Kai Kaila Department of Biosciences University of Helsinki Biography Publications Institution JoVE Articles Kai Kaila has not added a biography. If you are Kai Kaila and would like to personalize this page please email our Author Liaison for assistance. Publications Subplate Neurons Promote Spindle Bursts and Thalamocortical Patterning in the Neonatal Rat Somatosensory Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2012 | Pubmed ID: 22238105 Respiratory Alkalosis in Children with Febrile Seizures Epilepsia. Nov, 2011 | Pubmed ID: 21910730 A Prestabilized Harmony Neuron. Jul, 2011 | Pubmed ID: 21791279 Cold-adapted Protease Enables Quantitation of Surface Proteins in the Absence of Membrane Trafficking BioTechniques. Apr, 2011 | Pubmed ID: 21548910 Brain Alkalosis Causes Birth Asphyxia Seizures, Suggesting Therapeutic Strategy Annals of Neurology. Mar, 2011 | Pubmed ID: 21337602 Five Percent COâ‚‚ is a Potent, Fast-acting Inhalation Anticonvulsant Epilepsia. Jan, 2011 | Pubmed ID: 20887367 Spontaneous Network Events Driven by Depolarizing GABA Action in Neonatal Hippocampal Slices Are Not Attributable to Deficient Mitochondrial Energy Metabolism The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21084619 A Single Seizure Episode Leads to Rapid Functional Activation of KCC2 in the Neonatal Rat Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20826666 Polyamines Inhibit Carbonic Anhydrases by Anchoring to the Zinc-coordinated Water Molecule Journal of Medicinal Chemistry. Aug, 2010 | Pubmed ID: 20590092 Premature Expression of KCC2 in Embryonic Mice Perturbs Neural Development by an Ion Transport-independent Mechanism The European Journal of Neuroscience. Jun, 2010 | Pubmed ID: 20529123 The K+-Cl Cotransporter KCC2 Promotes GABAergic Excitation in the Mature Rat Hippocampus The Journal of Physiology. May, 2010 | Pubmed ID: 20211979 Acetazolamide and Midazolam Act Synergistically to Inhibit Neuropathic Pain Pain. Feb, 2010 | Pubmed ID: 20007010 Opposite Effect of Membrane Raft Perturbation on Transport Activity of KCC2 and NKCC1 Journal of Neurochemistry. Oct, 2009 | Pubmed ID: 19686239 Compensatory Enhancement of Intrinsic Spiking Upon NKCC1 Disruption in Neonatal Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009 | Pubmed ID: 19474325 Cation-chloride Cotransporters and Neuronal Function Neuron. Mar, 2009 | Pubmed ID: 19323993 Neurobiological and Physiological Mechanisms of Fever-related Epileptiform Syndromes Brain & Development. May, 2009 | Pubmed ID: 19201562 Posttraumatic GABA(A)-mediated [Ca2+]i Increase is Essential for the Induction of Brain-derived Neurotrophic Factor-dependent Survival of Mature Central Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008 | Pubmed ID: 18596173 GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons is Caused by the Na-K-2Cl Cotransporter NKCC1 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18448640 Generation of 'positive Slow Waves' in the Preterm EEG: by the Brain or by the EEG Setup? Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Jun, 2008 | Pubmed ID: 18406203 Pronounced Increase in Breathing Rate in the "hair Dryer Model" of Experimental Febrile Seizures Epilepsia. May, 2008 | Pubmed ID: 18325016 Development of Hemodynamic Responses and Functional Connectivity in Rat Somatosensory Cortex Nature Neuroscience. Jan, 2008 | Pubmed ID: 18037883 GABAergic Control of CA3-driven Network Events in the Developing Hippocampus Results and Problems in Cell Differentiation. 