Lauren O. Bakaletz Center for Microbial Pathogenesis The Research Institute at Nationwide Children's Hospital Biography Publications Institution JoVE Articles Lauren O. Bakaletz has not added a biography. If you are Lauren O. Bakaletz and would like to personalize this page please email our Author Liaison for assistance. Publications Nontypeable Haemophilus Influenzae Type IV Pili: Biological Roles of the Products Encoded by the Pil and Com Operons Journal of Bacteriology. Feb, 2012 | Pubmed ID: 22328674 Use of the Chinchilla Model for Nasopharyngeal Colonization To Study Gene Expression by Moraxella Catarrhalis Infection and Immunity. Mar, 2012 | Pubmed ID: 22184412 Heme Utilization by Nontypeable Haemophilus Influenzae is Essential and Dependent on Sap Transporter Function Journal of Bacteriology. May, 2011 | Pubmed ID: 21441512 Abrogation of Nontypeable Haemophilus Influenzae Protein D Function Reduces Phosphorylcholine Decoration, Adherence to Airway Epithelial Cells, and Fitness in a Chinchilla Model of Otitis Media Vaccine. Feb, 2011 | Pubmed ID: 21167861 The Multifunctional Host Defense Peptide SPLUNC1 is Critical for Homeostasis of the Mammalian Upper Airway PloS One. 2010 | Pubmed ID: 20949060 Mapping the Anatomy of Respiratory Syncytial Virus Infection of the Upper Airways in Chinchillas (Chinchilla Lanigera) Comparative Medicine. Jun, 2010 | Pubmed ID: 20579438 Immunopathogenesis of Polymicrobial Otitis Media Journal of Leukocyte Biology. Feb, 2010 | Pubmed ID: 19843575 Microbial Interactions in the Respiratory Tract The Pediatric Infectious Disease Journal. Oct, 2009 | Pubmed ID: 19918134 Epitope Mapping Immunodominant Regions of the PilA Protein of Nontypeable Haemophilus Influenzae (NTHI) to Facilitate the Design of Two Novel Chimeric Vaccine Candidates Vaccine. Dec, 2009 | Pubmed ID: 19699813 Chinchilla As a Robust, Reproducible and Polymicrobial Model of Otitis Media and Its Prevention Expert Review of Vaccines. Aug, 2009 | Pubmed ID: 19627188 Respiratory Syncytial Virus-induced Dysregulation of Expression of a Mucosal Beta-defensin Augments Colonization of the Upper Airway by Non-typeable Haemophilus Influenzae Cellular Microbiology. Sep, 2009 | Pubmed ID: 19500108 The Heme-binding Protein (HbpA) of Haemophilus Influenzae As a Virulence Determinant International Journal of Medical Microbiology : IJMM. Nov, 2009 | Pubmed ID: 19451029 Nontypeable Haemophilus Influenzae As a Pathogen in Children The Pediatric Infectious Disease Journal. Jan, 2009 | Pubmed ID: 19057458 Innate Immune Defenses: Finding a New Way to Calm the Storm Immunology and Cell Biology. Nov-Dec, 2008 | Pubmed ID: 18794905 Differential Uptake and Processing of a Haemophilus Influenzae P5-derived Immunogen by Chinchilla Dendritic Cells Infection and Immunity. Mar, 2008 | Pubmed ID: 18160476 A Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 Homologue Plays a Pivotal Role in Nontypeable Haemophilus Influenzae Colonization of the Chinchilla Nasopharynx Via the Outer Membrane Protein P5-homologous Adhesin Infection and Immunity. Jan, 2008 | Pubmed ID: 17938212 Bacterial Biofilms in Otitis Media: Evidence and Relevance The Pediatric Infectious Disease Journal. Oct, 2007 | Pubmed ID: 18049376 Contribution of Moraxella Catarrhalis Type IV Pili to Nasopharyngeal Colonization and Biofilm Formation Infection and Immunity. Dec, 2007 | Pubmed ID: 17908808 The PilA Protein of Non-typeable Haemophilus Influenzae Plays a Role in Biofilm Formation, Adherence to Epithelial