aug, 2011 | Pubmed ID: 21678528 TF-Cluster: a Pipeline for Identifying Functionally Coordinated Transcription Factors Via Network Decomposition of the Shared Coexpression Connectivity Matrix (SCCM) BMC Systems Biology. 2011 | Pubmed ID: 21496241 Chemically Defined Conditions for Human IPSC Derivation and Culture Nature Methods. May, 2011 | Pubmed ID: 21478862 Genetic Correction and Analysis of Induced Pluripotent Stem Cells from a Patient with Gyrate Atrophy Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21464322 Generation of Red Blood Cells from Human Induced Pluripotent Stem Cells Stem Cells and Development. Sep, 2011 | Pubmed ID: 21434814 Somatic Coding Mutations in Human Induced Pluripotent Stem Cells Nature. Mar, 2011 | Pubmed ID: 21368825 FGF2 Sustains NANOG and Switches the Outcome of BMP4-induced Human Embryonic Stem Cell Differentiation Cell Stem Cell. Mar, 2011 | Pubmed ID: 21362572 Efficient Generation of Transgene-free Induced Pluripotent Stem Cells from Normal and Neoplastic Bone Marrow and Cord Blood Mononuclear Cells Blood. Apr, 2011 | Pubmed ID: 21296996 Hotspots of Aberrant Epigenomic Reprogramming in Human Induced Pluripotent Stem Cells Nature. Mar, 2011 | Pubmed ID: 21289626 A Mesoderm-derived Precursor for Mesenchymal Stem and Endothelial Cells Cell Stem Cell. Dec, 2010 | Pubmed ID: 21112566 The NIH Roadmap Epigenomics Mapping Consortium Nature Biotechnology. Oct, 2010 | Pubmed ID: 20944595 The Social Cognitive Determinants of Offending Drivers' Speeding Behaviour Accident; Analysis and Prevention. Nov, 2010 | Pubmed ID: 20728608 Quantitative Selection of DNA Aptamers Through Microfluidic Selection and High-throughput Sequencing Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20705898 Actin-myosin Contractility is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells Cell Stem Cell. Aug, 2010 | Pubmed ID: 20682449 Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells Cell Stem Cell. May, 2010 | Pubmed ID: 20452322 No Evidence for Clonal Selection Due to Lentiviral Integration Sites in Human Induced Pluripotent Stem Cells Stem Cells (Dayton, Ohio). Apr, 2010 | Pubmed ID: 20166152 Neural Differentiation of Human Induced Pluripotent Stem Cells Follows Developmental Principles but with Variable Potency Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20160098 RNA-Seq Gene Expression Estimation with Read Mapping Uncertainty Bioinformatics (Oxford, England). Feb, 2010 | Pubmed ID: 20022975 The Microwell Control of Embryoid Body Size in Order to Regulate Cardiac Differentiation of Human Embryonic Stem Cells Biomaterials. Mar, 2010 | Pubmed ID: 19945747 Human DNA Methylomes at Base Resolution Show Widespread Epigenomic Differences Nature. Nov, 2009 | Pubmed ID: 19829295 MicroRNA 92b Controls the G1/S Checkpoint Gene P57 in Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jul, 2009 | Pubmed ID: 19544458 MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells Cell. May, 2009 | Pubmed ID: 19409607 ProbeMatch: Rapid Alignment of Oligonucleotides to Genome Allowing Both Gaps and Mismatches Bioinformatics (Oxford, England). Jun, 2009 | Pubmed ID: 19351619 Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences Science (New York, N.Y.). May, 2009 | Pubmed ID: 19325077 Histone Modifications at Human Enhancers Reflect Global Cell-type-specific Gene Expression Nature. May, 2009 | Pubmed ID: 19295514 Functional Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells Circulation Research. Feb, 2009 | Pubmed ID: 19213953 Human Embryonic Stem Cell Phosphoproteome Revealed by Electron Transfer Dissociation Tandem Mass Spectrometry Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19144917 Induced Pluripotent Stem Cells from a Spinal Muscular Atrophy Patient Nature. Jan, 2009 | Pubmed ID: 19098894 Secreted Proteoglycans Directly Mediate Human Embryonic Stem Cell-basic Fibroblast Growth Factor 2 Interactions Critical for Proliferation Stem Cells (Dayton, Ohio). Dec, 2008 | Pubmed ID: 18802039 Cell Type-specific DNA Methylation Patterns in the Human Breast Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18780791 NANOG is a Direct Target of TGFbeta/activin-mediated SMAD Signaling in Human ESCs Cell Stem Cell. Aug, 2008 | Pubmed ID: 18682241 Pluripotent Stem Cell Lines Genes & Development. Aug, 2008 | Pubmed ID: 18676805 Optical Mapping Discerns Genome Wide DNA Methylation Profiles BMC Molecular Biology. 