Larry A. Sklar Center for Molecular Discovery University of New Mexico Health Sciences Center Biography Publications Institution JoVE Articles Larry A. Sklar has not added a biography. If you are Larry A. Sklar and would like to personalize this page please email our Author Liaison for assistance. Publications A Phenotypic Screen for Compounds That Reverse CAMP-mediated Suppression of T Cell Functions SLAS Discovery : Advancing Life Sciences R & D. Jul, 2022 | Pubmed ID: 35385793 RUNX2 Regulates Leukemic Cell Metabolism and Chemotaxis in High-risk T Cell Acute Lymphoblastic Leukemia The Journal of Clinical Investigation. Mar, 2021 | Pubmed ID: 33555272 Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties Journal of Medicinal Chemistry. Oct, 2020 | Pubmed ID: 32902275 Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy Cell Reports. Feb, 2020 | Pubmed ID: 32049011 A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling Cell Chemical Biology. Dec, 2019 | Pubmed ID: 31706983 Autophagy, Inflammation, and Metabolism (AIM) Center in Its Second Year Autophagy. Oct, 2019 | Pubmed ID: 31234750 Clioquinol: To Harm or Heal Pharmacology & Therapeutics. Jul, 2019 | Pubmed ID: 30898518 Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: Supporting the Next Generation of Autophagy Researchers and Fostering International Collaborations Autophagy. 2018 | Pubmed ID: 29938597 High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining SLAS Discovery : Advancing Life Sciences R & D. Aug, 2018 | Pubmed ID: 29232168 A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27316999 Cyclic AMP Efflux Inhibitors As Potential Therapeutic Agents for Leukemia Oncotarget. Jun, 2016 | Pubmed ID: 27129155 Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair Journal of Biomolecular Screening. Jan, 2016 | Pubmed ID: 26442911 Novel Activities of Select NSAID R-Enantiomers Against Rac1 and Cdc42 GTPases PloS One. 2015 | Pubmed ID: 26558612 FRET Detection of Lymphocyte Function-associated Antigen-1 Conformational Extension Molecular Biology of the Cell. Jan, 2015 | Pubmed ID: 25378583 A High Throughput Flow Cytometric Assay Platform Targeting Transporter Inhibition Drug Discovery Today. Technologies. Jun, 2014 | Pubmed ID: 25027381 Identification of Isoxsuprine Hydrochloride As a Neuroprotectant in Ischemic Stroke Through Cell-based High-throughput Screening PloS One. 2014 | Pubmed ID: 24804769 The University of New Mexico Center for Molecular Discovery Combinatorial Chemistry & High Throughput Screening. Mar, 2014 | Pubmed ID: 24409953 Fluorescent Substrates for Flow Cytometric Evaluation of Efflux Inhibition in ABCB1, ABCC1, and ABCG2 Transporters Analytical Biochemistry. Jun, 2013 | Pubmed ID: 23470221 Characterization of a Cdc42 Protein Inhibitor and Its Use As a Molecular Probe The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23382385 Flow Cytometry for Drug Discovery, Receptor Pharmacology and High-throughput Screening Current Opinion in Pharmacology. Oct, 2007 | Pubmed ID: 17652026 Flow Cytometric Analysis of Ligand-receptor Interactions and Molecular Assemblies Annual Review of Biophysics and Biomolecular Structure. 2002 | Pubmed ID: 11988464 Solubilization and Display of G Protein-coupled Receptors on Beads for Real-time Fluorescence and Flow Cytometric Analysis BioTechniques. May, 2000 | Pubmed ID: 10818705 Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation (Video) | JoVE Ziming Cao1, Matthew J. Garcia2, Larry A. Sklar2,3,4,5, Angela Wandinger-Ness3,4, Zhichao Fan1 1Department of Immunology, School of Medicine, UConn Health, 2Center for Molecular Discovery, University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center, University of New Mexico Health Sciences Center, 4Department of Pathology, University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center, University of New Mexico JoVE 64401 Immunology and Infection
Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation (Video) | JoVE Ziming Cao1, Matthew J. Garcia2, Larry A. Sklar2,3,4,5, Angela Wandinger-Ness3,4, Zhichao Fan1 1Department of Immunology, School of Medicine, UConn Health, 2Center for Molecular Discovery, University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center, University of New Mexico Health Sciences Center, 4Department of Pathology, University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center, University of New Mexico JoVE 64401 Immunology and Infection
