Jesper B. Birk Section of Molecular Physiology, Department of Nutrition, Exercise and Sports University of Copenhagen Biography Publications Institution JoVE Articles Jesper B. Birk has not added a biography. If you are Jesper B. Birk and would like to personalize this page please email our Author Liaison for assistance. Publications AXIN1 Knockout Does Not Alter AMPK/mTORC1 Regulation and Glucose Metabolism in Mouse Skeletal Muscle The Journal of Physiology. Apr, 2021 | Pubmed ID: 33913171 The Insulin-sensitizing Effect of a Single Exercise Bout is Similar in Type I and Type II Human Muscle Fibres The Journal of Physiology. 12, 2020 | Pubmed ID: 32916040 Inducible Deletion of Skeletal Muscle AMPKα Reveals That AMPK is Required for Nucleotide Balance but Dispensable for Muscle Glucose Uptake and Fat Oxidation During Exercise Molecular Metabolism. 10, 2020 | Pubmed ID: 32504885 A Single Bout of One-Legged Exercise to Local Exhaustion Decreases Insulin Action in Nonexercised Muscle Leading to Decreased Whole-Body Insulin Action Diabetes. 04, 2020 | Pubmed ID: 31974138 Metformin Does Not Compromise Energy Status in Human Skeletal Muscle at Rest or During Acute Exercise: A Randomised, Crossover Trial Physiological Reports. 12, 2019 | Pubmed ID: 31833226 AMPK and TBC1D1 Regulate Muscle Glucose Uptake After, but Not During, Exercise and Contraction Diabetes. 07, 2019 | Pubmed ID: 31010958 ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations Diabetes. 03, 2019 | Pubmed ID: 30626608 Exercise Training Reduces the Insulin-sensitizing Effect of a Single Bout of Exercise in Human Skeletal Muscle The Journal of Physiology. 01, 2019 | Pubmed ID: 30325018 Exercise-induced Molecular Mechanisms Promoting Glycogen Supercompensation in Human Skeletal Muscle Molecular Metabolism. 10, 2018 | Pubmed ID: 30093357 Kinase Activity Determination of Specific AMPK Complexes/Heterotrimers in the Skeletal Muscle Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29480478 Identifying the Heterotrimeric Complex Stoichiometry of AMPK in Skeletal Muscle by Immunoprecipitation Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29480477 Glucose Metabolism and Metabolic Flexibility in Cultured Skeletal Muscle Cells is Related to Exercise Status in Young Male Subjects Archives of Physiology and Biochemistry. May, 2018 | Pubmed ID: 28862046 Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK Diabetes. 03, 2017 | Pubmed ID: 27797909 Intact Regulation of the AMPK Signaling Network in Response to Exercise and Insulin in Skeletal Muscle of Male Patients With Type 2 Diabetes: Illumination of AMPK Activation in Recovery From Exercise Diabetes. 05, 2016 | Pubmed ID: 26822091 Human Muscle Fibre Type-specific Regulation of AMPK and Downstream Targets by Exercise The Journal of Physiology. Apr, 2015 | Pubmed ID: 25640469 AMPKα is Critical for Enhancing Skeletal Muscle Fatty Acid Utilization During in Vivo Exercise in Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2015 | Pubmed ID: 25609422 Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-dependent Manner Diabetes. Jun, 2015 | Pubmed ID: 25552597 Human Muscle Fiber Type-specific Insulin Signaling: Impact of Obesity and Type 2 Diabetes Diabetes. Feb, 2015 | Pubmed ID: 25187364 Acute Exercise and Physiological Insulin Induce Distinct Phosphorylation Signatures on TBC1D1 and TBC1D4 Proteins in Human Skeletal Muscle The Journal of Physiology. Jan, 2014 | Pubmed ID: 24247980 Akt2 Influences Glycogen Synthase Activity in Human Skeletal Muscle Through Regulation of NH₂-terminal (sites 2 + 2a) Phosphorylation American Journal of Physiology. Endocrinology and Metabolism. Mar, 2013 | Pubmed ID: 23321478 Exercise-induced AMPK Activity in Skeletal Muscle: Role in Glucose Uptake and Insulin Sensitivity Molecular and Cellular Endocrinology. Feb, 2013 | Pubmed ID: 22796442 Exercise Alleviates Lipid-induced Insulin Resistance in Human Skeletal Muscle-signaling Interaction at the Level of