Jeff Abramson Department of Physiology David Geffen School of Medicine, UCLA Biography Publications Institution JoVE Articles Jeff Abramson has not added a biography. If you are Jeff Abramson and would like to personalize this page please email our Author Liaison for assistance. Publications Structural Biology. It's All in the Symmetry Science (New York, N.Y.). Feb, 2012 | Pubmed ID: 22323810 Characterization and Purification of a Na+/Ca2+ Exchanger from an Archaebacterium The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22287543 Affixing the N-terminal Alpha Helix of the Voltage Dependent Anion Channel to the Channel's Wall Does Not Prevent Its Voltage Gating The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22275367 Bridging the Gap Between Structure and Kinetics of Human SGLT1 American Journal of Physiology. Cell Physiology. Dec, 2011 | Pubmed ID: 22159082 Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator Yields Unique Insight into Sugar Recognition Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21593407 The Mechanism of Sodium and Substrate Release from the Binding Pocket of VSGLT Nature. Dec, 2010 | Pubmed ID: 21131949 Water Permeation Through the Sodium-dependent Galactose Cotransporter VSGLT Biophysical Journal. Oct, 2010 | Pubmed ID: 20923633 Structures of Aminoacylase 3 in Complex with Acetylated Substrates Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20921362 Rapid Readout Detector Captures Protein Time-resolved WAXS Nature Methods. Oct, 2010 | Pubmed ID: 20885435 The 3D Structures of VDAC Represent a Native Conformation Trends in Biochemical Sciences. Sep, 2010 | Pubmed ID: 20708406 Transfer of Ion Binding Site from Ether-a-go-go to Shaker: Mg2+ Binds to Resting State to Modulate Channel Opening The Journal of General Physiology. May, 2010 | Pubmed ID: 20385745 Bridging the Gap: a GFP-based Strategy for Overexpression and Purification of Membrane Proteins with Intra and Extracellular C-termini Protein Science : a Publication of the Protein Society. Apr, 2010 | Pubmed ID: 20196076 Fluorescence Detection of Heavy Atom Labeling (FD-HAL): A Rapid Method for Identifying Covalently Modified Cysteine Residues by Phasing Atoms Journal of Structural Biology. Feb, 2010 | Pubmed ID: 20152903 Gated Access to the Pore of a P2X Receptor: Structural Implications for Closed-open Transitions The Journal of Biological Chemistry. Mar, 2010 | Pubmed ID: 20093367 Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation Molecular & Cellular Proteomics : MCP. May, 2010 | Pubmed ID: 20093275 The Electrostatics of VDAC: Implications for Selectivity and Gating Journal of Molecular Biology. Feb, 2010 | Pubmed ID: 20005234 Keeping an Eye on Membrane Transport by TR-WAXS Structure (London, England : 1993). Sep, 2009 | Pubmed ID: 19748336 Structure and Function of Na(+)-symporters with Inverted Repeats Current Opinion in Structural Biology. Aug, 2009 | Pubmed ID: 19631523 Crystal Packing Analysis of Murine VDAC1 Crystals in a Lipidic Environment Reveals Novel Insights on Oligomerization and Orientation Channels (Austin, Tex.). May-Jun, 2009 | Pubmed ID: 19574737 Structure and Functional Analysis of a Ca2+ Sensor Mutant of the Na+/Ca2+ Exchanger The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19332552 The Crystal Structure of Mouse VDAC1 at 2.3 A Resolution Reveals Mechanistic Insights into Metabolite Gating Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 18988731 The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/sugar Symport Science (New York, N.Y.). Aug, 2008 | Pubmed ID: 18599740 How Does Regulatory Ca2+ Regulate the Na+-Ca2+ Exchanger? Channels (Austin, Tex.). Nov-Dec, 2007 | Pubmed ID: 18690047 The Second Ca2+-binding Domain of the Na+ Ca2+ Exchanger is Essential for Regulation: Crystal Structures and Mutational Analysis Proceedings of the National Academy of Sciences of the United States of America. Nov, 2007 | Pubmed ID: 17962412 What We Know About the Structure of NCX1 and How It Relates to Its Function Annals of the New York Academy of Sciences. Mar, 2007 | Pubmed ID: 17303833 The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger Reveals a Novel Ca2+ Binding Motif The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16774926 Lactose Permease As a Paradigm for Membrane Transport Proteins (Review) Molecular Membrane Biology. Jul-Aug, 2004 | Pubmed ID: 15371012 Structural Comparison of Lactose Permease and the Glycerol-3-phosphate Antiporter: Members of the Major Facilitator Superfamily Current Opinion in Structural Biology. Aug, 2004 | Pubmed ID: 15313234 The Lactose Permease of Escherichia Coli: Overall Structure, the Sugar-binding Site and the Alternating Access Model for Transport FEBS Letters. Nov, 2003 | Pubmed ID: 14630326 Structure and Mechanism of the Lactose Permease of Escherichia Coli Science (New York, N.Y.). Aug, 2003 | Pubmed ID: 12893935 Structure and Function of Quinone Binding Membrane Proteins Advances in Protein Chemistry. 2003 | Pubmed ID: 12629970 The X-ray Crystal Structures of Wild-type and EQ(I-286) Mutant Cytochrome C Oxidases from Rhodobacter Sphaeroides Journal of Molecular Biology. Aug, 2002 | Pubmed ID: 12144789 Purification and Crystallization of the Respiratory Complex Formate Dehydrogenase-N from Escherichia Coli Acta Crystallographica. Section D, Biological Crystallography. Jan, 2002 | Pubmed ID: 11752799 High-throughput Crystallization of Membrane Proteins Using the Lipidic Bicelle Method Rachna Ujwal1, Jeff Abramson2 1UCLA-DOE Institute for Genomics and Proteomics, University of California Los Angeles, 2Department of Physiology, David Geffen School of Medicine, UCLA JoVE 3383 Biology
High-throughput Crystallization of Membrane Proteins Using the Lipidic Bicelle Method Rachna Ujwal1, Jeff Abramson2 1UCLA-DOE Institute for Genomics and Proteomics, University of California Los Angeles, 2Department of Physiology, David Geffen School of Medicine, UCLA JoVE 3383 Biology