Cells and Colonization of the Mammalian Upper Respiratory Tract Molecular Microbiology. Sep, 2007 | Pubmed ID: 17645732 Differential Type I Interferon Induction by Respiratory Syncytial Virus and Influenza a Virus in Vivo Journal of Virology. Sep, 2007 | Pubmed ID: 17626092 Biofilms Formed by Nontypeable Haemophilus Influenzae in Vivo Contain Both Double-stranded DNA and Type IV Pilin Protein Journal of Bacteriology. May, 2007 | Pubmed ID: 17322318 The OxyR Regulon in Nontypeable Haemophilus Influenzae Journal of Bacteriology. Feb, 2007 | Pubmed ID: 17142400 Phosphorylcholine Decreases Early Inflammation and Promotes the Establishment of Stable Biofilm Communities of Nontypeable Haemophilus Influenzae Strain 86-028NP in a Chinchilla Model of Otitis Media Infection and Immunity. Feb, 2007 | Pubmed ID: 17130253 A Member of the Cathelicidin Family of Antimicrobial Peptides is Produced in the Upper Airway of the Chinchilla and Its MRNA Expression is Altered by Common Viral and Bacterial Co-pathogens of Otitis Media Molecular Immunology. Mar, 2007 | Pubmed ID: 17113647 The Non-typeable Haemophilus Influenzae Sap Transporter Provides a Mechanism of Antimicrobial Peptide Resistance and SapD-dependent Potassium Acquisition Molecular Microbiology. Dec, 2006 | Pubmed ID: 17064364 Passive Immunization with Human Anti-protein D Antibodies Induced by Polysaccharide Protein D Conjugates Protects Chinchillas Against Otitis Media After Intranasal Challenge with Haemophilus Influenzae Vaccine. May, 2006 | Pubmed ID: 16616975 Food Commensal Microbes As a Potentially Important Avenue in Transmitting Antibiotic Resistance Genes FEMS Microbiology Letters. Jan, 2006 | Pubmed ID: 16445749 Nontypeable Haemophilus Influenzae Adheres to Intercellular Adhesion Molecule 1 (ICAM-1) on Respiratory Epithelial Cells and Upregulates ICAM-1 Expression Infection and Immunity. Feb, 2006 | Pubmed ID: 16428725 Genomic Sequence of an Otitis Media Isolate of Nontypeable Haemophilus Influenzae: Comparative Study with H. Influenzae Serotype D, Strain KW20 Journal of Bacteriology. Jul, 2005 | Pubmed ID: 15968074 Role of Sialic Acid and Complex Carbohydrate Biosynthesis in Biofilm Formation by Nontypeable Haemophilus Influenzae in the Chinchilla Middle Ear Infection and Immunity. Jun, 2005 | Pubmed ID: 15908345 Chinchilla and Murine Models of Upper Respiratory Tract Infections with Respiratory Syncytial Virus Journal of Virology. May, 2005 | Pubmed ID: 15857989 Vaccines for Otitis Media: Proposals for Overcoming Obstacles to Progress Vaccine. Apr, 2005 | Pubmed ID: 15780715 Demonstration of Type IV Pilus Expression and a Twitching Phenotype by Haemophilus Influenzae Infection and Immunity. Mar, 2005 | Pubmed ID: 15731063 Recent Advances in Otitis Media. 6. Vaccine The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700938 Recent Advances in Otitis Media. 5. Microbiology and Immunology The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700937 Recent Advances in Otitis Media. 4C. Interaction Between Middle Ear and Inner Ear in Otitis Media The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700936 Recent Advances in Otitis Media. 4B. Biochemistry The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700935 Recent Advances in Otitis Media. 4A. Molecular Biology The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700934 Recent Advances in Otitis Media. 