James Koropatnick Microbiology and Immunology Western University Biography Publications Institution JoVE Articles James Koropatnick has not added a biography. If you are James Koropatnick and would like to personalize this page please email our Author Liaison for assistance. Publications Single-walled Carbon Nanotubes Noncovalently Functionalized with Lipid Modified Polyethylenimine for SiRNA Delivery in Vitro and in Vivo Bioconjugate Chemistry. Oct, 2014 | Pubmed ID: 25216445 BRCA2 Inhibition Enhances Cisplatin-mediated Alterations in Tumor Cell Proliferation, Metabolism, and Metastasis Molecular Oncology. Dec, 2014 | Pubmed ID: 24974076 Intravenous Ascorbic Acid As an Adjuvant to Interleukin-2 Immunotherapy Journal of Translational Medicine. 2014 | Pubmed ID: 24884532 Indoleamine 2,3-dioxygenase Mediates Immune-independent Human Tumor Cell Resistance to Olaparib, Gamma Radiation, and Cisplatin Oncotarget. May, 2014 | Pubmed ID: 24784564 Targeted SiRNA Silencing of Indoleamine 2, 3-dioxygenase in Antigen-presenting Cells Using Mannose-conjugated Liposomes: a Novel Strategy for Treatment of Melanoma Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb-Mar, 2014 | Pubmed ID: 24509175 Non-covalently Functionalized Single-walled Carbon Nanotube for Topical SiRNA Delivery into Melanoma Biomaterials. Mar, 2014 | Pubmed ID: 24424208 Vaccinia Virus Outperforms a Panel of Other Poxviruses As a Potent Oncolytic Agent for the Control of Head and Neck Squamous Cell Carcinoma Cell Lines Intervirology. 2014 | Pubmed ID: 23942307 Imaging Tumor Growth Non-invasively Using Expression of MagA or Modified Ferritin Subunits to Augment Intracellular Contrast for Repetitive MRI Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Feb, 2014 | Pubmed ID: 23836502 Metallothionein-I- and -II-deficient Mice Display Increased Susceptibility to Cadmium-induced Fetal Growth Restriction American Journal of Physiology. Endocrinology and Metabolism. Sep, 2013 | Pubmed ID: 23880315 High Frequency of Activating PIK3CA Mutations in Human Papillomavirus-positive Oropharyngeal Cancer JAMA Otolaryngology-- Head & Neck Surgery. Jun, 2013 | Pubmed ID: 23787421 Does HPV Type Affect Outcome in Oropharyngeal Cancer? Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale. 2013 | Pubmed ID: 23663293 A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases Case Reports in Oncological Medicine. 2013 | Pubmed ID: 23653877 Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells Via the Induction of Combined "Complementary Lethality" Molecular Therapy. Nucleic Acids. 2013 | Pubmed ID: 23481354 Silenciamiento IDO En Células Dendríticas: Un Nuevo Enfoque Para Mejorar La Inmunoterapia Del Cáncer En Un Modelo De Cáncer Mamario Murino International Journal of Cancer. Journal International Du Cancer. Feb, 2013 | Pubmed ID: 22870862 A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing ISRN Oncology. 2012 | Pubmed ID: 23304554 Frequent Mutations in TP53 and CDKN2A Found by Next-generation Sequencing of Head and Neck Cancer Cell Lines Archives of Otolaryngology--head & Neck Surgery. Aug, 2012 | Pubmed ID: 22911296 Ki-67 Expression Predicts Radiotherapy Failure in Early Glottic Cancer Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale. Apr, 2012 | Pubmed ID: 22569013 Reduction of Tumorigenicity by Placental Extracts Anticancer Research. Apr, 2012 | Pubmed ID: 22493344 Detection of Circulating Tumor Cells in Advanced Head and Neck Cancer Using the CellSearch System Head & Neck. Oct, 2012 | Pubmed ID: 22076949 Imaging of Homeostatic, Neoplastic, and Injured Tissues by HA-based Probes Biomacromolecules. Jan, 2012 | Pubmed ID: 22066590 Intravenous Ascorbic Acid to Prevent and Treat Cancer-associated Sepsis? Journal of Translational Medicine. 2011 | Pubmed ID: 21375761 Expression of Functional Metallothionein Isoforms in Papillary Thyroid Cancer Molecular and Cellular Endocrinology. Apr, 2009 | Pubmed ID: 19356627 Enhancement of Cytotoxicity of Natural Product Drugs Against Multidrug Resistant Variant Cell Lines of Human Head and Neck Squamous Cell Carcinoma and Breast Carcinoma by Tesmilifene Cancer Letters. Feb, 2009 | Pubmed ID: 18986763 Exosomes As a Tumor Immune Escape Mechanism: Possible Therapeutic Implications Journal of Translational Medicine. 