2008 | Pubmed ID: 18667073 Ronin is Essential for Embryogenesis and the Pluripotency of Mouse Embryonic Stem Cells Cell. Jun, 2008 | Pubmed ID: 18585351 Caspase Activity Mediates the Differentiation of Embryonic Stem Cells Cell Stem Cell. Jun, 2008 | Pubmed ID: 18522852 A Study of the Relationships Between Oligonucleotide Properties and Hybridization Signal Intensities from NimbleGen Microarray Datasets Nucleic Acids Research. May, 2008 | Pubmed ID: 18385155 Mass Spectrometry Identifies and Quantifies 74 Unique Histone H4 Isoforms in Differentiating Human Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18326628 Dielectrophoretic Separation of Platelets from Diluted Whole Blood in Microfluidic Channels Electrophoresis. Mar, 2008 | Pubmed ID: 18288670 Steady-state and Pre-steady-state Kinetic Evaluation of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CLpro Cysteine Protease: Development of an Ion-pair Model for Catalysis Biochemistry. Feb, 2008 | Pubmed ID: 18237196 Defined, Feeder-independent Medium for Human Embryonic Stem Cell Culture Current Protocols in Stem Cell Biology. Sep, 2007 | Pubmed ID: 18785163 Whole-genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells Cell Stem Cell. Sep, 2007 | Pubmed ID: 18371364 Conserved Regulation of MAP Kinase Expression by PUF RNA-binding Proteins PLoS Genetics. Dec, 2007 | Pubmed ID: 18166083 Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells Science (New York, N.Y.). Dec, 2007 | Pubmed ID: 18029452 A Microarray Analysis of the Emergence of Embryonic Definitive Hematopoiesis Experimental Hematology. Sep, 2007 | Pubmed ID: 17761287 LongSAGE Profiling of Nine Human Embryonic Stem Cell Lines Genome Biology. 2007 | Pubmed ID: 17570852 Defined Substrates for Human Embryonic Stem Cell Growth Identified from Surface Arrays ACS Chemical Biology. May, 2007 | Pubmed ID: 17480050 Differential Requirements for Hematopoietic Commitment Between Human and Rhesus Embryonic Stem Cells Stem Cells (Dayton, Ohio). Feb, 2007 | Pubmed ID: 17284653 Nanog and Transcriptional Networks in Embryonic Stem Cell Pluripotency Cell Research. Jan, 2007 | Pubmed ID: 17211451 Microarray Analysis of Stem Cells and Differentiation Methods in Enzymology. 2006 | Pubmed ID: 17161699 A Severe De Novo Methylation of Episomal Vectors by Human ES Cells Biochemical and Biophysical Research Communications. Nov, 2006 | Pubmed ID: 16973130 Feeder-independent Culture of Human Embryonic Stem Cells Nature Methods. Aug, 2006 | Pubmed ID: 16862139 Leukosialin (CD43) Defines Hematopoietic Progenitors in Human Embryonic Stem Cell Differentiation Cultures Blood. Sep, 2006 | Pubmed ID: 16757688 Directed Differentiation of Human Embryonic Stem Cells into Functional Dendritic Cells Through the Myeloid Pathway Journal of Immunology (Baltimore, Md. : 1950). Mar, 2006 | Pubmed ID: 16493050 Derivation of Human Embryonic Stem Cells in Defined Conditions Nature Biotechnology. Feb, 2006 | Pubmed ID: 16388305 Basic Fibroblast Growth Factor Support of Human Embryonic Stem Cell Self-renewal Stem Cells (Dayton, Ohio). Mar, 2006 | Pubmed ID: 16282444 Human Embryonic Stem Cell-derived Hematopoietic Cells Are Capable of Engrafting Primary As Well As Secondary Fetal Sheep Recipients Blood. Mar, 2006 | Pubmed ID: 16278307 Human Embryonic Stem Cells Reprogram Myeloid Precursors Following Cell-cell Fusion Stem Cells (Dayton, Ohio). Jan, 2006 | Pubmed ID: 16210403 Influence of Virtual Reality Training on the Roadside Crossing Judgments of Child Pedestrians Journal of Experimental Psychology. Applied. Sep, 2005 | Pubmed ID: 16221036 