Joshua D. Webster Department of Pathology Genentech Biography Publications Institution JoVE Articles Joshua D. Webster has not added a biography. If you are Joshua D. Webster and would like to personalize this page please email our Author Liaison for assistance. Publications Reporting Guidelines for Manuscripts on Tumor Prognosis Veterinary Pathology. 05, 2022 | Pubmed ID: 35220838 Shigella Ubiquitin Ligase IpaH7.8 Targets Gasdermin D for Degradation to Prevent Pyroptosis and Enable Infection Cell Host & Microbe. 10, 2021 | Pubmed ID: 34492225 Genetic Inactivation of RIP1 Kinase Activity in Rats Protects Against Ischemic Brain Injury Cell Death & Disease. 04, 2021 | Pubmed ID: 33828080 NINJ1 Mediates Plasma Membrane Rupture During Lytic Cell Death Nature. 03, 2021 | Pubmed ID: 33472215 Impaired RIPK1 Ubiquitination Sensitizes Mice to TNF Toxicity and Inflammatory Cell Death Cell Death and Differentiation. 03, 2021 | Pubmed ID: 32999468 Genetic Inactivation of RIP1 Kinase Does Not Ameliorate Disease in a Mouse Model of ALS Cell Death and Differentiation. 03, 2021 | Pubmed ID: 32994544 Integration of Innate Immune Signalling by Caspase-8 Cleavage of N4BP1 Nature. 11, 2020 | Pubmed ID: 32971525 Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading C/EBPβ in Microglia Cell. 09, 2020 | Pubmed ID: 32795415 The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32671059 Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury Journal of the American Society of Nephrology : JASN. 10, 2020 | Pubmed ID: 32651223 MAP4K4 Negatively Regulates CD8 T Cell-mediated Antitumor and Antiviral Immunity Science Immunology. 03, 2020 | Pubmed ID: 32220977 The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma Cancer Research. 04, 2020 | Pubmed ID: 31988076 RIP1 Kinase Activity is Critical for Skin Inflammation but Not for Viral Propagation Journal of Leukocyte Biology. 06, 2020 | Pubmed ID: 31985117 Applications and Considerations for the Use of Genetically Engineered Mouse Models in Drug Development Cell and Tissue Research. May, 2020 | Pubmed ID: 31486957 Unobstructed Multiscale Imaging of Tissue Sections for Ultrastructural Pathology Analysis by Backscattered Electron Scanning Microscopy The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 01, 2020 | Pubmed ID: 31385742 RIP1 Inhibition Blocks Inflammatory Diseases but Not Tumor Growth or Metastases Cell Death and Differentiation. 01, 2020 | Pubmed ID: 31101885 Activity of Caspase-8 Determines Plasticity Between Cell Death Pathways Nature. 11, 2019 | Pubmed ID: 31723262 The RIPK4-IRF6 Signalling Axis Safeguards Epidermal Differentiation and Barrier Function Nature. 10, 2019 | Pubmed ID: 31578523 Cleavage of RIPK1 by Caspase-8 is Crucial for Limiting Apoptosis and Necroptosis Nature. 10, 2019 | Pubmed ID: 31511692 Prognostic and Predictive Significance of KIT Protein Expression and C-kit Gene Mutation in Canine Cutaneous Mast Cell Tumours: A Consensus of the Oncology-Pathology Working Group Veterinary and Comparative Oncology. Dec, 2019 | Pubmed ID: 31264352 Ubiquitin Ligases CIAP1 and CIAP2 Limit Cell Death to Prevent Inflammation Cell Reports. 05, 2019 | Pubmed ID: 31141691 Intrinsic Apoptosis Shapes the Tumor Spectrum Linked to Inactivation of the Deubiquitinase BAP1 Science (New York, N.Y.). Apr, 2019 | Pubmed ID: 31000662 The Gag Protein PEG10 Binds to RNA and Regulates Trophoblast Stem Cell Lineage Specification PloS One. 2019 | Pubmed ID: 30951545 The Tumor Suppressor BAP1 Cooperates with BRAFV600E to Promote Tumor Formation in Cutaneous Melanoma Pigment Cell & Melanoma Research. 03, 2019 | Pubmed ID: 30156010 Ubiquitin Ligase COP1 Coordinates Transcriptional Programs That Control Cell Type Specification in the Developing Mouse Brain Proceedings of the National Academy of Sciences of the United States of America. 10, 2018 | Pubmed ID: 30322923 Observational Study Design in Veterinary Pathology, Part 2: Methodology Veterinary Pathology. Sep, 2018 | Pubmed ID: 30227783 The Hippo Pathway Effector TAZ Induces TEAD-dependent Liver Inflammation and Tumors Science Signaling. 09, 2018 | Pubmed ID: 30206136 Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical Labeling Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30136239 Kinase Domain Dimerization Drives RIPK3-dependent Necroptosis Science Signaling. 08, 2018 | Pubmed ID: 30131368 Observational Study Design in Veterinary Pathology, Part 1: Study Design Veterinary Pathology. 09, 2018 | Pubmed ID: 30071806 OTULIN Limits Cell Death and Inflammation by Deubiquitinating LUBAC Nature. 07, 2018 | Pubmed ID: 29950720 Multifaceted Roles of Autophagy in Health and Disease Veterinary Pathology. 05, 2018 | Pubmed ID: 29635994 Coordinated Ubiquitination and Phosphorylation of RIP1 Regulates Necroptotic Cell Death Cell Death and Differentiation. 01, 2017 | Pubmed ID: 27518435 RIPK1 Inhibits ZBP1-driven Necroptosis During Development Nature. 12, 2016 | Pubmed ID: 27819682 Transcriptional Profiling of Canine Mast Cell Tumors: Searching for Candidate Targets and Prognostic Markers Veterinary Journal (London, England : 1997). 08, 2016 | Pubmed ID: 27387731 NeuCode Proteomics Reveals Bap1 Regulation of Metabolism Cell Reports. 07, 2016 | Pubmed ID: 27373151 Inhibition of the Kinase ITK in a Mouse Model of Asthma Reduces Cell Death and Fails to Inhibit the Inflammatory Response Science Signaling. Dec, 2015 | Pubmed ID: 26628680 β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1 Cell. Dec, 2015 | Pubmed ID: 26627735 Small Molecule Kinase Inhibitors in Veterinary Oncology Veterinary Journal (London, England : 1997). Aug, 2015 | Pubmed ID: 25744806 Immunohistochemical Detection of FLAG-tagged Endogenous Proteins in Knock-in Mice The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 04, 2015 | Pubmed ID: 25575566 Regulation of Proximal T Cell Receptor Signaling and Tolerance Induction by Deubiquitinase Usp9X The Journal of Experimental Medicine. Sep, 2014 | Pubmed ID: 25200027 Whole-slide Imaging and Automated Image Analysis: Considerations and Opportunities in the Practice of Pathology Veterinary Pathology. Jan, 2014 | Pubmed ID: 24091812 Standardisert behandling for formalin-faste, parafin-innebygde cellepelletsimmunhistokjemikontroller Charles Havnar1, Kathy Hotzel1, Carmina Espiritu1, Amy Lo1, Joshua D. Webster1 1Department of Pathology, Genentech JoVE 64276 Biology
Standardisert behandling for formalin-faste, parafin-innebygde cellepelletsimmunhistokjemikontroller Charles Havnar1, Kathy Hotzel1, Carmina Espiritu1, Amy Lo1, Joshua D. Webster1 1Department of Pathology, Genentech JoVE 64276 Biology