TBC1 Domain Family Member 4 Diabetes. Nov, 2012 | Pubmed ID: 22851577 Lipid-induced Insulin Resistance Affects Women Less Than Men and is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling Diabetes. Jan, 2011 | Pubmed ID: 20956497 Exercise-induced TBC1D1 Ser237 Phosphorylation and 14-3-3 Protein Binding Capacity in Human Skeletal Muscle The Journal of Physiology. Nov, 2010 | Pubmed ID: 20837646 Low Muscle Glycogen and Elevated Plasma Free Fatty Acid Modify but Do Not Prevent Exercise-induced PDH Activation in Human Skeletal Muscle Diabetes. Jan, 2010 | Pubmed ID: 19833896 Genetic and Metabolic Effects on Skeletal Muscle AMPK in Young and Older Twins American Journal of Physiology. Endocrinology and Metabolism. Oct, 2009 | Pubmed ID: 19671840 A-769662 Activates AMPK Beta1-containing Complexes but Induces Glucose Uptake Through a PI3-kinase-dependent Pathway in Mouse Skeletal Muscle American Journal of Physiology. Cell Physiology. Oct, 2009 | Pubmed ID: 19657063 Genetic Impairment of AMPKalpha2 Signaling Does Not Reduce Muscle Glucose Uptake During Treadmill Exercise in Mice American Journal of Physiology. Endocrinology and Metabolism. Oct, 2009 | Pubmed ID: 19654283 Genetic Disruption of AMPK Signaling Abolishes Both Contraction- and Insulin-stimulated TBC1D1 Phosphorylation and 14-3-3 Binding in Mouse Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. Sep, 2009 | Pubmed ID: 19531644 Reduced Malonyl-CoA Content in Recovery from Exercise Correlates with Improved Insulin-stimulated Glucose Uptake in Human Skeletal Muscle American Journal of Physiology. Endocrinology and Metabolism. Apr, 2009 | Pubmed ID: 19190265 Regulation of PDH in Human Arm and Leg Muscles at Rest and During Intense Exercise American Journal of Physiology. Endocrinology and Metabolism. Jan, 2008 | Pubmed ID: 17957032 Absence of Humoral Mediated 5'AMP-activated Protein Kinase Activation in Human Skeletal Muscle and Adipose Tissue During Exercise The Journal of Physiology. Dec, 2007 | Pubmed ID: 17962330 AS160 Phosphorylation is Associated with Activation of Alpha2beta2gamma1- but Not Alpha2beta2gamma3-AMPK Trimeric Complex in Skeletal Muscle During Exercise in Humans American Journal of Physiology. Endocrinology and Metabolism. Mar, 2007 | Pubmed ID: 17077344 Oral Glucose Ingestion Attenuates Exercise-induced Activation of 5'-AMP-activated Protein Kinase in Human Skeletal Muscle Biochemical and Biophysical Research Communications. Apr, 2006 | Pubmed ID: 16598851 Effects of Alpha-AMPK Knockout on Exercise-induced Gene Activation in Mouse Skeletal Muscle FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2005 | Pubmed ID: 15878932 5'AMP Activated Protein Kinase Expression in Human Skeletal Muscle: Effects of Strength Training and Type 2 Diabetes The Journal of Physiology. Apr, 2005 | Pubmed ID: 15718261 The Alpha2-5'AMP-activated Protein Kinase is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and is Responsive to Glucose Loading Diabetes. Dec, 2004 | Pubmed ID: 15561936 Exercise Signalling to Glucose Transport in Skeletal Muscle The Proceedings of the Nutrition Society. May, 2004 | Pubmed ID: 15294032 Knockout of the Alpha2 but Not Alpha1 5'-AMP-activated Protein Kinase Isoform Abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14573616 Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice Rasmus Kjøbsted1, Kohei Kido1, Jeppe K. Larsen1, Nicolas O. Jørgensen1, Jesper B. Birk1, Ylva Hellsten2, Jørgen F. P. Wojtaszewski1 1Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Section of Integrative Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen JoVE 61398 Biology
Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice Rasmus Kjøbsted1, Kohei Kido1, Jeppe K. Larsen1, Nicolas O. Jørgensen1, Jesper B. Birk1, Ylva Hellsten2, Jørgen F. P. Wojtaszewski1 1Section of Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Section of Integrative Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen JoVE 61398 Biology
