Jessica Perazzelli Division of Oncology, Department of Pediatrics Children’s Hospital of Philadelphia Biography Publications Institution JoVE Articles Jessica Perazzelli has not added a biography. If you are Jessica Perazzelli and would like to personalize this page please email our Author Liaison for assistance. Publications Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy Through Deep Genomic Sequencing Cancer Immunology Research. Jan, 2023 | Pubmed ID: 36255409 Correction for Bagashev Et Al., "CD19 Alterations Emerging After CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum" Molecular and Cellular Biology. Sep, 2022 | Pubmed ID: 35976030 Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2022 | Pubmed ID: 35705524 Antigen-independent Activation Enhances the Efficacy of 4-1BB-costimulated CD22 CAR T Cells Nature Medicine. 05, 2021 | Pubmed ID: 33888899 A Cellular Antidote to Specifically Deplete Anti-CD19 Chimeric Antigen Receptor-positive Cells Blood. Feb, 2020 | Pubmed ID: 31703119 Purification of MRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response Human Gene Therapy. Feb, 2019 | Pubmed ID: 30024272 CD19 Alterations Emerging After CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum Molecular and Cellular Biology. Nov, 2018 | Pubmed ID: 30104252 Dual CD19 and CD123 Targeting Prevents Antigen-loss Relapses After CD19-directed Immunotherapies The Journal of Clinical Investigation. Aug, 2016 | Pubmed ID: 27571406 Early Memory Phenotypes Drive T Cell Proliferation in Patients with Pediatric Malignancies Science Translational Medicine. Jan, 2016 | Pubmed ID: 26738796 Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy Cancer Discovery. Dec, 2015 | Pubmed ID: 26516065 Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 Medicine
Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 Medicine