Jason Scragg

Publications

• Inhibition of the Voltage-gated Potassium Channel Kv1.5 by Hydrogen Sulfide Attenuates Remodeling Through S-nitrosylation-mediated Signaling
  Communications Biology. Jun, 2023  |   Pubmed ID: 37336943
• Hydrogen Sulfide Regulates Hippocampal Neuron Excitability Via S-sulfhydration of Kv2.1
  Scientific Reports. Apr, 2021  |   Pubmed ID: 33854181
• Kv1.3 Voltage-gated Potassium Channels Link Cellular Respiration to Proliferation Through a Non-conducting Mechanism
  Cell Death & Disease. Apr, 2021  |   Pubmed ID: 33828089
• Brown and Beige Adipose Tissue Regulate Systemic Metabolism Through a Metabolite Interorgan Signaling Axis
  Nature Communications. Mar, 2021  |   Pubmed ID: 33772024
• Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy
  Journal of the American Heart Association. Sep, 2020  |   Pubmed ID: 32892688
• Piezo1 Channel Activation Mimics High Glucose As a Stimulator of Insulin Release
  Scientific Reports. Nov, 2019  |   Pubmed ID: 31727906
• Multiple Mechanisms Mediating Carbon Monoxide Inhibition of the Voltage-gated K Channel Kv1.5
  Cell Death & Disease. Nov, 2017  |   Pubmed ID: 29095440
• A Key Role for Peroxynitrite-mediated Inhibition of Cardiac ERG (Kv11.1) K Channels in Carbon Monoxide-induced Proarrhythmic Early Afterdepolarizations
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2017  |   Pubmed ID: 28743763
• Heme Oxygenase-1 Derived Carbon Monoxide Suppresses Aβ Toxicity in Astrocytes
  Cell Death & Disease. Jun, 2017  |   Pubmed ID: 28617444
• Redox-Dependent Modulation of T-Type Ca(2+) Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P
  Antioxidants & Redox Signaling. Aug, 2016  |   Pubmed ID: 27306612
• Regulation of the T-type Ca(2+) Channel Cav3.2 by Hydrogen Sulfide: Emerging Controversies Concerning the Role of H2 S in Nociception
  The Journal of Physiology. Aug, 2016  |   Pubmed ID: 26804000
• Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide
  Advances in Experimental Medicine and Biology. 2015  |   Pubmed ID: 26303500
• Heme Oxygenase-1 Influences Apoptosis Via CO-mediated Inhibition of K+ Channels
  Advances in Experimental Medicine and Biology. 2015  |   Pubmed ID: 26303499
• H2S Does Not Regulate Proliferation Via T-type Ca2+ Channels
  Biochemical and Biophysical Research Communications. Jun, 2015  |   Pubmed ID: 25918023
• Oxygen-dependent Hydroxylation by FIH Regulates the TRPV3 Ion Channel
  Journal of Cell Science. Jan, 2015  |   Pubmed ID: 25413349
• Heme Oxygenase-1 Regulates Cell Proliferation Via Carbon Monoxide-mediated Inhibition of T-type Ca2+ Channels
  Pflugers Archiv : European Journal of Physiology. Feb, 2015  |   Pubmed ID: 24744106
• Hydrogen Sulfide Inhibits Cav3.2 T-type Ca2+ Channels
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2014  |   Pubmed ID: 25183670
• Inhibition of the Cardiac Na⁺ Channel Nav1.5 by Carbon Monoxide
  The Journal of Biological Chemistry. Jun, 2014  |   Pubmed ID: 24719320
• Carbon Monoxide Inhibition of Cav3.2 T-type Ca2+ Channels Reveals Tonic Modulation by Thioredoxin
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2013  |   Pubmed ID: 23671274
• Carbon Monoxide Induces Cardiac Arrhythmia Via Induction of the Late Na+ Current
  American Journal of Respiratory and Critical Care Medicine. Oct, 2012  |   Pubmed ID: 22822026
• Carbon Monoxide Mediates the Anti-apoptotic Effects of Heme Oxygenase-1 in Medulloblastoma DAOY Cells Via K+ Channel Inhibition
  The Journal of Biological Chemistry. Jul, 2012  |   Pubmed ID: 22593583
• Cellular Consequences of the Expression of Alzheimer's Disease-causing Presenilin 1 Mutations in Human Neuroblastoma (SH-SY5Y) Cells
  Brain Research. Mar, 2012  |   Pubmed ID: 22297172
• Modulation of Ion Channels by Hydrogen Sulfide
  Antioxidants & Redox Signaling. Jul, 2012  |   Pubmed ID: 22074224
• Carbon Monoxide Protects Against Oxidant-induced Apoptosis Via Inhibition of Kv2.1
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2011  |   Pubmed ID: 21248240
• Hypoxia and Neurodegeneration
  Annals of the New York Academy of Sciences. Oct, 2009  |   Pubmed ID: 19845619
• Ion Channels As Effectors in Carbon Monoxide Signaling
  Communicative & Integrative Biology. May, 2009  |   Pubmed ID: 19641743
• Carbon Monoxide Inhibits L-type Ca2+ Channels Via Redox Modulation of Key Cysteine Residues by Mitochondrial Reactive Oxygen Species
  The Journal of Biological Chemistry. Sep, 2008  |   Pubmed ID: 18596041
• Modulation of HTREK-1 by Carbon Monoxide
  Neuroreport. Feb, 2008  |   Pubmed ID: 18303579
• H2O 2-stimulated Ca2+ Influx Via TRPM2 is Not the Sole Determinant of Subsequent Cell Death
  Pflugers Archiv : European Journal of Physiology. Mar, 2008  |   Pubmed ID: 18043941
• Molecular Requirements for L-type Ca2+ Channel Blockade by Testosterone
  Cell Calcium. Jul, 2007  |   Pubmed ID: 17173968
• A Central Role for ROS in the Functional Remodelling of L-type Ca2+ Channels by Hypoxia
  Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Dec, 2005  |   Pubmed ID: 16321794
• Constitutive Activity of Human Angiotensin II Type-1 Receptors by Gq Overexpression
  Biochemical and Biophysical Research Communications. Aug, 2005  |   Pubmed ID: 15992776
• Constitutive Activity of Endogenous Receptors by Inducible Gq Overexpression
  Biochemical and Biophysical Research Communications. Jun, 2005  |   Pubmed ID: 15883008
• Alzheimer's Amyloid Peptides Mediate Hypoxic Up-regulation of L-type Ca2+ Channels
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2005  |   Pubmed ID: 15494446
• Testosterone is a Potent Inhibitor of L-type Ca(2+) Channels
  Biochemical and Biophysical Research Communications. May, 2004  |   Pubmed ID: 15120629
• Analysis of Oxygen-sensitive Human Cardiac L-type Ca2+ Channel Alpha1C Subunit (hHT Isoform)
  Methods in Enzymology. 2004  |   Pubmed ID: 15063682