Human ERas Gene Has an Upstream Premature Polyadenylation Signal That Results in a Truncated, Noncoding Transcript Stem Cells (Dayton, Ohio). Nov-Dec, 2005 | Pubmed ID: 16081664 The Effects of Adult Guidance and Peer Discussion on the Development of Children's Representations: Evidence from the Training of Pedestrian Skills British Journal of Psychology (London, England : 1953). May, 2005 | Pubmed ID: 15969830 Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jun-Jul, 2005 | Pubmed ID: 15917474 Basic FGF and Suppression of BMP Signaling Sustain Undifferentiated Proliferation of Human ES Cells Nature Methods. Mar, 2005 | Pubmed ID: 15782187 Differentiation of Human Embryonic Stem Cells Occurs Through Symmetric Cell Division Stem Cells (Dayton, Ohio). Feb, 2005 | Pubmed ID: 15671139 A Germ Cell Origin of Embryonic Stem Cells? Development (Cambridge, England). Jan, 2005 | Pubmed ID: 15623802 Human Embryonic Stem Cell-derived CD34+ Cells: Efficient Production in the Coculture with OP9 Stromal Cells and Analysis of Lymphohematopoietic Potential Blood. Jan, 2005 | Pubmed ID: 15374881 Crystal Structure of Human ABAD/HSD10 with a Bound Inhibitor: Implications for Design of Alzheimer's Disease Therapeutics Journal of Molecular Biology. Sep, 2004 | Pubmed ID: 15342248 Arrays for the Combinatorial Exploration of Cell Adhesion Journal of the American Chemical Society. Sep, 2004 | Pubmed ID: 15339142 Trophoblast Differentiation in Embryoid Bodies Derived from Human Embryonic Stem Cells Endocrinology. Apr, 2004 | Pubmed ID: 14684604 Recurrent Gain of Chromosomes 17q and 12 in Cultured Human Embryonic Stem Cells Nature Biotechnology. Jan, 2004 | Pubmed ID: 14661028 Functional Endothelial Cells Derived from Rhesus Monkey Embryonic Stem Cells Blood. Feb, 2004 | Pubmed ID: 14563647 Gene Expression Patterns in Human Embryonic Stem Cells and Human Pluripotent Germ Cell Tumors Proceedings of the National Academy of Sciences of the United States of America. Nov, 2003 | Pubmed ID: 14595015 Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme Journal of Virology. Jul, 2003 | Pubmed ID: 12805457 Human Embryonic Stem Cells Develop into Multiple Types of Cardiac Myocytes: Action Potential Characterization Circulation Research. Jul, 2003 | Pubmed ID: 12791707 Homologous Recombination in Human Embryonic Stem Cells Nature Biotechnology. Mar, 2003 | Pubmed ID: 12577066 High-level Sustained Transgene Expression in Human Embryonic Stem Cells Using Lentiviral Vectors Stem Cells (Dayton, Ohio). 2003 | Pubmed ID: 12529558 BMP4 Initiates Human Embryonic Stem Cell Differentiation to Trophoblast Nature Biotechnology. Dec, 2002 | Pubmed ID: 12426580 Surface Antigens of Human Embryonic Stem Cells: Changes Upon Differentiation in Culture Journal of Anatomy. Mar, 2002 | Pubmed ID: 12033729 Efficient Method for Expressing Transgenes in Nonhuman Primate Embryos Using a Stable Episomal Vector Molecular Reproduction and Development. May, 2002 | Pubmed ID: 11933162 On-Line Updating of Spatial Information Druing Locomotion Without Vision Journal of Motor Behavior. Mar, 1999 | Pubmed ID: 11177618 Одноместный Читайте и парные Конец мРНК-Seq Illumina библиотек из 10 нанограмм Всего РНК Srikumar Sengupta1, Jennifer M. Bolin1, Victor Ruotti1, Bao Kim Nguyen1, James A. Thomson1,2,3, Angela L. Elwell1, Ron Stewart1 1Regenerative Biology, Morgridge Institute for Research, 2Department of Cell & Regenerative Biology, University of Wisconsin, 3Department of Molecular, Cellular, & Regenerative Biology, University of California JoVE 3340 Biology
Одноместный Читайте и парные Конец мРНК-Seq Illumina библиотек из 10 нанограмм Всего РНК Srikumar Sengupta1, Jennifer M. Bolin1, Victor Ruotti1, Bao Kim Nguyen1, James A. Thomson1,2,3, Angela L. Elwell1, Ron Stewart1 1Regenerative Biology, Morgridge Institute for Research, 2Department of Cell & Regenerative Biology, University of Wisconsin, 3Department of Molecular, Cellular, & Regenerative Biology, University of California JoVE 3340 Biology