John M. Ashton Wilmot Cancer Institute University of Rochester Medical Center Biography Publications Institution JoVE Articles John M. Ashton has not added a biography. If you are John M. Ashton and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of a Vitamin-D Receptor Antagonist, MeTC7, Which Inhibits the Growth of Xenograft and Transgenic Tumors Journal of Medicinal Chemistry. Apr, 2022 | Pubmed ID: 35404047 Altered TGFB1 Regulated Pathways Promote Accelerated Tendon Healing in the Superhealer MRL/MpJ Mouse Scientific Reports. Feb, 2022 | Pubmed ID: 35194136 Comparative Analysis of Single-Cell RNA Sequencing Platforms and Methods Journal of Biomolecular Techniques : JBT. Dec, 2021 | Pubmed ID: 35837267 Scaffold-mediated CRISPR-Cas9 Delivery System for Acute Myeloid Leukemia Therapy Science Advances. May, 2021 | Pubmed ID: 34138728 A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups Journal of Biomolecular Techniques : JBT. Apr, 2020 | Pubmed ID: 31969795 Decellularized Wharton Jelly Matrix: a Biomimetic Scaffold for Ex Vivo Hematopoietic Stem Cell Culture Blood Advances. Apr, 2019 | Pubmed ID: 30940636 ARID1A, a SWI/SNF Subunit, is Critical to Acinar Cell Homeostasis and Regeneration and is a Barrier to Transformation and Epithelial-mesenchymal Transition in the Pancreas Gut. Jul, 2019 | Pubmed ID: 30228219 Targeting the Gut Microbiome to Treat the Osteoarthritis of Obesity JCI Insight. Apr, 2018 | Pubmed ID: 29669931 T Cell Developmental Arrest in Former Premature Infants Increases Risk of Respiratory Morbidity Later in Infancy JCI Insight. Feb, 2018 | Pubmed ID: 29467329 Developmental Alcohol Exposure Impairs Synaptic Plasticity Without Overtly Altering Microglial Function in Mouse Visual Cortex Brain, Behavior, and Immunity. Jan, 2018 | Pubmed ID: 28918081 Index Case of Acute Myeloid Leukemia in a Family Harboring a Novel Germ Line Mutation Blood Advances. Mar, 2017 | Pubmed ID: 29296967 Targeted Therapy for a Subset of Acute Myeloid Leukemias That Lack Expression of Aldehyde Dehydrogenase 1A1 Haematologica. Jun, 2017 | Pubmed ID: 28280079 Evolution of Acute Myelogenous Leukemia Stem Cell Properties Following Treatment and Progression Blood. Jul, 2016 | Pubmed ID: 27421961 Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche Cell Stem Cell. Jul, 2016 | Pubmed ID: 27374788 Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia PloS One. 2015 | Pubmed ID: 26177509 BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells Cell Stem Cell. Mar, 2013 | Pubmed ID: 23333149 Gene Sets Identified with Oncogene Cooperativity Analysis Regulate in Vivo Growth and Survival of Leukemia Stem Cells Cell Stem Cell. Sep, 2012 | Pubmed ID: 22863534 Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies (Video) | JoVE Christina M. Kaszuba1,2, Benjamin J. Rodems1,3, Sonali Sharma1,3, Edgardo I. Franco1,2, John M. Ashton1,3,4, Laura M. Calvi1,5, Jeevisha Bajaj1,3 1Wilmot Cancer Institute, University of Rochester Medical Center, 2Department of Biomedical Engineering, University of Rochester, 3Department of Biomedical Genetics, University of Rochester Medical Center, 4Genomics Research Center, University of Rochester Medical Center, 5Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center JoVE 66093 Cancer Research
Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies (Video) | JoVE Christina M. Kaszuba1,2, Benjamin J. Rodems1,3, Sonali Sharma1,3, Edgardo I. Franco1,2, John M. Ashton1,3,4, Laura M. Calvi1,5, Jeevisha Bajaj1,3 1Wilmot Cancer Institute, University of Rochester Medical Center, 2Department of Biomedical Engineering, University of Rochester, 3Department of Biomedical Genetics, University of Rochester Medical Center, 4Genomics Research Center, University of Rochester Medical Center, 5Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center JoVE 66093 Cancer Research