John M. Haynes Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences Monash University Biography Publications Institution JoVE Articles John M. Haynes has not added a biography. If you are John M. Haynes and would like to personalize this page please email our Author Liaison for assistance. Publications SIRPA, VCAM1 and CD34 Identify Discrete Lineages During Early Human Cardiovascular Development Stem Cell Research. Jul, 2014 | Pubmed ID: 24968096 Pulmonary Administration of a Doxorubicin-conjugated Dendrimer Enhances Drug Exposure to Lung Metastases and Improves Cancer Therapy Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2014 | Pubmed ID: 24637466 DNA-dependent Protein Kinase is a Context Dependent Regulator of Lmx1a and Midbrain Specification PloS One. 2013 | Pubmed ID: 24194952 Characterization of Forebrain Neurons Derived from Late-onset Huntington's Disease Human Embryonic Stem Cell Lines Frontiers in Cellular Neuroscience. 2013 | Pubmed ID: 23576953 Synthesis and Biological Evaluation of Adenosines with Heterobicyclic and Polycyclic N(6)-substituents As Adenosine A(1) Receptor Agonists ChemMedChem. Jul, 2012 | Pubmed ID: 22684887 Lmx1a Allows Context-specific Isolation of Progenitors of GABAergic or Dopaminergic Neurons During Neural Differentiation of Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jul, 2012 | Pubmed ID: 22495882 Synthesis and Pharmacological Evaluation of Dual Acting Antioxidant A(2A) Adenosine Receptor Agonists Journal of Medicinal Chemistry. Apr, 2012 | Pubmed ID: 22432713 In Vitro Maturation of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Implications for Transplantation PloS One. 2012 | Pubmed ID: 22384125 NKX2-5(eGFP/w) HESCs for Isolation of Human Cardiac Progenitors and Cardiomyocytes Nature Methods. Dec, 2011 | Pubmed ID: 22020065 Contractions of the Mouse Prostate Elicited by Acetylcholine Are Mediated by M(3) Muscarinic Receptors The Journal of Pharmacology and Experimental Therapeutics. Dec, 2011 | Pubmed ID: 21885618 Extended Periods of Neural Induction and Propagation of Embryonic Stem Cell-derived Neural Progenitors with EGF and FGF2 Enhances Lmx1a Expression and Neurogenic Potential Neurochemistry International. Sep, 2011 | Pubmed ID: 21624410 Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During in Vitro Differentiation of Embryonic Stem Cells Stem Cells (Dayton, Ohio). Jun, 2011 | Pubmed ID: 21472823 A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives Stem Cells (Dayton, Ohio). Mar, 2011 | Pubmed ID: 21425409 The Residual Nonadrenergic Contractile Response to Nerve Stimulation of the Mouse Prostate is Mediated by Acetylcholine but Not ATP in a Comparison with the Mouse Vas Deferens The Journal of Pharmacology and Experimental Therapeutics. Nov, 2010 | Pubmed ID: 20724483 A Novel Highly Selective Adenosine A1 Receptor Agonist VCP28 Reduces Ischemia Injury in a Cardiac Cell Line and Ischemia-reperfusion Injury in Isolated Rat Hearts at Concentrations That Do Not Affect Heart Rate Journal of Cardiovascular Pharmacology. Sep, 2010 | Pubmed ID: 20571427 Androgens Regulate Adenylate Cyclase Activity and Intracellular Calcium in Stromal Cells Derived from Human Prostate The Prostate. Aug, 2010 | Pubmed ID: 20564424 Troubleshooting Immunohistochemical Labelling of Proliferating Cell Nuclear Antigen (PCNA) in Cryocut Tissue Sections of Mouse Prostate Journal of Pharmacological and Toxicological Methods. Mar-Apr, 2010 | Pubmed ID: 19945538 Systemic Stem Cell Improvement in Cardiac Function After Ischaemic Injury: Leaping Forward Slowly Clinical and Experimental Pharmacology & Physiology. Feb, 2008 | Pubmed ID: 18197889 Embryonic Stem Cells As a Source of Models for Drug Discovery Nature Reviews. Drug Discovery. Aug, 2007 | Pubmed ID: 17667955 Beta(2) and Beta(3)-adrenoceptor Inhibition of Alpha(1)-adrenoceptor-stimulated Ca(2+) Elevation in Human Cultured Prostatic Stromal Cells European Journal of Pharmacology. Sep, 2007 | Pubmed ID: 17617401 Heterogeneous Population of Dopaminergic Neurons Derived from Mouse Embryonic Stem Cells: Preliminary Phenotyping Based on Receptor Expression and Function The European Journal of Neuroscience. Apr, 2007 | Pubmed ID: 17419751 Phosphorylation of the PKG Substrate, Vasodilator-stimulated Phosphoprotein (VASP), in Human Cultured Prostatic Stromal Cells Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. Feb, 2007 | Pubmed ID: 17049286 Protein Kinase G-induced Activation of K(ATP) Channels Reduces Contractility of Human Prostate Tissue The Prostate. Mar, 2006 | Pubmed ID: 16302263 Saw Palmetto is an Indirectly Acting Sympathomimetic in the Rat-isolated Prostate Gland The Prostate. Feb, 2006 | Pubmed ID: 16114061 Pharmaceutical Applications of Embryonic Stem Cells Advanced Drug Delivery Reviews. Dec, 2005 | Pubmed ID: 16290153 Current Models of Human Prostate Contractility Clinical and Experimental Pharmacology & Physiology. Oct, 2005 | Pubmed ID: 16173939 Protein Kinase G II-mediated Proliferative Effects in Human Cultured Prostatic Stromal Cells Cellular Signalling. Feb, 2004 | Pubmed ID: 14636895 Purinoceptor-mediated Contractility of the Perfused Uterine Vasculature of the Guinea-pig: Influence of Oestradiol and Pregnancy Clinical and Experimental Pharmacology & Physiology. May-Jun, 2003 | Pubmed ID: 12859422 Protein Kinase G Activation of K(ATP) Channels in Human-cultured Prostatic Stromal Cells Cellular Signalling. Dec, 2002 | Pubmed ID: 12359308 Phorbol Ester-induced Contractility and Ca2+ Influx in Human Cultured Prostatic Stromal Cells Biochemical Pharmacology. Aug, 2002 | Pubmed ID: 12147289 Zinc-finger Nuclease Enhanced Gene Targeting in Human Embryonic Stem Cells Brigham J. Hartley1, Stewart A. Fabb1, Ben A.L. Finnin1, John M. Haynes1, Colin W. Pouton1 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University JoVE 51764 Biology
Zinc-finger Nuclease Enhanced Gene Targeting in Human Embryonic Stem Cells Brigham J. Hartley1, Stewart A. Fabb1, Ben A.L. Finnin1, John M. Haynes1, Colin W. Pouton1 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University JoVE 51764 Biology