John Greenwood

Publications

• LRG1 As a Novel Therapeutic Target in Eye Disease
  Eye (London, England). Jan, 2022  |   Pubmed ID: 34987199
• Eye Movements Elevate Crowding in Idiopathic Infantile Nystagmus Syndrome
  Journal of Vision. Dec, 2021  |   Pubmed ID: 34935877
• CCL4 Induces Inflammatory Signalling and Barrier Disruption in the Neurovascular Endothelium
  Brain, Behavior, & Immunity - Health. Dec, 2021  |   Pubmed ID: 34755124
• Phenotyping Hypertrophic Cardiomyopathy Using Cardiac Diffusion Magnetic Resonance Imaging: the Relationship Between Microvascular Dysfunction and Microstructural Changes
  European Heart Journal. Cardiovascular Imaging. Oct, 2021  |   Pubmed ID: 34694365
• Effect of Remote Ischaemic Conditioning on Infarct Size and Remodelling in ST-segment Elevation Myocardial Infarction Patients: the CONDI-2/ERIC-PPCI CMR Substudy
  Basic Research in Cardiology. 10, 2021  |   Pubmed ID: 34648075
• The "Neuro-Glial-Vascular" Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction
  Frontiers in Cell and Developmental Biology. 2021  |   Pubmed ID: 34646826
• Leucine-rich Alpha-2-glycoprotein 1 (LRG1) As a Novel ADC Target
  RSC Chemical Biology. Aug, 2021  |   Pubmed ID: 34458833
• Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis
  Journal of the American College of Cardiology. 08, 2021  |   Pubmed ID: 34353531
• Heritable Functional Architecture in Human Visual Cortex
  NeuroImage. 10, 2021  |   Pubmed ID: 34153449
• Demographic, Multi-morbidity and Genetic Impact on Myocardial Involvement and Its Recovery from COVID-19: Protocol Design of COVID-HEART-a UK, Multicentre, Observational Study
  Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance. 06, 2021  |   Pubmed ID: 34112195
• Prospective Case-Control Study of Cardiovascular Abnormalities 6 Months Following Mild COVID-19 In Healthcare Workers
  JACC. Cardiovascular Imaging. 11, 2021  |   Pubmed ID: 33975819
• Regional Variation in Cardiovascular Magnetic Resonance Service Delivery Across the UK
  Heart (British Cardiac Society). 12, 2021  |   Pubmed ID: 33766986
• Diagnosis and Risk Stratification in Hypertrophic Cardiomyopathy Using Machine Learning Wall Thickness Measurement: a Comparison with Human Test-retest Performance
  The Lancet. Digital Health. 01, 2021  |   Pubmed ID: 33735065
• Topographical Response of Retinal Neovascularization to Aflibercept or Panretinal Photocoagulation in Proliferative Diabetic Retinopathy: Post Hoc Analysis of the CLARITY Randomized Clinical Trial
  JAMA Ophthalmology. May, 2021  |   Pubmed ID: 33704351
• Small-molecule Antagonist of VLA-4 (GW559090) Attenuated Neuro-inflammation by Targeting Th17 Cell Trafficking Across the Blood-retinal Barrier in Experimental Autoimmune Uveitis
  Journal of Neuroinflammation. Feb, 2021  |   Pubmed ID: 33602234
• Endothelial Protease Activated Receptor 1 (PAR1) Signalling Is Required for Lymphocyte Transmigration Across Brain Microvascular Endothelial Cells
  Cells. 12, 2020  |   Pubmed ID: 33371217
• Evaluation of Real-world Early Response of DMO to Aflibercept Therapy to Inform Future Clinical Trial Design of Novel Investigational Agents
  Scientific Reports. 10, 2020  |   Pubmed ID: 33020570
• A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions
  Diabetes. 11, 2020  |   Pubmed ID: 32887674
• T Mapping Performance and Measurement Repeatability: Results from the Multi-national T Mapping Standardization Phantom Program (T1MES)
  Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance. 05, 2020  |   Pubmed ID: 32375896
• Dissociable Effects of Visual Crowding on the Perception of Color and Motion
  Proceedings of the National Academy of Sciences of the United States of America. 04, 2020  |   Pubmed ID: 32193344
• Extracellular Myocardial Volume in Patients With Aortic Stenosis
  Journal of the American College of Cardiology. 01, 2020  |   Pubmed ID: 31976869
• A Multicenter, Scan-Rescan, Human and Machine Learning CMR Study to Test Generalizability and Precision in Imaging Biomarker Analysis
  Circulation. Cardiovascular Imaging. 10, 2019  |   Pubmed ID: 31547689
• Effect of Remote Ischaemic Conditioning on Clinical Outcomes in Patients with Acute Myocardial Infarction (CONDI-2/ERIC-PPCI): a Single-blind Randomised Controlled Trial
  Lancet (London, England). 10, 2019  |   Pubmed ID: 31500849
