Solid Phase Synthesis of a Functionalized Bis-Peptide Using …
Published 5/15/2012
The 2009 Lindau Nobel Laureate Meeting: Erwin Neher, Physiology or Medicine 1991
German biophysicist Erwin Neher shared the 1991 Nobel Prize in Physiology or Medicine with Bert Sakmann for their pioneering work measuring the activity of single ion channels in cells.
The 2009 Lindau Nobel Laureate Meeting: Werner Arber, Physiology or Medicine 1978
Swiss microbial geneticist, Werner Arber shared the 1978 Nobel Prize in Physiology or Medicine with Hamilton Smith and Daniel Nathans for their discovery of restriction endonucleases. Arber found that viral DNA introduced into a non-specific bacterial host was changed, while host DNA was protected by methylation. He theorized that a microbial enzyme cut the DNA into smaller pieces, while at the same time, the methylated host DNA was protected from its own enzymes. Later work done by Nathans and Smith validated his theory, which laid the foundation for recombinant DNA technology.
Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells
Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky
We describe a method for generating regulatory, memory and naïve T cells from a single human blood donor. Polarized Tregs can be then compared to other subsets in a variety of genetic and functional applications with genetic homogeneity, including a suppression assay also detailed here.
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