Klaus Bønnelykke Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital University of Copenhagen Biography Publications Institution JoVE Articles Klaus Bønnelykke has not added a biography. If you are Klaus Bønnelykke and would like to personalize this page please email our Author Liaison for assistance. Publications Bivariate Genome-wide Association Meta-analysis of Pediatric Musculoskeletal Traits Reveals Pleiotropic Effects at the SREBF1/TOM1L2 Locus Nature Communications. Jul, 2017 | Pubmed ID: 28743860 Rationale and Design of the Multiethnic Pharmacogenomics in Childhood Asthma Consortium Pharmacogenomics. 07, 2017 | Pubmed ID: 28639505 Investigating the Causal Effect of Smoking on Hay Fever and Asthma: a Mendelian Randomization Meta-analysis in the CARTA Consortium Scientific Reports. May, 2017 | Pubmed ID: 28533558 Precision Allergy: Separate Allergies to Male and Female Dogs The Journal of Allergy and Clinical Immunology. In Practice. May, 2017 | Pubmed ID: 28499775 Sensitization Trajectories in Childhood Revealed by Using a Cluster Analysis The Journal of Allergy and Clinical Immunology. Mar, 2017 | Pubmed ID: 28347735 Fish Oil in Pregnancy and Asthma in Offspring The New England Journal of Medicine. 03, 2017 | Pubmed ID: 28328328 A Rare IL33 Loss-of-function Mutation Reduces Blood Eosinophil Counts and Protects from Asthma PLoS Genetics. Mar, 2017 | Pubmed ID: 28273074 Shared Genetic Variants Suggest Common Pathways in Allergy and Autoimmune Diseases The Journal of Allergy and Clinical Immunology. Feb, 2017 | Pubmed ID: 28188724 No Evidence of Intrauterine Sensitization Against Inhalant Allergens The Journal of Allergy and Clinical Immunology. Jul, 2017 | Pubmed ID: 28040416 Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring The New England Journal of Medicine. 12, 2016 | Pubmed ID: 28029926 Genome-wide Analysis Identifies 12 Loci Influencing Human Reproductive Behavior Nature Genetics. Dec, 2016 | Pubmed ID: 27798627 Genome-wide Associations for Birth Weight and Correlations with Adult Disease Nature. Oct, 2016 | Pubmed ID: 27680694 A Genome-wide Association Meta-analysis of Diarrhoeal Disease in Young Children Identifies FUT2 Locus and Provides Plausible Biological Pathways Human Molecular Genetics. Sep, 2016 | Pubmed ID: 27559109 Genome-wide Association Study Identifies 74 Loci Associated with Educational Attainment Nature. May, 2016 | Pubmed ID: 27225129 Reply The Journal of Allergy and Clinical Immunology. Jul, 2016 | Pubmed ID: 27084400 Cesarean Section Changes Neonatal Gut Colonization The Journal of Allergy and Clinical Immunology. Sep, 2016 | Pubmed ID: 27045582 Leveraging Gene-environment Interactions and Endotypes for Asthma Gene Discovery The Journal of Allergy and Clinical Immunology. Mar, 2016 | Pubmed ID: 26947980 Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria The Pediatric Infectious Disease Journal. May, 2016 | Pubmed ID: 26910587 Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial JAMA. Jan, 2016 | Pubmed ID: 26813208 Azithromycin for Episodes with Asthma-like Symptoms in Young Children Aged 1-3 Years: a Randomised, Double-blind, Placebo-controlled Trial The Lancet. Respiratory Medicine. Jan, 2016 | Pubmed ID: 26704020 Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates The Journal of Infectious Diseases. Apr, 2016 | Pubmed ID: 26655299 Genome-wide Association Analysis Identifies Three New Susceptibility Loci for Childhood Body Mass Index Human Molecular Genetics. Jan, 2016 | Pubmed ID: 26604143 Atopic Endotype in Childhood The Journal of Allergy and Clinical Immunology. Mar, 2016 | Pubmed ID: 26597163 Season of Birth Shapes Neonatal Immune Function The Journal of Allergy and Clinical Immunology. Apr, 2016 | Pubmed ID: 26581916 Multi-ancestry Genome-wide Association Study of 21,000 Cases and 95,000 Controls Identifies New Risk Loci for Atopic Dermatitis Nature Genetics. Dec, 2015 | Pubmed ID: 26482879 Genetics of Allergy and Allergic Sensitization: Common Variants, Rare Mutations Current Opinion in Immunology. Oct, 2015 | Pubmed ID: 26386198 Duration of Wheezy Episodes in Early Childhood is Independent of the Microbial Trigger The Journal of Allergy and Clinical Immunology. Nov, 2015 | Pubmed ID: 26100088 Prelabor Cesarean Section Bypasses Natural Immune Cell Maturation The Journal of Allergy and Clinical Immunology. Oct, 2015 | Pubmed ID: 26094084 Association Between Respiratory Infections in Early Life and Later Asthma is Independent of Virus Type The Journal of Allergy and Clinical Immunology. Jul, 2015 | Pubmed ID: 25910716 Neonates with Reduced Neonatal Lung Function Have Systemic Low-grade Inflammation The Journal of Allergy and Clinical Immunology. Jun, 2015 | Pubmed ID: 25579483 Postmenopausal Hormone Therapy and Asthma-related Hospital Admission The Journal of Allergy and Clinical Immunology. Mar, 2015 | Pubmed ID: 25579482 Cesarean Section and Chronic Immune Disorders Pediatrics. Jan, 2015 | Pubmed ID: 25452656 A Novel Common Variant in DCST2 is Associated with Length in Early Life and Height in Adulthood Human Molecular Genetics. Feb, 2015 | Pubmed ID: 25281659 Gene-environment Interaction in Atopic Diseases: a Population-based Twin Study of Early-life Exposures The Clinical Respiratory Journal. Jan, 2015 | Pubmed ID: 24444295 Maternal Antibiotic Use and Risk of Asthma in Offspring--Authors' Reply The Lancet. Respiratory Medicine. Oct, 2014 | Pubmed ID: 25298061 Maternal Propensity for Infections and Risk of Childhood Asthma: a Registry-based Cohort Study The Lancet. Respiratory Medicine. Aug, 2014 | Pubmed ID: 25066330 Cord Blood 25(OH)-vitamin D Deficiency and Childhood Asthma, Allergy and Eczema: the COPSAC2000 Birth Cohort Study PloS One. 2014 | Pubmed ID: 24925304 Prenatal and Postnatal Genetic Influence on Lung Function Development The Journal of Allergy and Clinical Immunology. Nov, 2014 | Pubmed ID: 24857373 Effect of Delivery Device on Systemic Exposure to Inhaled Fluticasone Propionate in Children with Asthma British Journal of Clinical Pharmacology. Aug, 2014 | Pubmed ID: 24527946 Fraction of Exhaled Nitric Oxide Values in Childhood Are Associated with 17q11.2-q12 and 17q12-q21 Variants The Journal of Allergy and Clinical Immunology. Jul, 2014 | Pubmed ID: 24315451 A Genome-wide Association Study Identifies CDHR3 As a Susceptibility Locus for Early Childhood Asthma with Severe Exacerbations Nature Genetics. Jan, 2014 | Pubmed ID: 24241537 The PCDH1 Gene and Asthma in Early Childhood The European Respiratory Journal. Mar, 2014 | Pubmed ID: 23988763 [Reply: Allergy is Not Always the Cause of Asthma] Ugeskrift for Laeger. Nov, 2013 | Pubmed ID: 26495471 Prevalence and Predictors of Antibiotic Administration During Pregnancy and Birth PloS One. 2013 | Pubmed ID: 24340068 [Childhood Asthma: Danish Guidelines for Diagnosis and Treatment] Ugeskrift for Laeger. Aug, 2013 | Pubmed ID: 23937873 Meta-analysis of Genome-wide Association Studies Identifies Ten Loci Influencing Allergic