• Sex Differences in Left Ventricular Remodelling, Myocardial Fibrosis and Mortality After Aortic Valve Replacement
  Heart (British Cardiac Society). 12, 2019  |   Pubmed ID: 31467152
• Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease
  The New England Journal of Medicine. 06, 2019  |   Pubmed ID: 31216398
• Population Receptive Field Estimates for Motion-defined Stimuli
  NeuroImage. 10, 2019  |   Pubmed ID: 31158480
• Applying Causal Models to Explore the Mechanism of Action of Simvastatin in Progressive Multiple Sclerosis
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2019  |   Pubmed ID: 31072935
• Rationale and Design of the Randomized, Controlled Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients with Severe Aortic Stenosis (EVOLVED) Trial
  American Heart Journal. 06, 2019  |   Pubmed ID: 30978556
• Mineralocorticoid Receptor Antagonist Pre-treatment and Early Post-treatment to Minimize Reperfusion Injury After ST-elevation Myocardial Infarction: The MINIMIZE STEMI Trial
  American Heart Journal. 05, 2019  |   Pubmed ID: 30893577
• Crowding for Faces is Determined by Visual (not Holistic) Similarity: Evidence from Judgements of Eye Position
  Scientific Reports. 08, 2018  |   Pubmed ID: 30135454
• Myocardial Scar and Mortality in Severe Aortic Stenosis
  Circulation. 10, 2018  |   Pubmed ID: 30002099
• Correction To: Current Research into Brain Barriers and the Delivery of Therapeutics for Neurological Diseases: a Report on CNS Barrier Congress London, UK, 2017
  Fluids and Barriers of the CNS. 01, 2018  |   Pubmed ID: 29329565
• Computational Tools for Clinical Support: a Multi-scale Compliant Model for Haemodynamic Simulations in an Aortic Dissection Based on Multi-modal Imaging Data
  Journal of the Royal Society, Interface. 11, 2017  |   Pubmed ID: 29118115
• Current Research into Brain Barriers and the Delivery of Therapeutics for Neurological Diseases: a Report on CNS Barrier Congress London, UK, 2017
  Fluids and Barriers of the CNS. Nov, 2017  |   Pubmed ID: 29110676
• Binocular Therapy for Childhood Amblyopia Improves Vision Without Breaking Interocular Suppression
  Investigative Ophthalmology & Visual Science. 06, 2017  |   Pubmed ID: 28614556
• Variations in Crowding, Saccadic Precision, and Spatial Localization Reveal the Shared Topology of Spatial Vision
  Proceedings of the National Academy of Sciences of the United States of America. 04, 2017  |   Pubmed ID: 28396415
• Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions
  Journal of Immunology (Baltimore, Md. : 1950). 05, 2017  |   Pubmed ID: 28373581
• Comparison of Exercise Testing and CMR Measured Myocardial Perfusion Reserve for Predicting Outcome in Asymptomatic Aortic Stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study
  European Heart Journal. Apr, 2017  |   Pubmed ID: 28204448
• Infarct Size Following Complete Revascularization in Patients Presenting with STEMI: a Comparison of Immediate and Staged In-hospital Non-infarct Related Artery PCI Subgroups in the CvLPRIT Study
  Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance. Nov, 2016  |   Pubmed ID: 27842548
• The Orientation Selectivity of Face Identification
  Scientific Reports. Sep, 2016  |   Pubmed ID: 27677359
• Childhood Amblyopia: Current Management and New Trends
  British Medical Bulletin. 09, 2016  |   Pubmed ID: 27543498
• Cortical Idiosyncrasies Predict the Perception of Object Size
  Nature Communications. 06, 2016  |   Pubmed ID: 27357864
• Infarct Size Following Treatment With Second- Versus Third-Generation P2Y12 Antagonists in Patients With Multivessel Coronary Disease at ST-Segment Elevation Myocardial Infarction in the CvLPRIT Study
  Journal of the American Heart Association. 05, 2016  |   Pubmed ID: 27247336
• Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours
  Ecancermedicalscience. 2016  |   Pubmed ID: 27110286
• Categorical Information Influences Conscious Perception: An Interaction Between Object-substitution Masking and Repetition Blindness
  Attention, Perception & Psychophysics. 05, 2016  |   Pubmed ID: 26902249
• Complete Versus Lesion-Only Primary PCI: The Randomized Cardiovascular MR CvLPRIT Substudy
  Journal of the American College of Cardiology. Dec, 2015  |   Pubmed ID: 26700834
• The Fetal Mouse Metatarsal Bone Explant As a Model of Angiogenesis
  Nature Protocols. Oct, 2015  |   Pubmed ID: 26334866
• Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2015  |   Pubmed ID: 26324770
• Mineralocorticoid Receptor Antagonist Pretreatment to MINIMISE Reperfusion Injury After ST-elevation Myocardial Infarction (the MINIMISE STEMI Trial): Rationale and Study Design
  Clinical Cardiology. May, 2015  |   Pubmed ID: 25990305
• Splenic Switch-off: A Tool to Assess Stress Adequacy in Adenosine Perfusion Cardiac MR Imaging
  Radiology. Sep, 2015  |   Pubmed ID: 25923223
• Randomized Trial of Complete Versus Lesion-only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease: the CvLPRIT Trial
  Journal of the American College of Cardiology. Mar, 2015  |   Pubmed ID: 25766941
• Foveal Target Repetitions Reduce Crowding
  Journal of Vision. Oct, 2014  |   Pubmed ID: 25294741
• Differential Apicobasal VEGF Signaling at Vascular Blood-neural Barriers
  Developmental Cell. Sep, 2014  |   Pubmed ID: 25175707
• Crowding is Reduced by Onset Transients in the Target Object (but Not in the Flankers)
  Journal of Vision. Aug, 2014  |   Pubmed ID: 25086085
• Probing the Biomechanical Contribution of the Endothelium to Lymphocyte Migration: Diapedesis by the Path of Least Resistance
  Journal of Cell Science. Sep, 2014  |   Pubmed ID: 25002404
• Effect of High-dose Simvastatin on Brain Atrophy and Disability in Secondary Progressive Multiple Sclerosis (MS-STAT): a Randomised, Placebo-controlled, Phase 2 Trial
  Lancet (London, England). Jun, 2014  |   Pubmed ID: 24655729
• Rationale and Design of the PRognostic Importance of MIcrovascular Dysfunction in Asymptomatic Patients with Aortic Stenosis (PRIMID-AS): a Multicentre Observational Study with Blinded Investigations
  BMJ Open. Dec, 2013  |   Pubmed ID: 24353258
• Visual Acuity, Crowding, and Stereo-vision Are Linked in Children with and Without Amblyopia
  Investigative Ophthalmology & Visual Science. Nov, 2012  |   Pubmed ID: 23074213
• Number and Density Discrimination Rely on a Common Metric: Similar Psychophysical Effects of Size, Contrast, and Divided Attention
  Journal of Vision. Jun, 2012  |   Pubmed ID: 22665458
• The Neural Correlates of Crowding-induced Changes in Appearance
  Current Biology : CB. Jul, 2012  |   Pubmed ID: 22658599
• Crowding Follows the Binding of Relative Position and Orientation
  Journal of Vision. Mar, 2012  |   Pubmed ID: 22438467
• Apelin is Required for Non-neovascular Remodeling in the Retina
  The American Journal of Pathology. Jan, 2012  |   Pubmed ID: 22067912
• A Common Visual Metric for Approximate Number and Density
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011  |   Pubmed ID: 22106276
• Crowding is Tuned for Perceived (not Physical) Location
  Journal of Vision. Aug, 2011  |   Pubmed ID: 21824980
• The Expression of Retinal Cell Markers in Human Retinal Pigment Epithelial Cells and Their Augmentation by the Synthetic Retinoid Fenretinide
  Molecular Vision. 2011  |   Pubmed ID: 21738400
• Review: Leucocyte-endothelial Cell Crosstalk at the Blood-brain Barrier: a Prerequisite for Successful Immune Cell Entry to the Brain
  Neuropathology and Applied Neurobiology. Feb, 2011  |   Pubmed ID: 20946472
• Analysis of Candidate Genes for Macular Telangiectasia Type 2
  Molecular Vision. 2010  |   Pubmed ID: 21179236
• Probabilistic, Positional Averaging Predicts Object-level Crowding Effects with Letter-like Stimuli
  Journal of Vision. Aug, 2010  |   Pubmed ID: 20884479
• Crowding Changes Appearance
  Current Biology : CB. Mar, 2010  |   Pubmed ID: 20206527
• The RhoA Activator GEF-H1/Lfc is a Transforming Growth Factor-beta Target Gene and Effector That Regulates Alpha-smooth Muscle Actin Expression and Cell Migration
  Molecular Biology of the Cell. Mar, 2010  |   Pubmed ID: 20089843
• Genetic Ablation of Retinal Pigment Epithelial Cells Reveals the Adaptive Response of the Epithelium and Impact on Photoreceptors
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009  |   Pubmed ID: 19850870
• Decreased TNF-alpha Synthesis by Macrophages Restricts Cutaneous Immunosurveillance by Memory CD4+ T Cells During Aging
  The Journal of Experimental Medicine. Aug, 2009  |   Pubmed ID: 19667063
• Positional Averaging Explains Crowding with Letter-like Stimuli
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009  |   Pubmed ID: 19617570