2008 | Pubmed ID: 18644158 ODN 491, a Novel Antisense Oligodeoxynucleotide That Targets Thymidylate Synthase, Exerts Cell-specific Effects in Human Tumor Cell Lines DNA and Cell Biology. May, 2008 | Pubmed ID: 18358073 Antisense Targeting of Thymidylate Synthase (TS) MRNA Increases TS Gene Transcription and TS Protein: Effects on Human Tumor Cell Sensitivity to TS Enzyme-inhibiting Drugs Gene Expression. 2007 | Pubmed ID: 17605297 Induction of Functional MT1 and MT2 Isoforms by Calcium in Anaplastic Thyroid Carcinoma Cells FEBS Letters. May, 2007 | Pubmed ID: 17485079 Mouse Monocytes (RAW CELLS) and the Handling of Cysteine and Homocysteine S-conjugates of Inorganic Mercury and Methylmercury Journal of Toxicology and Environmental Health. Part A. May, 2007 | Pubmed ID: 17454556 Combination Silencer RNA (siRNA) Targeting Bcl-2 Antagonizes SiRNA Against Thymidylate Synthase in Human Tumor Cell Lines The Journal of Pharmacology and Experimental Therapeutics. Jul, 2007 | Pubmed ID: 17452420 The Hyaluronan Receptors CD44 and Rhamm (CD168) Form Complexes with ERK1,2 That Sustain High Basal Motility in Breast Cancer Cells The Journal of Biological Chemistry. Jun, 2007 | Pubmed ID: 17392272 Tangeretin and Nobiletin Induce G1 Cell Cycle Arrest but Not Apoptosis in Human Breast and Colon Cancer Cells Cancer Letters. Jun, 2007 | Pubmed ID: 17197076 In Vivo Inhibition of Growth of Human Tumor Lines by Flavonoid Fractions from Cranberry Extract Nutrition and Cancer. 2006 | Pubmed ID: 17176222 Reinstalling Antitumor Immunity by Inhibiting Tumor-derived Immunosuppressive Molecule IDO Through RNA Interference Journal of Immunology (Baltimore, Md. : 1950). Oct, 2006 | Pubmed ID: 17015752 Therapeutic Potential of Antisense Oligodeoxynucleotides to Down-regulate Thymidylate Synthase in Mesothelioma Molecular Cancer Therapeutics. Jun, 2006 | Pubmed ID: 16818500 Toxicology of Antisense Therapeutics Toxicology and Applied Pharmacology. Nov, 2004 | Pubmed ID: 15519609 A Flavonoid Fraction from Cranberry Extract Inhibits Proliferation of Human Tumor Cell Lines The Journal of Nutrition. Jun, 2004 | Pubmed ID: 15173424 Use of the Humanized Anti-epidermal Growth Factor Receptor Monoclonal Antibody H-R3 in Combination with Radiotherapy in the Treatment of Locally Advanced Head and Neck Cancer Patients Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. May, 2004 | Pubmed ID: 15117987 Metallothionein Mediates the Level and Activity of Nuclear Factor Kappa B in Murine Fibroblasts The Journal of Pharmacology and Experimental Therapeutics. Aug, 2004 | Pubmed ID: 15039454 Signaling Events for Metallothionein Induction Mutation Research. Dec, 2003 | Pubmed ID: 14643422 A "combination Oligonucleotide" Antisense Strategy to Downregulate Thymidylate Synthase and Decrease Tumor Cell Growth and Drug Resistance Cancer Gene Therapy. Apr, 2003 | Pubmed ID: 12679800 A Sensitive Time-resolved Fluorescent Immunoassay for Metallothionein Protein Journal of Immunological Methods. Jan, 2003 | Pubmed ID: 12505728 The Means to an End of Tumor Cell Resistance to Chemotherapeutic Drugs Targeting Thymidylate Synthase: Shoot the Messenger Current Drug Targets. Aug, 2002 | Pubmed ID: 12102601 Reduction of Copper and Metallothionein in Toxic Milk Mice by Tetrathiomolybdate, but Not Deferiprone Journal of Inorganic Biochemistry. Jan, 2002 | Pubmed ID: 11803042 Evaluación de la efectividad del medicamento para el cáncer Sensibilización Mateusz Rytelewski1, Adrian Buensuceso2, Hon S. Leong3, Bonnie J. Deroo2, Ann F. Chambers4, James Koropatnick1 1Microbiology and Immunology, Western University, 2Biochemistry, Western University, 3Surgery, Western University, 4Oncology, Western University Medicine
Evaluación de la efectividad del medicamento para el cáncer Sensibilización Mateusz Rytelewski1, Adrian Buensuceso2, Hon S. Leong3, Bonnie J. Deroo2, Ann F. Chambers4, James Koropatnick1 1Microbiology and Immunology, Western University, 2Biochemistry, Western University, 3Surgery, Western University, 4Oncology, Western University Medicine