2008 | Pubmed ID: 17622497 KCC2 Interacts with the Dendritic Cytoskeleton to Promote Spine Development Neuron. Dec, 2007 | Pubmed ID: 18093524 Inhibition and Brain Work Neuron. Dec, 2007 | Pubmed ID: 18054855 Perturbed Chloride Homeostasis and GABAergic Signaling in Human Temporal Lobe Epilepsy The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2007 | Pubmed ID: 17855601 A Novel N-terminal Isoform of the Neuron-specific K-Cl Cotransporter KCC2 The Journal of Biological Chemistry. Oct, 2007 | Pubmed ID: 17715129 Carbonic Anhydrase Activators: Activation of the Human Isoforms VII (cytosolic) and XIV (transmembrane) with Amino Acids and Amines Bioorganic & Medicinal Chemistry Letters. Aug, 2007 | Pubmed ID: 17540561 The Cellular, Molecular and Ionic Basis of GABA(A) Receptor Signalling Progress in Brain Research. 2007 | Pubmed ID: 17499109 GAT-1 Acts to Limit a Tonic GABA(A) Current in Rat CA3 Pyramidal Neurons at Birth The European Journal of Neuroscience. Feb, 2007 | Pubmed ID: 17298599 Development of Neonatal EEG Activity: from Phenomenology to Physiology Seminars in Fetal & Neonatal Medicine. Dec, 2006 | Pubmed ID: 17018268 Experimental Febrile Seizures Are Precipitated by a Hyperthermia-induced Respiratory Alkalosis Nature Medicine. Jul, 2006 | Pubmed ID: 16819552 Intrinsic Bursting of Immature CA3 Pyramidal Neurons and Consequent Giant Depolarizing Potentials Are Driven by a Persistent Na+ Current and Terminated by a Slow Ca2+ -activated K+ Current The European Journal of Neuroscience. May, 2006 | Pubmed ID: 16706841 The Cation-chloride Cotransporter NKCC1 Promotes Sharp Waves in the Neonatal Rat Hippocampus The Journal of Physiology. Jun, 2006 | Pubmed ID: 16644806 Carbonic Anhydrase Inhibitors: Inhibition of the Cytosolic Human Isozyme VII with Anions Bioorganic & Medicinal Chemistry Letters. Jun, 2006 | Pubmed ID: 16621537 Slow Endogenous Activity Transients and Developmental Expression of K+-Cl- Cotransporter 2 in the Immature Human Cortex The European Journal of Neuroscience. Dec, 2005 | Pubmed ID: 16324114 Full-band EEG (fbEEG): a New Standard for Clinical Electroencephalography Clinical EEG and Neuroscience : Official Journal of the EEG and Clinical Neuroscience Society (ENCS). Oct, 2005 | Pubmed ID: 16296449 Depolarizing GABA Acts on Intrinsically Bursting Pyramidal Neurons to Drive Giant Depolarizing Potentials in the Immature Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15930375 Phase Synchrony Among Neuronal Oscillations in the Human Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2005 | Pubmed ID: 15829648 Distinct Properties of Functional KCC2 Expression in Immature Mouse Hippocampal Neurons in Culture and in Acute Slices The European Journal of Neuroscience. Feb, 2005 | Pubmed ID: 15787696 Carbonic Anhydrase Inhibitors. Inhibition of the Human Cytosolic Isozyme VII with Aromatic and Heterocyclic Sulfonamides Bioorganic & Medicinal Chemistry Letters. Feb, 2005 | Pubmed ID: 15686895 Full-band EEG (FbEEG): an Emerging Standard in Electroencephalography Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Jan, 2005 | Pubmed ID: 15589176 Two Developmental Switches in GABAergic Signalling: the K+-Cl- Cotransporter KCC2 and Carbonic Anhydrase CAVII The Journal of Physiology. Jan, 2005 | Pubmed ID: 15528236 GABA Uptake Via GABA Transporter-1 Modulates GABAergic Transmission in the Immature Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15229234 Mechanism of Activity-dependent Downregulation of the Neuron-specific K-Cl Cotransporter KCC2 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004 | Pubmed ID: 15140939 Nonneuronal Origin of CO2-related DC EEG Shifts: an in Vivo Study in the Cat Journal of Neurophysiology. Aug, 2004 | Pubmed ID: 15056689 Carbonic Anhydrase Isoform VII Acts As a Molecular Switch in the Development of Synchronous Gamma-frequency Firing of Hippocampal CA1 Pyramidal Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15028762 Stimulus-induced Change in Long-range Temporal Correlations and Scaling Behaviour of Sensorimotor Oscillations The European Journal of Neuroscience. Jan, 2004 | Pubmed ID: 14750978 Developmental Up-regulation of KCC2 in the Absence of GABAergic and Glutamatergic Transmission The European Journal of Neuroscience. Dec, 2003 | Pubmed ID: 14686894 Vagal Nerve Stimulation Induces Intermittent Hypocapnia Epilepsia. Dec, 2003 | Pubmed ID: 14636333 Cell Type-specific Differences in Chloride-regulatory Mechanisms and GABA(A) Receptor-mediated Inhibition in Rat Substantia Nigra The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2003 | Pubmed ID: 12967985 Post-traumatic Hyperexcitability is Not Caused by Impaired Buffering of Extracellular Potassium The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12843291 Heterogeneous Expression of the Potassium-chloride Cotransporter KCC2 in Gonadotropin-releasing Hormone Neurons of the Adult Mouse Endocrinology. Jul, 2003 | Pubmed ID: 12810559 Cation-chloride Co-transporters in Neuronal Communication, Development and Trauma Trends in Neurosciences. Apr, 2003 | Pubmed ID: 12689771 Millivolt-scale DC Shifts in the Human Scalp EEG: Evidence for a Nonneuronal Generator Journal of Neurophysiology. Apr, 2003 | Pubmed ID: 12612037 Patterns of Cation-chloride Cotransporter Expression During Embryonic Rodent CNS Development The European Journal of Neuroscience. Dec, 2002 | Pubmed ID: 12492431 BDNF-induced TrkB Activation Down-regulates the K+-Cl- Cotransporter KCC2 and Impairs Neuronal Cl- Extrusion The Journal of Cell Biology. Dec, 2002 | Pubmed ID: 12473684 Spontaneous Epileptiform Activity Mediated by GABA(A) Receptors and Gap Junctions in the Rat Hippocampal Slice Following Long-term Exposure to GABA(B) Antagonists Neuropharmacology. Sep, 2002 | Pubmed ID: 12367602 Postnatal Development of Rat Hippocampal Gamma Rhythm in Vivo Journal of Neurophysiology. Sep, 2002 | Pubmed ID: 12205167 Visually Evoked Gamma Responses in the Human Brain Are Enhanced During Voluntary Hyperventilation NeuroImage. Mar, 2002 | Pubmed ID: 11848700 Distinct Gamma-band Evoked Responses to Speech and Non-speech Sounds in Humans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2002 | Pubmed ID: 11844845 Preterm EEG: A Multimodal Neurophysiological Protocol Susanna Stjerna1, Juha Voipio2, Marjo Metsäranta3, Kai Kaila2,4, Sampsa Vanhatalo1 1Department of Children's Clinical Neurophysiology, Helsinki University Hospital, University of Helsinki, 2Department of Biosciences, University of Helsinki, 3Department of Pediatrics, Helsinki University Hospital, University of Helsinki, 4Neuroscience Center, University of Helsinki JoVE 3774 Neuroscience
Preterm EEG: A Multimodal Neurophysiological Protocol Susanna Stjerna1, Juha Voipio2, Marjo Metsäranta3, Kai Kaila2,4, Sampsa Vanhatalo1 1Department of Children's Clinical Neurophysiology, Helsinki University Hospital, University of Helsinki, 2Department of Biosciences, University of Helsinki, 3Department of Pediatrics, Helsinki University Hospital, University of Helsinki, 4Neuroscience Center, University of Helsinki JoVE 3774 Neuroscience