3. Animal Models; Anatomy and Pathology; Pathogenesis; Cell Biology and Genetics The Annals of Otology, Rhinology & Laryngology. Supplement. Jan, 2005 | Pubmed ID: 15700933 Development of a Chinchilla Model to Allow Direct, Continuous, Biophotonic Imaging of Bioluminescent Nontypeable Haemophilus Influenzae During Experimental Otitis Media Infection and Immunity. Jan, 2005 | Pubmed ID: 15618201 A Mutation in the Sap Operon Attenuates Survival of Nontypeable Haemophilus Influenzae in a Chinchilla Model of Otitis Media Infection and Immunity. Jan, 2005 | Pubmed ID: 15618200 Developing Animal Models for Polymicrobial Diseases Nature Reviews. Microbiology. Jul, 2004 | Pubmed ID: 15197391 Partial Analysis of the Genomes of Two Nontypeable Haemophilus Influenzae Otitis Media Isolates Infection and Immunity. May, 2004 | Pubmed ID: 15102813 Identification and Characterization of a Mucosal Antimicrobial Peptide Expressed by the Chinchilla (Chinchilla Lanigera) Airway The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14996845 Reduced Severity of Middle Ear Infection Caused by Nontypeable Haemophilus Influenzae Lacking the Hemoglobin/hemoglobin-haptoglobin Binding Proteins (Hgp) in a Chinchilla Model of Otitis Media Microbial Pathogenesis. Jan, 2004 | Pubmed ID: 14643637 The Fourth Surface-exposed Region of the Outer Membrane Protein P5-homologous Adhesin of Nontypable Haemophilus Influenzae is an Immunodominant but Nonprotective Decoying Epitope Journal of Immunology (Baltimore, Md. : 1950). Aug, 2003 | Pubmed ID: 12902501 Efficacy of the 26-kilodalton Outer Membrane Protein and Two P5 Fimbrin-derived Immunogens to Induce Clearance of Nontypeable Haemophilus Influenzae from the Rat Middle Ear and Lungs As Well As from the Chinchilla Middle Ear and Nasopharynx Infection and Immunity. Aug, 2003 | Pubmed ID: 12874350 Anatomy of the Nasal Cavity in the Chinchilla Cells, Tissues, Organs. 2003 | Pubmed ID: 12835577 Nontypeable Haemophilus Influenzae Gene Expression Induced in Vivo in a Chinchilla Model of Otitis Media Infection and Immunity. Jun, 2003 | Pubmed ID: 12761130 Detection and Characterization of Pediatric Serum Antibody to the OMP P5-homologous Adhesin of Nontypeable Haemophilus Influenzae During Acute Otitis Media Vaccine. Oct, 2002 | Pubmed ID: 12297406 Tracking the Tissue Distribution of Marker Dye Following Intranasal Delivery in Mice and Chinchillas: a Multifactorial Analysis of Parameters Affecting Nasal Retention Vaccine. Aug, 2002 | Pubmed ID: 12163273 Recent Advances in Otitis Media. 7. Vaccine The Annals of Otology, Rhinology & Laryngology. Supplement. Mar, 2002 | Pubmed ID: 11968864 Recent Advances in Otitis Media. 6. Microbiology and Immunology The Annals of Otology, Rhinology & Laryngology. Supplement. Mar, 2002 | Pubmed ID: 11968862 Recent Advances in Otitis Media. 5. Molecular Biology and Biochemistry The Annals of Otology, Rhinology & Laryngology. Supplement. Mar, 2002 | Pubmed ID: 11968861 Recent Advances in Otitis Media. 4. Anatomy, Cell Biology, Pathology, and Animal Models The Annals of Otology, Rhinology & Laryngology. Supplement. Mar, 2002 | Pubmed ID: 11968860 В пробирке образование биопленки в 8-и палаты слайдов Joseph A. Jurcisek1, Amanda C. Dickson1, Molly E. Bruggeman1, Lauren O. Bakaletz1 1Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital JoVE 2481 Immunology and Infection
В пробирке образование биопленки в 8-и палаты слайдов Joseph A. Jurcisek1, Amanda C. Dickson1, Molly E. Bruggeman1, Lauren O. Bakaletz1 1Center for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital JoVE 2481 Immunology and Infection