Jernej Ule Laboratory of Molecular Biology Medical Research Council - MRC Biography Publications Institution JoVE Articles Jernej Ule has not added a biography. If you are Jernej Ule and would like to personalize this page please email our Author Liaison for assistance. Publications Using Human Pluripotent Stem Cells to Study Post-transcriptional Mechanisms of Neurodegenerative Diseases Brain Research. Jan, 2012 | Pubmed ID: 22285437 Protein-RNA Interactions: New Genomic Technologies and Perspectives Nature Reviews. Genetics. Feb, 2011 | Pubmed ID: 22251872 Selective Inhibition of MicroRNA Accessibility by RBM38 is Required for P53 Activity Nature Communications. 2011 | Pubmed ID: 22027593 The Cyclin K/Cdk12 Complex Maintains Genomic Stability Via Regulation of Expression of DNA Damage Response Genes Genes & Development. Oct, 2011 | Pubmed ID: 22012619 Analysis of Alternative Splicing Associated with Aging and Neurodegeneration in the Human Brain Genome Research. Oct, 2011 | Pubmed ID: 21846794 The RNA-binding Protein Rrm4 is Essential for Efficient Secretion of Endochitinase Cts1 Molecular & Cellular Proteomics : MCP. Dec, 2011 | Pubmed ID: 21808052 Characterizing the RNA Targets and Position-dependent Splicing Regulation by TDP-43 Nature Neuroscience. Apr, 2011 | Pubmed ID: 21358640 Understanding Splicing Regulation Through RNA Splicing Maps Trends in Genetics : TIG. Mar, 2011 | Pubmed ID: 21232811 TDP-43 Regulates Its MRNA Levels Through a Negative Feedback Loop The EMBO Journal. Jan, 2011 | Pubmed ID: 21131904 ICLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions PLoS Biology. 2010 | Pubmed ID: 21048981 ICLIP Reveals the Function of HnRNP Particles in Splicing at Individual Nucleotide Resolution Nature Structural & Molecular Biology. Jul, 2010 | Pubmed ID: 20601959 The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite Frontiers in Neural Circuits. 2010 | Pubmed ID: 20407637 High-throughput Sequencing Methods to Study Neuronal RNA-protein Interactions Biochemical Society Transactions. Dec, 2009 | Pubmed ID: 19909262 CLIP: Construction of CDNA Libraries for High-throughput Sequencing from RNAs Cross-linked to Proteins in Vivo Methods (San Diego, Calif.). Jul, 2009 | Pubmed ID: 19272451 HITS-CLIP Yields Genome-wide Insights into Brain Alternative RNA Processing Nature. Nov, 2008 | Pubmed ID: 18978773 Ribonucleoprotein Complexes in Neurologic Diseases Current Opinion in Neurobiology. Oct, 2008 | Pubmed ID: 18929657 Jernej Ule: an RNA Runaway Success. Interview by Ruth Williams The Journal of Cell Biology. Feb, 2008 | Pubmed ID: 18268098 Functional and Mechanistic Insights from Genome-wide Studies of Splicing Regulation in the Brain Advances in Experimental Medicine and Biology. 2007 | Pubmed ID: 18380345 Evolution of Nova-dependent Splicing Regulation in the Brain PLoS Genetics. Oct, 2007 | Pubmed ID: 17937501 An RNA Map Predicting Nova-dependent Splicing Regulation Nature. Nov, 2006 | Pubmed ID: 17065982 RNA Binding Proteins and the Regulation of Neuronal Synaptic Plasticity Current Opinion in Neurobiology. Feb, 2006 | Pubmed ID: 16418001 CLIP: a Method for Identifying Protein-RNA Interaction Sites in Living Cells Methods (San Diego, Calif.). Dec, 2005 | Pubmed ID: 16314267 Common Molecular Pathways Mediate Long-term Potentiation of Synaptic Excitation and Slow Synaptic Inhibition Cell. Oct, 2005 | Pubmed ID: 16213216 Nova Regulates Brain-specific Splicing to Shape the Synapse Nature Genetics. Aug, 2005 | Pubmed ID: 16041372 CLIP Identifies Nova-regulated RNA Networks in the Brain Science (New York, N.Y.). Nov, 2003 | Pubmed ID: 14615540 iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution Julian Konig1, Kathi Zarnack2, Gregor Rot3, Tomaz Curk3, Melis Kayikci1, Blaz Zupan3, Daniel J. Turner4, Nicholas M. Luscombe2, Jernej Ule1 1Laboratory of Molecular Biology, Medical Research Council - MRC, 2European Bioinformatics Institute, EMBL Heidelberg, 3Computer and Information Science, University of Ljubljana, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute JoVE 2638 Biology
iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution Julian Konig1, Kathi Zarnack2, Gregor Rot3, Tomaz Curk3, Melis Kayikci1, Blaz Zupan3, Daniel J. Turner4, Nicholas M. Luscombe2, Jernej Ule1 1Laboratory of Molecular Biology, Medical Research Council - MRC, 2European Bioinformatics Institute, EMBL Heidelberg, 3Computer and Information Science, University of Ljubljana, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute JoVE 2638 Biology