Sensitization Nature Genetics. Aug, 2013 | Pubmed ID: 23817571 Aerosol Particle Size Does Not Predict Pharmacokinetic Determined Lung Dose in Children Journal of Clinical Pharmacology. May, 2013 | Pubmed ID: 23553595 Rhinovirus Wheezing Illness and Genetic Risk of Childhood-onset Asthma The New England Journal of Medicine. Apr, 2013 | Pubmed ID: 23534543 Use of Antibiotics During Pregnancy Increases the Risk of Asthma in Early Childhood The Journal of Pediatrics. Apr, 2013 | Pubmed ID: 23140881 Nouveaux Loci Associés à Poids à La Naissance D'identifier Des Liens Génétiques Entre Le Retard De Croissance Intra-utérin Et De Taille Adulte Et De Métabolisme Nature Genetics. Dec, 2012 | Pubmed ID: 23202124 Fraction of Exhaled Nitric Oxide and Bronchial Responsiveness Are Associated and Continuous Traits in Young Children Independent of Asthma Chest. Dec, 2012 | Pubmed ID: 23187857 Living with Cat and Dog Increases Vaginal Colonization with E. Coli in Pregnant Women PloS One. 2012 | Pubmed ID: 23049986 Skin Barrier Abnormality Caused by Filaggrin (FLG) Mutations is Associated with Increased Serum 25-hydroxyvitamin D Concentrations The Journal of Allergy and Clinical Immunology. Nov, 2012 | Pubmed ID: 22921868 "To Wheeze or Not to Wheeze": That is Not the Question The Journal of Allergy and Clinical Immunology. Aug, 2012 | Pubmed ID: 22766098 Common Variants at 12q15 and 12q24 Are Associated with Infant Head Circumference Nature Genetics. Apr, 2012 | Pubmed ID: 22504419 Interaction Between Asthma and Lung Function Growth in Early Life American Journal of Respiratory and Critical Care Medicine. Jun, 2012 | Pubmed ID: 22461370 Coarse and Fine Particles but Not Ultrafine Particles in Urban Air Trigger Hospital Admission for Asthma in Children Thorax. Mar, 2012 | Pubmed ID: 22156960 Interaction Between Filaggrin Null Mutations and Tobacco Smoking in Relation to Asthma The Journal of Allergy and Clinical Immunology. Feb, 2012 | Pubmed ID: 22088612 Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid is Skewed by Maternal Atopy American Journal of Respiratory and Critical Care Medicine. Feb, 2012 | Pubmed ID: 22077068 Long-term Exposure to Air Pollution and Asthma Hospitalisations in Older Adults: a Cohort Study Thorax. Jan, 2012 | Pubmed ID: 21890573 Méta-analyse Des études D'association Pangénomique Identifie Trois Loci De Risques Nouveaux Pour La Dermatite Atopique Nature Genetics. 2011 | Pubmed ID: 22197932 Reduced Diversity of the Intestinal Microbiota During Infancy is Associated with Increased Risk of Allergic Disease at School Age The Journal of Allergy and Clinical Immunology. Sep, 2011 | Pubmed ID: 21782228 Robustness of Genome-wide Scanning Using Archived Dried Blood Spot Samples As a DNA Source BMC Genetics. Jul, 2011 | Pubmed ID: 21726430 Elevated Eosinophil Protein X in Urine from Healthy Neonates Precedes Development of Atopy in the First 6 Years of Life American Journal of Respiratory and Critical Care Medicine. Sep, 2011 | Pubmed ID: 21680952 Endotyping Early Childhood Asthma by Quantitative Symptom Assessment The Journal of Allergy and Clinical Immunology. May, 2011 | Pubmed ID: 21439619 Predictors of Indoor Fine Particulate Matter in Infants' Bedrooms in Denmark Environmental Research. Jan, 2011 | Pubmed ID: 21059467 Association of Bacteria and Viruses with Wheezy Episodes in Young Children: Prospective Birth Cohort Study BMJ (Clinical Research Ed.). Oct, 2010 | Pubmed ID: 20921080 Transfer of Maternal IgE Can Be a Common Cause