• Annexin A2 Regulates Phagocytosis of Photoreceptor Outer Segments in the Mouse Retina
  Molecular Biology of the Cell. Sep, 2009  |   Pubmed ID: 19587120
• ICAM-1-mediated Endothelial Nitric Oxide Synthase Activation Via Calcium and AMP-activated Protein Kinase is Required for Transendothelial Lymphocyte Migration
  Molecular Biology of the Cell. Feb, 2009  |   Pubmed ID: 19073885
• Phosphorylation of Vascular Endothelial Cadherin Controls Lymphocyte Emigration
  Journal of Cell Science. Jan, 2008  |   Pubmed ID: 18096689
• Complement Factor H Deficiency in Aged Mice Causes Retinal Abnormalities and Visual Dysfunction
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007  |   Pubmed ID: 17921253
• Preservation of Visual Cortical Function Following Retinal Pigment Epithelium Transplantation in the RCS Rat Using Optical Imaging Techniques
  The European Journal of Neuroscience. Apr, 2007  |   Pubmed ID: 17439483
• Dopamine Neurones Form a Discrete Plexus with Melanopsin Cells in Normal and Degenerating Retina
  Experimental Neurology. May, 2007  |   Pubmed ID: 17362933
• Statins and the Vascular Endothelial Inflammatory Response
  Trends in Immunology. Feb, 2007  |   Pubmed ID: 17197237
• Statin Therapy and Autoimmune Disease: from Protein Prenylation to Immunomodulation
  Nature Reviews. Immunology. May, 2006  |   Pubmed ID: 16639429
• Pharmacological Targeting of ICAM-1 Signaling in Brain Endothelial Cells: Potential for Treating Neuroinflammation
  Cellular and Molecular Neurobiology. Feb, 2005  |   Pubmed ID: 15962512
• Suppression of Autoimmune Retinal Disease by Lovastatin Does Not Require Th2 Cytokine Induction
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005  |   Pubmed ID: 15699169
• Basement Membrane-dependent Modification of Phenotype and Gene Expression in Human Retinal Pigment Epithelial ARPE-19 Cells
  Investigative Ophthalmology & Visual Science. Aug, 2004  |   Pubmed ID: 15277505
• Oxidative Stress Affects the Junctional Integrity of Retinal Pigment Epithelial Cells
  Investigative Ophthalmology & Visual Science. Feb, 2004  |   Pubmed ID: 14744914
• Intracellular Domain of Brain Endothelial Intercellular Adhesion Molecule-1 is Essential for T Lymphocyte-mediated Signaling and Migration
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2003  |   Pubmed ID: 12902516
• Potential of Statins for the Treatment of Multiple Sclerosis
  The Lancet. Neurology. Jan, 2003  |   Pubmed ID: 12849290
• Changes in Cytoskeletal and Tight Junctional Proteins Correlate with Decreased Permeability Induced by Dexamethasone in Cultured Rat Brain Endothelial Cells
  Neuroscience Letters. Jun, 2003  |   Pubmed ID: 12782340
• Lovastatin Inhibits Brain Endothelial Cell Rho-mediated Lymphocyte Migration and Attenuates Experimental Autoimmune Encephalomyelitis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2003  |   Pubmed ID: 12626426
• Lymphocyte Migration into the Central Nervous System: Implication of ICAM-1 Signalling at the Blood-brain Barrier
  Vascular Pharmacology. Jun, 2002  |   Pubmed ID: 12529926
• Ezrin and Moesin Co-localise with ICAM-1 in Brain Endothelial Cells but Are Not Directly Associated
  Brain Research. Molecular Brain Research. Sep, 2002  |   Pubmed ID: 12399107
• Lymphocyte Trafficking Through the Blood-brain Barrier is Dependent on Endothelial Cell Heterotrimeric G-protein Signaling
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2002  |   Pubmed ID: 12153986
• Inhibition of Rho GTPases with Protein Prenyltransferase Inhibitors Prevents Leukocyte Recruitment to the Central Nervous System and Attenuates Clinical Signs of Disease in an Animal Model of Multiple Sclerosis
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2002  |   Pubmed ID: 11937568
• Characterization of Genetically Modified Human Retinal Pigment Epithelial Cells Developed for in Vitro and Transplantation Studies
  Investigative Ophthalmology & Visual Science. Feb, 2002  |   Pubmed ID: 11818403
• Subretinal Transplantation of Genetically Modified Human Cell Lines Attenuates Loss of Visual Function in Dystrophic Rats
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2001  |   Pubmed ID: 11504951
• SV40 Large T Immortalised Cell Lines of the Rat Blood-brain and Blood-retinal Barriers Retain Their Phenotypic and Immunological Characteristics
  Journal of Neuroimmunology. Dec, 1996  |   Pubmed ID: 8982103