of Increased IgE Levels in Cord Blood The Journal of Allergy and Clinical Immunology. Sep, 2010 | Pubmed ID: 20816197 Children with Allergic and Nonallergic Rhinitis Have a Similar Risk of Asthma The Journal of Allergy and Clinical Immunology. Sep, 2010 | Pubmed ID: 20816191 Long-term Studies of the Natural History of Asthma in Childhood The Journal of Allergy and Clinical Immunology. Aug, 2010 | Pubmed ID: 20688204 Filaggrin Gene Variants and Atopic Diseases in Early Childhood Assessed Longitudinally from Birth Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. Sep, 2010 | Pubmed ID: 20573035 A Novel Method for Assessing Unchallenged Levels of Mediators in Nasal Epithelial Lining Fluid The Journal of Allergy and Clinical Immunology. Jun, 2010 | Pubmed ID: 20304470 Elevated Exhaled Nitric Oxide in High-risk Neonates Precedes Transient Early but Not Persistent Wheeze American Journal of Respiratory and Critical Care Medicine. Jul, 2010 | Pubmed ID: 20299533 Increased Risk of Eczema but Reduced Risk of Early Wheezy Disorder from Exclusive Breast-feeding in High-risk Infants The Journal of Allergy and Clinical Immunology. Apr, 2010 | Pubmed ID: 20236698 Variants of DENND1B Associated with Asthma in Children The New England Journal of Medicine. Jan, 2010 | Pubmed ID: 20032318 17q12-21 Variants Interact with Smoke Exposure As a Risk Factor for Pediatric Asthma but Are Equally Associated with Early-onset Versus Late-onset Asthma in North Americans of European Ancestry The Journal of Allergy and Clinical Immunology. Sep, 2009 | Pubmed ID: 19660801 Chromosome 17q21 Gene Variants Are Associated with Asthma and Exacerbations but Not Atopy in Early Childhood American Journal of Respiratory and Critical Care Medicine. Feb, 2009 | Pubmed ID: 19029000 Early Bioavailability of Inhaled Salbutamol Reflects Lung Dose in Children British Journal of Clinical Pharmacology. Oct, 2008 | Pubmed ID: 18637892 Gene-environment Interaction in the Onset of Eczema in Infancy: Filaggrin Loss-of-function Mutations Enhanced by Neonatal Cat Exposure PLoS Medicine. Jun, 2008 | Pubmed ID: 18578563 Sensitization Does Not Develop in Utero The Journal of Allergy and Clinical Immunology. Mar, 2008 | Pubmed ID: 18328892 Extrapolating Evidence Beyond Age Groups The Journal of Allergy and Clinical Immunology. Apr, 2008 | Pubmed ID: 18325574 Childhood Asthma After Bacterial Colonization of the Airway in Neonates The New England Journal of Medicine. Oct, 2007 | Pubmed ID: 17928596 Age Dependent Systemic Exposure to Inhaled Salbutamol British Journal of Clinical Pharmacology. Aug, 2007 | Pubmed ID: 17335545 Échantillonnage non invasive de muqueuse liquide pour la Quantification des niveaux d’immunitaire-médiateur In Vivo des voies respiratoires supérieures Helene M. Wolsk1, Bo L. Chawes1, Jonathan Thorsen1, Jakob Stokholm1, Klaus Bønnelykke1, Susanne Brix2, Hans Bisgaard1 1Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, 2Department of Biotechnology and Biomedicine, Technical University of Denmark JoVE 55800 Immunology and Infection
Échantillonnage non invasive de muqueuse liquide pour la Quantification des niveaux d’immunitaire-médiateur In Vivo des voies respiratoires supérieures Helene M. Wolsk1, Bo L. Chawes1, Jonathan Thorsen1, Jakob Stokholm1, Klaus Bønnelykke1, Susanne Brix2, Hans Bisgaard1 1Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, 2Department of Biotechnology and Biomedicine, Technical University of Denmark JoVE 55800 Immunology and Infection
